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Top > 研究室紹介 > 脳神経病態制御学 > 精神医学

脳神経病態制御学精神医学

研究室概要

患者さんやご家族のニーズを考慮し、「日々の臨床的な疑問の解決」を進めるとともに、「病因や病態の解明を行い、その知見に基づいた診断法や治療法・予防法の開発」を目指すことが当講座の基本的な方針です。この目標を達成するためには、臨床研究と基礎研究が互いに連携しながら進められることが非常に重要です。
当講座では、統合失調症、うつ病、双極症、認知症、自閉スペクトラム症など、多岐にわたる精神障害に関する診断・治療法や病因・病態について、bio-psycho-social（生物・心理・社会的）な観点から包括的に研究を行っています。

研究プロジェクト

ゲノム　

  • ゲノム研究チームでは、さまざまなゲノム解析手法を用いた精神疾患の病態生理研究や薬理ゲノム学的研究を行っております。具体的には、全ゲノム関連解析や全ゲノムシークエンス解析を行い、精神疾患の新規診断法や治療反応予測法の開発、さらにはそれらの結果を元とした臨床研究や、基礎研究者と連携した病因・病態解明研究を実施しております。

  • 精神疾患を対象に、T2T（Telomere-to-Telomere）ロングリードシークエンス技術を用いてゲノム全域のバリアント検出を実施しています。従来解読困難だった領域も含め、疾患リスクに関わる遺伝的バリアントを包括的に解析しています。

精神療法　

  • 精神力動的精神医学とリエゾン精神医学を実践しています。がん患者や臓器移植患者の精神医学的疾患合併症について、抑うつ・不安に関連する心理社会的因子を検討し、早期発見と介入を目指しています。また、歯科領域の慢性疼痛患者を対象に、心理社会的評価を通じてストレス関連疾患の病態解明、治療法の開発に取り組みます。

臨床薬理・疫学　

  • 各種向精神薬の有効性、安全性、適正使用に関する臨床研究・疫学研究を行っています。臨床試験のみならず、リアルワールドデータを活用した研究など、臨床的な視点を重視した、新たなエビデンスの創出を目指しています。

  • 脳波、筋電図、睡眠、精神状態などの生体情報を基に疾患マーカーを探索し、進歩したウェアラブルデバイスの検証を通じて、臨床や在宅検査の可能性を探求しています。

神経病理/老年精神医学　

  • 名古屋ブレインバンクコンソーシアムを構築し、「精神症状の病理学的背景の解明」を目標として、統合失調症から神経変性疾患まで幅広いヒト脳組織解析を実施しています。世界的にも希少な精神科ブレインバンクは、病態解明に不可欠です。臨床研究では、認知症前駆期の精神症状に着目し、老年期発症精神疾患における神経画像などの診断バイオマーカーの検索やレビー小体型認知症の早期診断に注力しています

児　童　

  • 児童グループでは、神経発達症の遺伝学的研究、臨床研究を行うとともに、精神科および小児科を基盤とするサブスペシャルティである児童精神科（子どものこころの臨床領域）研修に関する研究を行っています。また、モンゴル国における児童精神科医養成プログラムの開発、運営にも協力しています。

画　像　

  • 主にMRIを用いて、精神疾患の病態解明や、診断補助・治療の効果判定・予後の予測などを目標とし研究を行っています。また、脳の構造や機能と認知機能、眼球運動などの臨床データとの関連も検討しています。

精神病理

  • 精神疾患全般や社会的ひきこもりを含む疾患周縁の精神病理と精神療法に関する研究を行い、記述的症例報告を通じてclinical case conferenceを実施しています。また、精神疾患の治療におけるガイドラインの普及に関する研究も行っています。

妊産婦　

  • 妊産婦は特にうつ病になりやすく、その影響は心身の健康や育児に及びます。遺伝要因と環境要因を検討するため、エピゲノム解析やAI解析を用いた前向きゲノムコホート研究を行い、妊産婦のうつ病との関係を明らかにすることを目指しています。

基　礎　

  • 発症リスクバリアントに基づく精神疾患モデル細胞・動物を活用し、精神疾患の創薬研究を行っています。また、精神疾患患者由来のiPS細胞を用いて、病態の解明と治療法の開発を目指しています。

教員

構成員名役職所属
池田 匡志 教授 大学院医学系研究科 総合医学専攻
尾崎 紀夫 特任教授 大学院医学系研究科 精神疾患病態解明学 糖鎖生命コア研究所 細胞・個体制御部門
藤城 弘樹 特任教授 大学院医学系研究科 精神医療学寄附講座
木村 宏之 准教授 大学院医学系研究科 総合医学専攻
岩本 邦弘 准教授 大学院医学系研究科 総合医学専攻
Branko Aleksic 特任准教授 大学院医学系研究科 名古屋大学・アデレード大学国際連携総合医学専攻
久島 周 病院講師 医学部附属病院 ゲノム医療センター
木村 大樹 講師 大学院医学系研究科 総合医学専攻
鳥井 洋太 講師 医学部附属病院 精神科
山本 真江里 講師 医学部附属病院 精神科
加藤 秀一 特任講師 大学院医学系研究科 精神医療学寄附講座
小笠原 一能 病院助教 医学部附属病院 卒後臨床研修・キャリア形成支援センター
立花 昌子 助教 医学部附属病院 精神科
名和 佳弘 助教 医学部附属病院 親と子どもの心療科
岩田 邦幸 助教 医学部附属病院 精神科
荒深 周生 病院助教 医学部附属病院 化学療法部
竹田 和弘 病院助教 医学部附属病院 精神科
林 優 特任助教 大学院医学系研究科 障害児（者）医療学寄附講座
森 大輔 特任准教授 脳とこころの研究センター 研究開発部門
有岡 祐子 特任講師 医学部附属病院 先端医療・臨床研究支援センター
宮田 聖子 特任講師 大学院医学系研究科 精神医療学寄附講座
奥村 啓樹 特任助教 大学院医学系研究科

研究実績

  • 2024年
    1. Arafuka S, Fujishiro H, Torii Y, Sekiguchi H, Habuchi C, Miwa A, Yoshida M, Iritani S, Iwasaki Y, Ikeda M and Ozaki N. Neuropathological substrate of incident dementia in older patients with schizophrenia: A clinicopathological study. Psychiatry Clin Neurosci 2024; 78: 29-40. 20230929. DOI: 10.1111/pcn.13597.
    2. Arafuka S, Torii Y, Fujishiro H, Sekiguchi H, Miwa A, Habuchi C, Sasada K, Yoshida M, Iritani S, Iwasaki Y and Ikeda M. Premorbid autistic traits in phenocopy syndrome of behavioral variant frontotemporal dementia: An autopsy revealing primary age-related tauopathy. Asian J Psychiatr 2025; 103: 104314. 20241118. DOI: 10.1016/j.ajp.2024.104314.
    3. Ashizawa T, Saito T, Okochi T, Ninomiya K, Ito K, Aoki R, Ikeda M and Iwata N. Association of plasma arachidonic acid levels with a bipolar disorder and the effects of a fads gene variant. Transl Psychiatry 2024; 14: 435. 20241014. DOI: 10.1038/s41398-024-03141-1.
    4. Ebina T, Iwamoto K and Ikeda M. Brexpiprazole-related tardive dystonia in a young patient with schizophrenia: A case report. Psychiatry Clin Neurosci 2024; 78: 334-335. 20240226. DOI: 10.1111/pcn.13653.
    5. Furukawa S, Arafuka S, Kato H, Ogi T, Ozaki N, Ikeda M and Kushima I. Treatment-resistant schizophrenia with 22q11.2 deletion and additional genetic defects. Neuropsychopharmacol Rep 2024; 44: 847-851. 20240827. DOI: 10.1002/npr2.12477.
    6. Furukawa S, Kushima I, Kato H, Kimura H, Nawa Y, Aleksic B, Banno M, Yamamoto M, Uematsu M, Nagasaki Y, Ogi T, Ozaki N and Ikeda M. Whole-genome sequencing analysis of japanese autism spectrum disorder trios. Psychiatry Clin Neurosci 2025; 79: 87-97. 20241128. DOI: 10.1111/pcn.13767.
    7. Hatanaka M, Hara K, Ohba C, Suzuki M, Ogura A, Kawabata K, Ito Y, Tada T, Fujita N, Mori D, Maesawa S, Kato K and Katsuno M. Combined quantitative analysis of the nigro-striata system in multiple system atrophy and parkinson's disease. J Neurol Sci 2025; 468: 123331. 20241126. DOI: 10.1016/j.jns.2024.123331.
    8. Hayashi Y, Okumura H, Arioka Y, Kushima I, Mori D, Lo T, Otgonbayar G, Kato H, Nawa Y, Kimura H, Aleksic B and Ozaki N. Analysis of human neuronal cells carrying astn2 deletion associated with psychiatric disorders. Transl Psychiatry 2024; 14: 236. 20240603. DOI: 10.1038/s41398-024-02962-4.
    9. Hori A, Su X, Sagasaki S, Saito R, Suijo K, Miyata S, Hasegawa D, Mizuno M and Hotta N. Sleep deprivation elevates resting and exercise blood pressures and augments pressor response at exercise onset. Med Sci Sports Exerc 2024 20241230. DOI: 10.1249/mss.0000000000003640.
    10. Inada T, Tanabe Y, Fukaya Y, Ogasawara K and Yamamoto N. Severity of antipsychotic-induced cervical dystonia assessed by the algorithm-based rating system. J Clin Psychiatry 2024; 85 20240415. DOI: 10.4088/JCP.23m14929.
    11. Ishikawa M, Yamamoto Y, Wulaer B, Kunisawa K, Fujigaki H, Ando T, Kimura H, Kushima I, Arioka Y, Torii Y, Mouri A, Ozaki N, Nabeshima T and Saito K. Indoleamine 2,3-dioxygenase 2 deficiency associates with autism-like behavior via dopaminergic neuronal dysfunction. Febs j 2024; 291: 945-964. 20240102. DOI: 10.1111/febs.17019.
    12. Iwamoto K, Nakabayashi T, Yamaguchi A, Konishi Y, Saji M, Yoshimura R, Kanemoto K, Aoki H, Ando M and Ozaki N. Effects of frequently prescribed antiseizure medications on motor vehicle driving performance: Narrative review based on a tiered approach for the assessment of clinically meaningful driving impairment in the ministry of health, labour, and welfare guideline. Neuropsychopharmacol Rep 2024; 44: 682-687. 20241104. DOI: 10.1002/npr2.12469.
    13. Kato T, Ogasawara K, Motomura K, Kato M, Tanaka T, Takaesu Y, Nio S, Kishi T, So M, Nemoto K, Suzuki E, Watanabe K and Matsuo K. Practice guidelines for bipolar disorder by the jsmd (japanese society of mood disorders). Psychiatry Clin Neurosci 2024; 78: 633-645. 20240828. DOI: 10.1111/pcn.13724.
    14. Kobayashi R, Iwata-Endo K and Fujishiro H. Clinical presentations and diagnostic application of proposed biomarkers in psychiatric-onset prodromal dementia with lewy bodies. Psychogeriatrics 2024; 24: 1004-1022. 20240604. DOI: 10.1111/psyg.13147.
    15. Koromina M, Ravi A, Panagiotaropoulou G, Schilder BM, Humphrey J, Braun A, Bidgeli T, Chatzinakos C, Coombes B, Kim J, Liu X, Terao C, KS OC, Adams M, Rolf A, Alda M, Alfredsson L, Andlauer TFM, Andreassen OA, Antoniou A, Baune BT, Bengesser S, Biernacka J, Boehnke M, Bosch R, Cairns MJ, Carr VJ, Casas M, Catts S, Cichon S, Corvin A, Craddock N, Dafnas K, Dalkner N, Dannlowski U, Degenhardt F, Florio AD, Dikeos D, Fellendorf FT, Ferentinos P, Forstner AJ, Forty L, Frye M, Fullerton JM, Gawlik M, Gizer IR, Gordon-Smith K, Green MJ, Grigoroiu-Serbanescu M, Guzman-Parra J, Hahn T, Henskens F, Hillert J, Jablensky AV, Jones L, Jones I, Jonsson L, Kelsoe JR, Kircher T, Kirov G, Kittel-Schneider S, Kogevinas M, Landén M, Leboyer M, Lenger M, Lissowska J, Lochner C, Loughland C, MacIntyre D, Martin NG, Maratou E, Mathews CA, Mayoral F, McElroy SL, McGregor NW, McIntosh A, McQuillin A, Michie P, Mitchell PB, Moutsatsou P, Mowry B, Müller-Myhsok B, Myers RM, Nenadić I, Nievergelt C, Nöthen MM, Nurnberger J, M OD, O'Donovan C, Ophoff RA, Owen MJ, Pantelis C, Pato C, Pato MT, Patrinos GP, Pawlak JM, Perlis RH, Porichi E, Posthuma D, Ramos-Quiroga JA, Reif A, Reininghaus EZ, Ribasés M, Rietschel M, Schall U, Schofield PR, Schulze TG, Scott L, Scott RJ, Serretti A, Weickert CS, Smoller JW, Artigas MS, Stein DJ, Streit F, Toma C, Tooney P, Vawter MP, Vieta E, Vincent JB, Waldman ID, Weickert T, Witt SH, Hong KS, Ikeda M, Iwata N, Świątkowska B, Won HH, Edenberg HJ, Ripke S, Raj T, Coleman JRI and Mullins N. Fine-mapping genomic loci refines bipolar disorder risk genes. medRxiv 2024 20240917. DOI: 10.1101/2024.02.12.24302716.
    16. Koyama S, Liu X, Koike Y, Hikino K, Koido M, Li W, Akaki K, Tomizuka K, Ito S, Otomo N, Suetsugu H, Yoshino S, Akiyama M, Saito K, Ishikawa Y, Benner C, Natarajan P, Ellinor PT, Mushiroda T, Horikoshi M, Ikeda M, Iwata N, Matsuda K, Niida S, Ozaki K, Momozawa Y, Ikegawa S, Takeuchi O, Ito K and Terao C. Population-specific putative causal variants shape quantitative traits. Nat Genet 2024; 56: 2027-2035. 20241003. DOI: 10.1038/s41588-024-01913-5.
    17. Kushima I, Nakatochi M and Ozaki N. Copy number variations and human well-being: Integrating psychiatric, physical, and socioeconomic perspectives. Biol Psychiatry 2024 20241204. DOI: 10.1016/j.biopsych.2024.11.019.
    18. Lo T, Kushima I, Kimura H, Aleksic B, Okada T, Kato H, Inada T, Nawa Y, Torii Y, Yamamoto M, Kimura R, Funabiki Y, Kosaka H, Numata S, Kasai K, Sasaki T, Yokoyama S, Munesue T, Hashimoto R, Yasuda Y, Fujimoto M, Usami M, Itokawa M, Arai M, Ohi K, Someya T, Watanabe Y, Egawa J, Takahashi T, Suzuki M, Yamasue H, Iwata N, Ikeda M and Ozaki N. Association between copy number variations in parkin (prkn) and schizophrenia and autism spectrum disorder: A case-control study. Neuropsychopharmacol Rep 2024; 44: 42-50. 20231101. DOI: 10.1002/npr2.12370.
    19. Miura K, Yoshida M, Morita K, Fujimoto M, Yasuda Y, Yamamori H, Takahashi J, Miyata S, Okazaki K, Matsumoto J, Toyomaki A, Makinodan M, Hashimoto N, Onitsuka T, Kasai K, Ozaki N and Hashimoto R. Gaze behaviors during free viewing revealed differences in visual salience processing across four major psychiatric disorders: A mega-analysis study of 1012 individuals. Mol Psychiatry 2025; 30: 1594-1600. 20241011. DOI: 10.1038/s41380-024-02773-5.
    20. Miyake N, Tsurusaki Y, Fukai R, Kushima I, Okamoto N, Ohashi K, Nakamura K, Hashimoto R, Hiraki Y, Son S, Kato M, Sakai Y, Osaka H, Deguchi K, Matsuishi T, Takeshita S, Fattal-Valevski A, Ekhilevitch N, Tohyama J, Yap P, Keng WT, Kobayashi H, Takubo K, Okada T, Saitoh S, Yasuda Y, Murai T, Nakamura K, Ohga S, Matsumoto A, Inoue K, Saikusa T, Hershkovitz T, Kobayashi Y, Morikawa M, Ito A, Hara T, Uno Y, Seiwa C, Ishizuka K, Shirahata E, Fujita A, Koshimizu E, Miyatake S, Takata A, Mizuguchi T, Ozaki N and Matsumoto N. Molecular diagnosis of 405 individuals with autism spectrum disorder. Eur J Hum Genet 2024; 32: 1551-1558. 20230327. DOI: 10.1038/s41431-023-01335-7.
    21. Miyata S, Iwamoto K, Okada I, Fujimoto A, Kogo Y, Mori D, Amano M, Matsuyama N, Nishida K, Ando M, Taoka T, Naganawa S and Ozaki N. Assessing the real-world, long-term impact of lemborexant on sleep quality in a home-based clinical study. Nat Sci Sleep 2024; 16: 291-303. 20240319. DOI: 10.2147/nss.S448871.
    22. Mori D, Ikeda R, Sawahata M, Yamaguchi S, Kodama A, Hirao T, Arioka Y, Okumura H, Inami C, Suzuki T, Hayashi Y, Kato H, Nawa Y, Miyata S, Kimura H, Kushima I, Aleksic B, Mizoguchi H, Nagai T, Nakazawa T, Hashimoto R, Kaibuchi K, Kume K, Yamada K and Ozaki N. Phenotypes for general behavior, activity, and body temperature in 3q29 deletion model mice. Transl Psychiatry 2024; 14: 138. 20240307. DOI: 10.1038/s41398-023-02679-w.
    23. Mori D, Inami C, Ikeda R, Sawahata M, Urata S, Yamaguchi ST, Kobayashi Y, Fujita K, Arioka Y, Okumura H, Kushima I, Kodama A, Suzuki T, Hirao T, Yoshimi A, Sobue A, Ito T, Noda Y, Mizoguchi H, Nagai T, Kaibuchi K, Okabe S, Nishiguchi K, Kume K, Yamada K and Ozaki N. Mice with deficiency in pcdh15, a gene associated with bipolar disorders, exhibit significantly elevated diurnal amplitudes of locomotion and body temperature. Transl Psychiatry 2024; 14: 216. 20240528. DOI: 10.1038/s41398-024-02952-6.
    24. Morikawa F, Kobayashi R, Murayama T, Fukuya S, Tabata K, Fujishiro H, Nakayama M and Naoe J. Evaluating electroconvulsive therapy for dementia with lewy bodies, including the prodromal stage: A retrospective study on safety and efficacy. Int J Geriatr Psychiatry 2024; 39: e70020. DOI: 10.1002/gps.70020.
    25. Mukoyama N, Nishio N, Kimura H, Tokura T, Kishi S, Ogasawara K, Tsuzuki H, Yokoi S, Wada A, Shigeyama M, Ozaki N, Fujimoto Y and Sone M. Anxiety, depression and quality of life in patients with head and neck cancer undergoing laryngectomy: A long-term prospective evaluation. Int J Lang Commun Disord 2024; 59: 1865-1877. 20240422. DOI: 10.1111/1460-6984.13036.
    26. Nakabayashi T, Iwamoto K, Yamaguchi A, Konishi Y, Saji M, Yoshimura R, Kanemoto K, Aoki H, Ando M and Ozaki N. Guideline for evaluating the effects of psychotropic drugs on motor vehicle driving performance in japan: A tiered approach for the assessment of clinically meaningful driving impairment. Neuropsychopharmacol Rep 2024; 44: 308-313. 20240416. DOI: 10.1002/npr2.12436.
    27. Nakamura M, Yoshimi A, Tokura T, Kimura H, Kishi S, Miyauchi T, Iwamoto K, Ito M, Sato-Boku A, Mouri A, Nabeshima T, Ozaki N and Noda Y. Duloxetine improves chronic orofacial pain and comorbid depressive symptoms in association with reduction of serotonin transporter protein through upregulation of ubiquitinated serotonin transporter protein. Pain 2024; 165: 1177-1186. 20240111. DOI: 10.1097/j.pain.0000000000003124.
    28. Nakamura Y, Shimada IS, Maroofian R, Falabella M, Zaki MS, Fujimoto M, Sato E, Takase H, Aoki S, Miyauchi A, Koshimizu E, Miyatake S, Arioka Y, Honda M, Higashi T, Miya F, Okubo Y, Ogawa I, Scardamaglia A, Miryounesi M, Alijanpour S, Ahmadabadi F, Herkenrath P, Dafsari HS, Velmans C, Al Balwi M, Vitobello A, Denommé-Pichon AS, Jeanne M, Civit A, Abdel-Hamid MS, Naderi H, Darvish H, Bakhtiari S, Kruer MC, Carroll CJ, Ghayoor Karimiani E, Khailany RA, Abdulqadir TA, Ozaslan M, Bauer P, Zifarelli G, Seifi T, Zamani M, Al Alam C, Alvi JR, Sultan T, Efthymiou S, Pope SAS, Haginoya K, Matsunaga T, Osaka H, Matsumoto N, Ozaki N, Ohkawa Y, Oki S, Tsunoda T, Pitceathly RDS, Taketomi Y, Houlden H, Murakami M, Kato Y and Saitoh S. Biallelic null variants in pnpla8 cause microcephaly by reducing the number of basal radial glia. Brain 2024; 147: 3949-3967. DOI: 10.1093/brain/awae185.
    29. Nakatochi M, Kushima I, Aleksic B, Kimura H, Kato H, Inada T, Torii Y, Takahashi N, Yamamoto M, Iwamoto K, Nawa Y, Iritani S, Iwata N, Saito T, Ninomiya K, Okochi T, Hashimoto R, Yamamori H, Yasuda Y, Fujimoto M, Miura K, Ohi K, Shioiri T, Kitaichi K, Itokawa M, Arai M, Miyashita M, Toriumi K, Takahashi T, Suzuki M, Kato TA, Kanba S, Horikawa H, Kasai K, Ikegame T, Jinde S, Kato T, Kakiuchi C, Yamagata B, Nio S, Kunii Y, Yabe H, Okamura Y, Tadaka S, Fumihiko U, Obara T, Yamamoto Y, Arioka Y, Mori D, Ikeda M and Ozaki N. Copy number variations in rnf216 and postsynaptic membrane-associated genes are associated with bipolar disorder: A case-control study in the japanese population. Psychiatry Clin Neurosci 2025; 79: 12-20. 20241015. DOI: 10.1111/pcn.13752.
    30. Namba S, Akiyama M, Hamanoue H, Kato K, Kawashima M, Kushima I, Matsuda K, Nakatochi M, Ogishima S, Sonehara K, Suzuki K, Takata A, Tamiya G, Tanikawa C, Yamamoto K, Yamamoto N, Ozaki N and Okada Y. Inconsistent embryo selection across polygenic score methods. Nat Hum Behav 2024; 8: 2264-2267. DOI: 10.1038/s41562-024-02019-y.
    31. Okuda M, Noda A, Iwamoto K, Hishikawa N, Miyata S, Yasuma F, Taoka T, Ozaki N, Suhr JA and Miyazaki S. Assessment of cognitive function and sleep-wake rhythms in community-dwelling older adults. Sleep Biol Rhythms 2024; 22: 137-145. 20230922. DOI: 10.1007/s41105-023-00491-z.
    32. Okumura H, Hayashi Y, Arioka Y, Kushima I, Mori D and Ozaki N. Generation of induced pluripotent stem cells from a schizophrenia patient with heterozygous 1q21.1 deletion. Stem Cell Res 2024; 81: 103555. 20240912. DOI: 10.1016/j.scr.2024.103555.
    33. Otgonbayar G, Lo T, Hayashi Y, Furuta S, Aleksic B, Nawa Y, Kushima I, Kato H, Kimura H and Ozaki N. Study of the genetic association between selected 3q29 region genes and schizophrenia and autism spectrum disorder in the japanese population. Nagoya J Med Sci 2024; 86: 216-222. DOI: 10.18999/nagjms.86.2.216.
    34. Shimamoto M, Ishizuka K, Ohtani K, Inada T, Yamamoto M, Tachibana M, Kimura H, Sakai Y, Kobayashi K, Ozaki N and Ikeda M. Machine learning algorithm-based estimation model for the severity of depression assessed using montgomery-asberg depression rating scale. Neuropsychopharmacol Rep 2024; 44: 115-120. 20231220. DOI: 10.1002/npr2.12404.
    35. Suzuki K, Iwata-Endo K, Suzuki K and Fujishiro H. Late-onset delusional disorder as psychiatric-onset dementia with lewy bodies: A longitudinal follow-up study. Asian J Psychiatr 2024; 102: 104274. 20241012. DOI: 10.1016/j.ajp.2024.104274.
    36. Tachibana M, Inada T, Kimura H, Ito M, Kuwatsuka Y, Kinoshita F, Mori D and Ohno K. Extremely low frequency, extremely low magnetic environment for depression: An open-label trial. Asian J Psychiatr 2024; 96: 104036. 20240326. DOI: 10.1016/j.ajp.2024.104036.
    37. Takahashi N, Ono T, Omori Y, Iizumi M, Kato H, Kasuno S, Persing B and Tsuchiya KJ. Assessment of executive functions using a 3d-video game in children and adolescents with adhd. Front Psychiatry 2024; 15: 1407703. 20240822. DOI: 10.3389/fpsyt.2024.1407703.
    38. Teranishi M, Ito M, Huang Z, Nishiyama Y, Masuda A, Mino H, Tachibana M, Inada T and Ohno K. Extremely low-frequency electromagnetic field (elf-emf) increases mitochondrial electron transport chain activities and ameliorates depressive behaviors in mice. Int J Mol Sci 2024; 25 20241021. DOI: 10.3390/ijms252011315.
    39. Wada S, Iwamoto K, Okumura H, Hida H, Hiraoka S, Kamei A, Mori D, Yamada K, Ando M, Ozaki N and Ikeda M. Effect of single-administration of d-sorbitol pretreatment on the bitterness and continued willingness to take asenapine: A randomized, single-blind, placebo-controlled, crossover trial. BMC Psychiatry 2024; 24: 81. 20240130. DOI: 10.1186/s12888-024-05549-x.
    40. Wakuda T, Benner S, Uemura Y, Nishimura T, Kojima M, Kuroda M, Matsumoto K, Kanai C, Inada N, Harada T, Kameno Y, Munesue T, Inoue J, Umemura K, Yamauchi A, Ogawa N, Kushima I, Suyama S, Saito T, Hamada J, Kano Y, Honda N, Kikuchi S, Seto M, Tomita H, Miyoshi N, Matsumoto M, Kawaguchi Y, Kanai K, Ikeda M, Nakamura I, Isomura S, Hirano Y, Onitsuka T, Ozaki N, Kosaka H, Okada T, Kuwabara H and Yamasue H. Oxytocin-induced increases in cytokines and clinical effect on the core social features of autism: Analyses of rct datasets. Brain Behav Immun 2024; 118: 398-407. 20240308. DOI: 10.1016/j.bbi.2024.03.013.
    41. Zuunnast K, Kato H, Yokoyama K, Nawa Y, Ogawa S, Yoshikawa T, Kaneko H, Nagata M, Davaasuren O, Nomura K. Launching a child and adolescent psychiatry training program in Mongolia inspired by Japanese models. PCN Rep. 2025;4(1):e70056. doi: 10.1002/pcn5.70056.
  • 2023年
    1. Amare A, Thalamuthu A, Schubert KO, Fullerton J, Ahmed M, Hartmann S, Papiol S, Heilbronner U, Degenhardt F, Tekola-Ayele F, Hou L, Hsu YH, Shekhtman T, Adli M, Akula N, Akiyama K, Ardau R, Arias B, Aubry JM, Backlund L, Bhattacharjee AK, Bellivier F, Benabarre A, Bengesser S, Biernacka J, Birner A, Marie-Claire C, Cervantes P, Chen HC, Chillotti C, Cichon S, Cruceanu C, Czerski P, Dalkner N, Del Zompo M, DePaulo JR, Etain B, Jamain S, Falkai P, Forstner AJ, Frisén L, Frye M, Gard S, Garnham J, Goes F, Grigoroiu-Serbanescu M, Fallgatter A, Stegmaier S, Ethofer T, Biere S, Petrova K, Schuster C, Adorjan K, Budde M, Heilbronner M, Kalman J, Oraki Kohshour M, Reich-Erkelenz D, Schaupp S, Schulte E, Senner F, Vogl T, Anghelescu IG, Arolt V, Dannlowski U, Dietrich DE, Figge C, Jäger M, Lang F, Juckel G, Spitzer C, Reimer J, Schmauß M, Schmitt A, Konrad C, von Hagen M, Wiltfang J, Zimmermann J, Andlauer T, Fischer A, Bermpohl F, Kraft V, Matura S, Gryaznova A, Falkenberg I, Yildiz C, Kircher T, Schmidt J, Koch M, Gade K, Trost S, Haußleiter I, Lambert M, Rohenkohl AC, Kraft V, Grof P, Hashimoto R, Hauser J, Herms S, Hoffmann P, Jiménez E, Kahn JP, Kassem L, Kuo PH, Kato T, Kelsoe J, Kittel-Schneider S, Ferensztajn-Rochowiak E, König B, Kusumi I, Laje G, Landén M, Lavebratt C, Leboyer M, Leckband SG, Tortorella A, Manchia M, Martinsson L, McCarthy M, McElroy SL, Colom F, Mitjans M, Mondimore F, Monteleone P, Nievergelt C, Nöthen M, Novak T, O'Donovan C, Ozaki N, Pfennig A, Pisanu C, Potash J, Reif A, Reininghaus E, Rouleau G, Rybakowski JK, Schalling M, Schofield P, Schweizer BW, Severino G, Shilling PD, Shimoda K, Simhandl C, Slaney C, Squassina A, Stamm T, Stopkova P, Maj M, Turecki G, Vieta E, Veeh J, Witt S, Wright A, Zandi P, Mitchell P, Bauer M, Alda M, Rietschel M, McMahon F, Schulze TG, Millischer V, Clark S and Baune B. Association of polygenic score and the involvement of cholinergic and glutamatergic pathways with lithium treatment response in patients with bipolar disorder. Res Sq 2023 20230214. DOI: 10.21203/rs.3.rs-2580252/v1.
    2. Amare AT, Thalamuthu A, Schubert KO, Fullerton JM, Ahmed M, Hartmann S, Papiol S, Heilbronner U, Degenhardt F, Tekola-Ayele F, Hou L, Hsu YH, Shekhtman T, Adli M, Akula N, Akiyama K, Ardau R, Arias B, Aubry JM, Hasler R, Richard-Lepouriel H, Perroud N, Backlund L, Bhattacharjee AK, Bellivier F, Benabarre A, Bengesser S, Biernacka JM, Birner A, Marie-Claire C, Cervantes P, Chen HC, Chillotti C, Cichon S, Cruceanu C, Czerski PM, Dalkner N, Del Zompo M, DePaulo JR, Étain B, Jamain S, Falkai P, Forstner AJ, Frisen L, Frye MA, Gard S, Garnham JS, Goes FS, Grigoroiu-Serbanescu M, Fallgatter AJ, Stegmaier S, Ethofer T, Biere S, Petrova K, Schuster C, Adorjan K, Budde M, Heilbronner M, Kalman JL, Kohshour MO, Reich-Erkelenz D, Schaupp SK, Schulte EC, Senner F, Vogl T, Anghelescu IG, Arolt V, Dannlowski U, Dietrich D, Figge C, Jäger M, Lang FU, Juckel G, Konrad C, Reimer J, Schmauß M, Schmitt A, Spitzer C, von Hagen M, Wiltfang J, Zimmermann J, Andlauer TFM, Fischer A, Bermpohl F, Ritter P, Matura S, Gryaznova A, Falkenberg I, Yildiz C, Kircher T, Schmidt J, Koch M, Gade K, Trost S, Haussleiter IS, Lambert M, Rohenkohl AC, Kraft V, Grof P, Hashimoto R, Hauser J, Herms S, Hoffmann P, Jiménez E, Kahn JP, Kassem L, Kuo PH, Kato T, Kelsoe J, Kittel-Schneider S, Ferensztajn-Rochowiak E, König B, Kusumi I, Laje G, Landén M, Lavebratt C, Leboyer M, Leckband SG, Tortorella A, Manchia M, Martinsson L, McCarthy MJ, McElroy S, Colom F, Millischer V, Mitjans M, Mondimore FM, Monteleone P, Nievergelt CM, Nöthen MM, Novák T, O'Donovan C, Ozaki N, Pfennig A, Pisanu C, Potash JB, Reif A, Reininghaus E, Rouleau GA, Rybakowski JK, Schalling M, Schofield PR, Schweizer BW, Severino G, Shilling PD, Shimoda K, Simhandl C, Slaney CM, Squassina A, Stamm T, Stopkova P, Maj M, Turecki G, Vieta E, Veeh J, Witt SH, Wright A, Zandi PP, Mitchell PB, Bauer M, Alda M, Rietschel M, McMahon FJ, Schulze TG, Clark SR and Baune BT. Association of polygenic score and the involvement of cholinergic and glutamatergic pathways with lithium treatment response in patients with bipolar disorder. Mol Psychiatry 2023; 28: 5251-5261. 20230711. DOI: 10.1038/s41380-023-02149-1.
    3. Aoi T, Tanaka A, Furuhashi K, Ikeya M, Shimizu A, Arioka Y, Kushima I, Ozaki N and Maruyama S. ＜editors' choice＞ mesenchymal stem/stromal cells generated from induced pluripotent stem cells are highly resistant to senescence. Nagoya J Med Sci 2023; 85: 682-690. DOI: 10.18999/nagjms.85.4.682.
    4. Arafuka S, Fujishiro H, Torii Y, Sekiguchi H, Habuchi C, Miwa A, Yoshida M, Iritani S, Iwasaki Y, Ikeda M and Ozaki N. Neuropathological substrate of incident dementia in older patients with schizophrenia: A clinicopathological study. Psychiatry Clin Neurosci 2024; 78: 29-40. 20230929. DOI: 10.1111/pcn.13597.
    5. Arafuka S, Sekiguchi H, Fujishiro H, Iritani S, Torii Y, Habuchi C, Yoshida M, Iwasaki Y, Ozaki N and Fujita K. Late-onset panic disorder as the initial presentation in autopsy-confirmed dementia with lewy bodies. Psychiatry Clin Neurosci 2023; 77: 242-244. 20230206. DOI: 10.1111/pcn.13532.
    6. Arioka Y, Okumura H, Sakaguchi H and Ozaki N. Shedding light on latent pathogenesis and pathophysiology of mental disorders: The potential of ips cell technology. Psychiatry Clin Neurosci 2023; 77: 308-314. 20230404. DOI: 10.1111/pcn.13545.
    7. Fujishiro H, Arafuka S, Ogasawara K, Iwamoto K, Miyata S, Torii Y, Iritani S and Ozaki N. Temporal trajectories of proposed biomarkers in psychiatric-onset prodromal dementia with lewy bodies: A case report. Psychogeriatrics 2023; 23: 196-200. 20221201. DOI: 10.1111/psyg.12922.
    8. Furukawa S, Kushima I, Aleksic B and Ozaki N. Case reports of two siblings with autism spectrum disorder and 15q13.3 deletions. Neuropsychopharmacol Rep 2023; 43: 462-466. 20230601. DOI: 10.1002/npr2.12340.
    9. Hagikura M and Inada T. A case of schizophrenia with relapsed catatonia successfully treated with blonanserin transdermal patch. Neuropsychopharmacol Rep 2023; 43: 150-153. 20230118. DOI: 10.1002/npr2.12314.
    10. Herrera-Rivero M, Adli M, Akiyama K, Akula N, Amare AT, Ardau R, Arias B, Aubry JM, Backlund L, Bellivier F, Benabarre A, Bengesser S, Bhattacharjee AK, Biernacka JM, Birner A, Cearns M, Cervantes P, Chen HC, Chillotti C, Cichon S, Clark SR, Colom F, Cruceanu C, Czerski PM, Dalkner N, Degenhardt F, Del Zompo M, DePaulo JR, Etain B, Falkai P, Ferensztajn-Rochowiak E, Forstner AJ, Frank J, Frisén L, Frye MA, Fullerton JM, Gallo C, Gard S, Garnham JS, Goes FS, Grigoroiu-Serbanescu M, Grof P, Hashimoto R, Hasler R, Hauser J, Heilbronner U, Herms S, Hoffmann P, Hou L, Hsu YH, Jamain S, Jiménez E, Kahn JP, Kassem L, Kato T, Kelsoe J, Kittel-Schneider S, Kuo PH, Kusumi I, König B, Laje G, Landén M, Lavebratt C, Leboyer M, Leckband SG, Maj M, Manchia M, Marie-Claire C, Martinsson L, McCarthy MJ, McElroy SL, Millischer V, Mitjans M, Mondimore FM, Monteleone P, Nievergelt CM, Novák T, Nöthen MM, O'Donovan C, Ozaki N, Papiol S, Pfennig A, Pisanu C, Potash JB, Reif A, Reininghaus E, Richard-Lepouriel H, Roberts G, Rouleau GA, Rybakowski JK, Schalling M, Schofield PR, Schubert KO, Schulte EC, Schweizer BW, Severino G, Shekhtman T, Shilling PD, Shimoda K, Simhandl C, Slaney CM, Squassina A, Stamm T, Stopkova P, Streit F, Tekola-Ayele F, Thalamuthu A, Tortorella A, Turecki G, Veeh J, Vieta E, Viswanath B, Witt SH, Zandi PP, Alda M, Bauer M, McMahon FJ, Mitchell PB, Rietschel M, Schulze TG and Baune BT. Exploring the genetics of lithium response in bipolar disorders. Res Sq 2023 20231202. DOI: 10.21203/rs.3.rs-3677630/v1.
    11. Herrera-Rivero M, Gutiérrez-Fragoso K, Thalamuthu A, Amare AT, Adli M, Akiyama K, Akula N, Ardau R, Arias B, Aubry JM, Backlund L, Bellivier F, Benabarre A, Bengesser S, Abesh B, Biernacka J, Birner A, Cearns M, Cervantes P, Chen HC, Chillotti C, Cichon S, Clark S, Colom F, Cruceanu C, Czerski P, Dalkner N, Degenhardt F, Del Zompo M, DePaulo JR, Etain B, Falkai P, Ferensztajn-Rochowiak E, Forstner AJ, Frank J, Frisen L, Frye M, Fullerton J, Gallo C, Gard S, Garnham J, Goes F, Grigoroiu-Serbanescu M, Grof P, Hashimoto R, Hasler R, Hauser J, Heilbronner U, Herms S, Hoffmann P, Hou L, Hsu Y, Jamain S, Jiménez E, Kahn JP, Kassem L, Kato T, Kelsoe J, Kittel-Schneider S, Kuo PH, Kurtz J, Kusumi I, König B, Laje G, Landén M, Lavebratt C, Leboyer M, Leckband S, Maj M, Manchia M, Marie-Claire C, Martinsson L, McCarthy M, McElroy SL, Millischer V, Mitjans M, Mondimore F, Monteleone P, Nievergelt C, Novak T, Nöthen M, Odonovan C, Ozaki N, Papiol S, Pfennig A, Pisanu C, Potash J, Reif A, Reininghaus E, Richard-Lepouriel H, Roberts G, Rouleau G, Rybakowski JK, Schalling M, Schofield P, Schubert KO, Schulte E, Schweizer B, Severino G, Shekhtman T, Shilling P, Shimoda K, Simhandl C, Slaney C, Squassina A, Stamm T, Stopkova P, Streit F, Ayele F, Tortorella A, Turecki G, Veeh J, Vieta E, Viswanath B, Witt S, Zandi P, Alda M, Bauer M, McMahon F, Mitchell P, Rietschel M, Schulze T and Baune B. Immunogenetics of lithium response and psychiatric phenotypes in patients with bipolar disorder. Res Sq 2023 20230626. DOI: 10.21203/rs.3.rs-3068352/v1.
    12. Ito T, Yoshida M, Aida T, Kushima I, Hiramatsu Y, Ono M, Yoshimi A, Tanaka K, Ozaki N and Noda Y. Astrotactin 2 (astn2) regulates emotional and cognitive functions by affecting neuronal morphogenesis and monoaminergic systems. J Neurochem 2023; 165: 211-229. 20230315. DOI: 10.1111/jnc.15790.
    13. Iwamoto K, Nakabayashi T, Yamaguchi A, Konishi Y, Saji M, Yoshimura R, Kanemoto K, Aoki H, Ando M and Ozaki N. The new guideline for evaluating effects of psychotropic drugs on the performance to drive a motor vehicle in japan: Comparison with us fda guideline. Neuropsychopharmacol Rep 2023; 43: 172-176. 20230414. DOI: 10.1002/npr2.12339.
    14. Kato H, Kimura H, Kushima I, Takahashi N, Aleksic B and Ozaki N. The genetic architecture of schizophrenia: Review of large-scale genetic studies. J Hum Genet 2023; 68: 175-182. 20220712. DOI: 10.1038/s10038-022-01059-4.
    15. Kato S, Maesawa S, Bagarinao E, Nakatsubo D, Tsugawa T, Mizuno S, Kawabata K, Tsuboi T, Suzuki M, Shibata M, Takai S, Ishizaki T, Torii J, Mutoh M, Saito R, Wakabayashi T, Katsuno M, Ozaki N, Watanabe H and Sobue G. Magnetic resonance-guided focused ultrasound thalamotomy restored distinctive resting-state networks in patients with essential tremor. J Neurosurg 2023; 138: 306-317. 20220708. DOI: 10.3171/2022.5.Jns22411.
    16. Kawai K, Iwamoto K, Miyata S, Okada I, Ando M, Fujishiro H, Ando M, Noda A and Ozaki N. Lps and its relationship with subjective-objective discrepancies of sleep onset latency in patients with psychiatric disorders. Sci Rep 2023; 13: 22637. 20231219. DOI: 10.1038/s41598-023-49261-4.
    17. Kawai K, Iwamoto K, Miyata S, Okada I, Fujishiro H, Noda A, Nakagome K, Ozaki N and Ikeda M. Comparison of polysomnography, single-channel electroencephalogram, fitbit, and sleep logs in patients with psychiatric disorders: Cross-sectional study. J Med Internet Res 2023; 25: e51336. 20231213. DOI: 10.2196/51336.
    18. Kelsoe J, Ou A, Rosenthal S, Adli M, Akiyama K, Akula N, Alda M, Amare AT, Ardau R, Arias B, Aubry JM, Backlund L, Banzato C, Bauer M, Baune B, Bellivier F, Benabarre A, Bengesser S, Abesh B, Biernacka J, Bui E, Cervantes P, Chen GB, Chen HC, Chillotti C, Cichon S, Clark S, Colom F, Cousins D, Cruceanu C, Czerski P, Dantas C, Dayer A, Degenhardt F, DePaulo JR, Etain B, Falkai P, Fellendorf F, Ferensztajn-Rochowiak E, Forstner AJ, Frisen L, Frye M, Fullerton J, Gard S, Garnham J, Goes F, Grigoroiu-Serbanescu M, Grof P, Gruber O, Hashimoto R, Hauser J, Heilbronner U, Herms S, Hoffmann P, Hofmann A, Hou L, Jamain S, Jiménez E, Kahn JP, Kassem L, Kato T, Kittel-Schneider S, König B, Kuo PH, Kusumi I, Dalkner N, Laje G, Landén M, Lavebratt C, Leboyer M, Leckband S, Jaramillo CL, MacQueen G, Maj M, Manchia M, Marie-Claire C, Martinsson L, Mattheisen M, McCarthy M, McElroy S, McMahon F, Mitchell P, Mitjans M, Mondimore F, Monteleone P, Nievergelt C, Nöthen M, Novak T, Osby U, Ozaki N, Papiol S, Perlis R, Pfennig A, Potash J, Reich-Erkelenz D, Reif A, Reininghaus E, Rietschel M, Rouleau G, Rybakowski JK, Schalling M, Schofield P, Schubert KO, Schulze T, Schweizer B, Seemüller F, Severino G, Shekhtman T, Shilling P, Shimoda K, Simhandl C, Slaney C, Squassina A, Stamm T, Stopkova P, Tighe S, Tortorella A, Turecki G, Vieta E, Volkert J, Witt S, Wray N, Wright A, Young T, Zandi P and Zompo MD. Lithium response in bipolar disorder is associated with focal adhesion and pi3k-akt networks: A multi-omics replication study. Res Sq 2023 20231003. DOI: 10.21203/rs.3.rs-3258813/v1.
    19. Kimura H, Kishi S, Narita H, Tanaka T, Okada T, Fujisawa D, Sugita N, Noma S, Matsumoto Y, Ohashi A, Mitsuyasu H, Yoshida K, Kawasaki H, Nishimura K, Ogura Y and Ozaki N. Comorbid psychiatric disorders and long-term survival after liver transplantation in transplant facilities with a psychiatric consultation-liaison team: A multicenter retrospective study. BMC Gastroenterol 2023; 23: 106. 20230405. DOI: 10.1186/s12876-023-02735-1.
    20. Kimura H, Kushima I, Banno M, Inada T, Yoshimi A, Aleksic B and Ozaki N. Clinical characterization of patients with schizophrenia and 16p13.11 duplication: A case series. Neuropsychopharmacol Rep 2023; 43: 267-271. 20230428. DOI: 10.1002/npr2.12334.
    21. Kubota C, Inada T, Lin SK, Avasthi A, Chee KY, Tanra AJ, Yang SY, Chen LY, Chong MY, Tripathi A, Kallivayalil RA, Grover S, Park SC, Kato TA, Xiang YT, Sim K, Maramis MM, Noor IM, Tan CH, Sartorius N and Shinfuku N. The factor structure of extrapyramidal symptoms evaluated using the drug-induced extrapyramidal symptoms scale in patients with schizophrenia: Results from the 2016 reap ap-4 study. Hum Psychopharmacol 2023; 38: e2861. 20221203. DOI: 10.1002/hup.2861.
    22. Liao J, Dong G, Zhu W, Wulaer B, Mizoguchi H, Sawahata M, Liu Y, Kaibuchi K, Ozaki N, Nabeshima T, Nagai T and Yamada K. Rho kinase inhibitors ameliorate cognitive impairment in a male mouse model of methamphetamine-induced schizophrenia. Pharmacol Res 2023; 194: 106838. 20230628. DOI: 10.1016/j.phrs.2023.106838.
    23. Lo T, Kushima I, Aleksic B, Yoshimi A, Someya T, Watanabe Y and Ozaki N. Clinical manifestations of schizophrenia in four patients with variants in voltage-gated calcium channel-encoding genes: A case series. Psychiatry Clin Neurosci 2023; 77: 57-59. 20221109. DOI: 10.1111/pcn.13494.
    24. Lo T, Kushima I, Kimura H, Aleksic B, Okada T, Kato H, Inada T, Nawa Y, Torii Y, Yamamoto M, Kimura R, Funabiki Y, Kosaka H, Numata S, Kasai K, Sasaki T, Yokoyama S, Munesue T, Hashimoto R, Yasuda Y, Fujimoto M, Usami M, Itokawa M, Arai M, Ohi K, Someya T, Watanabe Y, Egawa J, Takahashi T, Suzuki M, Yamasue H, Iwata N, Ikeda M and Ozaki N. Association between copy number variations in parkin (prkn) and schizophrenia and autism spectrum disorder: A case-control study. Neuropsychopharmacol Rep 2024; 44: 42-50. 20231101. DOI: 10.1002/npr2.12370.
    25. Matsumoto J, Fukunaga M, Miura K, Nemoto K, Okada N, Hashimoto N, Morita K, Koshiyama D, Ohi K, Takahashi T, Koeda M, Yamamori H, Fujimoto M, Yasuda Y, Ito S, Yamazaki R, Hasegawa N, Narita H, Yokoyama S, Mishima R, Miyata J, Kobayashi Y, Sasabayashi D, Harada K, Yamamoto M, Hirano Y, Itahashi T, Nakataki M, Hashimoto RI, Tha KK, Koike S, Matsubara T, Okada G, Yoshimura R, Abe O, van Erp TGM, Turner JA, Jahanshad N, Thompson PM, Onitsuka T, Watanabe Y, Matsuo K, Yamasue H, Okamoto Y, Suzuki M, Ozaki N, Kasai K and Hashimoto R. Cerebral cortical structural alteration patterns across four major psychiatric disorders in 5549 individuals. Mol Psychiatry 2023; 28: 4915-4923. 20230818. DOI: 10.1038/s41380-023-02224-7.
    26. Miyake N, Tsurusaki Y, Fukai R, Kushima I, Okamoto N, Ohashi K, Nakamura K, Hashimoto R, Hiraki Y, Son S, Kato M, Sakai Y, Osaka H, Deguchi K, Matsuishi T, Takeshita S, Fattal-Valevski A, Ekhilevitch N, Tohyama J, Yap P, Keng WT, Kobayashi H, Takubo K, Okada T, Saitoh S, Yasuda Y, Murai T, Nakamura K, Ohga S, Matsumoto A, Inoue K, Saikusa T, Hershkovitz T, Kobayashi Y, Morikawa M, Ito A, Hara T, Uno Y, Seiwa C, Ishizuka K, Shirahata E, Fujita A, Koshimizu E, Miyatake S, Takata A, Mizuguchi T, Ozaki N and Matsumoto N. Molecular diagnosis of 405 individuals with autism spectrum disorder. Eur J Hum Genet 2024; 32: 1551-1558. 20230327. DOI: 10.1038/s41431-023-01335-7.
    27. Miyata S, Iwamoto K and Ozaki N. Evaluating sleep-wake rhythm using a wearable device in patients with mental disorders. Psychiatry Clin Neurosci 2023; 77: 419. 20230628. DOI: 10.1111/pcn.13568.
    28. Mizutani R, Saiga R, Yamamoto Y, Uesugi M, Takeuchi A, Uesugi K, Terada Y, Suzuki Y, De Andrade V, De Carlo F, Takekoshi S, Inomoto C, Nakamura N, Torii Y, Kushima I, Iritani S, Ozaki N, Oshima K, Itokawa M and Arai M. Structural aging of human neurons is opposite of the changes in schizophrenia. PLoS One 2023; 18: e0287646. 20230623. DOI: 10.1371/journal.pone.0287646.
    29. Nakagome K, Makinodan M, Uratani M, Kato M, Ozaki N, Miyata S, Iwamoto K, Hashimoto N, Toyomaki A, Mishima K, Ogasawara M, Takeshima M, Minato K, Fukami T, Oba M, Takeda K and Oi H. Feasibility of a wrist-worn wearable device for estimating mental health status in patients with mental illness. Front Psychiatry 2023; 14: 1189765. 20230720. DOI: 10.3389/fpsyt.2023.1189765.
    30. Ogasawara M, Takeshima M, Kosaka S, Imanishi A, Itoh Y, Fujiwara D, Yoshizawa K, Ozaki N, Nakagome K and Mishima K. Exploratory validation of sleep-tracking devices in patients with psychiatric disorders. Nat Sci Sleep 2023; 15: 301-312. 20230424. DOI: 10.2147/nss.S400944.
    31. Ohgidani M, Kushima I, Inamine S, Kyuragi S, Sagata N, Nakao T, Kanba S, Ozaki N and Kato TA. A case of bipolar disorder with aif1 (coding gene of iba-1) deletion: A pilot in vitro analysis using blood-derived microglia-like cells. Psychiatry Clin Neurosci 2023; 77: 128-130. 20221124. DOI: 10.1111/pcn.13505.
    32. Okada N, Fukunaga M, Miura K, Nemoto K, Matsumoto J, Hashimoto N, Kiyota M, Morita K, Koshiyama D, Ohi K, Takahashi T, Koeda M, Yamamori H, Fujimoto M, Yasuda Y, Hasegawa N, Narita H, Yokoyama S, Mishima R, Kawashima T, Kobayashi Y, Sasabayashi D, Harada K, Yamamoto M, Hirano Y, Itahashi T, Nakataki M, Hashimoto RI, Tha KK, Koike S, Matsubara T, Okada G, van Erp TGM, Jahanshad N, Yoshimura R, Abe O, Onitsuka T, Watanabe Y, Matsuo K, Yamasue H, Okamoto Y, Suzuki M, Turner JA, Thompson PM, Ozaki N, Kasai K and Hashimoto R. Subcortical volumetric alterations in four major psychiatric disorders: A mega-analysis study of 5604 subjects and a volumetric data-driven approach for classification. Mol Psychiatry 2023; 28: 5206-5216. 20230804. DOI: 10.1038/s41380-023-02141-9.
    33. Okuda M, Noda A, Iwamoto K, Hishikawa N, Miyata S, Yasuma F, Taoka T, Ozaki N, Suhr JA and Miyazaki S. Assessment of cognitive function and sleep-wake rhythms in community-dwelling older adults. Sleep Biol Rhythms 2024; 22: 137-145. 20230922. DOI: 10.1007/s41105-023-00491-z.
    34. Ozaki N, Kimura T, Kikuchi T and Ishiyama T. Neuropsychopharmacology renaissance in Japan: A new era after the crisis. Psychiatry Clin Neurosci 2023; 77: 375-376. 20230413. DOI: 10.1111/pcn.13549.
    35. Saito T, Ikeda M, Terao C, Ashizawa T, Miyata M, Tanaka S, Kanazawa T, Kato T, Kishi T and Iwata N. Differential genetic correlations across major psychiatric disorders between eastern and western countries. Psychiatry Clin Neurosci 2023; 77: 118-119. 20221117. DOI: 10.1111/pcn.13498.
    36. Sato-Boku A, Tokura T, Kimura H, Ito M, Kishi S, Tonoike T, Ozaki N, Nakano Y, Hosijima H and Tachi N. The usefulness of the short form-8 for chronic pain in the orofacial region: A prospective cohort study. Cureus 2023; 15: e45586. 20230920. DOI: 10.7759/cureus.45586.
    37. Senica N, Aleksic B, Inada T, Iljes AP, Zamuda T and Kumperscak HG. Slovenian version of the drug-induced extrapyramidal symptoms scale: Evaluation of interrater and test-retest reliability. J Clin Psychopharmacol 2023; 43: 361-364. 20230501. DOI: 10.1097/jcp.0000000000001682.
    38. Shimamoto M, Ishizuka K, Ohtani K, Inada T, Yamamoto M, Tachibana M, Kimura H, Sakai Y, Kobayashi K, Ozaki N and Ikeda M. Machine learning algorithm-based estimation model for the severity of depression assessed using montgomery-asberg depression rating scale. Neuropsychopharmacol Rep 2024; 44: 115-120. 20231220. DOI: 10.1002/npr2.12404.
    39. Suzuki K, Nishio N, Kimura H, Tokura T, Kishi S, Ozaki N, Fujimoto Y and Sone M. Comparison of quality of life and psychological distress in patients with tongue cancer undergoing a total/subtotal glossectomy or extended hemiglossectomy and free flap transfer: A prospective evaluation. Int J Oral Maxillofac Surg 2023; 52: 621-629. 20221202. DOI: 10.1016/j.ijom.2022.11.010.
    40. Tabata H, Mori D, Matsuki T, Yoshizaki K, Asai M, Nakayama A, Ozaki N and Nagata KI. Histological analysis of a mouse model of the 22q11.2 microdeletion syndrome. Biomolecules 2023; 13 20230427. DOI: 10.3390/biom13050763.
    41. Tachibana M and Inada T. Poor prognostic impact of delirium: Especially on mortality and institutionalisation. Psychogeriatrics 2023; 23: 187-195. 20221123. DOI: 10.1111/psyg.12914.
    42. Takahashi N, Nishimura T, Harada T, Okumura A, Iwabuchi T, Rahman MS, Kuwabara H, Takagai S, Usui N, Makinodan M, Matsuzaki H, Ozaki N, Itoh H, Nomura Y, Newcorn JH and Tsuchiya KJ. Interaction of genetic liability for attention deficit hyperactivity disorder (adhd) and perinatal inflammation contributes to adhd symptoms in children. Brain Behav Immun Health 2023; 30: 100630. 20230518. DOI: 10.1016/j.bbih.2023.100630.
    43. Tanaka R, Liao J, Hada K, Mori D, Nagai T, Matsuzaki T, Nabeshima T, Kaibuchi K, Ozaki N, Mizoguchi H and Yamada K. Inhibition of rho-kinase ameliorates decreased spine density in the medial prefrontal cortex and methamphetamine-induced cognitive dysfunction in mice carrying schizophrenia-associated mutations of the arhgap10 gene. Pharmacol Res 2023; 187: 106589. 20221130. DOI: 10.1016/j.phrs.2022.106589.
    44. Terashima A, Ogasawara K and Ozaki N. [psychotropic medication in pregnant and postpartum women]. Brain Nerve 2023; 75: 1043-1049. DOI: 10.11477/mf.1416202468.
    45. Torii Y, Iritani S, Fujishiro H, Sekiguchi H, Habuchi C, Ikeda T, Yoshida M, Iwasaki Y, Ozaki N and Kawashima K. An autopsy case of schizophrenia comorbid with argyrophilic grain disease. Psychogeriatrics 2023; 23: 371-373. 20230119. DOI: 10.1111/psyg.12935.
    46. Wada S, Iwamoto K, Okumura H, Hida H, Hiraoka S, Kamei A, Mori D, Yamada K and Ozaki N. Sensory evaluation of the bitterness of asenapine using d-sorbitol pretreatment: Single-blind, placebo-controlled, crossover trial. BMC Psychiatry 2023; 23: 159. 20230314. DOI: 10.1186/s12888-023-04664-5.
    47. Wada S, Ogasawara K and Ozaki N. [how to use psychotropic drugs during the perinatal period: Risks and benefits for fetuses and infants]. Brain Nerve 2023; 75: 645-651. DOI: 10.11477/mf.1416202392.
    48. Yamamoto H, Lee-Okada HC, Ikeda M, Nakamura T, Saito T, Takata A, Yokomizo T, Iwata N, Kato T and Kasahara T. Gwas-identified bipolar disorder risk allele in the fads1/2 gene region links mood episodes and unsaturated fatty acid metabolism in mutant mice. Mol Psychiatry 2023; 28: 2848-2856. 20230221. DOI: 10.1038/s41380-023-01988-2.
    49. Yamamoto M and Inada T. Positron emission tomography studies in adult patients with attention-deficit/hyperactivity disorder. Jpn J Radiol 2023; 41: 382-392. 20221208. DOI: 10.1007/s11604-022-01368-w.
  • 2022年
    1. Arafuka S, Fujishiro H, Iritani S, Torii Y, Miwa A, Yabata H, Sekiguchi H, Habuchi C, Kawashima K, Yoshida M, Iwasaki Y, Ozaki N. Striatal i-123-2 beta-carbomethoxy-3b-(4-iodophenyl)-n-(3-fluoropropyl)-nortropane single-photon emission computed tomography demonstrates nigral degeneration in the early stage of behavioural variant frontotemporal dementia: An autopsy case with frontotemporal lobar degeneration with trans-activation response DNA protein 43 type b. Psychogeriatrics. 2022;22(4):580-585.
    2. Arafuka S, Sekiguchi H, Fujishiro H, Iritani S, Torii Y, Habuchi C, Yoshida M, Iwasaki Y, Ozaki N, Fujita K. Late-onset panic disorder as the initial presentation in autopsy-confirmed dementia with lewy bodies. Psychiatry and Clinical Neurosciences. 2023;77(4):242-244.
    3. Fujishiro H, Arafuka S, Ogasawara K, Iwamoto K, Miyata S, Torii Y, Iritani S, Ozaki N. Temporal trajectories of proposed biomarkers in psychiatric-onset prodromal dementia with lewy bodies: A case report. Psychogeriatrics. 2023;23(1):196-200.
    4. Furuta S, Aleksic B, Nawa Y, Kimura H, Kushima I, Ishizuka K, Kato H, Toyama M, Arioka Y, Mori D, Morikawa M, Inada T, Ozaki N. Investigation of olig2 as a candidate gene for schizophrenia and autism spectrum disorder. Nagoya Journal of Medical Science. 2022;84(2):260-268.
    5. Hagikura M, Inada T. A case of schizophrenia with relapsed catatonia successfully treated with blonanserin transdermal patch. Neuropsychopharmacology Reports. 2023;43(1):150-153.
    6. Ishizuka K, Tachibana M, Inada T. Possible Commonalities of Clinical Manifestations Between Dystonia and Catatonia. Front Psychiatry. 2022;13:876678.
    7. Ito T, Yoshida M, Aida T, Kushima I, Hiramatsu Y, Ono M, Yoshimi A, Tanaka K, Ozaki N, Noda Y. Astrotactin 2 (astn2) regulates emotional and cognitive functions by affecting neuronal morphogenesis and monoaminergic systems. Journal of Neurochemistry. 2023;165(2):211-229.
    8. Kaminogo K, Yamaguchi S, Tokura T, Kimura H, Kishi S, Yamamoto N, Ozaki N, Hibi H. Coping styles and quality of life in oral cancer patients undergoing radical resection and free flap reconstruction. Oral Oncology Reports. 2023;5:100015.
    9. Kato S, Bagarinao E, Isoda H, Koyama S, Watanabe H, Maesawa S, Hara K, Katsuno M, Naganawa S, Ozaki N, Sobue G. Reproducibility of functional connectivity metrics estimated from resting-state functional mri with differences in days, coils, and global signal regression. Radiological Physics and Technology. 2022;15(4):298-310.
    10. Kawabata K, Bagarinaob E, Watanabe H, Maesawab S, Mori D, Hara K, Ohdake R, Masuda M, Ogura A, Kato T, Koyama S, Katsuno M, Wakabayashi T, Kuzuya M, Hoshiyama M, Isoda H, Naganawa S, Ozaki N, Sobue G. Functional connector hubs in the cerebellum. Neuroimage. 2022;257:119263.
    11. Kawai K, Iwamoto K, Miyata S, Okada I, Ando M, Fujishiro H, Noda A, Ozaki N. A Study of Factors Causing Sleep State Misperception in Patients with Depression. Nat Sci Sleep. 2022;14:1273-1283.
    12. Kawakami I, Iga JI, Takahashi S, Lin Y-T, Fujishiro H. Towards an understanding of the pathological basis of senile depression and incident dementia: implications for treatment. Psychiatry Clin Neurosci 2022;76(12):620-632.
    13. Kimura H, Nakatochi M, Aleksic B, Guevara J, Toyama M, Hayashi Y, Kato H, Kushima I, Morikawa M, Ishizuka K, Okada T, Tsurusaki Y, Fujita A, Miyake N, Ogi T, Takata A, Matsumoto N, Buxbaum J, Ozaki N, Sebat J. Exome sequencing analysis of japanese autism spectrum disorder case-control sample supports an increased burden of synaptic function-related genes. Translational Psychiatry. 2022;12(1):265.
    14. Kimura H, Yokoyama H, Torii Y, Fujishiro H. Electroconvulsive therapy as a potential therapeutic option in psychiatric-onset prodromal dementia with Lewy bodies. Int J Geriatr Psychiatry 2023; 38(1):e5863.
    15. Kubota C, Inada T, Lin SK, Avasthi A, Chee KY, Tanra AJ, Yang SY, Chen LY, Chong MY, Tripathi A, Kallivayalil RA, Grover S, Park SC, Kato TA, Xiang YT, Sim K, Maramis MM, Noor IM, Tan CH, Sartorius N, Shinfuku N. The factor structure of extrapyramidal symptoms evaluated using the drug-induced extrapyramidal symptoms scale in patients with schizophrenia: Results from the 2016 reap ap-4 study. Human Psychopharmacology-Clinical and Experimental. 2023;38(2):e2861.
    16. Kushima I, Aleksic B, Kimura H, Nakatochi M, Lo T, Ikeda M, Arai M, Hashimoto R, Numata S, Okamura Y, Obara T, Inada T, Ozaki N. X chromosome aneuploidies and schizophrenia: Association analysis and phenotypic characterization. Psychiatry and Clinical Neurosciences. 2022;76(12):667-673.
    17. Kushima I, Imaeda M, Tanaka S, Kato H, Oya-Ito T, Nakatochi M, Aleksic B, Ozaki N. Contribution of copy number variations to the risk of severe eating disorders. Psychiatry and Clinical Neurosciences. 2022;76(9):423-428.
    18. Kushima I, Nakatochi M, Aleksic B, Okada T, Kimura H, Kato H, Morikawa M, Inada T, Ishizuka K, Torii Y, Nakamura Y, Tanaka S, Imaeda M, Takahashi N, Yamamoto M, Iwamoto K, Nawa Y, Ogawa N, Iritani S, Hayashi Y, Lo TY, Otgonbayar G, Furuta S, Iwata N, Ikeda M, Saito T, Ninomiya K, Okochi T, Hashimoto R, Yamamori H, Yasuda Y, Fujimoto M, Miura K, Itokawa M, Arai M, Miyashita M, Toriumi K, Ohi K, Shioiri T, Kitaichi K, Someya T, Watanabe Y, Egawa J, Takahashi T, Suzuki M, Sasaki T, Tochigi M, Nishimura F, Yamasue H, Kuwabara H, Wakuda T, Kato TA, Kanba S, Horikawa H, Usami M, Kodaira M, Watanabe K, Yoshikawa T, Toyota T, Yokoyama S, Munesue T, Kimura R, Funabiki Y, Kosaka H, Jung MY, Kasai K, Ikegame T, Jinde S, Numata S, Kinoshita M, Kato T, Kakiuchi C, Yamakawa K, Suzuki T, Hashimoto N, Ishikawa S, Yamagata B, Nio S, Murai T, Son S, Kunii Y, Yabe H, Inagaki M, Goto YI, Okumura Y, Ito T, Arioka Y, Mori D, Ozaki N. Cross-disorder analysis of genic and regulatory copy number variations in bipolar disorder, schizophrenia, and autism spectrum disorder. Biological Psychiatry. 2022;92(5):362-374.
    19. Kushima I, Uematsu M, Ishizuka K, Aleksic B, Ozaki N. Psychiatric patients with a de novo 17q12 deletion: Two case reports. Psychiatry and Clinical Neurosciences. 2022;76(7):345-347.
    20. Lo T, Kushima I, Aleksic B, Kato H, Nawa Y, Hayashi Y, Otgonbayar G, Kimura H, Arioka Y, Mori D, Ozaki N. Sequencing of selected chromatin remodelling genes reveals increased burden of rare missense variants in asd patients from the japanese population. International Review of Psychiatry. 2022;34(2):154-167.
    21. Lo TY, Kushima I, Aleksic B, Yoshimi A, Someya T, Watanabe Y, Ozaki N. Clinical manifestations of schizophrenia in four patients with variants in voltage-gated calcium channel-encoding genes: A case series. Psychiatry and Clinical Neurosciences. 2023;77(1):57-59.
    22. Miyake N, Tsurusaki Y, Fukai R, Kushima I, Okamoto N, Ohashi K, Nakamura K, Hashimoto R, Hiraki Y, Son S, Kato M, Sakai Y, Osaka H, Deguchi K, Matsuishi T, Takeshita S, Fattal-Valevski A, Ekhilevitch N, Tohyama J, Yap P, Keng WT, Kobayashi H, Takubo K, Okada T, Saitoh S, Yasuda Y, Murai T, Nakamura K, Ohga S, Matsumoto A, Inoue K, Saikusa T, Hershkovitz T, Kobayashi Y, Morikawa M, Ito A, Hara T, Uno Y, Seiwa C, Ishizuka K, Shirahata E, Fujita A, Koshimizu E, Miyatake S, Takata A, Mizuguchi T, Ozaki N, Matsumoto N. Molecular diagnosis of 405 individuals with autism spectrum disorder. European Journal of Human Genetics. 2023.
    23. Miyata S, Otake H, Fujishiro H, Iwamo K, Noda A, Sone M, Ozaki N. Polysomnographic characteristics and predictors of positional obstructive sleep apnea in Japanese elderly. Sleep Biol. Rhythms. 2022;20:403-411.
    24. Mizobuchi K, Kushima I, Kato H, Miyajima M, Kimura H, Ozaki N. Turner syndrome presenting with idiopathic regression: A case report. Psychiatry and Clinical Neurosciences. 2022;76(12):680-682.
    25. Nawa Y, Kushima I, Aleksic B, Yamamoto M, Kimura H, Banno M, Hashimoto R, Ozaki N. Treatment-resistant schizophrenia in patients with 3q29 deletion: A case series of four patients. Psychiatry and Clinical Neurosciences. 2022;76(7):338-339.
    26. Nishimura T, Takahashi N, Okumura A, Harada T, Iwabuchi T, Nakayasu C, Rahman MS, Uchiyama S, Wakuta M, Nomura Y, Takei N, Senju A, Tsuchiya KJ. Sex differences in neurodevelopmental trajectories in children with different levels of autistic traits. Psychiatry Clin Neurosci. 2023;77(5):282-289.
    27. Nishimura T, Kato T, Okumura A, Harada T, Iwabuchi T, Rahman MS, Hirota T, Takahashi M, Adachi M, Kuwabara H, Takagai S, Nomura Y, Takahashi N, Senju A, Tsuchiya KJ. Trajectories of Adaptive Behaviors During Childhood in Females and Males in the General Population. Front Psychiatry. 2022;13:817383.
    28. Ogasawara M, Takeshima M, Kosaka S, Imanishi A, Itoh Y, Fujiwara D, Yoshizawa K, Ozaki N, Nakagome K, Mishima K. Exploratory validation of sleep-tracking devices in patients with psychiatric disorders. Nature and Science of Sleep. 2023;15:301-312.
    29. Oh HS, Lee BJ, Lee YS, Jang OJ, Nakagami Y, Inada T, Kato TA, Kanba S, Chong MY, Lin SK, Si TM, Xiang YT, Avasthi A, Grover S, Kallivayalil RA, Pariwatcharakul P, Chee KY, Tanra AJ, Rabbani G, Javed A, Kathiarachchi S, Myint WA, Cuong TV, Wang YX, Sim K, Sartorius N, Tan CH, Shinfuku N, Park YC, Park SC. Machine learning algorithm-based prediction model for the augmented use of clozapine with electroconvulsive therapy in patients with schizophrenia. Journal of Personalized Medicine. 2022;12(6):969.
    30. Oh J, Shin HM, Nishimura T, Rahman MS, Takahashi N, Tsuchiya KJ. Perfluorooctanoate and perfluorooctane sulfonate in umbilical cord blood and child cognitive development: Hamamatsu Birth Cohort for Mothers and Children (HBC Study). Environ Int. 2022;163:107215.
    31. Ohgidani M, Kushima I, Inamine S, Kyuragi S, Sagata N, Nakao T, Kanba S, Ozaki N, Kato TA. A case of bipolar disorder with aif1 (coding gene of iba-1) deletion: A pilot in vitro analysis using blood-derived microglia-like cells. Psychiatry and Clinical Neurosciences. 2023;77(2):128-130.
    32. Okada I, Miyata S, Iwamoto K, Fujishiro H, Noda A, Ozaki N. Prevalence of obstructive sleep apnea as assessed by polysomnography in psychiatric patients with sleep-related problems. Sleep Breath. 2022;26(4):1983-1991.
    33. Okumura H, Arioka Y, Kushima I, Mori D, Ozaki N. Establishment of induced pluripotent stem cells from a patient with 16p13.11 duplication and vps13b deletion. Stem Cell Research. 2022;64:102884.
    34. Sugiyama M, Tsuchiya KJ, Okubo Y, Rahman MS, Uchiyama S, Harada T, Iwabuchi T, Okumura A, Nakayasu C, Amma Y, Suzuki H, Takahashi N, Kinsella-Kammerer B, Nomura Y, Itoh H, Nishimura T. Outdoor Play as a Mitigating Factor in the Association Between Screen Time for Young Children and Neurodevelopmental Outcomes. JAMA Pediatr. 2023;177(3):303-310.
    35. sSumiyoshi C, Ohi K, Fujino H, Yamamori H, Fujimoto M, Yasuda Y, Uno Y, Takahashi J, Morita K, Katsuki A, Yamamoto M, Okahisa Y, Sata A, Katsumoto E, Koeda M, Hirano Y, Nakataki M, Matsumoto J, Miura K, Hashimoto N, Makinodan M, Takahashi T, Nemoto K, Kishimoto T, Suzuki M, Sumiyoshi T, Hashimoto R. Transdiagnostic comparisons of intellectual abilities and work outcome in patients with mental disorders: multicentre study. BJPsych Open. 2022;8(4):e98.
    36. Tachibana M, Inada T, Ichida M, Ozaki N. Prevalence, clinical features, and risk factors of delusions in patients with delirium. International Journal of Geriatric Psychiatry. 2022;37(6).
    37. Tachibana M, Inada T. Poor prognostic impact of delirium: especially on mortality and institutionalisation. Psychogeriatrics. 2023;23(1):187-195.
    38. Tachibana M, Ishizuka K, Inada T. Catatonia and Delirium: Similarity and Overlap of Acute Brain Dysfunction. Front Psychiatry. 2022;13:876727.
    39. Tainaka H, Takahashi N, Nishimura T, Okumura A, Harada T, Iwabuchi T, Rahman MS, Nomura Y, Tsuchiya KJ. Long-term effect of persistent postpartum depression on children's psychological problems in childhood. J Affect Disord. 2022;305:71-76.
    40. Takase S, Liao JZ, Liu Y, Tanaka R, Miyagawa Y, Sawahata M, Sobue A, Mizoguchi H, Nagai T, Kaibuchi K, Ozaki N, Yamada K. Antipsychotic-like effects of fasudil, a rho-kinase inhibitor, in a pharmacologic animal model of schizophrenia. European Journal of Pharmacology. 2022;931.
    41. Tanaka R, Liao JZ, Hada K, Mori D, Nagai T, Matsuzaki T, Nabeshima T, Kaibuchi K, Ozaki N, Mizoguchi H, Yamada K. Inhibition of rho-kinase ameliorates decreased spine density in the medial prefrontal cortex and methamphetamine-induced cognitive dysfunction in mice carrying schizophrenia-associated mutations of the arhgap10 gene. Pharmacological Research. 2023;187:106589.
    42. Torii Y, Iritani S, Fujishiro H, Sekiguchi H, Habuchi C, Ikeda T, Yoshida M, Iwasaki Y, Ozaki N, Kawashima K. An autopsy case of schizophrenia comorbid with pure argyrophilic grain disease. Psychogeriatrics 2023;23(2)371-373.
    43. Torii-Goto A, Yoshimi A, Tashiro Y, Ukigai M, Matsumoto A, Ozaki N, Noda Y. A reactive metabolite of clozapine induces hematopoietic toxicity in hl-60 cells undergoing granulocytic differentiation through its effect on glutathione metabolism. Biological & Pharmaceutical Bulletin. 2022;45(9):1232-1237.
    44. Tsujikawa K, Hamanaka K, Riku Y, Hattori Y, Hara N, Iguchi Y, Ishigaki S, Hashizume A, Miyatake S, Mitsuhashi S, Miyazaki Y, Kataoka M, Li JY, Yasui K, Kuru S, Koike H, Kobayashi K, Sahara N, Ozaki N, Yoshida M, Kakita A, Saito Y, Iwasaki Y, Miyashita A, Iwatsubo T, Ikeuchi T, Miyata T, Sobue G, Matsumoto N, Sahashi K, Katsuno M, Japanese Alzheimer's Dis N, Japanese Longitudinal Biomarker S. Actin-binding protein filamin-a drives tau aggregation and contributes to progressive supranuclear palsy pathology. Science Advances. 2022;8(21):eabm5029.
    45. Wada S, Iwamoto K, Okumura H, Hida H, Hiraoka S, Kamei A, Mori D, Yamada K, Ozaki N. Sensory evaluation of the bitterness of asenapine using d-sorbitol pretreatment: Single-blind, placebo-controlled, crossover trial. Bmc Psychiatry. 2023;23(1):159.
    46. Yamaguchi S, Kaminogo K, Tokura T, Kimura H, Kishi S, Yamamoto N, Ichimura N, Toyama N, Koma Y, Kouyama N, Ozaki N, Hibi H. Psychological impact on patients with oral cancer before undergoing resection and free flap reconstruction surgery. Oral Oncology Reports. 2022;3-4:100004.
    47. Yamamoto M, Bagarinao E, Shimamoto M, Iidaka T, Ozaki N. Involvement of cerebellar and subcortical connector hubs in schizophrenia. Neuroimage-Clinical. 2022;35:103140.
    48. Yamasue H, Kojima M, Kuwabara H, Kuroda M, Matsumoto K, Kanai C, Inada N, Owada K, Ochi K, Ono N, Benner S, Wakuda T, Kameno Y, Inoue J, Harada T, Tsuchiya K, Umemura K, Yamauchi A, Ogawa N, Kushima I, Ozaki N, Suyama S, Saito T, Uemura Y, Hamada J, Kano Y, Honda N, Kikuchi S, Seto M, Tomita H, Miyoshi N, Matsumoto M, Kawaguchi Y, Kanai K, Ikeda M, Nakamura I, Isomura S, Hirano Y, Onitsuka T, Kosaka H, Okada T. Effect of a novel nasal oxytocin spray with enhanced bioavailability on autism: A randomized trial. Brain. 2022;145(2):490-499.
    49. Yoshida M, Hasegawa S, Taniguchi M, Mouri A, Suzuki C, Yoshimi A, Mamiya T, Ozaki N, Noda Y. Memantine ameliorates the impairment of social behaviors induced by a single social defeat stress as juveniles. Neuropharmacology. 2022; 217:109208.
  • 2021年
    1. Amare AT, Schubert KO, Hou L, Clark SR, Papiol S, Cearns M, Heilbronner U, Degenhardt F, Tekola-Ayele F, Hsu YH, Shekhtman T, AdIi M, Akula N, Akiyama K, Ardau R, Arias B, Aubry JM, Backlund L, Bhattacharjee K, Bellivier F, Benabarre A, Bengesser S, Biernacka JM, Birner A, Brichant-Petitjean C, Cervantes P, Chen HC, Chillotti C, Cichon S, Cruceanu C, Czerski PM, Dalkner N, Dayer A, Del Zompo M, DePaulo JR, Etain B, Jamain S, Falkai P, Forstner AJ, Frisen L, Frye MA, Fullerton JM, Gard S, Garnham JS, Goes FS, Grigoroiu-Serbanescu M, Grof P, Hashimoto R, Hauser J, Herms S, Hoffmann P, Hofmann A, Jimenez E, Kahn JP, Kassem L, Kuo PH, Kato T, Kelsoe JR, Kittel-Schneider S, Kliwicki S, Konig B, Kusumi I, Laje G, Landen M, Lavebratt C, Leboyer M, Leckband SG, Tortorella A, Manchia M, Martinsson L, McCarthy MJ, McElroy SL, Colom F, Mitjans M, Mondimore FM, Monteleone P, Nievergelt CM, Nothen MM, Novak T, O'Donovan C, Ozaki N, Osby U, Pfennig A, Potash JB, Reif A, Reininghaus E, Rouleau GA, Rybakowski JK, Schalling M, Schofield PR, Schweizer BW, Severino G, Shilling PD, Shimoda K, Simhandl C, Slaney CM, Squassina A, Stamm T, Stopkova P, Maj M, Turecki G, Vieta E, Veeh J, Witt SH, Wright A, Zandi PP, Mitchell PB, Bauer M, Alda M, Rietschel M, McMahon FJ, Schulze TG, Baune BT, Psychiatric Genomics C. Association of polygenic score for major depression with response to lithium in patients with bipolar disorder. Molecular Psychiatry. 2021;26(6):2457-70.
    3. Arioka Y, Shishido E, Kushima I, Suzuki T, Saito R, Aiba A, Mori D, Ozaki N. Chromosome 22q11.2 deletion causes perk-dependent vulnerability in dopaminergic neurons. Ebiomedicine. 2021;63:103138.
    5. Arta RK, Watanabe Y, Inoue E, Nawa Y, Morikawa R, Egawa J, Kushima I, Igeta H, Hoya S, Sugimoto A, Tanra AJ, Ozaki N, Someya T. Resequencing and association analysis of gap43 with autism spectrum disorder and schizophrenia in a japanese population. Research in Autism Spectrum Disorders. 2021;82:101729.
    7. Fujishiro H, Torii Y, Iritani S, Ozaki N. Dopaminergic circuitry in late-life depression and lewy body disease. Psychiatry and Clinical Neurosciences. 2021;75(2):69-70.
    9. Hada K, Wulaer B, Nagai T, Itoh N, Sawahata M, Sobue A, Mizoguchi H, Mori D, Kushima I, Nabeshima T, Ozaki N, Yamada K. Mice carrying a schizophrenia-associated mutation of the arhgap10 gene are vulnerable to the effects of methamphetamine treatment on cognitive function: Association with morphological abnormalities in striatal neurons. Molecular Brain. 2021;14(1):1-17.
    11. Iino K, Toriumi K, Agarie R, Miyashita M, Suzuki K, Horiuchi Y, Niizato K, Oshima K, Imai A, Nagase Y, Kushima I, Koike S, Ikegame T, Jinde S, Nagata E, Washizuka S, Miyata T, Takizawa S, Hashimoto R, Kasai K, Ozaki N, Itokawa M, Arai M. Akr1a1 variant associated with schizophrenia causes exon skipping, leading to loss of enzymatic activity. Frontiers in Genetics. 2021;12.
    13. Ito M, Tokura T, Miyauchi T, Sato (Boku)　A, Kimura H, Tsuchihashi H, Katayama Y. Collaboration of perioperative management in an adult patient with 22 q 11.2 deletion syndrome: A case report. Clinical Case Reports. 2022;10(2):e05489.
    15. Ito T, Hiramatsu Y, Mouri A, Yoshigai T, Takahashi A, Yoshimi A, Mamiya T, Ozaki N, Noda Y. Involvement of pkcpi-sert activity in stress vulnerability of mice exposed to twice-swim stress. Neuroscience Research. 2021;171:83-91.
    17. Iwabuchi T, Takahashi N, Nishimura T, Rahman MS, Harada T, Okumura A, Kuwabara H, Takagai S, Nomura Y, Matsuzaki H, Ozaki N, Tsuchiya KJ. Affiliations expand. Associations Among Maternal Metabolic Conditions, Cord Serum Leptin Levels, and Autistic Symptoms in Children. Front Psychiatry. 2021;12:816196.
    19. Iwamoto K, Iwata M, Kambe D, Imadera Y, Tachibana N, Kajiyama Y, Ando M, Ozaki N. Residual effects of zopiclone on driving performance using a standardized driving simulator among healthy volunteers. Psychopharmacology (Berl). 2022;239(3):841-850.
    21. Iwata M, Iwamoto K, Kitajima I, Nogi T, Onishi K, Kajiyama Y, Nishino I, Ando M, Ozaki N. Validity and reliability of a driving simulator for evaluating the influence of medicinal drugs on driving performance. Psychopharmacology. 2021;238(3):775-86.
    23. Kato T, Nishimura T, Takahashi N, Harada T, Okumura A, Iwabuchi T, Nomura Y, Senju A, Tsuchiya KJ, Takei N. Identification of neurodevelopmental transition patterns from infancy to early childhood and risk factors predicting descending transition. Sci Rep. 2022;12:4822.
    25. Kato Y, Kuwabara H, Okada T, Munesue T, Benner S, Kuroda M, Kojima M, Yassin W, Eriguchi Y, Kameno Y, Murayama C, Nishimura T, Tsuchiya K, Kasai K, Ozaki N, Kosaka H, Yamasue H. Oxytocin-induced increase in n,n-dimethylglycine and time course of changes in oxytocin efficacy for autism social core symptoms. Molecular Autism. 2021;12(1):1-13.
    27. Kawabata K, Bagarinao E, Watanabe H, Maesawa S, Mori D, Hara K, Ohdake R, Masuda M, Ogura A, Kato T, Koyama S, Katsuno M, Wakabayashi T, Kuzuya M, Hoshiyama M, Isoda H, Naganawa S, Ozaki N, Sobue G. Bridging large-scale cortical networks: Integrative and function-specific hubs in the thalamus. Iscience. 2021;24(10):103106.
    29. Kimura H, Mori D, Aleksic B, Ozaki N. Elucidation of molecular pathogenesis and drug development for psychiatric disorders from rare disease-susceptibility variants. Neuroscience Research. 2021;170:24-31.
    31. Le Clerc S, Lombardi L, Baune BT, Amare AT, Schubert KO, Hou LP, Clark SR, Papiol S, Cearns M, Heilbronner U, Degenhardt F, Tekola-Ayele F, Hsu YH, Shekhtman T, Adli M, Akula N, Akiyama K, Ardau R, Arias B, Aubry JM, Backlund L, Bhattacharjee AK, Bellivier F, Benabarre A, Bengesser S, Biernacka JM, Birner A, Brichant-Petitjean C, Cervantes P, Chen HC, Chillotti C, Cichon S, Cruceanu C, Czerski PM, Dalkner N, Dayer A, Del Zompo M, DePaulo JR, Etain B, Jamain S, Falkai P, Forstner AJ, Frisen L, Frye MA, Fullerton JM, Gard S, Garnham JS, Goes FS, Grigoroiu-Serbanescu M, Grof P, Hashimoto R, Hauser J, Herms S, Hofmann P, Jimenez E, Kahn JP, Kassem L, Kuo PH, Kato T, Kelsoe JR, Kittel-Schneider S, Ferensztajn-Rochowiak E, Konig B, Kusumi I, Laje G, Landen M, Lavebratt C, Leckband S, Tortorella A, Manchia M, Martinsson L, McCarthy MJ, McElroy SL, Colom F, Millischer V, Mitjans M, Mondimore FM, Monteleone P, Nievergelt CM, Nothen MM, Novak T, O'Donovan C, Ozaki N, Osby U, Pfennig A, Potash JB, Reif A, Reininghaus E, Rouleau GA, Rybakowski JK, Schalling M, Schofeld PR, Schweizer BW, Severino G, Shilling PD, Shimoda K, Simhandl C, Slaney CM, Pisanu C, Squassina A, Stamm T, Stopkova P, Maj M, Turecki G, Vieta E, Veeh J, Witt SH, Wright A, Zandi PP, Mitchell PB, Bauer M, Alda M, Rietschel M, McMahon FJ, Schulze TG, Boukouaci W, Richard JR, Le Corvoisier P, Barrau C, Zagury JF, Leboyer M, Tamouza R. Hla-drb1 and hla-dqb1 genetic diversity modulates response to lithium in bipolar affective disorders. Scientific Reports. 2021;11(1):1-12.
    33. Lim K, Lam M, Zai C, Tay J, Karlsson N, Deshpande SN, Thelma BK, Ozaki N, Inada T, Sim K, Chong SA, Lencz T, Liu JJ, Lee J. Genome wide study of tardive dyskinesia in schizophrenia. Translational Psychiatry. 2021;11(1):1-10.
    35. Maesawa S, Mizuno S, Bagarinao E, Watanabe H, Kawabata K, Hara K, Ohdake R, Ogura A, Mori D, Nakatsubo D, Isoda H, Hoshiyama M, Katsuno M, Saito R, Ozaki N, Sobue G. Resting state networks related to the maintenance of good cognitive performance during healthy aging. Frontiers in Human Neuroscience. 2021;15:1-18.
    37. Miyata S, Iwamoto K, Banno M, Eguchi J, Kaneko S, Noda A, Ozaki N. Performance of an ambulatory electroencephalogram sleep monitor in patients with psychiatric disorders. Journal of Sleep Research. 2021;30(4):e13273.
    39. Mizutani R, Saiga R, Yamamoto Y, Uesugi M, Takeuchi A, Uesugi K, Terada Y, Suzuki Y, De Andrade V, De Carlo F, Takekoshi S, Inomoto C, Nakamura N, Torii Y, Kushima I, Iritani S, Ozaki N, Oshima K, Itokawa M, Arai M. Structural diverseness of neurons between brain areas and between cases. Translational Psychiatry. 2021;11(1): 1-9.
    41. Nakamura M, Yoshimi A, Mouri A, Tokura T, Kimura H, Kishi S, Miyauchi T, Iwamoto K, Ito M, Sato-Boku A, Ozaki N, Nabeshima T, Noda Y. Duloxetine attenuates pain in association with downregulation of platelet serotonin transporter in patients with burning mouth syndrome and atypical odontalgia. Human Psychopharmacology -Clinical and Experimental. 2022;7(2):e2818.
    43. Nakatochi M, Kushima I, Ozaki N. Implications of germline copy-number variations in psychiatric disorders: Review of large-scale genetic studies. Journal of Human Genetics. 2021;66(1):25-37.
    45. Nishida Y, Ikuta K, Natsume A, Ishihara N, Morikawa M, Kidokoro H, Muramatsu Y, Nonobe N, Ishizuka K, Takeichi T, Kanbe M, Mizuno S, Imagama S, Ozaki N. Establishment of in-hospital clinical network for patients with neurofibromatosis type 1 in nagoya university hospital. Scientific Reports. 2021;11(1): 1-7.
    47. Nishimura T, Kato T, Okumura A, Harada T, Iwabuchi T, Rahman MS, Hirota T, Takahashi M, Adachi M, Kuwabara H, Takagai S, Nomura Y, Takahashi N, Senju A, Tsuchiya KJ. Trajectories of Adaptive Behaviors During Childhood in Females and Males in the General Population. Front Psychiatry. 2022;13:817383.
    49. Nitta A, Izuo N, Hamatani K, Inagaki R, Kusui Y, Fu KQ, Asano T, Torii Y, Habuchi C, Sekiguchi H, Iritani S, Muramatsu S, Ozaki N, Miyamoto Y. Schizophrenia-like behavioral impairments in mice with suppressed expression of piccolo in the medial prefrontal cortex. Journal of Personalized Medicine. 2021;11(7):607.
    51. Noda Y, Soeda K, Uchida M, Goto S, Ito T, Kitagaki S, Mamiya T, Yoshimi A, Ozaki N, Mouri A. Multiple nicotinic acetylcholine receptor subtypes regulate social or cognitive behaviors in mice repeatedly administered phencyclidine. Behavioural Brain Research. 2021;408: 113284.
    53. Ogasawara K, Numata S, Hasegawa N, Nakataki,M, Makinodan M , Ohi K, Takeshima M, Tsuboi T, Hashimoto N, Onitsuka T, Muraoka H, Hori H, Ichihashi K, Inagaki T, Yasui-Furukori N, Hishimoto A, Sugiyama N, Fukumoto K, Nagasawa,T, Matsumoto J, Takaesu Y, Furihata,R, Nemoto K, Nakamura T, Usami M, Miura K, Fujimoto M, Tagata H, Yamada H, Komatsu H, Ochi S, Atake K, Katsumoto E, Kido M, Kishimoto T, Suwa T, Yamamura S, Iga J, Iida H, Inada K, Watanabe K, Hashimoto R. Subjective assessment of participants in education programs on clinical practice guidelines in the field of psychiatry. Neuropsychopharmacology Reports. 2022 Mar 10. doi: 10.1002/npr2.12245
    55. Oh J, Shin HM, Nishimura T, Rahman MS, Takahashi N, Tsuchiya KJ. Perfluorooctanoate and perfluorooctane sulfonate in umbilical cord blood and child cognitive development: Hamamatsu Birth Cohort for Mothers and Children (HBC Study). Environ Int. 2022;163:107215.
    57. Okada I, Iwamoto K, Miyata S, Fujimoto A, Tanaka M, Amano M, Matsuyama N, Taoka T, Naganawa S, Ozaki N. Fluid study: Study protocol for an open-label, single-centre pilot study to investigate the effect of lemborexant on sleep management in japanese subjects aged 50 years and older with insomnia disorder. Bmj Open. 2021;11(11): e054885.
    59. Okuda M, Noda A, Iwamoto K, Nakashima H, Takeda K, Miyata S, Yasuma F, Ozaki N, Shimouchi A. Effects of long sleep time and irregular sleep-wake rhythm on cognitive function in older people. Scientific Reports. 2021;11(1):1-10.
    61. Okuda M, Noda A, Mabuchi S, Iwamoto K, Banno M, Miyata S, Yasuma F, Ozaki N. Sleep fragmentation and working memory in healthy adults. Sleep Science. 2021;14:111-117.
    63. Rahman MS, Takahashi N, Iwabuchi T, Nishimura T, Harada T, Okumura A, Takei N, Nomura Y, Tsuchiya KJ. Elevated risk of attention deficit hyperactivity disorder (ADHD) in Japanese children with higher genetic susceptibility to ADHD with a birth weight under 2000 g. BMC Med. 2021;19:229.
    65. Saiga R, Uesugi M, Takeuchi A, Uesugi K, Suzuki Y, Takekoshi S, Inomoto C, Nakamura N, Torii Y, Kushima I, Iritani S, Ozaki N, Oshima K, Itokawa M, Arai M, Mizutani R. Brain capillary structures of schizophrenia cases and controls show a correlation with their neuron structures. Scientific Reports. 2021;11(1):1-9.
    67. Saito R, Miyoshi C, Koebis M, Kushima I, Nakao K, Mori D, Ozaki N, Funato H, Yanagisawa M, Aiba A. Two novel mouse models mimicking minor deletions in 22q11.2 deletion syndrome revealed the contribution of each deleted region to psychiatric disorders. Molecular Brain. 2021;14(1):1-15.
    69. Sato A, Kimura H, Tokura T, Umemura E, Miyauchi T, Ito M, Kishi S, Ogi N, Tonoike T, Ozaki N, Nakano Y, Okuda M. Evaluation of patients suffered from burning mouth syndrome and persistent idiopathic facial pain using japanese version paindetect questionnaire and depression scales. Journal of Dental Sciences. 2021;16(1):131-136.
    71. Sato M, Okada T, Morikawa M, Nakamura Y, Yamauchi A, Ando M, Ozaki N. Validation and factor analysis of the parental bonding instrument in japanese pregnant women. Scientific Reports. 2021;11(1):1-10.
    73. Schubert KO, Thalamuthu A, Amare AT, Frank J, Streit F, Adl M, Akula N, Akiyama K, Ardau R, Arias B, Aubry JM, Backlund L, Bhattacharjee AK, Bellivier F, Benabarre A, Bengesser S, Biernacka JM, Birner A, Marie-Claire C, Cearns M, Cervantes P, Chen HC, Chillotti C, Cichon S, Clark SR, Cruceanu C, Czerski PM, Dalkner N, Dayer A, Degenhardt F, Del Zompo M, DePaulo JR, Etain B, Falkai P, Forstner AJ, Frisen L, Frye MA, Fullerton JM, Gard S, Garnham JS, Goes FS, Grigoroiu-Serbanescu M, Grof P, Hashimoto R, Hauser J, Heilbronner U, Herms S, Hoffmann P, Hou LP, Hsu YH, Jamain S, Jimenez E, Kahn JP, Kassem L, Kuo PH, Kato T, Kelsoe J, Kittel-Schneider S, Ferensztajn-Rochowiak E, Konig B, Kusumi I, Laje G, Landen M, Lavebratt C, Leboyer M, Leckband SG, Maj M, Manchia M, Martinsson L, McCarthy MJ, McElroy S, Colom F, Mitjans M, Mondimore FM, Monteleone P, Nievergelt CM, Nothen MM, Novak T, O'Donovan C, Ozaki N, Osby U, Papiol S, Pfennig A, Pisanu C, Potash JB, Reif A, Reininghaus E, Rouleau GA, Rybakowski JK, Schalling M, Schofield PR, Schweizer BW, Severino G, Shekhtman T, Shilling PD, Shimoda K, Simhandl C, Slaney CM, Squassina A, Stamm T, Stopkova P, Tekola-Ayele F, Tortorella A, Turecki G, Veeh J, Vieta E, Witt SH, Roberts G, Zandi PP, Alda M, Bauer M, McMahon FJ, Mitchell PB, Schulze TG, Rietschel M, Baune BT, Psychiat Genomics C. Combining schizophrenia and depression polygenic risk scores improves the genetic prediction of lithium response in bipolar disorder patients. Translational Psychiatry. 2021;11(1):1-8.
    75. Sekiguchi H, Fujishiro H, Torii Y, Iritani S, Ozaki N. Can we identify prodromal dementia with lewy bodies in late-life depression? Psychiatry and Clinical Neurosciences. 2021;75(3):113-114.
    77. Shizuku M, Kimura H, Kamei H, Kishi S, Tokura T, Kurata N, Jobara K, Yoshizawa A, Tsuboi C, Yamaguchi N, Kato M, Kawai K, Yamashiki M, Kanai E, Ishizuka K, Ozaki N, Ogura Y. Psychosocial characteristics of alcoholic and non-alcoholic liver disease recipient candidates in liver transplantation: A prospective observational study. Bmc Gastroenterology. 2021;21(1):1-10.
    79. Stone W, Nunes A, Akiyama K, Akula N, Ardau R, Aubry JM, Backlund L, Bauer M, Bellivier F, Cervantes P, Chen HC, Chillotti C, Cruceanu C, Dayer A, Degenhardt F, Del Zompo M, Forstner AJ, Frye M, Fullerton JM, Grigoroiu-Serbanescu M, Grof P, Hashimoto R, Hou LP, Jimenez E, Kato T, Kelsoe J, Kittel-Schneider S, Kuo PH, Kusumi I, Lavebratt C, Manchia M, Martinsson L, Mattheisen M, McMahon FJ, Millischer V, Mitchell PB, Nothen MM, O'Donovan C, Ozaki N, Pisanu C, Reif A, Rietschel M, Rouleau G, Rybakowski J, Schalling M, Schofield PR, Schulze TG, Severino G, Squassina A, Veeh J, Vieta E, Trappenberg T, Alda M. Prediction of lithium response using genomic data. Scientific Reports. 2021;11(1):1-10.
    81. Tachibana M, Inada T, Ichida M, Kojima S, Arai T, Naito K, Ozaki N. Significant decrease in delirium referrals after changing hypnotic from benzodiazepine to suvorexant. Psychogeriatrics. 2021;21(3):324-332.
    83. Tachibana M, Inada T, Ichida M, Kojima S, Shioya M, Wakayama K, Ozaki N. Factors associated with the severity of delirium. Human Psychopharmacology-Clinical and Experimental. 2021;36(5):e2787.
    85. Tachibana M, Inada T, Ichida M, Ozaki N. Risk factors for inducing violence in patients with delirium. Brain and Behavior. 2021;11(8):e2276.
    87. Tachibana M, Inada T, Ichida M, Ozaki N. Factors affecting hallucinations in patients with delirium. Scientific Reports. 2021;11(1):1-6.
    89. Takahashi N, Okumura A, Nishimura T, Harada T, Iwabuchi T, Rahman MS, Tsuchiya KJ. Exploration of Sleep Parameters, Daytime Hyperactivity/Inattention, and Attention-Deficit/Hyperactivity Disorder Polygenic Risk Scores of Children in a Birth Cohort in Japan. JAMA Netw Open. 2022;5:e2141768.
    91. Takahashi N, Nishimura T, Harada T, Okumura A, Iwabuchi T, Rahman MS, Kuwabara H, Takagai S, Nomura Y, Takei N, Tsuchiya KJ. Association Between Genetic Risks for Obesity and Working Memory in Children. Front Neurosci. 2021;15:749230.
    93. Takahashi N, Ishizuka K, Inada T. Peripheral biomarkers of attention-deficit hyperactivity disorder: Current status and future perspective. J Psychiatr Res. 2021;137:465-70.
    95. Tsuneura Y, Sawahata M, Itoh N, Miyajima R, Mori D, Kohno T, Hattori M, Sobue A, Nagai T, Mizoguchi H, Nabeshima T, Ozaki N, Yamada K. Analysis of reelin signaling and neurodevelopmental trajectory in primary cultured cortical neurons with reln deletion identified in schizophrenia. Neurochemistry International. 2021;144:104954.
    97. Uchida M, Noda Y, Hasegawa S, Hida H, Taniguchi M, Mouri A, Yoshimi A, Nabeshima T, Yamada K, Aida T, Tanaka K, Ozaki N. Early postnatal inhibition of glast causes abnormalities of psychobehaviors and neuronal morphology in adult mice. Neurochemistry International. 2021;150:105177.
    99. Yoshikawa A, Kushima I, Miyashita M, Toriumi K, Suzuki K, Horiuchi Y, Kawaji H, Takizawa S, Ozaki N, Itokawa M, Arai M. Dysregulation of post-transcriptional modification by copy number variable micrornas in schizophrenia with enhanced glycation stress. Translational Psychiatry. 2021;11(1):1-11.
  • ～2020年
    1. Amare AT, Schubert KO, Hou L, Clark SR, Papiol S, Cearns M, Heilbronner U, Degenhardt F, Tekola-Ayele F, Hsu YH, Shekhtman T, Adli M, Akula N, Akiyama K, Ardau R, Arias B, Aubry JM, Backlund L, Bhattacharjee AK, Bellivier F, Benabarre A, Bengesser S, Biernacka JM, Birner A, Brichant-Petitjean C, Cervantes P, Chen HC, Chillotti C, Cichon S, Cruceanu C, Czerski PM, Dalkner N, Dayer A, Del Zompo M, DePaulo JR, Étain B, Jamain S, Falkai P, Forstner AJ, Frisen L, Frye MA, Fullerton JM, Gard S, Garnham JS, Goes FS, Grigoroiu-Serbanescu M, Grof P, Hashimoto R, Hauser J, Herms S, Hoffmann P, Hofmann A, Jiménez E, Kahn JP, Kassem L, Kuo PH, Kato T, Kelsoe JR, Kittel-Schneider S, Kliwicki S, König B, Kusumi I, Laje G, Landén M, Lavebratt C, Leboyer M, Leckband SG, Tortorella A, Manchia M, Martinsson L, McCarthy MJ, McElroy SL, Colom F, Mitjans M, Mondimore FM, Monteleone P, Nievergelt CM, Nöthen MM, Novák T, O'Donovan C, Ozaki N, Ösby U, Pfennig A, Potash JB, Reif A, Reininghaus E, Rouleau GA, Rybakowski JK, Schalling M, Schofield PR, Schweizer BW, Severino G, Shilling PD, Shimoda K, Simhandl C, Slaney CM, Squassina A, Stamm T, Stopkova P, Maj M, Turecki G, Vieta E, Veeh J, Witt SH, Wright A, Zandi PP, Mitchell PB, Bauer M, Alda M, Rietschel M, McMahon FJ, Schulze TG, Baune BT. Association of polygenic score for major depression with response to lithium in patients with bipolar disorder. Molecular psychiatry. 2020. https://doi.org/10.1038/s41380-020-0689-5
    2. Arioka Y, Hirata A, Kushima I, Aleksic B, Mori D, Ozaki N. Characterization of a schizophrenia patient with a rare reln deletion by combining genomic and patient-derived cell analyses. Schizophrenia research. 2020;216:511-5.
    3. Arioka Y, Shishido E, Kushima I, Mori D, Ozaki N. Cell body shape and directional movement stability in human-induced pluripotent stem cell-derived dopaminergic neurons. Scientific reports. 2020;10(1):5820.
    4. Bagarinao E, Watanabe H, Maesawa S, Mori D, Hara K, Kawabata K, Ohdake R, Masuda M, Ogura A, Kato T, Koyama S, Katsuno M, Wakabayashi T, Kuzuya M, Hoshiyama M, Isoda H, Naganawa S, Ozaki N, Sobue G. Identifying the brain's connector hubs at the voxel level using functional connectivity overlap ratio. NeuroImage. 2020;222:117241.
    5. Bagarinao E, Watanabe H, Maesawa S, Mori D, Hara K, Kawabata K, Yoneyama N, Ohdake R, Imai K, Masuda M, Yokoi T, Ogura A, Taoka T, Koyama S, Tanabe HC, Katsuno M, Wakabayashi T, Kuzuya M, Hoshiyama M, Isoda H, Naganawa S, Ozaki N, Sobue G. Aging impacts the overall connectivity strength of regions critical for information transfer among brain networks. Frontiers in aging neuroscience. 2020;12:592469.
    6. Choy SW, Bagarinao E, Watanabe H, Ho ETW, Maesawa S, Mori D, Hara K, Kawabata K, Yoneyama N, Ohdake R, Imai K, Masuda M, Yokoi T, Ogura A, Taoka T, Koyama S, Tanabe HC, Katsuno M, Wakabayashi T, Kuzuya M, Hoshiyama M, Isoda H, Naganawa S, Ozaki N, Sobue G. Changes in white matter fiber density and morphology across the adult lifespan: A cross-sectional fixel-based analysis. Human brain mapping. 2020;41(12):3198-211.
    7. Ishizuka K, Yoshida T, Kawabata T, Imai A, Mori H, Kimura H, Inada T, Okahisa Y, Egawa J, Usami M, Kushima I, Morikawa M, Okada T, Ikeda M, Branko A, Mori D, Someya T, Iwata N, Ozaki N. Functional characterization of rare nrxn1 variants identified in autism spectrum disorders and schizophrenia. Journal of neurodevelopmental disorders. 2020;12(1):25.
    8. Ito T, Hiramatsu Y, Uchida M, Yoshimi A, Mamiya T, Mouri A, Ozaki N, Noda Y. Involvement of protein kinase c beta1-serotonin transporter system dysfunction in emotional behaviors in stressed mice. Neurochemistry international. 2020;140:104826.
    9. Ito Y, Maesawa S, Bagarinao E, Okai Y, Nakatsubo D, Yamamoto H, Kidokoro H, Usui N, Natsume J, Hoshiyama M, Wakabayashi T, Sobue G, Ozaki N. Subsecond eeg-fmri analysis for presurgical evaluation in focal epilepsy. Journal of neurosurgery. 2020:1-10.
    10. Itokawa M, Oshima K, Arai M, Torii Y, Kushima I, Iritani S, Ozaki N, Saiga R, Mizutani R. Cutting-edge morphological studies of post-mortem brains of patients with schizophrenia and potential applications of x-ray nanotomography (nano-ct). Psychiatry and clinical neurosciences. 2020;74(3):176-82.
    11. Kato K, Noda A, Yasuma F, Matsubara Y, Miyata S, Iwamoto K, Miyazaki S, Ozaki N. Effects of sleep-disordered breathing and hypertension on cognitive function in elderly adults. Clinical and experimental hypertension (New York, NY : 1993). 2020;42(3):250-6.
    12. Kato S, Bagarinao E, Isoda H, Koyama S, Watanabe H, Maesawa S, Mori D, Hara K, Katsuno M, Hoshiyama M, Naganawa S, Ozaki N, Sobue G. Effects of head motion on the evaluation of age-related brain network changes using resting state functional mri. Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine. 2020.
    13. Kimura H, Mori D, Aleksic B, Ozaki N. Elucidation of molecular pathogenesis and drug development for psychiatric disorders from rare disease-susceptibility variants. Neuroscience research. 2020.
    14. Koshiyama D, Fukunaga M, Okada N, Morita K, Nemoto K, Usui K, Yamamori H, Yasuda Y, Fujimoto M, Kudo N, Azechi H, Watanabe Y, Hashimoto N, Narita H, Kusumi I, Ohi K, Shimada T, Kataoka Y, Yamamoto M, Ozaki N, Okada G, Okamoto Y, Harada K, Matsuo K, Yamasue H, Abe O, Hashimoto R, Takahashi T, Hori T, Nakataki M, Onitsuka T, Holleran L, Jahanshad N, van Erp TGM, Turner J, Donohoe G, Thompson PM, Kasai K, Hashimoto R. White matter microstructural alterations across four major psychiatric disorders: Mega-analysis study in 2937 individuals. Molecular psychiatry. 2020;25(4):883-95.
    15. Kubota C, Inada T, Nakamura Y, Shiino T, Ando M, Aleksic B, Yamauchi A, Morikawa M, Okada T, Ohara M, Sato M, Murase S, Goto S, Kanai A, Ozaki N. Validation and factor structure of the japanese version of the inventory to diagnose depression, lifetime version for pregnant women. PloS one. 2020;15(6):e0234240.
    16. Kubota C, Inada T, Shiino T, Ando M, Sato M, Nakamura Y, Yamauchi A, Morikawa M, Okada T, Ohara M, Aleksic B, Murase S, Goto S, Kanai A, Ozaki N. The risk factors predicting suicidal ideation among perinatal women in japan. Frontiers in psychiatry. 2020;11:441.
    17. Lim ET, Uddin M, De Rubeis S, Chan Y, Kamumbu AS, Zhang X, D'Gama AM, Kim SN, Hill RS, Goldberg AP, Poultney C, Minshew NJ, Kushima I, Aleksic B, Ozaki N, Parellada M, Arango C, Penzol MJ, Carracedo A, Kolevzon A, Hultman CM, Weiss LA, Fromer M, Chiocchetti AG, Freitag CM, Church GM, Scherer SW, Buxbaum JD, Walsh CA. Publisher correction: Rates, distribution and implications of postzygotic mosaic mutations in autism spectrum disorder. Nature neuroscience. 2020;23(9):1176.
    18. Miyata S, Iwamoto K, Banno M, Eguchi J, Kaneko S, Noda A, Ozaki N. Performance of an ambulatory electroencephalogram sleep monitor in patients with psychiatric disorders. Journal of sleep research. 2020:e13273.
    19. Miyata S, Otake H, Ando M, Okuda M, Fujishiro H, Iwamoto K, Noda A, Sone M, Ozaki N. Patient characteristics affecting accurate detection of sleep apnea using a bed sheet-type portable monitor. Sleep & breathing = Schlaf & Atmung. 2020;24(2):783-90.
    20. Mukoyama N, Nishio N, Kimura H, Kishi S, Tokura T, Kimura H, Hiramatsu M, Maruo T, Tsuzuki H, Fujii M, Iwami K, Takanari K, Kamei Y, Ozaki N, Sone M, Fujimoto Y. Prospective evaluation of health-related quality of life in patients undergoing anterolateral craniofacial resection with orbital exenteration. Journal of neurological surgery Part B, Skull base. 2020;81(5):585-93.
    21. Nakamura Y, Okada T, Morikawa M, Yamauchi A, Sato M, Ando M, Ozaki N. Perinatal depression and anxiety of primipara is higher than that of multipara in japanese women. Scientific reports. 2020;10(1):17060.
    22. Noda Y, Uchida M, Mouri A, Yamada S, Goto S, Kitagaki S, Mamiya T, Kushima I, Arioka Y, Ozaki N, Yoshimi A. Involvement of nicotinic acetylcholine receptors in behavioral abnormalities and psychological dependence in schizophrenia-like model mice. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. 2020;41:92-105.
    23. Saito R, Koebis M, Nagai T, Shimizu K, Liao J, Wulaer B, Sugaya Y, Nagahama K, Uesaka N, Kushima I, Mori D, Maruyama K, Nakao K, Kurihara H, Yamada K, Kano M, Fukada Y, Ozaki N, Aiba A. Comprehensive analysis of a novel mouse model of the 22q11.2 deletion syndrome: A model with the most common 3.0-mb deletion at the human 22q11.2 locus. Translational psychiatry. 2020;10(1):35.
    24. Sakurai M, Yamamoto Y, Kanayama N, Hasegawa M, Mouri A, Takemura M, Matsunami H, Miyauchi T, Tokura T, Kimura H, Ito M, Umemura E, Boku AS, Nagashima W, Tonoike T, Kurita K, Ozaki N, Nabeshima T, Saito K. Serum metabolic profiles of the tryptophan-kynurenine pathway in the high risk subjects of major depressive disorder. Scientific reports. 2020;10(1):1961.
    25. Sawahata M, Mori D, Arioka Y, Kubo H, Kushima I, Kitagawa K, Sobue A, Shishido E, Sekiguchi M, Kodama A, Ikeda R, Aleksic B, Kimura H, Ishizuka K, Nagai T, Kaibuchi K, Nabeshima T, Yamada K, Ozaki N. Generation and analysis of novel reln-deleted mouse model corresponding to exonic reln deletion in schizophrenia. Psychiatry and clinical neurosciences. 2020;74(5):318-27.
    26. Sekiguchi M, Sobue A, Kushima I, Wang C, Arioka Y, Kato H, Kodama A, Kubo H, Ito N, Sawahata M, Hada K, Ikeda R, Shinno M, Mizukoshi C, Tsujimura K, Yoshimi A, Ishizuka K, Takasaki Y, Kimura H, Xing J, Yu Y, Yamamoto M, Okada T, Shishido E, Inada T, Nakatochi M, Takano T, Kuroda K, Amano M, Aleksic B, Yamomoto T, Sakuma T, Aida T, Tanaka K, Hashimoto R, Arai M, Ikeda M, Iwata N, Shimamura T, Nagai T, Nabeshima T, Kaibuchi K, Yamada K, Mori D, Ozaki N. Arhgap10, which encodes rho gtpase-activating protein 10, is a novel gene for schizophrenia risk. Translational psychiatry. 2020;10(1):247.
    27. Shizuku M, Kamei H, Kimura H, Kurata N, Jobara K, Yoshizawa A, Ishizuka K, Okada A, Kishi S, Ozaki N, Ogura Y. Clinical features and long-term outcomes of living donors of liver transplantation who developed psychiatric disorders. Annals of transplantation. 2020;25:e918500.
    28. Suzuki T, Suzuki T, Raveau M, Miyake N, Sudo G, Tsurusaki Y, Watanabe T, Sugaya Y, Tatsukawa T, Mazaki E, Shimohata A, Kushima I, Aleksic B, Shiino T, Toyota T, Iwayama Y, Nakaoka K, Ohmori I, Sasaki A, Watanabe K, Hirose S, Kaneko S, Inoue Y, Yoshikawa T, Ozaki N, Kano M, Shimoji T, Matsumoto N, Yamakawa K. A recurrent pja1 variant in trigonocephaly and neurodevelopmental disorders. Annals of clinical and translational neurology. 2020;7(7):1117-31.
    29. Taniguchi S, Ninomiya K, Kushima I, Saito T, Shimasaki A, Sakusabe T, Momozawa Y, Kubo M, Kamatani Y, Ozaki N, Ikeda M, Iwata N. Polygenic risk scores in schizophrenia with clinically significant copy number variants. Psychiatry and clinical neurosciences. 2020;74(1):35-9.
    30. Torii Y, Iritani S, Marui T, Sekiguchi H, Habuchi C, Fujishiro H, Kushima I, Oshima K, Niizato K, Hayashida S, Masaki K, Kira JI, Yoshida M, Ozaki N. Morphological alteration of myelin-oligodendrocytes in a schizophrenic patient with 22q11.2 deletion syndrome: An autopsy study. Schizophrenia research. 2020;223:353-5.
    31. Torii Y, Iritani S, Sekiguchi H, Habuchi C, Fujishiro H, Kushima I, Kawakami I, Itokawa M, Arai M, Hayashida S, Masaki K, Kira JI, Kawashima K, Ozaki N. The accumulation of advanced glycation end-products in a schizophrenic patient with a glyoxalase 1 frameshift mutation: An autopsy study. Schizophrenia research. 2020;223:356-8.
    32. Yamamoto M, Bagarinao E, Kushima I, Takahashi T, Sasabayashi D, Inada T, Suzuki M, Iidaka T, Ozaki N. Support vector machine-based classification of schizophrenia patients and healthy controls using structural magnetic resonance imaging from two independent sites. PloS one. 2020;15(11):e0239615.
    33. Yamasue H, Okada T, Munesue T, Kuroda M, Fujioka T, Uno Y, Matsumoto K, Kuwabara H, Mori D, Okamoto Y, Yoshimura Y, Kawakubo Y, Arioka Y, Kojima M, Yuhi T, Owada K, Yassin W, Kushima I, Benner S, Ogawa N, Eriguchi Y, Kawano N, Uemura Y, Yamamoto M, Kano Y, Kasai K, Higashida H, Ozaki N, Kosaka H. Effect of intranasal oxytocin on the core social symptoms of autism spectrum disorder: A randomized clinical trial. Molecular psychiatry. 2020;25(8):1849-58.
    34. Yu Y, Chaulagain A, Pedersen SA, Lydersen S, Leventhal BL, Szatmari P, Aleksic B, Ozaki N, Skokauskas N. Pharmacotherapy of restricted/repetitive behavior in autism spectrum disorder:A systematic review and meta-analysis. BMC psychiatry. 2020;20(1):121.
    35. Yuka K, Nishizawa D, Hasegawa J, Uno K, Miyanishi H, Ujike H, Ozaki N, Inada T, Iwata N, Sora I, Iyo M, Yamada M, Kondo N, Won MJ, Naruse N, Uehara-Aoyama K, Ikeda K, Nitta A. A single medical marker for diagnosis of methamphetamine addiction - DNA methylation of shati/nat8l promoter sites from patient blood. Current pharmaceutical design. 2020;26(2):260-4.
    36. Baba M, Yokoyama K, Seiriki K, Naka Y, Matsumura K, Kondo M, Yamamoto K, Hayashida M, Kasai A, Ago Y, Nagayasu K, Hayata-Takano A, Takahashi A, Yamaguchi S, Mori D, Ozaki N, Yamamoto T, Takuma K, Hashimoto R, Hashimoto H, Nakazawa T. Psychiatric-disorder-related behavioral phenotypes and cortical hyperactivity in a mouse model of 3q29 deletion syndrome. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2019;44(12):2125-35.
    37. Bagarinao E, Watanabe H, Maesawa S, Mori D, Hara K, Kawabata K, Yoneyama N, Ohdake R, Imai K, Masuda M, Yokoi T, Ogura A, Taoka T, Koyama S, Tanabe HC, Katsuno M, Wakabayashi T, Kuzuya M, Ozaki N, Hoshiyama M, Isoda H, Naganawa S, Sobue G. Reorganization of brain networks and its association with general cognitive performance over the adult lifespan. Scientific reports. 2019;9(1):11352.
    38. Fujishiro H, Kimura H, Nakamura T, Torii Y, Iritani S, Ozaki N. Hypochondriasis in the elderly and lewy body disease. Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society. 2019;19(5):516-8.
    39. Fujishiro H, Okuda M, Iwamoto K, Miyata S, Torii Y, Iritani S, Ozaki N. Clinical profiles of late-onset psychiatric patients exhibiting incidental rem sleep without atonia. Journal of neural transmission (Vienna, Austria : 1996). 2019;126(8):1095-104.
    40. Hasegawa S, Yoshimi A, Mouri A, Uchida Y, Hida H, Mishina M, Yamada K, Ozaki N, Nabeshima T, Noda Y. Acute administration of ketamine attenuates the impairment of social behaviors induced by social defeat stress exposure as juveniles via activation of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (ampa) receptors. Neuropharmacology. 2019;148:107-16.
    41. Hayakawa N, Tanaka S, Hirata N, Ogino S, Ozaki N. A battery of self-screening instruments and self-reported body frame could not detect eating disorders among college students. BMC research notes. 2019;12(1):613.
    42. Hirano M, Iritani S, Fujishiro H, Torii Y, Habuchi C, Sekiguchi H, Yoshida M, Ozaki N. Clinicopathological differences between the motor onset and psychiatric onset of huntington's disease, focusing on the nucleus accumbens. Neuropathology : official journal of the Japanese Society of Neuropathology. 2019;39(5):331-41.
    43. Ikeda M, Takahashi A, Kamatani Y, Momozawa Y, Saito T, Kondo K, Shimasaki A, Kawase K, Sakusabe T, Iwayama Y, Toyota T, Wakuda T, Kikuchi M, Kanahara N, Yamamori H, Yasuda Y, Watanabe Y, Hoya S, Aleksic B, Kushima I, Arai H, Takaki M, Hattori K, Kunugi H, Okahisa Y, Ohnuma T, Ozaki N, Someya T, Hashimoto R, Yoshikawa T, Kubo M, Iwata N. Genome-wide association study detected novel susceptibility genes for schizophrenia and shared trans-populations/diseases genetic effect. Schizophrenia bulletin. 2019;45(4):824-34.
    44. Ishii T, Ishikawa M, Fujimori K, Maeda T, Kushima I, Arioka Y, Mori D, Nakatake Y, Yamagata B, Nio S, Kato TA, Yang N, Wernig M, Kanba S, Mimura M, Ozaki N, Okano H. In vitro modeling of the bipolar disorder and schizophrenia using patient-derived induced pluripotent stem cells with copy number variations of pcdh15 and reln. eNeuro. 2019;6(5).
    45. Iwata M, Iwamoto K, Omura T, Ando M, Ozaki N. Protocol for the development and validation of a driving simulator for evaluating the influence of drugs on driving performance. Medicine. 2019;98(8):e14613.
    46. Kato H, Ozaki N. [the considerations for diagnosis of autism spectrum disorders and its pathogenic mechanisms]. Rinsho shinkeigaku = Clinical neurology. 2019;59(1):13-20.
    47. Kawakubo H, Matsui Y, Kushima I, Ozaki N, Shimamura T. A network of networks approach for modeling interconnected brain tissue-specific networks. Bioinformatics (Oxford, England). 2019;35(17):3092-101.
    48. Kubota C, Inada T, Shiino T, Ando M, Aleksic B, Yamauchi A, Sato M, Ohara M, Murase S, Morikawa M, Nakamura Y, Okada T, Goto S, Kanai A, Ozaki N. Relation between perinatal depressive symptoms, harm avoidance, and a history of major depressive disorder: A cohort study of pregnant women in japan. Frontiers in psychiatry. 2019;10:515.
    49. Matsubara T, Hayashi K, Wakatsuki K, Abe M, Ozaki N, Yamanaka A, Mizumura K, Taguchi T. Thin-fibre receptors expressing acid-sensing ion channel 3 contribute to muscular mechanical hypersensitivity after exercise. European journal of pain (London, England). 2019;23(10):1801-13.
    50. Miyata S, Noda A, Kawai S, Honda K, Iwamoto K, Ozaki N, Miyazaki S, Kondo T. Delayed sleep/wake rhythm and excessive daytime sleepiness correlate with decreased daytime brain activity during cognitive task in university students. Biological and rhythm research, 2019; 50(2)：171-179.
    51. Miyauchi T, Tokura T, Kimura H, Ito M, Umemura E, Sato Boku A, Nagashima W, Tonoike T, Yamamoto Y, Saito K, Kurita K, Ozaki N. Effect of antidepressant treatment on plasma levels of neuroinflammation-associated molecules in patients with somatic symptom disorder with predominant pain around the orofacial region. Human psychopharmacology. 2019;34(4):e2698.
    52. Mizutani R, Saiga R, Takeuchi A, Uesugi K, Terada Y, Suzuki Y, De Andrade V, De Carlo F, Takekoshi S, Inomoto C, Nakamura N, Kushima I, Iritani S, Ozaki N, Ide S, Ikeda K, Oshima K, Itokawa M, Arai M. Three-dimensional alteration of neurites in schizophrenia. Translational psychiatry. 2019;9(1):85.
    53. Nakamura Y, Nakatochi M, Kunimoto S, Okada T, Aleksic B, Toyama M, Shiino T, Morikawa M, Yamauchi A, Yoshimi A, Furukawa-Hibi Y, Nagai T, Ohara M, Kubota C, Yamada K, Ando M, Ozaki N. Methylation analysis for postpartum depression: A case control study. BMC psychiatry. 2019;19(1):190.
    54. Noda A, Yasuma F, Miyata S, Iwamoto K, Yasuda Y, Ozaki N. Sleep fragmentation and risk of automobile accidents in patients with obstructive sleep apnea. Health 2019; 11(2): 171-181.
    55. Owada K, Okada T, Munesue T, Kuroda M, Fujioka T, Uno Y, Matsumoto K, Kuwabara H, Mori D, Okamoto Y, Yoshimura Y, Kawakubo Y, Arioka Y, Kojima M, Yuhi T, Yassin W, Kushima I, Benner S, Ogawa N, Kawano N, Eriguchi Y, Uemura Y, Yamamoto M, Kano Y, Kasai K, Higashida H, Ozaki N, Kosaka H, Yamasue H. Quantitative facial expression analysis revealed the efficacy and time course of oxytocin in autism. Brain : a journal of neurology. 2019;142(7):2127-36.
    56. Park SC, Oh HS, Tripathi A, Kallivayalil RA, Avasthi A, Grover S, Tanra AJ, Kanba S, Kato TA, Inada T, Chee KY, Chong MY, Lin SK, Sim K, Xiang YT, Tan CH, Javed A, Sartorius N, Shinfuku N, Park YC. Cannabis use correlates with aggressive behavior and long-acting injectable antipsychotic treatment in asian patients with schizophrenia. Nordic journal of psychiatry. 2019;73(6):323-30.
    57. Sato N, Kimura H, Adachi Y, Nishio N, Ando M, Tokura T, Nagashima W, Kishi S, Yamauchi A, Yoshida K, Hiramatsu M, Fujimoto Y, Ozaki N. Exploration of coping styles in male patients with head and neck cancer: A prospective cohort study. Nagoya journal of medical science. 2019;81(2):249-58.
    58. Shishido E, Ogawa S, Miyata S, Yamamoto M, Inada T, Ozaki N. Application of eye trackers for understanding mental disorders: Cases for schizophrenia and autism spectrum disorder. Neuropsychopharmacology reports. 2019;39(2):72-7.
    59. Takeuchi S, Hida H, Uchida M, Naruse R, Yoshimi A, Kitagaki S, Ozaki N, Noda Y. Blonanserin ameliorates social deficit through dopamine-d3 receptor antagonism in mice administered phencyclidine as an animal model of schizophrenia. Neurochemistry international. 2019;128:127-34.
    60. Tanaka S, Oya-Ito T, Murakami Y, Saito K, Furuta S, Yu Y, Imaeda M, Kunimoto S, Ozaki N. Decline of plasma concentrations of interleukin-18 in severely malnourished patients with anorexia nervosa: Exploratory analysis. Nutrients. 2019;11(3).
    61. Teshigawara T, Mouri A, Kubo H, Nakamura Y, Shiino T, Okada T, Morikawa M, Nabeshima T, Ozaki N, Yamamoto Y, Saito K. Changes in tryptophan metabolism during pregnancy and postpartum periods: Potential involvement in postpartum depressive symptoms. Journal of affective disorders. 2019;255:168-76.
    62. Uchida M, Hida H, Mori K, Yoshimi A, Kitagaki S, Yamada K, Hiraoka Y, Aida T, Tanaka K, Ozaki N, Noda Y. Erratum to \"functional roles of the glial glutamate transporter (glast) in emotional and cognitive abnormalities of mice after repeated phencyclidine administration\" [european neuropsychopharmacology (2019) 29, 914-924]. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. 2019;29(9):1063-4.
    63. Uchida M, Hida H, Mori K, Yoshimi A, Kitagaki S, Yamada K, Hiraoka Y, Aida T, Tanaka K, Ozaki N, Noda Y. Functional roles of the glial glutamate transporter (glast) in emotional and cognitive abnormalities of mice after repeated phencyclidine administration. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. 2019;29(8):914-24.
    64. Ueda K, Kiyota A, Tsuchida M, Okazaki M, Ozaki N. Successful treatment of myxedema coma with a combination of levothyroxine and liothyronine. Endocrine journal. 2019;66(5):469-74.
    65. Umemura E, Tokura T, Ito M, Kobayashi Y, Tachibana M, Miyauchi T, Tonoike T, Nagashima W, Kimura H, Arao M, Sato Boku A, Ozaki N, Kurita K. Oral medicine psychiatric liaison clinic: Study of 1202 patients attending over an 18-year period. International journal of oral and maxillofacial surgery. 2019;48(5):644-50.
    66. Weidle B, Chaulagain A, Stensen K, Aleksic B, Skokauskas N, Inada T. Drug-induced extrapyramidal symptoms scale of the norwegian version: Inter-rater and test-retest reliability. Nordic journal of psychiatry. 2019;73(8):546-50.
    67. Yoshimi A, Yamada S, Kunimoto S, Aleksic B, Hirakawa A, Ohashi M, Matsumoto Y, Hada K, Itoh N, Arioka Y, Kimura H, Kushima I, Nakamura Y, Shiino T, Mori D, Tanaka S, Hamada S, Noda Y, Nagai T, Yamada K, Ozaki N. Author correction: Proteomic analysis of lymphoblastoid cell lines from schizophrenic patients. Translational psychiatry. 2019;9(1):146.
    68. Yoshimi A, Yamada S, Kunimoto S, Aleksic B, Hirakawa A, Ohashi M, Matsumoto Y, Hada K, Itoh N, Arioka Y, Kimura H, Kushima I, Nakamura Y, Shiino T, Mori D, Tanaka S, Hamada S, Noda Y, Nagai T, Yamada K, Ozaki N. Proteomic analysis of lymphoblastoid cell lines from schizophrenic patients. Translational psychiatry. 2019;9(1):126.
    69. Arioka Y, Hirata A, Kushima I, Aleksic B, Mori D, Ozaki N. Characterization of a schizophrenia patient with a rare reln deletion by combining genomic and patient-derived cell analyses. Schizophrenia research. 2019. In press.
    70. Miyata S, Otake H, Ando M, Okuda M, Fujishiro H, Iwamoto K, Noda A, Sone M, Ozaki N. Patient characteristics affecting accurate detection of sleep apnea using a bed sheet-type portable monitor. Sleep & breathing. 2019. In Press.
    71. Mukoyama N, Nishio N, Kimura H, Kishi S, Tokura T, Kimura H, Hiramatsu M, Maruo T, Tsuzuki H, Fujii M, Iwami K, Takanari K, Kamei Y, Ozaki N, Sone M, Fujimoto Y. Prospective evaluation of health-related quality of life in patients undergoing anterolateral craniofacial resection with orbital exenteration. Journal of Neurological Surgery Part B, 2019. In Press.
    72. Amare AT, Schubert KO, Hou L, Clark SR, Papiol S, Heilbronner U, Degenhardt F, Tekola-Ayele F, Hsu YH, Shekhtman T, Adli M, Akula N, Akiyama K, Ardau R, Arias B, Aubry JM, Backlund L, Bhattacharjee AK, Bellivier F, Benabarre A, Bengesser S, Biernacka JM, Birner A, Brichant-Petitjean C, Cervantes P, Chen HC, Chillotti C, Cichon S, Cruceanu C, Czerski PM, Dalkner N, Dayer A, Del Zompo M, DePaulo JR, Etain B, Falkai P, Forstner AJ, Frisen L, Frye MA, Fullerton JM, Gard S, Garnham JS, Goes FS, Grigoroiu-Serbanescu M, Grof P, Hashimoto R, Hauser J, Herms S, Hoffmann P, Hofmann A, Jamain S, Jimenez E, Kahn JP, Kassem L, Kuo PH, Kato T, Kelsoe J, Kittel-Schneider S, Kliwicki S, Konig B, Kusumi I, Laje G, Landen M, Lavebratt C, Leboyer M, Leckband SG, Tortorella A, Manchia M, Martinsson L, McCarthy MJ, McElroy S, Colom F, Mitjans M, Mondimore FM, Monteleone P, Nievergelt CM, Nothen MM, Novak T, O'Donovan C, Ozaki N, Osby U, Pfennig A, Potash JB, Reif A, Reininghaus E, Rouleau GA, Rybakowski JK, Schalling M, Schofield PR, Schweizer BW, Severino G, Shilling PD, Shimoda K, Simhandl C, Slaney CM, Squassina A, Stamm T, Stopkova P, Maj M, Turecki G, Vieta E, Volkert J, Witt S, Wright A, Zandi PP, Mitchell PB, Bauer M, Alda M, Rietschel M, McMahon FJ, Schulze TG, Baune BT. Association of polygenic score for schizophrenia and hla antigen and inflammation genes with response to lithium in bipolar affective disorder: A genome-wide association study. JAMA psychiatry. 2018;75(1):65-74.
    73. Arioka Y, Kushima I, Kubo H, Mori D, Ozaki N. Induced pluripotent stem cells derived from a schizophrenia patient with astn2 deletion. Stem cell research. 2018;30:81-4.
    74. Arioka Y, Kushima I, Mori D, Ozaki N. Three lines of induced pluripotent stem cells derived from a 15q11.2-q13.1 duplication syndrome patient. Stem cell research. 2018;31:240-3.
    75. Arioka Y, Shishido E, Kubo H, Kushima I, Yoshimi A, Kimura H, Ishizuka K, Aleksic B, Maeda T, Ishikawa M, Kuzumaki N, Okano H, Mori D, Ozaki N. Single-cell trajectory analysis of human homogenous neurons carrying a rare reln variant. Translational psychiatry. 2018;8(1):129.
    76. Bagarinao E, Watanabe H, Maesawa S, Mori D, Hara K, Kawabata K, Yoneyama N, Ohdake R, Imai K, Masuda M, Yokoi T, Ogura A, Wakabayashi T, Kuzuya M, Ozaki N, Hoshiyama M, Isoda H, Naganawa S, Sobue G. An unbiased data-driven age-related structural brain parcellation for the identification of intrinsic brain volume changes over the adult lifespan. NeuroImage. 2018;169:134-44.
    77. Fujishiro H, Okuda M, Iwamoto K, Miyata S, Torii Y, Iritani S, Ozaki N. Early diagnosis of lewy body disease in patients with late-onset psychiatric disorders using clinical history of rapid eye movement sleep behavior disorder and [(123) i]-metaiodobenzylguanidine cardiac scintigraphy. Psychiatry and clinical neurosciences. 2018;72(6):423-34.
    78. Hasegawa S, Miyake Y, Yoshimi A, Mouri A, Hida H, Yamada K, Ozaki N, Nabeshima T, Noda Y. Dysfunction of serotonergic and dopaminergic neuronal systems in the antidepressant-resistant impairment of social behaviors induced by social defeat stress exposure as juveniles. The international journal of neuropsychopharmacology. 2018;21(9):837-46.
    79. Ikeda M, Takahashi A, Kamatani Y, Momozawa Y, Saito T, Kondo K, Shimasaki A, Kawase K, Sakusabe T, Iwayama Y, Toyota T, Wakuda T, Kikuchi M, Kanahara N, Yamamori H, Yasuda Y, Watanabe Y, Hoya S, Aleksic B, Kushima I, Arai H, Takaki M, Hattori K, Kunugi H, Okahisa Y, Ohnuma T, Ozaki N, Someya T, Hashimoto R, Yoshikawa T, Kubo M, Iwata N. Genome-wide association study detected novel susceptibility genes for schizophrenia and shared trans-populations/diseases genetic effect. Schizophrenia bulletin. 2018.
    80. Ikeda M, Tanaka S, Saito T, Ozaki N, Kamatani Y, Iwata N. Re-evaluating classical body type theories: Genetic correlation between psychiatric disorders and body mass index. Psychological medicine. 2018;48(10):1745-8.
    81. Iritani S, Habuchi C, Sekiguchi H, Torii Y. Brain research and clinical psychiatry: Establishment of a psychiatry brain bank in japan. Nagoya journal of medical science. 2018;80(3):309-15.
    82. Iritani S, Torii Y, Habuchi C, Sekiguchi H, Fujishiro H, Yoshida M, Go Y, Iriki A, Isoda M, Ozaki N. The neuropathological investigation of the brain in a monkey model of autism spectrum disorder with abca13 deletion. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 2018;71:130-9.
    83. Ishizuka K, Kimura H, Kushima I, Inada T, Okahisa Y, Ikeda M, Iwata N, Mori D, Aleksic B, Ozaki N. Assessment of a glyoxalase i frameshift variant, p.P122fs, in japanese patients with schizophrenia. Psychiatric genetics. 2018;28(5):90-3.
    84. Ishizuka K, Tabata H, Ito H, Kushima I, Noda M, Yoshimi A, Usami M, Watanabe K, Morikawa M, Uno Y, Okada T, Mori D, Aleksic B, Ozaki N, Nagata KI. Possible involvement of a cell adhesion molecule, migfilin, in brain development and pathogenesis of autism spectrum disorders. Journal of neuroscience research. 2018;96(5):789-802.
    85. Iwata M, Iwamoto K, Kawano N, Kawaue T, Ozaki N. Evaluation method regarding the effect of psychotropic drugs on driving performance: A literature review. Psychiatry and clinical neurosciences. 2018;72(10):747-73.
    86. Kato K, Iwamoto K, Kawano N, Noda Y, Ozaki N, Noda A. Differential effects of physical activity and sleep duration on cognitive function in young adults. Journal of sport and health science. 2018;7(2):227-36.
    87. Kimura H, Kushima I, Yohimi A, Aleksic B, Ozaki N. Copy number variant in the region of adenosine kinase (adk) and its possible contribution to schizophrenia susceptibility. The international journal of neuropsychopharmacology. 2018;21(5):405-9.
    88. Kubota C, Inada T, Nakamura Y, Shiino T, Ando M, Aleksic B, Yamauchi A, Morikawa M, Okada T, Ohara M, Sato M, Murase S, Goto S, Kanai A, Ozaki N. Stable factor structure of the edinburgh postnatal depression scale during the whole peripartum period: Results from a japanese prospective cohort study. Scientific reports. 2018;8(1):17659.
    89. Kubota C, Okada T, Morikawa M, Nakamura Y, Yamauchi A, Ando M, Shiino T, Ohara M, Murase S, Goto S, Kanai A, Masuda T, Aleksic B, Ozaki N. Postpartum depression among women in nagoya indirectly exposed to the great east japan earthquake. Scientific reports. 2018;8(1):11624.
    90. Kunisawa K, Shimizu T, Kushima I, Aleksic B, Mori D, Osanai Y, Kobayashi K, Taylor AM, Bhat MA, Hayashi A, Baba H, Ozaki N, Ikenaka K. Dysregulation of schizophrenia-related aquaporin 3 through disruption of paranode influences neuronal viability. Journal of neurochemistry. 2018;147(3):395-408.
    91. Kushima I, Aleksic B, Nakatochi M, Shimamura T, Okada T, Uno Y, Morikawa M, Ishizuka K, Shiino T, Kimura H, Arioka Y, Yoshimi A, Takasaki Y, Yu Y, Nakamura Y, Yamamoto M, Iidaka T, Iritani S, Inada T, Ogawa N, Shishido E, Torii Y, Kawano N, Omura Y, Yoshikawa T, Uchiyama T, Yamamoto T, Ikeda M, Hashimoto R, Yamamori H, Yasuda Y, Someya T, Watanabe Y, Egawa J, Nunokawa A, Itokawa M, Arai M, Miyashita M, Kobori A, Suzuki M, Takahashi T, Usami M, Kodaira M, Watanabe K, Sasaki T, Kuwabara H, Tochigi M, Nishimura F, Yamasue H, Eriguchi Y, Benner S, Kojima M, Yassin W, Munesue T, Yokoyama S, Kimura R, Funabiki Y, Kosaka H, Ishitobi M, Ohmori T, Numata S, Yoshikawa T, Toyota T, Yamakawa K, Suzuki T, Inoue Y, Nakaoka K, Goto YI, Inagaki M, Hashimoto N, Kusumi I, Son S, Murai T, Ikegame T, Okada N, Kasai K, Kunimoto S, Mori D, Iwata N, Ozaki N. Comparative analyses of copy-number variation in autism spectrum disorder and schizophrenia reveal etiological overlap and biological insights. Cell reports. 2018;24(11):2838-56.
    92. Marui T, Torii Y, Iritani S, Sekiguchi H, Habuchi C, Fujishiro H, Oshima K, Niizato K, Hayashida S, Masaki K, Kira J, Ozaki N. The neuropathological study of myelin oligodendrocyte glycoprotein in the temporal lobe of schizophrenia patients. Acta neuropsychiatrica. 2018;30(4):232-40.
    93. Miyata A, Iwamoto K, Kawano N, Aleksic B, Ando M, Ebe K, Fujita K, Yokoyama M, Akiyama T, Igarashi Y, Ozaki N. Driving performance of stable outpatients with depression undergoing real-world treatment. Psychiatry and clinical neurosciences. 2018;72(6):399-408.
    94. Morita K, Miura K, Fujimoto M, Shishido E, Shiino T, Takahashi J, Yamamori H, Yasuda Y, Kudo N, Hirano Y, Koshiyama D, Okada N, Ikeda M, Onitsuka T, Ozaki N, Kasai K, Hashimoto R. Abnormalities of eye movement are associated with work hours in schizophrenia. Schizophrenia research. 2018;202:420-2.
    95. Mouri A, Ukai M, Uchida M, Hasegawa S, Taniguchi M, Ito T, Hida H, Yoshimi A, Yamada K, Kunimoto S, Ozaki N, Nabeshima T, Noda Y. Juvenile social defeat stress exposure persistently impairs social behaviors and neurogenesis. Neuropharmacology. 2018;133:23-37.
    96. Nakagawa T, Hiraga SI, Mizumura K, Hori K, Ozaki N, Koeda T. Topical thermal therapy with hot packs suppresses physical inactivity-induced mechanical hyperalgesia and up-regulation of ngf. The journal of physiological sciences : JPS. 2018;68(5):629-37.
    97. Ogasawara K, Nakamura Y, Kimura H, Aleksic B, Ozaki N. Issues on the diagnosis and etiopathogenesis of mood disorders: Reconsidering dsm-5. Journal of neural transmission (Vienna, Austria : 1996). 2018;125(2):211-22.
    98. Ohara M, Nakatochi M, Okada T, Aleksic B, Nakamura Y, Shiino T, Yamauchi A, Kubota C, Morikawa M, Murase S, Goto S, Kanai A, Kato R, Ando M, Ozaki N. Impact of perceived rearing and social support on bonding failure and depression among mothers: A longitudinal study of pregnant women. Journal of psychiatric research. 2018;105:71-7.
    99. Ozaki N. Right treatment for the right schizophrenic patients based on carbonyl stress pathophysiology. Psychiatry and clinical neurosciences. 2018;72(1):2.
    100. Reinbold CS, Forstner AJ, Hecker J, Fullerton JM, Hoffmann P, Hou L, Heilbronner U, Degenhardt F, Adli M, Akiyama K, Akula N, Ardau R, Arias B, Backlund L, Benabarre A, Bengesser S, Bhattacharjee AK, Biernacka JM, Birner A, Marie-Claire C, Cervantes P, Chen GB, Chen HC, Chillotti C, Clark SR, Colom F, Cousins DA, Cruceanu C, Czerski PM, Dayer A, Etain B, Falkai P, Frisen L, Gard S, Garnham JS, