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産学協同研究講座希少性・難治性がん解析研究講座

概要

　名古屋大学大学院医学系研究科は、2020年1月に、希少性・難治性がん解析研究講座を新たに設置しました。本研究講座は、尿中腫瘍マーカーを用いて、従来検査が困難であった希少性・難治性がんの新しい診断技術を開発することを目的としています。

　これまで名古屋大学医学系研究科小児外科は、日立製作所と共同で、尿中腫瘍マーカーによるがん検査の研究を行ってきました。その結果、尿中代謝物の網羅的解析技術、尿中腫瘍マーカーの抽出技術を踏まえたがん検査モデルにより、いろいろながん腫においてがん患者と健常者を識別できることがわかってきました。加えて、複数の尿中腫瘍マーカーによる代謝物パネル検査法という独自の方法を新たに開発し、良性腫瘍が抽出できる可能性を見出しています。

　本研究講座では、この新しい取り組みを通して、全国の拠点病院と連携しながら、がんの早期診断と患者のQoLを両立させる新しい社会の構築を目指します。

設置期間：令和2年1月～令和6年3月

名古屋大学希少性・難治性がん解析研究講座がスタート ～新しい診断法実用化に向け臨床研究加速～

研究プロジェクト

プレスリリース

新たな神経芽腫尿中バイオマーカーの特定　原著論文

国際学会

  • 2023 ASPHO Conference (May 10-13,2023) The American Society of Pediatric Hematology/Oncology(米国小児血液腫瘍学会)
    • Clinical validation of novel urinary markers for neuroblastoma diagnosis
    Hizuru Amano, Hiroo Uchida, Kazuharu Harada, Atsushi Narita, Shun Kumano, Mayumi Abe, Minoru Sakairi, Chiyoe Shirota, Takahisa Tainaka, Wataru Sumida, Kazuki Yokota, Satoshi Makita, Tsuyoshi Osawa, Masataka Taguri, Yoshiyuki Takahashi, Akinari Hinoki
  • AACR ANNUAL MEETING 2023（April 14-19,2023）American Association for Cancer Research(米国癌学会)
    • Novel urinary marker for diagnosis and prognosis of neuroblastoma
    Akinari Hinoki, Hizuru Amano, Hiroo Uchida, Atsushi Narita, Shun Kumano, Mayumi Abe, Minoru Sakairi, Chiyoe Shirota, Wataru Sumida, Satoshi Makita, Yoshiyuki Takahashi, Tsuyoshi Osawa.
  • 35th International Symposium on Pediatric Surgical Research. 2022/10/21-23, Osaka, Japan
    URINARY METABOLITES AS BIOMARKERS FOR CHILDHOOD RHABDOMYOSARCOMA.
    Nakano S, Uchida H, Amano H, Sakairi M,Maeda N, Fumino S, Yamada Y,Narita A, Takahashi Y, Osawa T, Hinoki A.
  • AACR ANNUAL MEETING 2022. 2022/4/8-13, New Orleans, USA
    Novel biomarker discovery for pancreatic cancer using urinary metabolites.
    Hizuru Amano, Hiroo Uchida, Masamichi Hayashi, Tsuyoshi Osawa, Masaya Yamanaka, Mayumi Abe, Takashi Ishigaki, Chiyoe Shirota, Wataru Sumida, Satoshi Makita, Aitaro Takimoto, Masamune Okamoto, Akihiro Yasui, Yoichi Nakagawa, Minoru Sakairi, Yasushi Terui, Yasuhiro Kodera, Akinari Hinoki.
  • 2022 ASPHO Conference (May 4-7, 2022) The American Society of Pediatric Hematology/Oncology(米国小児血液腫瘍学会)
    METABOLOMICS OF URINARY METABOLITES IN CHILDHOOD RHABDOMYOSARCOMA TO DISCOVER NOVEL BIOMARKERS
    Satoshi Nakano, Hiroo Uchida, Hizuru Amano, Atsushi Narita, Mayumi Abe, Takashi Ishigaki, Minoru Sakairi, Chiyoe Shirota, Wataru Sumida, Satoshi Makita, Aitaro Takimoto, Masamune Okamoto, Akihiro Yasui, Syunya Takada, Yoichi Nakagawa, Yasushi Terui, Masaki Sunagawa, Yoshiyuki Takahashi, Tsuyoshi Osawa, Akinari Hinoki.
  • 2021 ASCO ANNUAL MEETING (June20-23,2021) American Society of Clinical Oncology(米国臨床腫瘍学会)
    Urinary Biomarkers for Monitoring Treatment Response in Neuroblastoma Patients
    Hizuru Amano, Akinari Hinoki, Takashi Ishigaki, Mayumi Abe, Hiroo Uchida , Hirohisa Oda , Minoru Sakairi, Yasushi Terui
  • EACR2021 Virtual Congress (June09-12,2021) European Association for Cancer Research(欧州癌研究会議)
    Identification of urinary biomarker candidates of nephroblastoma
    Hizuru Amano, Akinari Hinoki, Takashi Ishigaki, Mayumi Abe, Hiroo Uchida , Hirohisa Oda , Minoru Sakairi, Yasushi Terui
  • AACR ANNUAL MEETING 2021（April9-14,2021）American Association for Cancer Research(米国癌学会)
    Development of a novel diagnostic system for bile duct cancer using urinary metabolites
    Hizuru Amano, Akinari Hinoki, Takashi Ishigaki, Mayumi Abe, Hiroo Uchida, Hirohisa Oda, Minoru Sakairi, Yasushi Terui
  • 2021 ASPHO Conference (April4-8,2021) The American Society of Pediatric Hematology/Oncology(米国小児血液腫瘍学会)
    NOVEL BIOMARKER DISCOVERY FOR CHILDHOOD RHABDOMYOSARCOMA USING URINARY METABOLITES
    Hizuru Amano, Akinari Hinoki, Takashi Ishigaki, Mayumi Abe, Hiroo Uchida , Hirohisa Oda , Minoru Sakairi, Yasushi Terui

