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Center for Maternal - Neonatal Care Director：KOTANI, Tomomi (Clinical Professor)

Comprehensive support for the health of mothers and babies using advanced medicine

The Center performs obstetric medical care, reproductive medicine, intensive care for premature babies and newborn infants with complications including high risk childbirth.


Medical Care System

10 specialized doctors in the division of Reproduction and Perinatology and 14 specialized doctors in the division of Neonatology provide medical care. Even at night and on holidays, specialized doctors are assigned to the respective departments, who perform emergent childbirth delivery procedures and operations, handle emergent hospital admission, and monitor severe newborn infants.

Target Disease

The Center targets high risk pregnancy (pregnancy induced hypertension, pregnancy complicated by maternal disorders, placenta praevia, fetal disorders, etc.), infertility (including treatment for endometriosis, endoscopic surgery for uterine myoma, and fertility preservation through ovarian/oocyte cryopreservation), premature/low birth weight infants, critically ill infants (neonatal asphyxia, newborn infants with surgical disease complications, etc.).

Strong Fields

Fetal abnormality, placenta praevia accreta, total assisted reproductive techniques such as in vitro fertilization, microinsemination, monitoring of severe newborn infants needing advanced medical technology such as extracorporeal membrane oxygenation or hypothermia.

Clinical Results

Division of Reproduction and Perinatology

Recorded the following numbers of clinical cases in 2022: childbirth delivery (433 cases including 239 cases of caesarean operation) ; maternal transport (74 cases); fetus with congenital diseases (46 cases); in vitro fertilization (85 oocyte retrieval cycles), and embryo transfer (113 periods).

Division of Neonatology

Neonatal intensive care unit (NICU) hospital admission (333 cases); extremely low birth weight infant (18 cases); congenital diaphragmatic hernia (9 cases), and esophagial atresia (7 cases)(2022).

Advanced Medicine and Research

Division of Reproduction and Perinatology

Research on clinical conditions of preterm birth, hypertensive disordes of pregnancy placenta previa accreta, predicting severity of fetus' diaphragmatic hernia, ovarian tissue culture and cryopreservation.

Division of Neonatology

Research on regenerative medicine using stem cells for perinatal brain damage, chronic lung diseases and fetal growth restriction.Especially for the patients with hypoxic ischemic encephalopathy, an investigator-initiated clinical trial (The Evaluation of Safety and Tolerability of CL2020 in Neonatal Hypoxic Ischemic Encephalopathy Patients with Therapeutic Hypothermia in the Dose Escalation Clinical Trial; SHIELD Trial) has been completed.