予防医学分野

KEYWORDS

コホート研究
栄養
身体活動
社会疫学
口腔と全身

HEAD

若井建志

教授

LAB MEMBER

構成員名	役職	研究者総覧
田村高志	准教授	研究者総覧
永吉真子	講師	研究者総覧
松永貴史	助教	研究者総覧

CONTACT

Email	yobojim◎med.nagoya-u.ac.jp（送信の際は◎を@に変更してください）
HP	予防医学分野独自ホームページ

OUTLINE

　当分野は昭和16年に開設された予防医学講座を引き継ぐ研究教育グループであり、疫学研究により、疾病や健康リスクの解明を目指している。現在の研究はコホート研究が中心であり、現在は2005年から開始され、全国で10万名以上が参加している日本多施設共同コーホート研究（J-MICC Study）の中央事務局を、愛知県がんセンター研究所と共同で務めるとともに、静岡地区（聖隷予防検診センター、浜松市）と大幸研究（医学部保健学科・旧大幸医療センター、名古屋市）、伊賀市コホート研究（伊賀市立上野総合市民病院、伊賀市）での追跡調査を担当している。　
　また、すでに20年間にわたる追跡調査が終了している大規模コホート研究（参加者約11万名）であるJACC Study の事務局も務めており、貴重なデータ資産を幅広い研究者に活用していただくことに努めている。

RESEARCH PROJECTS

日本多施設共同コーホート研究（J-MICC Study）
The Japan Collaborative Cohort Study for Evaluation of Cancer Risk（JACC Study）
歯科医師を対象とした歯と全身の健康、栄養との関連に関するコーホート研究（LEMONADE Study）

BIBLIOGRAPHY

2025

Nakane H, Tamura T, Nagayoshi M, Okada R, Takeuchi K, Nakamura Y, Suzuki S, Takashima N, Koyama T, Arisawa K, Ikezaki H, Tanaka K, Nishimoto D, Momozawa Y, Hamajima N, Tanaka H, Wakai K, Matsuo K, for the J-MICC Study Group. A polymorphism in the DOCK7 gene (rs1167998) is associated with salt restriction behavior in hypertensive patients. Nagoya J Med Sci 2026 May;88(2) (in press).
Kato Y, Tamura T, Wakai K, Kubo Y, Okada R, Matsunaga T, Nagayoshi M, Imaeda N, Goto C, Otonari J, Ikezaki H, Hara M, Nishida Y, Michihata N, Nakamura Y, Tanoue S, Ibusuki R, Suzuki S, Otani T, Koyanagi YN, Ito H, Ozaki E, Watanabe I, Kuriki K, Takashima N, Miyagawa N, Katsuura-Kamano S, Watanabe T, Hishida A, Matsuo K. Associations of vegetable and fruit consumption with all-cause and cause-specific mortality in the Japanese population: the Japan multi- institutional collaborative cohort study. Nutr J. 2025 Nov 22;25(1):2.
Matsunaga T, Kikuchi H, Inoue S, Ihira H, Yamaji T, Iwasaki M, Inoue M, Tsugane S, Sawada N. Moderate-to-vigorous physical activity and total and site- specific cancer: the Japan Public Health Center-based Prospective Study. J Epidemiol. 2025 Oct 4. doi: 10.2188/jea.JE20250041. Epub ahead of print. PMID: 41047348.
Nagayoshi M, Tamai M, Takeuchi K, Yamanashi H, Koyamatsu J, Nonaka F, Nobusue K, Honda Y, Kawashiri SY, Nagata Y, Maeda T. Frequency of Conversation, Laughter and Other Vocalising Opportunities in Daily Life and Maximum Tongue Pressure: The Goto Longevity Study. J Oral Rehabil. 2025 Sep;52(9):1288-1296. doi: 10.1111/joor.13979. Epub 2025 Apr 22. PMID: 40260895; PMCID: PMC12408979.
Sasakabe T, Wakai K, Kawai S, Lin Y, Hishida A, Iso H, Kikuchi S, Tamakoshi A; Japan Collaborative Cohort Study Group. Low-Carbohydrate Diet Score and Risk of Mortality: The Japan Collaborative Cohort Study. J Nutr. 2025 Apr;155(4):1218-1225.
Nagayoshi M, Kachi Y, Kato T, Ochi M, Ichinose Y, Kondo T, Takehara K. Response to the Letter: \"\"Enhancing the Understanding of Paternal Involvement in Childcare and Its Impact on Maternal Disciplinary Practices\"\". J Epidemiol. 2025 May 5;35(5):252-253.
Nagayoshi M, Kachi Y, Kato T, Ochi M, Ichinose Y, Kondo T, Takehara K. Response to the Letter: \"\"Enhancing the Understanding of Paternal Involvement in Childcare and Its Impact on Maternal Disciplinary Practices\"\". J Epidemiol. 2025 May 5;35(5):252-253.