国内学会

  • 第24回 日本外科学会定期学術集会（2024年4月18日～20日） 神経芽腫悪性度予測マーカーのエビデンス創出と保険収載による臨床応用
  • 2024年JCCG神経芽腫委員会（JNBSG）運営委員会（AMED檜山班会議分科会）報告会（2024年1月22,26日）関連研究　新規尿代謝マーカー
  • 第32回 日本コンピュータ外科学会大会（2023年12月1日～3日）名古屋大学小児外科の医療機器開発を目指した医工連携の取り組み
  • 第82回 日本癌学会学術総会（2023年9月21日～23日）Inverse Pairs Boosting(IPB): 尿中代謝物から早期癌を診断する新規メタボローム解析法
  • 第59回 日本小児外科学会学術集会（2022年5月19日～21日） 横紋筋肉腫/腎芽腫/神経芽腫尿中代謝物のCE/MS 解析
  • 第59回 日本小児外科学会学術集会（2022年5月19日～21日）横紋筋肉腫の尿中代謝物解析
  • 第59回 日本小児外科学会学術集会（2022年5月19日～21日）尿中代謝物(MTS，VLA，MTR)による新たな神経芽腫腫瘍マーカーの可能性
  • 第59回 日本小児外科学会学術集会（2022年5月19日～21日）尿中代謝物(MTS，VLA，MTR)による悪性度予測マーカーの可能性
  • 第63回日本小児血液・がん学会学術集会（2021年11 月25 日～11 月27日）神経芽腫における尿中バイオマーカー
  • 第68回日本臨床検査医学会学術集会（2021年11 月11 日～11 月14日）質量分析計を用いた尿中代謝物のメタボロミクスによる新規がん診断法の可能性
  • 第83回日本臨床外科学会総会（2021年11 月18日）名古屋大学・(株)日立製作所 産学協同研究講座（希少性/難治性がん解析研究講座）の医工連携
  • 第48回日本小児栄養消化器肝臓学会（2021年10 月1 日～10 月3日）多施設研究のススメ~小児外科分野から~
  • 第58回日本小児外科学会学術集会The 58th Annual Congress of the Japanese Society of Pediatric Surgeons(JSPS2021) （2021年4 月28 日～4 月30日）神経芽腫の尿中代謝物の安定性
  • 第58回日本小児外科学会学術集会The 58th Annual Congress of the Japanese Society of Pediatric Surgeons(JSPS2021) （2021年4月28日～4月30日）4つの代謝物による神経芽腫超低リスク群の予測
  • 第58回日本小児外科学会学術集会The 58th Annual Congress of the Japanese Society of Pediatric Surgeons(JSPS2021) （2021年4 月28 日～4 月30日）尿中代謝物による神経芽腫のリスク分類
  • 第36回日本小児外科学会秋季シンポジウム（2020年11 月5 日～26日）名古屋大学小児外科と希少性・難治性がん解析研究講座（日立製作所産学共同研究講座）の医療機器開発と医工連携

受賞歴

  • 第58回日本小児外科学会学術集会PSIプライズ　横田一樹
    Yokota K, Hinoki A, Hiramatsu K, Amano H, Kawamura M, Kuwatsuka Y, Tainaka T, Shirota C, Sumida W, Makita S, Okamoto M, Takimoto A, Yasui A, Nakagawa Y, Uchida H, Kawakita M. Urinary N1,N12-diacetylspermine as a biomarker for pediatric cancer: a case-control study. Pediatr Surg Int. 2021 Dec;37(12):1659-1665. doi: 10.1007/s00383-021-04987-y. Epub 2021 Aug 28. PMID: 34453590.

産業財産権

  • 胆道がん検査方法　国立大学法人東海国立大学機構,株式会社日立製作所,日立ハイテク
    出願未公開 2022-090965　登録日：令和4年6月3日
  • 新規検査開発サーバ及び新規検査開発方法　国立大学法人東海国立大学機構,株式会社日立製作所
    特願2020-24153　登録日：令和2年2月17日
  • 尿中腫瘍マーカーによるがん検出方法、キット及び装置　国立大学法人東海国立大学機構,株式会社日立製作所
    特許第7226732号　登録日：令和5年2月13日
  • 小児がん検査用尿中代謝物マーカー　国立大学法人東海国立大学機構,株式会社日立製作所
    特許第7016079号　登録日：令和4年1月27日

研究費採択

  • 国立研究開発法人日本医療研究開発機構　令和5年度 「革新的がん医療実用化研究事業」
    【領域1】がんの本態解明に関する研究
    【領域1-15】がんの本態解明に基づいた新規診断技術・革新的創薬等の開発に資する挑戦的研究 【若手育成枠】
    がん悪液質に伴う代謝異常に基づく早期膵癌・胆道癌診断AIの開発
  • 国立研究開発法人日本医療研究開発機構　令和5年度 「革新的がん医療実用化研究事業」
    【領域4】患者に優しい新規医療技術開発に関する研究
    【領域4-1】バイオマーカーを用いた診断技術の確立と実用化に関する研究【若手育成枠】
    神経芽腫及び褐色細胞腫における3-Methoxytyramine sulfate/3-Methoxytyramine定量技術の確立と実用化
  • 国立研究開発法人日本医療研究開発機構　令和5年度 「橋渡し研究プログラム」
    【シーズA】胆管癌の早期診断を可能にする網羅的尿中メタボローム解析手法の開発
  • 国立研究開発法人日本医療研究開発機構　令和3年度 「橋渡し研究戦略的推進プログラム」
    【シーズA】小児がん（神経芽腫）の個体差を識別可能なメタボロミクスを利用したパネル検査法の開発
  • 国立研究開発法人日本医療研究開発機構　令和3年度 「次世代がん医療創成研究事業」
    【領域D】（診断/バイオマーカー）標的探索研究タイプ
    患者に優しい高感度・高精度ながん診断法の研究
    進行リスクを判別する神経芽腫腫瘍マーカーの開発
  • 2023年度　科研費基盤研究(C)　2023-2025「チロシン系代謝物マーカーによる神経芽腫MYC遺伝子増幅判別モデルの改良と検証」
  • 2022年度　科研費基盤研究(C)　2022-2024「横紋筋肉腫メタボローム解析（尿/組織）による診断マーカーとオンコメタボライト探索」
  • 2022年度　科研費基盤研究(C)　2022-2024「腎芽腫メタボローム解析（尿/組織）による診断マーカーとオンコメタボライト探索」　
  • 2021年度　科研費基盤研究(C)　2021-2023「小児がんの診断治療に資する新規蛍光プローブの開発研究」
  • 2021年度　科研費基盤研究(C)　2021-2023「one carbon metabolismによる膵癌制御の可能性」
  • 2021年度　科研費基盤研究(C)　2021-2023「腎芽腫患児の代謝物網羅解析によるバイオマーカーの探索と創薬への挑戦」
  • 2021年度　研究活動スタート支援　2021-2022「新規神経芽腫マーカー3-MTSによるリスク分類の有効性検証」
  • 2020年度　科研費若手研究　2020-2021「尿中マルチ腫瘍マーカーを用いた胆道がんの早期発見」
  • Nagoya University Global Multi-Campus Seed Funding Grants 2023
    • Advancing Rhabdomyosarcoma Research and Developing Novel Diagnostic and Therapeutic Strategies and Fostering the Partnership between Nagoya University and The University of Freiburg
  • 2022年度　東海国立大学機構　融合フロンティア次世代研究事業（融合フロンティア次世代リサーチャー）Comprehensive analysis of tumor micro-environment and oncogenic adaptation in sarcoma cells.
  • 公益財団法人 がんの子どもを守る会　2021年海外留学助成事業
    肉腫細胞における腫瘍微小環境と発癌適用の包括的解析
  • 2021年度　名古屋大学　卓越大学院プログラム（文部科学省補助金事業）
    Convolution of Informatics and Biomedical Sciences on Glocal Alliances (CIBoG)
  • 2021年度　東海広域5大学ベンチャー起業支援
    スタートアップ　：尿中代謝物を用いた希少性・難治性がん（小児がん、胆道がん、すい臓がん、肉腫）の早期診断、治療効果予測を実現する診断法の開発
  • 2021年度　堀科学芸術振興財団　第30回研究助成
    後腹膜脂肪肉腫の代謝産物解析によるがん関連代謝産物の同定

