研究業績

Recruit

2025年

1.英文原著

Koujiya E, Takeshita Y, Yakabe M, Mizokami F, Umegaki H, Takeya Y. Impact of Multiple Low-Anticholinergic Drugs on Older Inpatients: Insights From the J-HAC Study. Geriatr Gerontol Int. 2026 Jan;26(1):e70273. doi: 10.1111/ggi.70273. Epub 2025 Nov 30. PMID: 41319653; PMCID: PMC12809374.

Shimokawa H, Akishita M, Asada T, Katayama S, Hattori Y, Yakushiji Y, Taki Y, Murai H, Boku Y, Tsujimoto M, Umegaki H, Ogawa T, Matsumoto S, Ono K, Imon Y, Tsunemi T, Iwata A, Hanajima R, Hisahara S, Uehara T, Ishiguro T, Nakaoku Y, Ishii K, Ishiki A, Nagai Y, Teramukai S, Ihara M, Fukushima M. Baseline characteristics of patients with early Alzheimer's disease enrolled in the pivotal trial of low-intensity pulsed ultrasound (LIPUS-AD). J Alzheimers Dis Rep. 2025 Dec 29;9:25424823251407541. doi: 10.1177/25424823251407541. PMID: 41477670; PMCID: PMC12748502.

Huang Z, Piao L, Meng X, Inoue A, Hitomi K, Umegaki H, Kuzuya M, Cheng XW. Correction: Human umbilical cord-derived mesenchymal stromal cell exosomes ameliorate aging-associated skeletal muscle atrophy and dysfunction in SAMP10 mice. Stem Cell Res Ther. 2025 Dec 18;16(1):679. doi: 10.1186/s13287-025-04868-4. Erratum for: Stem Cell Res Ther. 2025 Jul 28;16(1):410. doi: 10.1186/s13287-025-04477-1. PMID: 41413605; PMCID: PMC12713291.

Yoshiko A, Nakashima H, Nagae M, Sakai T, Matsui Y, Umegaki H. Skeletal muscle thickness and echo intensity may reflect the risk of malnutrition and physical dysfunction in acutely hospitalized older patients. Eur Geriatr Med. 2025 Dec 17. doi: 10.1007/s41999-025-01384-9. Epub ahead of print. PMID: 41405745.
Matsui Y, Fujisawa C, Minakami M, Yamada Y, Watanabe K, Nakashima H, Komiya H, Umegaki H. The decline in cognitive function with age and its changes over time in cognitively normal older adults. Eur Geriatr Med. 2025 Dec 6. doi: 10.1007/s41999-025-01377-8. Epub ahead of print. PMID: 41351653.

Kuzuya M, Kanno Y, Arai H, Nishiguchi S, Iijima K, Umegaki H, Satake S, Sato S, Shinmura K, Sugimoto K, Nishikawa H, Mori K, Yoshimura Y, Wakabayashi H, Inoue A, Inoue T, Uedono H, Uno C, Okamura M, Ogawa S, Ogawa M, Kadoya H, Kinoshita K, Kou K, Sato Y, Shojima K, Suzuki N, Son BK, Tsuda A, Nagata K, Nagano F, Fujita Y, Maeda A, Matsui M, Matsumoto A, Miyazaki K, Mori T, Yasuoka M, Yamazaki H, Yamamoto T, Li J, Lyu W. Guidelines for Nutritional Management of Sarcopenia and Frailty 2025. Guest Editor: Masafumi Kuzuya. This publication has been supported by The Japan Geriatrics Society and National Center for Geriatrics and Gerontology (NCGG) (Japan). Geriatr Gerontol Int. 2025 Dec;25 Suppl 2:5-53. doi: 10.1111/ggi.70275. PMID: 41524691.

Miyahara S, Maeda K, Satake S, Nagae M, Nakashima H, Takeya Y, Umeda-Kameyama Y, Umegaki H. Prognostic value of low estimated appendicular skeletal muscle mass in hospitalized older adults: A multicenter prospective observational study. Arch Gerontol Geriatr. 2025 Nov;138:105958. doi: 10.1016/j.archger.2025.105958. Epub 2025 Jul 21. PMID: 40716250.

Yamada Y, Nakashima H, Nagae M, Watanabe K, Fujisawa C, Komiya H, Tajima T, Sakai T, Satake S, Umegaki H. Association of Serum Creatinine-Cystatin C Ratio With Hospital-Associated Complications and Post-Discharge Mortality. Geriatr Gerontol Int. 2025 Nov;25(11):1564-1570. doi: 10.1111/ggi.70206. Epub 2025 Oct 1. PMID: 41031546; PMCID: PMC12584936.

