名古屋大学（静岡）

  1. Kawai S, Naito M, Morita E, Okada R, Hishida A, Wakai K, Hamajima N. GGT1 intronic A>G polymorphism affects setum concentration of γ-glutamyl transpeptidase among Japanese healthy adults. Ningen Dock International 2015; 2: 65-69.
  2. Suma S, Naito M, Wakai K, Sasakabe T, Hattori Y, Okada R, Kawai S, Hishida A, Morita E, Nakagawa H, Tamura T, Hamajima N. Effects of IL6 C-634G polymorphism on tooth loss and their interaction with smoking habits. Oral Dis 2015; 21: 807-813.
  3. Chiba T, Matsuo H, Nagamori S, Nakayama A, Kawamura Y, Shimizu S, Sakiyama M, Hosoyamada M, Kawai S, Okada R, Hamajima N, Kanai Y, Shinomiya N. Identification of a hypouricemia patient with SLC2A9 R380W, a pathogenic mutation for renal hypouricemia type 2. Nucleosides Nucleotides Nucleic Acids 2014; 33: 261-265.
  4. Matsuo H, Nakayama A, Sakiyama M, Chiba T, Shimizu S, Kawamura Y, Nakashima H, Nakamura T, Takada Y, Oikawa Y, Takada T, Nakaoka H, Abe J, Inoue H, Wakai K, Kawai S, Guang Y, Nakagawa H, Ito T, Niwa K, Yamamoto K, Sakurai Y, Suzuki H, Hosoya T, Ichida K, Shimizu T, Shinomiya N. ABCG2 dysfunction causes hyperuricemia due to both renal urate underexcretion and renal urate overload. Sci Rep 2014; 4: 3755.
  5. Nakayama A, Matsuo H, Nakaoka H, Nakamura T, Nakashima H, Takada Y, Oikawa Y, Takada T, Sakiyama M, Shimizu S, Kawamura Y, Chiba T, Abe J, Wakai K, Kawai S, Okada R, Tamura T, Shichijo Y, Akashi A, Suzuki H, Hosoya T, Sakurai Y, Ichida K, Shinomiya N. Common dysfunctional variants of ABCG2 have stronger impact on hyperuricemia progression than typical environmental risk factors. Sci Rep 2014; 4: 5227.
  6. Nakayama A, Matsuo H, Shimizu T, Takada Y, Nakamura T, Shimizu S, Chiba T, Sakiyama M, Naito M, Morita E, Ichida K, Shinomiya N. Common variants of a urate-associated gene LRP2 are not associated with gout susceptibility. Rheumatol Int 2014; 34: 473-476.
  7. Sakiyama M, Matsuo H, Chiba T, Nakayama A, Nakamura T, Shimizu S, Morita E, Fukuda N, Nakashima H, Sakurai Y, Ichida K, Shimizu T, Shinomiya N. Common variants of cGKII/PRKG2 are not associated with gout susceptibility. J Rheumatol 2014; 41: 1395-1397.
  8. Sakiyama M, Matsuo H, Shimizu S, Chiba T, Nakayama A, Takada Y, Nakamura T, Takada T, Morita E, Naito M, Wakai K, Inoue H, Tatsukawa S, Sato J, Shimono K, Makino T, Satoh T, Suzuki H, Kanai Y, Hamajima N, Sakurai Y, Ichida K, Shimizu T, Shinomiya N. A common variant of leucine-rich repeat-containing 16A (LRRC16A) gene is associated with gout susceptibility. Hum Cell 2014; 27: 1-4.
  9. Sakiyama M, Matsuo H, Shimizu S, Nakashima H, Nakayama A, Chiba T, Naito M, Takada T, Suzuki H, Hamajima N, Ichida K, Shimizu T, Shinomiya N. A common variant of organic anion transporter 4 (OAT4/SLC22A11) gene is associated with renal underexcretion type gout. Drug Metab Pharmacokinet 2014; 29: 208-210.