教員

構成員名役職所属
檜　顕成 特任教授 希少性・難治性がん解析研究講座、小児外科
天野　日出 特任講師 希少性・難治性がん解析研究講座、小児外科
熊野　峻 客員教授 希少性・難治性がん解析研究講座
高田　安章 産学連携研究員 希少性・難治性がん解析研究講座
坂入　実 客員教授 希少性・難治性がん解析研究講座

研究実績

  • 2024年
    1. Shirota C, Hinoki A, Tainaka T, Sumida W, Makita S, Amano H, Takimoto A, Yasui A, Nakagawa Y, Liu J, Guo Y, Kato D, Goda Y, Maeda T, Uchida H. Surgical Strategies for Neonates with Prenatally Diagnosed Congenital Biliary Dilatation. J Pediatr Surg. 2024 Mar;59(3):385-388. doi: 10.1016/j.jpedsurg.2023.10.045. Epub 2023 Oct 20. PMID: 37968151.
    2. Kato D, Uchida H, Tainaka T, Amano H, Ono Y, Yasui A, Shirota C, Sumida W, Yokota K, Makita S, Takimoto A, Takada S, Nakagawa Y, Gohda Y, Maeda T, Hinoki A. Laparoscopic Fundoplication in Patients with Ventriculoperitoneal Shunts: A Systematic Review and Our Experience. J Laparoendosc Adv Surg Tech A. 2024 Jan 30. doi: 10.1089/lap.2023.0220. Epub ahead of print. PMID: 38289289.
  • 2023年
    1. Uchida H, Tiao GM, Shivakumar P, Wong KKY, Asai A, Amano H. Editorial: Infants with cholestasis. Front Pediatr. 2023 Mar 28;11:1175231. doi: 10.3389/fped.2023.1175231. PMID: 37056945; PMCID: PMC10086434.
    2. Oshima K, Hinoki A, Uchida H, Tanaka Y, Okuno Y, Go Y, Shirota C, Tainaka T, Sumida W, Yokota K, Makita S, Takimoto A, Kano Y, Sawa S. Single-cell RNA sequencing of intestinal immune cells in neonatal necrotizing enterocolitis. Pediatr Surg Int. 2023 Apr 11;39(1):179. doi: 10.1007/s00383-023-05461-7. PMID: 37041419.
    3. Sumida W, Yasui A, Shirota C, Makita S, Okamoto M, Ogata S, Takimoto A, Takada S, Nakagawa Y, Kato D, Gohda Y, Amano H, Guo Y, Hinoki A, Uchida H. Update on aortopexy and posterior tracheopexy for tracheomalacia in patients with esophageal atresia. Surg Today. 2023 Feb 2. doi: 10.1007/s00595-023-02652-6. Epub ahead of print. PMID: 36729255.
    4. Yokoyama S, Ishizu Y, Honda T, Imai N, Ito T, Yamamoto K, Hinoki A, Sumida W, Shirota C, Tainaka T, Makita S, Yokota K, Uchida H, Ishigami M. Endoscopic injection sclerotherapy with polidocanol for cardiac varices in children and adolescents. Arch Pediatr. 2023 Feb;30(2):109-112. doi: 10.1016/j.arcped.2022.11.016. Epub 2022 Dec 9. PMID: 36509625.
    5. Gohda Y, Yokota K, Uchida H, Shirota C, Tainaka T, Sumida W, Makita S, Takimoto A, Takada S, Nakagawa Y, Maeda T, Guo Y, Hinoki A. Safe thoracoscopic repair of recurrent congenital diaphragmatic hernia after initial open abdominal repair. Surg Today. 2023 Oct 13. doi: 10.1007/s00595-023-02757-y. Epub ahead of print. PMID: 37831144.
    6. Shirota C, Hinoki A, Tainaka T, Sumida W, Makita S, Amano H, Takimoto A, Yasui A, Nakagawa Y, Liu J, Guo Y, Kato D, Goda Y, Maeda T, Uchida H. Surgical Strategies for Neonates with Prenatally Diagnosed Congenital Biliary Dilatation. J Pediatr Surg. 2024 Mar;59(3):385-388. doi: 10.1016/j.jpedsurg.2023.10.045. Epub 2023 Oct 20. PMID: 37968151.
    7. Takimoto A, Amano H, Shirota C, Sumida W, Makita S, Okamoto M, Ogata S, Takada S, Nakagawa Y, Kato D, Gohda Y, Hinoki A, Uchida H. Hemi-circumferential mucosal resection and anastomosis procedure for rectal prolapse following anorectoplasty for anorectal malformations. Surg Today. 2023 May;53(5):628-632. doi: 10.1007/s00595-022-02611-7. Epub 2022 Oct 25. PMID: 36282326.
    8. Kato D, Uchida H, Hinoki A, Sumida W, Shirota C, Makita S, Okamoto M, Takimoto A, Takada S, Nakagawa Y. IgG4-related disease of duodenal obstruction due to multiple ulcers in a 12-year-old girl. BMC Pediatr. 2023 Jul 25;23(1):376. doi: 10.1186/s12887-023-04190-z. PMID: 37491193; PMCID: PMC10369806.
    9. Nakagawa Y, Maeda T, Uchida H, Takada S, Hinoki A, Shirota C, Tainaka T, Sumida W, Makita S, Amano H, Takimoto A, Gohda Y. Case Report: Retropancreatic fascia hernia protruding into the thoracic cavity through a Bochdalek hernia. Front Pediatr. 2023 Jun 26;11:1149515. doi: 10.3389/fped.2023.1149515. PMID: 37435174; PMCID: PMC10331128.
    10. Takada S, Shirota C, Uchida H, Amano H, Hinoki A, Sumida W, Makita S, Okamoto M, Takimoto A, Yasui A, Nakagawa Y, Kato D, Guo Y, Tainaka T. Management of Congenital and Postoperative Chylothorax: Use of Thoracoscopic Lymphatic Leak Ligations with Intraoperative ICG Lymphangiography. J Pediatr Surg. 2023 Sep;58(9):1754-1761. doi: 10.1016/j.jpedsurg.2022.11.018. Epub 2022 Dec 5. PMID: 36609065.
    11. Takimoto A, Amano H, Sumida W, Shirota C, Yokota K, Makita S, Okamoto M, Ogata S, Takada S, Nakagawa Y, Kato D, Goda Y, Hinoki A, Uchida H. Laparoscopic Duodenal-Caudal Detachment Method: Early Experience of a Novel Technique for Malrotation with Volvulus in Neonates. J Laparoendosc Adv Surg Tech A. 2023 Feb;33(2):220-225. doi: 10.1089/lap.2022.0390. Epub 2022 Nov 16. PMID: 36383112.
    12. Takada S, Uchida H, Hinoki A, Shirota C, Sumida W, Tainaka T, Makita S, Takimoto A, Nakagawa Y, Maeda T. Variations of the hepatic artery and bile duct in patients with pancreaticobiliary maljunction: Impact on postoperative outcomes. J Hepatobiliary Pancreat Sci. 2023 Nov;30(11):1241-1248. doi: 10.1002/jhbp.1381. Epub 2023 Oct 25. PMID: 37876298.