2024

Nagayoshi M, Kachi Y, Kato T, Ochi M, Ichinose Y, Kondo T, Takehara K. Paternal Involvement in Childcare and Housework and Mothers' Spanking Behavior: The Japanese Longitudinal Survey of Newborns in the 21st Century. J Epidemiol. 2024 Dec 5;34(12):577-586. doi: 10.2188/jea.JE20230270. Epub 2024 Oct 31. PMID: 38853010; PMCID: PMC11564066.
Matsunaga T, Wakai K, Imaeda N, Goto C, Tamada Y, Kato Y, Kubo Y, Okada R, Nagayoshi M, Tamura T, Hishida A, Ikezaki H, Otonari J, Takashima N, Miyagawa N, Matsuo K; Japan Multi-Institutional Collaborative Cohort (J-MICC) Study Group. Food group intakes and high-sensitivity C-reactive protein among community- dwelling Japanese adults: a cross-sectional study. Public Health Nutr. 2024 Oct 18;27(1):e212.
Tsukamoto M, Hishida A, Tamura T, Nagayoshi M, Okada R, Kubo Y, Kato Y, Hamajima N, Nishida Y, Shimanoe C, Ibusuki R, Shibuya K, Takashima N, Nakamura Y, Kusakabe M, Nakamura Y, Koyanagi YN, Oze I, Nishiyama T, Suzuki S, Watanabe I, Matsui D, Otonari J, Ikezaki H, Katsuura-Kamano S, Arisawa K, Kuriki K, Nakatochi M, Momozawa Y, Takeuchi K, Wakai K, Matsuo K. GWAS of Folate Metabolism With Gene-environment Interaction Analysis Revealed the Possible Role of Lifestyles in the Control of Blood Folate Metabolites in Japanese: The J-MICC Study. J Epidemiol. 2024 May 5;34(5):228-237.
Kasahara C, Tamura T, Wakai K, Tamada Y, Kato Y, Kubo Y, Okada R, Nagayoshi M, Hishida A, Imaeda N, Goto C, Otonari J, Ikezaki H, Nishida Y, Shimanoe C, Oze I, Koyanagi YN, Nakamura Y, Kusakabe M, Nishimoto D, Shimoshikiryo I, Suzuki S, Watanabe M, Ozaki E, Omichi C, Kuriki K, Takashima N, Miyagawa N, Arisawa K, Katsuura-Kamano S, Takeuchi K, Matsuo K; J-MICC Study Group. Association between consumption of small fish and all-cause mortality among Japanese: the Japan Multi-Institutional Collaborative Cohort Study. Public Health Nutr. 2024 May 3;27(1):e135.

2023

Tamura T, Wakai K, Kato Y, Tamada Y, Kubo Y, Okada R, Nagayoshi M, Hishida A, Imaeda N, Goto C, Ikezaki H, Otonari J, Hara M, Tanaka K, Nakamura Y, Kusakabe M, Ibusuki R, Koriyama C, Oze I, Ito H, Suzuki S, Nakagawa-Senda H, Ozaki E, Matsui D, Kuriki K, Kondo K, Takashima N, Watanabe T, Katsuura-Kamano S, Matsuo K; Japan Multi-Institutional Collaborative Cohort (J-MICC) Study. Dietary Carbohydrate and Fat Intakes and Risk of Mortality in the Japanese Population: the Japan Multi-Institutional Collaborative Cohort Study. J Nutr. 2023 Aug;153(8):2352-2368.
Nagayoshi M, Hishida A, Shimizu T, Kato Y, Kubo Y, Okada R, Tamura T, Otonari J, Ikezaki H, Hara M, Nishida Y, Oze I, Koyanagi YN, Nakamura Y, Kusakabe M, Ibusuki R, Shibuya K, Suzuki S, Nishiyama T, Koyama T, Ozaki E, Kuriki K, Takashima N, Nakamura Y, Katsuura-Kamano S, Arisawa K, Nakatochi M, Momozawa Y, Takeuchi K, Wakai K. BMI and Cardiometabolic Traits in Japanese: A Mendelian Randomization Study. J Epidemiol. 2024 Feb 5;34(2):51-62. doi: 10.2188/jea.JE20220154. Epub 2023 May 31. PMID: 36709979; PMCID: PMC10751192.
Nagayoshi M, Takeuchi K, Tamada Y, Kato Y, Kubo Y, Okada R, Tamura T, Hishida A, Otonari J, Ikezaki H, Nishida Y, Shimanoe C, Koyanagi YN, Matsuo K, Mikami H, Kusakabe M, Nishimoto D, Shibuya K, Suzuki S, Nishiyama T, Ozaki E, Watanabe I, Kuriki K, Takashima N, Kadota A, Arisawa K, Katsuura-Kamano S, Wakai K. Sex-specific Relationship Between Stress Coping Strategies and All-cause Mortality: Japan Multi-Institutional Collaborative Cohort Study. J Epidemiol. 2023 May 5;33(5):236-245.\t