  10. Sakiyama M, Matsuo H, Takada Y, Nakamura T, Nakayama A, Takada T, Kitajiri S I, Wakai K, Suzuki H, Shinomiya N. Ethnic differences in ATP-binding cassette transporter, sub-family G, member 2 (ABCG2/BCRP): genotype combinations and estimated functions. Drug Metab Pharmacokinet 2014; 29: 490-492.
  11. Suma S, Naito M, Okada R, Kawai S, Yin G, Morita E, Wakai K, Matsuo H, Hamajima N. Associations between body mass index and serum uric acid levels in a Japanese population were significantly modified by LRP2 rs2544390. Nagoya J Med Sci 2014; 76: 333-339.
  12. Takada Y, Matsuo H, Nakayama A, Sakiyama M, Hishida A, Okada R, Sakurai Y, Shimizu T, Ichida K, Shinomiya N. Common variant of PDZK1, adaptor protein gene of urate transporters, is not associated with gout. J Rheumatol 2014; 41: 2330-2331.
  13. Higashibata T, Naito M, Mori A, Ozawa N, Furuta M, Tsuchiya R, Koyama E, Morita E, Kawai S, Okada R, Yin G, Wakai K, Hamajima N. DPP4 genetic variants influence baseline prostate-specific antigen levels: the J-MICC study. Nagoya J Med Sci 2013; 75: 73-80.
  14. Matsuo H, Ichida K, Takada T, Nakayama A, Nakashima H, Nakamura T, Kawamura Y, Takada Y, Yamamoto K, Inoue H, Oikawa Y, Naito M, Hishida A, Wakai K, Okada C, Shimizu S, Sakiyama M, Chiba T, Ogata H, Niwa K, Hosoyamada M, Mori A, Hamajima N, Suzuki H, Kanai Y, Sakurai Y, Hosoya T, Shimizu T, Shinomiya N. Common dysfunctional variants in ABCG2 are a major cause of early-onset gout. Sci Rep 2013; 3: 2014.
  15. Nakayama A, Matsuo H, Shimizu T, Ogata H, Takada Y, Nakashima H, Nakamura T, Shimizu S, Chiba T, Sakiyama M, Ushiyama C, Takada T, Inoue K, Kawai S, Hishida A, Wakai K, Hamajima N, Ichida K, Sakurai Y, Kato Y, Shimizu T, Shinomiya N. A common missense variant of monocarboxylate transporter 9 (MCT9/SLC16A9) gene is associated with renal overload gout, but not with all gout susceptibility. Hum Cell 2013; 26: 133-136.
  16. Hamajima N, Naito M, Okada R, Kawai S, Yin G, Morita E, Higashibata T, Tamura T, Nakagawa H, Matsuo H, Mori A, Wakai K. Significant interaction between LRP2 rs2544390 in intron 1 and alcoholdrinking for serum uric acid levels among a Japanese population. Gene 2012; 503: 131-136.
  17. Naito M, Asai Y, Mori A, Fukada Y, Kuwabara M, Katase S, Hishida A, Morita E, Kawai S, Okada R, Nishio K, Tamakoshi A, Wakai K, Hamajima N. Association of obesity and diabetes with serum prostate-specific antigen levels in Japanese males. Nagoya J Med Sci 2012; 74: 285-292.
  18. Nobata S, Hishida A, Naito M, Asai Y, Mori A, Kuwabara M, Katase S, Okada R, Morita E, Kawai S, Hamajima N, Wakai K. Association between KLK3 rs2735839 G/A polymorphism and serum PSA levels in Japanese men. Urol Int 2012; 89: 39-44.
  19. Okada R, Wakai K, Naito M, Morita E, Kawai S, Yin G, Ozawa N, Furuta M, Koyama E, Tsuchiya R, Kouno N, Hamajima N. Renal hyperfiltration in prediabetes confirmed by fasting plasma glucose and hemoglobin a1c. Ren Fail 2012; 34: 1084-1090.
  20. Hamajima N, Naito M, Hishida A, Okada R, Asai Y, Wakai K. Serum uric acid distribution according to SLC22A12 W258X genotype in a cross-sectional study of a general Japanese population. BMC Med Genet 2011; 12: 33.