    13. Nakagawa Y, Uchida H, Hinoki A, Tainaka T, Shirota C, Sumida W, Makita S, Yokota K, Amano H, Yasui A, Maeda T, Kato D, Gohda Y. Preoperative management comprising tube irrigation using a trans-anal indwelling tube for infants with hirschsprung disease can allow single-stage radical surgery. BMC Surg. 2023 Nov 1;23(1):333. doi: 10.1186/s12893-023-02232-y. PMID: 37915052; PMCID: PMC10621192.
    14. Maeda T, Liu J, Uchida H, Amano H, Shirota C, Tainaka T, Sumida W, Makita S, Takimoto A, Takada S, Nakagawa Y, Gouda A, Guo Y, Hinoki A. Robotic versus laparoscopic radical surgery for pediatric congenital biliary dilatation: a comparison of surgical outcomes of a single surgeon's initial experience. Pediatr Surg Int. 2023 Sep 3;39(1):261. doi: 10.1007/s00383-023-05548-1. PMID: 37660350.
    15. Nakagawa Y, Sumida W, Makita S, Uchida H, Hinoki A, Shirota C, Tainaka T, Yokota K, Amano H, Yasui A, Takimoto A, Kato D, Maeda T, Gohda Y. Case report: Laparoscopic gastrojejunostomy for duodenal atresia with situs inversus and preduodenal portal vein: a report of two cases. Front Pediatr. 2023 Jun 27;11:1220393. doi: 10.3389/fped.2023.1220393. PMID: 37441573; PMCID: PMC10333570.
    16. Nakagawa Y, Uchida H, Hinoki A, Shirota C, Sumida W, Makita S, Amano H, Masamune O, Takimoto A, Ogata S, Takada S, Kato D, Gohda Y, Guo Y. Rare case of a right Bochdalek hernia with retroperitoneal prolapse of organs into the thoracic cavity in infancy: A case report. Asian J Endosc Surg. 2023 Apr;16(2):284-288. doi: 10.1111/ases.13139. Epub 2022 Nov 6. PMID: 36336788.
    17. Takimoto A, Sumida W, Shirota C, Makita S, Okamoto M, Ogata S, Takada S, Nakagawa Y, Kato D, Goda Y, Hinoki A, Uchida H. Retroperitoneoscopic resection of a large paraganglioma surrounded by the right diaphragmatic crus on the dorsal side of the inferior vena cava: A pediatric case report. Asian J Endosc Surg. 2023 Jan;16(1):131-134. doi: 10.1111/ases.13119. Epub 2022 Aug 18. PMID: 35981721.
    18. Nakagawa Y, Uchida H, Hinoki A, Shirota C, Sumida W, Makita S, Masamune O, Ogata S, Takimoto A, Takada S, Kato D, Gohda Y. Laparoscopic closure of Roux limb perforation during double-balloon endoscopic retrograde cholangiography with laparoscopy-assisted endoscopic hepatolithectomy 30 years after congenital biliary dilatation radical surgery: A case report. Asian J Endosc Surg. 2023 Jan;16(1):118-122. doi: 10.1111/ases.13116. Epub 2022 Aug 11. PMID: 35957492.
    19. Gohda Y, Uchida H, Hinoki A, Shirota C, Sumida W, Makita S, Okamoto M, Ogata S, Takimoto A, Takada S, Nakagawa Y, Kato D, Guo Y. Laparoscopic internal intestinal drainage of bile lakes in a patient with recurrence of jaundice after laparoscopic revision of Kasai portoenterostomy for biliary atresia: A case report. Asian J Endosc Surg. 2023 Apr;16(2):275-278. doi: 10.1111/ases.13133. Epub 2022 Sep 30. PMID: 36180047.
    20. Guo Y, Hinoki A, Deie K, Tainaka T, Sumida W, Makita S, Okamoto M, Takimoto A, Yasui A, Takada S, Nakagawa Y, Kato D, Maeda T, Amano H, Kawashima H, Uchida H, Shirota C. Anastomotic time was associated with postoperative complications: a cumulative sum analysis of thoracoscopic repair of tracheoesophageal fistula in a single surgeon's experience. Surg Today. 2023 Dec;53(12):1363-1371. doi: 10.1007/s00595-023-02687-9. Epub 2023 Apr 23. PMID: 37087700.
    21. Nakagawa Y, Uchida H, Hinoki A, Shirota C, Sumida W, Makita S, Yokota K, Amano H, Yasui A, Kato D, Gohda Y, Maeda T. Refractory esophageal anastomotic stricture after esophageal atresia surgery improved with retrograde balloon dilatation through gastrostomy followed by laparoscopic fundoplication: a case report. Surg Case Rep. 2023 Sep 22;9(1):169. doi: 10.1186/s40792-023-01754-0. PMID: 37737524; PMCID: PMC10516835.
    22. Nakagawa Y, Uchida H, Hinoki A, Shirota C, Tainaka T, Sumida W, Makita S, Yasui A, Takimoto A, Guo Y. Laparoscopic bile duct plasty for hilar bile duct stenosis (HBDS) in patients with congenital biliary dilatation: Diagnosis of HBDS by preoperative MRCP and laparoscopic strategy to relieve HBDS. J Hepatobiliary Pancreat Sci. 2023 Apr;30(4):473-481. doi: 10.1002/jhbp.1235. Epub 2022 Sep 11. PMID: 36047878.
    23. Nakagawa Y, Yokota K, Uchida H, Hinoki A, Shirota C, Tainaka T, Sumida W, Makita S, Amano H, Takimoto A, Ogata S, Takada S, Maeda T, Gohda Y. Laparoscopic restorative proctocolectomy with ileal-J-pouch anal canal anastomosis without diverting ileostomy for total colonic and extensive aganglionosis is safe and feasible with combined Lugol's iodine staining technique and indocyanine green fluorescence angiography. Front Pediatr. 2023 Jan 6;10:1090336. doi: 10.3389/fped.2022.1090336. PMID: 36683800; PMCID: PMC9853408.