Nagae M, Umegaki H, Nakashima H, Nishiuchi T. HALP and FI-Lab Scores in Hospitalized Older Adults: A Retrospective Comparative Study of Adverse Outcomes. J Gen Intern Med. 2025 Oct 7. doi: 10.1007/s11606-025-09889-6. Epub ahead of print. PMID: 41055685.

Huang Z, Piao L, Meng X, Inoue A, Hitomi K, Umegaki H, Kuzuya M, Cheng XW. Human umbilical cord-derived mesenchymal stromal cell exosomes ameliorate aging-associated skeletal muscle atrophy and dysfunction in SAMP10 mice. Stem Cell Res Ther. 2025 Jul 28;16(1):410. doi: 10.1186/s13287-025-04477-1. PMID: 40722197; PMCID: PMC12306081.

Nakashima H, Imaizumi T, Komiya H, Morohashi A, Watanabe K, Fujisawa C, Yamada Y, Nagao Y, Umegaki H. Laboratory frailty index improves prediction of in-hospital falls among older adults. Aging Clin Exp Res. 2025 Jun 5;37(1):179. doi: 10.1007/s40520-025-03090-9. PMID: 40471425; PMCID: PMC12141401.
Tajima T, Nakashima H, Nagae M, Komiya H, Fujisawa C, Watanabe K, Yamada Y, Umegaki H. Pre-discharge energy intake and post-discharge mortality in acutely hospitalized older adults. Aging Clin Exp Res. 2025 May 26;37(1):170. doi: 10.1007/s40520-025-03076-7. PMID: 40418302; PMCID: PMC12106510.

Umegaki H. Frailty, multimorbidity, and polypharmacy: Proposal of the new concept of the geriatric triangle. Geriatr Gerontol Int. 2025 May;25(5):657-662. doi: 10.1111/ggi.70046. Epub 2025 Apr 14. PMID: 40229144; PMCID: PMC12055515.

Kitada T, Umegaki H, Akima H, Ishida K, Nakatochi M, Inoue A, Huang CH, Ando M, Onishi J, Kuzuya M. Effects of Weight-Bearing Resistance Training With Explosive Motions on the Rate of Force Development in Community-Dwelling Older Adults: A Randomized Controlled Trial. J Phys Act Health. 2025 Mar 4;22(6):706-715. doi: 10.1123/jpah.2024-0431. PMID: 40043717.

Komiya H, Suzuki Y, Watanabe K, Nagae M, Nakashima H, Fujisawa C, Miyahara S, Tajima T, Sakai T, Takeya Y, Kojima T, Umeda-Kameyama Y, Kawashima S, Umegaki H. Validation of the Japanese version of the Clinical Frailty Scale. Geriatr Gerontol Int. 2025 Mar;25(3):411-417. doi: 10.1111/ggi.15092. Epub 2025 Feb 2. PMID: 39895104; PMCID: PMC12216798.

Umegaki H, Satake S, Ishii S, Kojima T, Akasaka H, Ogawa S, Ebihara S, Tsubata Y, Akishita M. Chapter 2: Management of geriatric diseases and geriatric syndrome using comprehensive geriatric assessment (CGA): English translation of the Japanese CGA-based healthcare guidelines 2024. Geriatr Gerontol Int. 2025 Mar;25 Suppl 1:16-23. doi: 10.1111/ggi.15087. PMID: 40091155.

Shibasaki K, Ogawa S, Hosoi T, Ishii S, Mizukami K, Umegaki H, Mizokami F, Satake S, Akishita M. Chapter 1: Effectiveness of each element of the comprehensive geriatric assessment (CGA): English translation of the Japanese CGA-based healthcare guidelines 2024. Geriatr Gerontol Int. 2025 Mar;25 Suppl 1:9-15. doi: 10.1111/ggi.15086. PMID: 40091157.

Nagae M, Umegaki H, Komiya H, Watanabe K, Yamada Y. Factors associated with decline in activities of daily living in home-based medical care. Nagoya J Med Sci. 2025 Feb;87(1):173-177. doi: 10.18999/nagjms.87.1.173. PMID: 40255994; PMCID: PMC12003990.

Watanabe K, Nagae M, Miyahara S, Umegaki H. Dysphagia and quality of life in older adults receiving home-based medical care. Geriatr Gerontol Int. 2025 Feb;25(2):325-326. doi: 10.1111/ggi.15071. Epub 2025 Jan 13. PMID: 39805741; PMCID: PMC12216787.

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