  21. Hamajima N, Okada R, Kawai S, Hishida A, Morita E, Yin G, Wakai K, Matsuo H, Inoue H, Takada Y, Asai Y, Mori A, Naito M. Significant association of serum uric acid levels with SLC2A9 rs11722228 among a Japanese population. Mol Genet Metab 2011; 103: 378-382.
  22. Morita E, Naito M, Hishida A, Wakai K, Mori A, Asai Y, Okada R, Kawai S, Hamajima N. No association between the frequency of forest walking and blood pressure levels or the prevalence of hypertension in a cross-sectional study of a Japanese population. Environ Health Prev Med 2011; 16: 299-306.
  23. 森田えみ, 内藤真理子, 西尾和子, 石田喜子, 菱田朝陽, 若井建志, 浅井八多美, 浜島信之. 人間ドック受診者を対象とした静岡県中西部地区における森林散策頻度に関する大規模調査. 日本森林学会誌 2010; 92: 110-114.
  24. Asai Y, Naito M, Suzuki M, Tomoda A, Kuwabara M, Fukada Y, Okamoto A, Oishi S, Ikeda K, Nakamura T, Misu Y, Katase S, Tokumasu S, Nishio K, Ishida Y, Hishida A, Morita E, Kawai S, Okada R, Wakai K, Tamakoshi A, Hamajima N. Baseline data of Shizuoka area in the Japan Multi-Institutional Collaborative Cohort Study (J-MICC Study). Nagoya J Med Sci 2009; 71: 137-144.
  25. Matsuo H, Takada T, Ichida K, Nakamura T, Nakayama A, Ikebuchi Y, Ito K, Kusanagi Y, Chiba T, Tadokoro S, Takada Y, Oikawa Y, Ioue H, Suzuki K, Okada R, Nishiyama J, Domoto H, Watanabe S, Fujita M, Morimoto Y, Naito M, Nishio K, Hishida A, Wakai K, Asai Y, Niwa K, Kamakura K, Nonoyama S, Sakurai Y, Hosoya T, Kanai Y, Suzuki H, Hamajima N, Shinomiya N. Common defects of ABCG2, a high-capacity urate exporter, cause gout: a function-based genetic analysis in a Japanese population. Sci Transl Med 2009; 1: 5ra11.

J-MICC全体

  1. Koyama T, Matsui D, Kuriyama N, Ozaki E, Tanaka K, Oze I, Hamajima N, Wakai K, Okada R, Arisawa K, Mikami H, Shimatani K, Hirata A, Takashima N, Suzuki S, Nagata C, Kubo M, Tanaka H. Genetic variants of SLC17A1 are associated with cholesterol homeostasis and hyperhomocysteinemia in Japanese men. Sci Rep in press.
  2. Yamaguchi M, Uemura H, Arisawa K, Katsuura-Kamano S, Hamajima N, Hishida A, Suma S, Oze I, Nakamura K, Takashima N, Suzuki S, Ibusuki R, Mikami H, Ohnaka K, Kuriyama N, Kubo M, Tanaka H, The Japan Multi-institutional Collaborative Cohort (J-MICC) Study Group. Association between brain-muscle-ARNT-like protein-2 (BMAL2) gene polymorphism and type 2 diabetes mellitus in obese Japanese individuals: A cross-sectional analysis of the Japan Multi-Institutional Collaborative Cohort Study. Diabetes Res Clin Pract in press.
  3. Hosono S, Ito H, Oze I, Higaki Y, Morita E, Takashima N, Suzuki S, Shimatani K, Mikami H, Ohnaka K, Ozaki E, Katsuura-Kamano S, Kubo M, Nagata C, Naito M, Hamajima N, Tanaka H, Japan Multi-Institutional Collaborative Cohort Study Group. Polymorphisms in CYP19A1, HSD17B1 and HSD17B2 genes and serum sex hormone level among postmenopausal Japanese women. Maturitas 2015; in press.