    24. Nakagawa Y, Uchida H, Shirota C, Tainaka T, Sumida W, Makita S, Amano H, Takimoto A, Ogata S, Takada S, Maeda T, Gohda Y, Guo Y, Hinoki A. Preoperative Contrast Examinations Help Determine the Appropriate Cervical Approach for Congenital Gross Type C Esophageal Atresia: A Report of Two Cases. Am J Case Rep. 2023 Jun 13;24:e938723. doi: 10.12659/AJCR.938723. PMID: 37309107; PMCID: PMC10274229.
  • 2022年
    1. Miyagishima M, Hamada M, Hirayama Y, Muramatsu H, Tainaka T, Shirota C, Hinoki A, Imaizumi T, Nakatochi M, Kamei M, Nishikawa E, Kawashima N, Narita A, Nishio N, Kojima S, Takahashi Y. Risk factors for unplanned removal of central venous catheters in hospitalized children with hematological and oncological disorders. Int J Hematol. 2022 Aug;116(2):288-294. doi: 10.1007/s12185-022-03346-4. Epub 2022 Jun 21. PMID: 35727532.
    2. Takeshita T, Yoshida M, Takei Y, Ouchi A, Hinoki A, Uchida H, Kobayashi T. Development of wearable multi-lead ECG measurement device using cubic flocked electrode. Sci Rep. 2022 Nov 11;12(1):19308. doi: 10.1038/s41598-022-24043-6. PMID: 36369527; PMCID: PMC9652328.
    3. Makita S, Amano H, Kawashima H, Hinoki A, Shirota C, Tainaka T, Sumida W, Yokota K, Okamoto M, Takimoto A, Yasui A, Nakagawa Y, Uchida H. Utility of endoscopic retrograde cholangiopancreatography in management of pediatric pancreaticobiliary disease. BMC Pediatr. 2022 Mar 14;22(1):134. doi: 10.1186/s12887-022-03207-3. PMID: 35287648; PMCID: PMC8919614.
    4. Shirota C, Tainaka T, Sumida W, Yokota K, Makita S, Amano H, Okamoto M, Takimoto A, Yasui A, Nakagawa Y, Hinoki A, Uchida H. Single-incision laparoscopic percutaneous extraperitoneal closure (SILPEC) for inguinal hernia with prolapsed ovary. Surg Endosc. 2022 Jun;36(6):4328-4332. doi: 10.1007/s00464-021-08777-4. Epub 2021 Oct 19. PMID: 34668067.
    5. Nakagawa Y, Makita S, Uchida H, Hinoki A, Shirota C, Sumida W, Amano H, Okamoto M, Takimoto A, Ogata S, Takada S, Kato D, Gohda Y, Guo Y. Refractory tracheoesophageal fistula treated using multi-stage surgery: A case report. Front Pediatr. 2022 Dec 21;10:1053154. doi: 10.3389/fped.2022.1053154. PMID: 36619516; PMCID: PMC9811173.
    6. Taniguchi R, Muramatsu H, Okuno Y, Yoshida T, Wakamatsu M, Hamada M, Shirota C, Sumida W, Hinoki A, Tainaka T, Gotoh Y, Tsuzuki T, Tanaka Y, Kojima S, Uchida H, Takahashi Y. A patient with very early onset FH-deficient renal cell carcinoma diagnosed at age seven. Fam Cancer. 2022 Jul;21(3):337-341. doi: 10.1007/s10689-021-00268-8. Epub 2021 Jun 22. PMID: 34156580.
    7. Shirota C, Hinoki A, Togawa T, Ito S, Sumida W, Makita S, Amano H, Takimoto A, Takada S, Okamoto M, Nakagawa Y, Kato D, Uchida H. Intraoperative indocyanine green fluorescence cholangiography can rule out biliary atresia: A preliminary report. Front Pediatr. 2022 Nov 4;10:1005879. doi: 10.3389/fped.2022.1005879. PMID: 36405823; PMCID: PMC9671931.
    8. Tainaka T, Shirota C, Sumida W, Yokota K, Makita S, Amano H, Okamoto M, Takimoto A, Kano Y, Yasui A, Nakagawa Y, Hinoki A, Uchida H. Laparoscopic definitive surgery for choledochal cyst is performed safely and effectively in infants. J Minim Access Surg. 2022 Jul-Sep;18(3):372-377. doi: 10.4103/jmas.JMAS_98_21. PMID: 35708382; PMCID: PMC9306120.
    9. Shirota C, Hinoki A, Tainaka T, Sumida W, Kinoshita F, Yokota K, Makita S, Amano H, Nakagawa Y, Uchida H. Laparoscopic Kasai portoenterostomy can be a standard surgical procedure for treatment of biliary atresia. World J Gastrointest Surg. 2022 Jan 27;14(1):56-63. doi: 10.4240/wjgs.v14.i1.56. PMID: 35126863; PMCID: PMC8790325.
    10. Deie K, Nakagawa Y, Uchida H, Hinoki A, Shirota C, Tainaka T, Sumida W, Yokota K, Makita S, Fujiogi M, Okamoto M, Takimoto A, Yasui A, Takada S, Maeda T. Evaluation of minimally invasive surgical skills training: comparing a neonatal esophageal atresia/tracheoesophageal fistula model with a dry box. Surg Endosc. 2022 Aug;36(8):6035-6048. doi: 10.1007/s00464-022-09185-y. Epub 2022 Mar 21. PMID: 35312850.
    11. Nakagawa Y, Uchida H, Amano H, Hinoki A, Tainaka T, Shirota C, Sumida W, Yokota K, Makita S, Okamoto M, Takimoto A, Yasui A, Takada S, Kato D. Patients with gastric volvulus recurrence have high incidence of wandering spleen requiring laparoscopic gastropexy and splenopexy. Pediatr Surg Int. 2022 Jun;38(6):875-881. doi: 10.1007/s00383-022-05125-y. Epub 2022 Apr 7. PMID: 35391540.
    12. Nakagawa Y, Hinoki A, Amano H, Uchida H, Shirota C, Tainaka T, Sumida W, Yokota K, Makita S, Okamoto M, Takimoto A, Yasui A, Takada S, Kato D. Circumumbilical incision for neonatal abdominal surgery: additional skin incision when there is difficulty in manipulating the intestine. Nagoya J Med Sci. 2022 Nov;84(4):716-722. doi: 10.18999/nagjms.84.4.716. PMID: 36544608; PMCID: PMC9748330.
    13. Sumida W, Tainaka T, Shirota C, Yokota K, Makita S, Okamoto M, Takimoto A, Yasui A, Takada S, Nakagawa Y, Kato D, Yokoyama S, Ishizu Y, Amano H, Guo Y, Hinoki A, Uchida H. Biochemical markers to predict the development of gastrointestinal bleeding and esophageal varices after portoenterostomy in biliary atresia. Pediatr Surg Int. 2022 Dec;38(12):1799-1805. doi: 10.1007/s00383-022-05243-7. Epub 2022 Sep 17. PMID: 36114864.
