Research Topics

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2020.02.05 Identification of characteristic chromosome structural abnormality in diffuse midline glioma, H3 K27M-mutant with whole-genome sequencing. ~ H3F3A mutant allele specific imbalance in an aggressive subtype of diffuse midline glioma, H3 K27M-mutant~
2020.02.05 Comprehensive analysis of a novel mouse model of the 22q11.2 deletion syndrome: A model with the most common 3.0-Mb deletion at the human 22q11.2 locus Key Points
2020.02.04 Blockade of EGFR improves responsiveness to PD1 blockade in EGFR-mutated non-small cell lung cancer
2020.01.31 Near Infrared Photoimmunotherapy Targeting DLL3 For Small Cell Lung Cancer
2020.01.29 Ovarian cancer-associated mesothelial cells induce acquired platinum-resistance in peritoneal metastasis via the FN1/Akt signaling pathway
2020.01.28 Elucidation of poor prognostic factors in acute myeloid leukemia - Expected to develop new treatment strategy and improve prognosis -
2020.01.08 Hypothalamic Contribution to Pituitary Functions is Recapitulated in vitro Using 3D-cultured Human iPS Cells
2019.12.23 Dual Microglia Effects on Blood Brain Barrier Permeability Induced by Systemic Inflammation
2019.12.04 Novel protein function could be the key to treatment of drug addiction and behavioral disorders
2019.11.22 The development of hepatocellular carcinoma can be inhibited by TFF1.
2019.11.22 Discovery of a simple, reliable and inexpensive method as an alternative to pathological examination to confirm the excised parathyroid gland! A feasible way to reduce the incidence of hypoparathyroidism after thyroid surgery
2019.11.19 Transgenic Archaerhodopsin-3 Expression in Hypocretin/Orexin Neurons Engenders Cellular Dysfunction and Features of Type 2 Narcolepsy
2019.11.06 SDR9C7 catalyzes critical dehydrogenation of acylceramides for skin barrier formation
2019.11.06 Dorsal-to-ventral cortical expansion is physically primed by ventral streaming of early embryonic preplate neurons
2019.10.24 iPS Cell Research Discovers Common Pathologies in Psychiatric Disorders Elucidation of the Pathogenesis of Bipolar Disorder and Schizophrenia May Find Application in Therapeutic Drug Development
2019.10.23 Protein kinase N promotes stress-induced cardiac dysfunction through phosphorylation of myocardin-related transcription factor A and disruption of its interaction with actin.
2019.10.18 Selective inhibition of low-affinity memory CD8+ T cells by corticosteroids
2019.10.02 The Discovery of an Oncometabolite Contributing to the Resistance to Nutrient Starvation
2019.09.20 REM sleep-active MCH neurons are involved in forgetting hippocampus-dependent memories
2019.09.20 Src inhibition attenuates polyglutamine-mediated neuromuscular degeneration in spinal and bulbar muscular atrophy