  4. Sugimoto Y, Wakai K, Nakagawa H, Suma S, Sasakabe T, Sakamoto T, Takashima N, Suzuki S, Ogawa S, Ohnaka K, Kuriyama N, Arisawa K, Mikami H, Kubo M, Hosono S, Hamajima N, Tanaka H, for the J-MICC Study Group. Associations between polymorphisms of interleukin-6 and related cytokine genes and serum liver damage markers: a cross-sectional study in the Japan Multi-Institutional Collaborative Cohort (J-MICC) Study. Gene 2015; 557: 158-162.
  5. Uemura H, Katsuura-Kamano S, Yamaguchi M, Arisawa K, Hamajima N, Hishida A, Kawai S, Oze I, Shinchi K, Takashima N, Suzuki S, Nakahata N, Mikami H, Ohnaka K, Kuriyama N, Kubo M, Tanaka H, Japan Multi-institutional Collaborative Cohort Study Group. A variant of the CLOCK gene and related haplotypes are associated with the prevalence of type 2 diabetes in the Japanese population. J Diabetes 2015; in press.
  6. Hara M, Nakamura K, Nanri H, Nishida Y, Hishida A, Kawai S, Hamajima N, Kita Y, Suzuki S, Mantjoro E M, Ohnaka K, Uemura H, Matsui D, Oze I, Mikami H, Kubo M, Tanaka H, Japan Multi-Institutional Collaborative Cohort Study Group. Associations between hOGG1 Ser326Cys polymorphism and increased body mass index and fasting glucose level in the Japanese general population. J Epidemiol 2014; 24: 379-384.
  7. Hishida A, Takashima N, Turin T C, Kawai S, Wakai K, Hamajima N, Hosono S, Nishida Y, Suzuki S, Nakahata N, Mikami H, Ohnaka K, Matsui D, Katsuura-Kamano S, Kubo M, Tanaka H, Kita Y. GCK, GCKR polymorphisms and risk of chronic kidney disease in Japanese individuals: data from the J-MICC Study. J Nephrol 2014; 27: 143-149.
  8. Hishida A, Wakai K, Naito M, Suma S, Sasakabe T, Hamajima N, Hosono S, Horita M, Turin T C, Suzuki S, Kairupan T S, Mikami H, Ohnaka K, Watanabe I, Uemura H, Kubo M, Tanaka H. Polymorphisms of genes involved in lipid metabolism and risk of chronic kidney disease in Japanese - cross-sectional data from the J-MICC study. Lipids Health Dis 2014; 13: 162.
  9. Katsuura-Kamano S, Uemura H, Arisawa K, Yamaguchi M, Hamajima N, Wakai K, Okada R, Suzuki S, Taguchi N, Kita Y, Ohnaka K, Kairupan T S, Matsui D, Oze I, Mikami H, Kubo M, Tanaka H. A polymorphism near MC4R gene (rs17782313) is associated with serum triglyceride levels in the general Japanese population: the J-MICC Study. Endocrine 2014; 47: 81-89.
  10. Hishida A, Okada R, Naito M, Morita E, Wakai K, Hamajima N, Hosono S, Nanri H, Chowdhury Turin T, Suzuki S, Kuwabara K, Mikami H, Budhathoki S, Watanabe I, Arisawa K, Kubo M, Tanaka H. Polymorphisms in genes encoding antioxidant enzymes (SOD2, CAT, GPx, TXNRD, SEPP1, SEP15 and SELS) and risk of chronic kidney disease in Japanese - cross-sectional data from the J-MICC study. J Clin Biochem Nutr 2013; 53: 15-20.
  11. Hishida A, Okada R, Yin G, Naito M, Wakai K, Hosono S, Nakamura K, Chowdhury Turin T, Suzuki S, Eiji N, Mikami H, Otonari J, Kuriyama N, Katsuura S, Kubo M, Tanaka H, Hamajima N. MTHFR, MTR and MTRR polymorphisms and risk of chronic kidney disease in Japanese: cross-sectional data from the J-MICC Study. Int Urol Nephrol 2013; 45: 1613-1620.