    14. Yokoyama S, Ishizu Y, Honda T, Imai N, Ito T, Yamamoto K, Hinoki A, Sumida W, Shirota C, Tainaka T, Makita S, Yokota K, Uchida H, Ishigami M. Endoscopic injection sclerotherapy with polidocanol for cardiac varices in children and adolescents. Arch Pediatr. 2023 Feb;30(2):109-112. doi: 10.1016/j.arcped.2022.11.016. Epub 2022 Dec 9. PMID: 36509625.
    15. Nakagawa Y, Uchida H, Amano H, Hinoki A, Shirota C, Sumida W, Yokota K, Makita S, Okamoto M, Takimoto A, Yasui A, Takada S, Maeda T. Safety and feasibility of primary radical surgery for meconium peritonitis considering patients' general condition and perioperative findings. Nagoya J Med Sci. 2022 Feb;84(1):148-154. doi: 10.18999/nagjms.84.1.148. PMID: 35392019; PMCID: PMC8971046.
    16. Yasui A, Hinoki A, Amano H, Shirota C, Tainaka T, Sumida W, Yokota K, Makita S, Okamoto M, Takimoto A, Nakagawa Y, Uchida H. Adding a spur valve to laparoscopic portoenterostomy for patients with biliary atresia can achieve a high jaundice clearance rate and lower the number of episodes of cholangitis. Pediatr Surg Int. 2022 Dec;38(12):1881-1885. doi: 10.1007/s00383-022-05230-y. Epub 2022 Sep 14. PMID: 36104601.
    17. Kato D, Uchida H, Amano H, Hinoki A, Shirota C, Sumida W, Yokota K, Makita S, Okamoto M, Takimoto A, Yasui A, Takada S, Nakagawa Y. Laparoscopic revision of Kasai portoenterostomy after initial laparoscopic portoenterostomy in patients with biliary atresia: a limited but positive effect on native liver survival. Pediatr Surg Int. 2022 Dec;38(12):1821-1827. doi: 10.1007/s00383-022-05235-7. Epub 2022 Sep 14. PMID: 36104599.
    18. Nakagawa Y, Makita S, Uchida H, Hinoki A, Shirota C, Sumida W, Amano H, Okamoto M, Takimoto A, Yasui A, Ogata S, Takada S, Kato D, Gohda Y, Yaohui G. Case report: A giant bilateral inguinal hernia requiring artificial mesh and multi-stage surgery in infancy; hernioplasty with silo placement to prevent acute compartment syndrome. Front Pediatr. 2022 Nov 10;10:1030934. doi: 10.3389/fped.2022.1030934. PMID: 36440330; PMCID: PMC9684311.
    19. Tainaka T, Shirota C, Hinoki A, Sumida W, Yokota K, Makita S, Amano H, Tanaka Y, Uchida H. Laparoscopic definitive surgery for congenital biliary dilatation with aggressive hilar bile ductoplasty and complete resection of the intrapancreatic bile duct in pediatric patients is safe and effective, comparable to open surgery. Surg Endosc. 2022 Oct;36(10):7352-7359. doi: 10.1007/s00464-022-09132-x. Epub 2022 Feb 28. PMID: 35226163.
    20. Yasui A, Hinoki A, Amano H, Shirota C, Tainaka T, Sumida W, Yokota K, Makita S, Okamoto M, Takimoto A, Nakagawa Y, Uchida H. Thoracoscopic posterior tracheopexy during primary esophageal atresia repair ameliorate tracheomalacia in neonates: a single-center retrospective comparative cohort study. BMC Surg. 2022 Jul 25;22(1):285. doi: 10.1186/s12893-022-01738-1. PMID: 35879691; PMCID: PMC9310495.
    21. Takimoto A, Amano H, Shirota C, Sumida W, Makita S, Okamoto M, Ogata S, Takada S, Nakagawa Y, Kato D, Gohda Y, Hinoki A, Uchida H. Hemi-circumferential mucosal resection and anastomosis procedure for rectal prolapse following anorectoplasty for anorectal malformations. Surg Today. 2023 May;53(5):628-632. doi: 10.1007/s00595-022-02611-7. Epub 2022 Oct 25. PMID: 36282326.
    22. Nakagawa Y, Sumida W, Amano H, Uchida H, Hinoki A, Shirota C, Makita S, Okamoto M, Ogata S, Takimoto A, Takada S, Kato D, Gohda Y. Preoperative imaging contributes to pathologically complete resection of the urachal remnant by determining an appropriate surgical approach without unnecessary and excessive surgical invasion: a retrospective study. BMC Urol. 2022 Dec 19;22(1):207. doi: 10.1186/s12894-022-01153-x. PMID: 36536334; PMCID: PMC9764728.
    23. Nakagawa Y, Uchida H, Hinoki A, Shirota C, Sumida W, Makita S, Amano H, Okamoto M, Takimoto A, Ogata S, Takada S, Kato D, Gohda Y. Combined negative pressure wound therapy with irrigation and dwell time and artificial dermis prevents infection and promotes granulation formation in a ruptured giant omphalocele: a case report. BMC Pediatr. 2022 Nov 26;22(1):680. doi: 10.1186/s12887-022-03755-8. PMID: 36435753; PMCID: PMC9701383.
    24. Takada S, Shirota C, Uchida H, Amano H, Hinoki A, Sumida W, Makita S, Okamoto M, Takimoto A, Yasui A, Nakagawa Y, Kato D, Guo Y, Tainaka T. Management of Congenital and Postoperative Chylothorax: Use of Thoracoscopic Lymphatic Leak Ligations with Intraoperative ICG Lymphangiography. J Pediatr Surg. 2023 Sep;58(9):1754-1761. doi: 10.1016/j.jpedsurg.2022.11.018. Epub 2022 Dec 5. PMID: 36609065.
    25. Takimoto A, Amano H, Sumida W, Shirota C, Yokota K, Makita S, Okamoto M, Ogata S, Takada S, Nakagawa Y, Kato D, Goda Y, Hinoki A, Uchida H. Laparoscopic Duodenal-Caudal Detachment Method: Early Experience of a Novel Technique for Malrotation with Volvulus in Neonates. J Laparoendosc Adv Surg Tech A. 2023 Feb;33(2):220-225. doi: 10.1089/lap.2022.0390. Epub 2022 Nov 16. PMID: 36383112.
    26. Nakagawa Y, Uchida H, Hinoki A, Shirota C, Sumida W, Makita S, Amano H, Masamune O, Takimoto A, Ogata S, Takada S, Kato D, Gohda Y, Guo Y. Rare case of a right Bochdalek hernia with retroperitoneal prolapse of organs into the thoracic cavity in infancy: A case report. Asian J Endosc Surg. 2023 Apr;16(2):284-288. doi: 10.1111/ases.13139. Epub 2022 Nov 6. PMID: 36336788.
    27. Gohda Y, Uchida H, Hinoki A, Shirota C, Sumida W, Makita S, Okamoto M, Ogata S, Takimoto A, Takada S, Nakagawa Y, Kato D, Guo Y. Laparoscopic internal intestinal drainage of bile lakes in a patient with recurrence of jaundice after laparoscopic revision of Kasai portoenterostomy for biliary atresia: A case report. Asian J Endosc Surg. 2023 Apr;16(2):275-278. doi: 10.1111/ases.13133. Epub 2022 Sep 30. PMID: 36180047.
    28. Nakagawa Y, Uchida H, Hinoki A, Shirota C, Sumida W, Makita S, Masamune O, Ogata S, Takimoto A, Takada S, Kato D, Gohda Y. Laparoscopic closure of Roux limb perforation during double-balloon endoscopic retrograde cholangiography with laparoscopy-assisted endoscopic hepatolithectomy 30 years after congenital biliary dilatation radical surgery: A case report. Asian J Endosc Surg. 2023 Jan;16(1):118-122. doi: 10.1111/ases.13116. Epub 2022 Aug 11. PMID: 35957492.
    29. Takimoto A, Sumida W, Shirota C, Makita S, Okamoto M, Ogata S, Takada S, Nakagawa Y, Kato D, Goda Y, Hinoki A, Uchida H. Retroperitoneoscopic resection of a large paraganglioma surrounded by the right diaphragmatic crus on the dorsal side of the inferior vena cava: A pediatric case report. Asian J Endosc Surg. 2023 Jan;16(1):131-134. doi: 10.1111/ases.13119. Epub 2022 Aug 18. PMID: 35981721.
    30. Nakagawa Y, Yokota K, Uchida H, Hinoki A, Shirota C, Tainaka T, Sumida W, Makita S, Amano H, Takimoto A, Ogata S, Takada S, Maeda T, Gohda Y. Laparoscopic restorative proctocolectomy with ileal-J-pouch anal canal anastomosis without diverting ileostomy for total colonic and extensive aganglionosis is safe and feasible with combined Lugol's iodine staining technique and indocyanine green fluorescence angiography. Front Pediatr. 2023 Jan 6;10:1090336. doi: 10.3389/fped.2022.1090336. PMID: 36683800; PMCID: PMC9853408.
    31. Nakagawa Y, Uchida H, Hinoki A, Shirota C, Tainaka T, Sumida W, Makita S, Yasui A, Takimoto A, Guo Y. Laparoscopic bile duct plasty for hilar bile duct stenosis (HBDS) in patients with congenital biliary dilatation: Diagnosis of HBDS by preoperative MRCP and laparoscopic strategy to relieve HBDS. J Hepatobiliary Pancreat Sci. 2023 Apr;30(4):473-481. doi: 10.1002/jhbp.1235. Epub 2022 Sep 11. PMID: 36047878.
  • 2021年
    1. Yokota K, Uchida H, Sakairi M, Abe M, Tanaka Y, Tainaka T, Shirota C, Sumida W, Oshima K, Makita S, Amano H, Hinoki A. Identification of novel neuroblastoma biomarkers in urine samples. Sci Rep. 2021 Feb 18;11(1):4055. doi: 10.1038/s41598-021-83619-w. PMID: 33603049; PMCID: PMC7892837.
    2. Shirota C, Tainaka T, Sumida W, Yokota K, Makita S, Amano H, Okamoto M, Takimoto A, Yasui A, Nakagawa Y, Hinoki A, Uchida H. Single-incision laparoscopic percutaneous extraperitoneal closure (SILPEC) for inguinal hernia with prolapsed ovary. Surg Endosc. 2022 Jun;36(6):4328-4332. doi: 10.1007/s00464-021-08777-4. Epub 2021 Oct 19. PMID: 34668067.
    3. Yokota K, Hinoki A, Hiramatsu K, Amano H, Kawamura M, Kuwatsuka Y, Tainaka T, Shirota C, Sumida W, Makita S, Okamoto M, Takimoto A, Yasui A, Nakagawa Y, Uchida H, Kawakita M. Urinary N1,N12-diacetylspermine as a biomarker for pediatric cancer: a case-control study. Pediatr Surg Int. 2021 Dec;37(12):1659-1665. doi: 10.1007/s00383-021-04987-y. Epub 2021 Aug 28. PMID: 34453590.
    4. Taniguchi R, Muramatsu H, Okuno Y, Yoshida T, Wakamatsu M, Hamada M, Shirota C, Sumida W, Hinoki A, Tainaka T, Gotoh Y, Tsuzuki T, Tanaka Y, Kojima S, Uchida H, Takahashi Y. A patient with very early onset FH-deficient renal cell carcinoma diagnosed at age seven. Fam Cancer. 2022 Jul;21(3):337-341. doi: 10.1007/s10689-021-00268-8. Epub 2021 Jun 22. PMID: 34156580.
    5. Yamaguchi S, Hinoki A, Tsubouchi K, Amano H, Tajima A, Uchida H. Usefulness of web search queries for early detection of diseases in infants. Nagoya J Med Sci. 2021 Feb;83(1):107-111. doi: 10.18999/nagjms.83.1.107. PMID: 33727742; PMCID: PMC7938097.
    6. Yokoyama S, Ishizu Y, Ishigami M, Honda T, Kuzuya T, Ito T, Hinoki A, Sumida W, Shirota C, Tainaka T, Makita S, Yokota K, Uchida H, Fujishiro M. Factors associated with bleeding after endoscopic variceal ligation in children. Pediatr Int. 2021 Oct;63(10):1223-1229. doi: 10.1111/ped.14614. Epub 2021 Aug 20. PMID: 33464654.
    7. Tanaka Y, Tainaka T, Hinoki A, Shirota C, Sumida W, Yokota K, Oshima K, Makita S, Amano H, Takimoto A, Kano Y, Uchida H. Risk factors and outcomes of bile leak after laparoscopic surgery for congenital biliary dilatation. Pediatr Surg Int. 2021 Feb;37(2):235-240. doi: 10.1007/s00383-020-04791-0. Epub 2021 Jan 3. PMID: 33392697.
    8. Okamoto M, Amano H, Uchida H, Hinoki A, Tainaka T, Shirota C, Sumida W, Yokota K, Makita S, Takimoto A, Yasui A, Nakagawa Y. Clinical characteristics and outcomes of the right congenital diaphragmatic hernia compared to the left: a 10-year single-center experience. Pediatr Surg Int. 2021 Dec;37(12):1675-1681. doi: 10.1007/s00383-021-04999-8. Epub 2021 Aug 26. PMID: 34436672.
    9. Shirota C, Tainaka T, Sumida W, Yokota K, Makita S, Takimoto A, Amano H, Hinoki A, Ono Y, Uchida H. Thoracoscopic surgery for congenital lung cysts: an attempt to limit pulmonary resection in cases of lesions involving multiple lobes. Pediatr Surg Int. 2021 Feb;37(2):213-221. doi: 10.1007/s00383-020-04793-y. Epub 2021 Jan 1. PMID: 33386446.
    10. Sumida W, Tainaka T, Shirota C, Yokota K, Makita S, Takimoto A, Yasui A, Okamoto M, Nakagawa Y, Hinoki A, Uchida H. An imaging study on tracheomalacia in infants with esophageal atresia: the degree of tracheal compression by the brachiocephalic artery is a good indicator for therapeutic intervention. Pediatr Surg Int. 2021 Dec;37(12):1719-1724. doi: 10.1007/s00383-021-04985-0. Epub 2021 Aug 28. PMID: 34453588.
    11. Tainaka T, Hinoki A, Tanaka Y, Shirota C, Sumida W, Yokota K, Makita S, Oshima K, Amano H, Takimoto A, Kano Y, Uchida H. ＜Editors' Choice＞ Long-term outcomes of the partial splenectomy for hypersplenism after portoenterostomy of patients with biliary atresia. Nagoya J Med Sci. 2021 Nov;83(4):765-771. doi: 10.18999/nagjms.83.4.765. PMID: 34916720; PMCID: PMC8648531.
    12. Takimoto A, Sumida W, Amano H, Shirota C, Tainaka T, Yokota K, Makita S, Yasui A, Kanou Y, Hinoki A, Uchida H. Postoperative intestinal obstruction in patients with biliary atresia impedes biliary excretion and results in subsequent liver transplantation. Pediatr Surg Int. 2021 Feb;37(2):229-234. doi: 10.1007/s00383-020-04807-9. Epub 2021 Jan 3. Erratum in: Pediatr Surg Int. 2021 Jun;37(6):835. PMID: 33388958; PMCID: PMC7847427.
    13. Shirota C, Kawashima H, Tainaka T, Sumida W, Yokota K, Makita S, Amano H, Takimoto A, Hinoki A, Uchida H. Double-balloon endoscopic retrograde cholangiography can make a reliable diagnosis and good prognosis for postoperative complications of congenital biliary dilatation. Sci Rep. 2021 May 26;11(1):11052. doi: 10.1038/s41598-021-90550-7. PMID: 34040119; PMCID: PMC8155203.
    14. Amano H, Shirota C, Tainaka T, Sumida W, Yokota K, Makita S, Takimoto A, Tanaka Y, Hinoki A, Kawashima H, Uchida H. Late postoperative complications of congenital biliary dilatation in pediatric patients: a single-center experience of managing complications for over 20 years. Surg Today. 2021 Sep;51(9):1488-1495. doi: 10.1007/s00595-021-02238-0. Epub 2021 Mar 10. PMID: 33689035.
    15. Takimoto A, Sumida W, Amano H, Shirota C, Tainaka T, Yokota K, Makita S, Yasui A, Kanou Y, Hinoki A, Uchida H. Correction to: Postoperative intestinal obstruction in patients with biliary atresia impedes biliary excretion and results in subsequent liver transplantation. Pediatr Surg Int. 2021 Jun;37(6):835. doi: 10.1007/s00383-021-04873-7. Erratum for: Pediatr Surg Int. 2021 Feb;37(2):229-234. PMID: 33725159; PMCID: PMC8329822.
  • 2020年
    1. Amano H, Miyake K, Hinoki A, Yokota K, Kinoshita F, Nakazawa A, Tanaka Y, Seto Y, Uchida H. Novel zinc alloys for biodegradable surgical staples. World J Clin Cases. 2020 Feb 6;8(3):504-516. doi: 10.12998/wjcc.v8.i3.504. PMID: 32110659; PMCID: PMC7031837.
    2. Shirota C, Murase N, Tanaka Y, Ogura Y, Nakatochi M, Kamei H, Kurata N, Hinoki A, Tainaka T, Sumida W, Yokota K, Makita S, Oshima K, Uchida H. Laparoscopic Kasai portoenterostomy is advantageous over open Kasai portoenterostomy in subsequent liver transplantation. Surg Endosc. 2020 Aug;34(8):3375-3381. doi: 10.1007/s00464-019-07108-y. Epub 2019 Sep 4. PMID: 31485932.
    3. Tanaka T, Amano H, Tanaka Y, Takahashi Y, Tajiri T, Tainaka T, Shirota C, Sumida W, Yokota K, Makita S, Tani Y, Hinoki A, Uchida H. Safe diagnostic management of malignant mediastinal tumors in the presence of respiratory distress: a 10-year experience. BMC Pediatr. 2020 Jun 10;20(1):292. doi: 10.1186/s12887-020-02183-w. PMID: 32522190; PMCID: PMC7285522.
    4. Yokota K, Amano H, Kudo T, Yamamura T, Tanaka Y, Tainaka T, Shirota C, Sumida W, Makita S, Takimoto A, Nakamura M, Fujishiro M, Hinoki A, Uchida H. A novel Lugol's iodine staining technique to visualize the upper margin of the surgical anal canal intraoperatively for Hirschsprung disease: a case series. BMC Surg. 2020 Dec 4;20(1):317. doi: 10.1186/s12893-020-00986-3. PMID: 33276766; PMCID: PMC7718680.

研究キーワード

尿中代謝物、小児がん、希少性・難治性がん、小児外科

名古屋大学大学院医学系研究科病態外科学専攻小児外科

小児外科学 独自ホームページ