  12. Hishida A, Wakai K, Naito M, Tamura T, Kawai S, Hamajima N, Oze I, Imaizumi T, Turin T C, Suzuki S, Kheradmand M, Mikami H, Ohnaka K, Watanabe Y, Arisawa K, Kubo M, Tanaka H. Polymorphisms in PPAR genes (PPARD, PPARG and PPARGC1A) and risk of chronic kidney disease in Japanese: cross-sectional data from the J-MICC Study. PPAR Res 2013; 2013: Article ID: 980471.
  13. Hishida A, Wakai K, Okada R, Morita E, Hamajima N, Hosono S, Higaki Y, Chowdhury Turin T, Suzuki S, Motahareh K, Mikami H, Tashiro N, Watanabe I, Katsuura S, Kubo M, Tanaka H, Naito M. Significant interaction between RETN -420 G/G genotype and lower BMI on decreased risk of Type 2 DM in Japanese - the J-MICC Study [Rapid Communication]. Endocr J 2013; 60: 237-243.
  14. Nakamura A, Niimura H, Kuwabara K, Takezaki T, Morita E, Wakai K, Hamajima N, Nishida Y, Turin T C, Suzuki S, Ohnaka K, Uemura H, Ozaki E, Hosono S, Mikami H, Kubo M, Tanaka H. Gene-gene combination effect and interactions among ABCA1, APOA1, SR-B1, and CETP polymorphisms for serum high-density lipoprotein-cholesterol in the Japanese population. PLoS One 2013; 8: e82046.
  15. Wakai K, Matsuo K, Matsuda F, Yamada R, Takahashi M, Kawaguchi T, Yatabe Y, Ito H, Hosono S, Tajima K, Naito M, Morita E, Yin G, Sakamoto T, Takashima N, Suzuki S, Nakahata N, Mikami H, Ohnaka K, Watanabe Y, Arisawa K, Kubo M, Hamajima N, Tanaka H for the J-MICC Study Group. Genome-wide association study of the genetic factors related to confectionery intake: potential roles of the ADIPOQ gene. Obesity. 2013; 21: 2413-9.
  16. Hara M, Higaki Y, Taguchi N, Shinchi K, Morita E, Naito M, Hamajima N, Takashima N, Suzuki S, Nakamura A, Ohnaka K, Uemura H, Nishida H, Hosono S, Mikami H, Kubo M, Tanaka H, on behalf of the Japan Multi-Institutional Collaborative Cohort (J-MICC) Study Group. Effect of the PPARG2 Pro12Ala polymorphism and clinical risk factors for diabetes mellitus on HbA1c in the Japanese general population. J Epidemiol 2012; 22: 523-531.
  17. Higashibata T, Hamajima N, Naito M, Kawai S, Yin G, Suzuki S, Kita Y, Niimura H, Imaizumi T, Ohnaka K, Arisawa K, Shigeta M, Ito H, Mikami H, Kubo M, Tanaka H, Wakai K. eNOS genotype modifies the effect of leisure-time physical activity on serum triglyceride levels in a Japanese population. Lipids Health Dis 2012; 11: 150.
  18. Hishida A, Morita E, Naito M, Okada R, Wakai K, Matsuo K, Nakamura K, Takashima N, Suzuki S, Takezaki T, Mikami H, Ohnaka K, Watanabe Y, Uemura H, Kubo M, Tanaka H, Hamajima N. Associations of apolipoprotein A5 (APOA5), glucokinase (GCK) and glucokinase regulatory protein (GCKR) polymorphisms and lifestyle factors with the risk of dyslipidemia and dysglycemia in Japanese - a cross-sectional data from the J-MICC Study. Endocr J 2012; 59: 589-599.
  19. Hiyoshi M, Uemura H, Arisawa K, Nakamoto M, Hishida A, Okada R, Matsuo K, Kita Y, Niimura H, Kuriyama N, Nanri H, Ohnaka K, Suzuki S, Mikami H, Kubo M, Tanaka H, Hamajima N, for the J-MICC Study Group. Association between the catechol-O-methyltransferase (rs4680: Val158Met) polymorphism and serum alanine aminotransferase activity. Gene 2012; 496: 97-102.
  20. Nishiyama T, Kishino H, Suzuki S, Ando R, Niimura H, Uemura H, Horita M, Ohnaka K, Kuriyama N, Mikami H, Takashima N, Mastuo K, Guang Y, Wakai K, Hamajima N, Tanaka H, for J-MICC Study Group. Detailed analysis of Japanese population substructure with a focus on the southwest islands of Japan. PLoS One 2012; 7: e35000.
  21. Okada R, Kawai S, Naito M, Hishida A, Hamajima N, Shinchi K, Kita Y, Suzuki S, Mantjoro M, Toyomura K, Arisawa K, Kuriyama N, Hosono S, Mikami H, Kubo M, Tanaka H, Wakai K, the Japan Multi-Institutional Collaborative Cohort (J-MICC) Study Group. Matrix metalloproteinase-9 gene polymorphisms and chronic kidney disease. Am J Nephrol 2012; 36: 444-450.
  22. Okada R, Wakai K, Naito M, Morita E, Kawai S, Hamajima N, Hara M, Takashima N, Suzuki S, Takezaki T, Ohnaka K, Arisawa K, Hirohata H, Matsuo K, Mikami H, Kubo M, Tanaka H. Pro/anti-inflammatory cytokine gene polymorphisms and chronic kidney disease: a cross-sectional study. BMC Nephrol 2012; 13: 2.
  23. Uemura H, Hiyoshi M, Arisawa K, Yamaguchi M, Naito M, Kawai S, Hamajima N, Matsuo K, Taguchi N, Takashima N, Suzuki S, Hirasada K, Mikami H, Ohnaka K, Yoshikawa A, Kubo M, Tanaka H. Gene variants in PPARD and PPARGC1A are associated with timing of natural menopause in the general Japanese population. Maturitas 2012; 71: 369-375.
  24. Wakai K, Hamajima N, Okada R, Naito M, Morita E, Hishida A, Kawai S, Nishio K, Yin G, Asai Y, Matsuo K, Hosono S, Ito H, Watanabe M, Kawase T, Suzuki T, Tajima K, Tanaka K, Higaki Y, Hara M, Imaizumi T, Taguchi N, Nakamura K, Nanri H, Sakamoto T, Horita M, Shinchi K, Kita Y, Turin T C, Rumana N, Matsui K, Miura K, Ueshima H, Takashima N, Nakamura Y, Suzuki S, Ando R, Hosono A, Imaeda N, Shibata K, Goto C, Hattori N, Fukatsu M, Yamada T, Tokudome S, Takezaki T, Niimura H, Hirasada K, Nakamura A, Tatebo M, Ogawa S, Tsunematsu N, Chiba S, Mikami H, Kono S, Ohnaka K, Takayanagi R, Watanabe Y, Ozaki E, Shigeta M, Kuriyama N, Yoshikawa A, Matsui D, Watanabe I, Inoue K, Ozasa K, Mitani S, Arisawa K, Uemura H, Hiyoshi M, Takami H, Yamaguchi M, Nakamoto M, Takeda H, Kubo M, Tanaka H, for the J-MICC Study Group. Profile of participants and genotype distributions of 108 polymorphisms in a cross-sectional study of associations of genotypes with lifestyle and clinical factors: a project in the Japan Multi-Institutional Collaborative Cohort (J-MICC) Study. J Epidemiol 2011; 21: 223-235.
  25. Naito M, Eguchi H, Okada R, Ishida Y, Nishio K, Hishida A, Wakai K, Tamakoshi A, Hamajima N, for the J-MICC Study Group. Controls for monitoring the deterioration of stored blood samples in the Japan Multi-Institutional Collaborative Cohort Study (J-MICC Study). Nagoya J Med Sci 2008; 70: 107-115.
  26. Hamajima N, ; The J-MICC Study Group. The Japan Multi-institutional Collaborative Cohort Study (J-MICC Study) to detect gene-environment interactions for cancer. Asian Pac J Cancer Prev 2007; 8: 317-323.
  27. 浜島信之. 疫学研究のためのDNA検体保存：J-MICC研究の場合. 医学のあゆみ 2007; 220: 824-827.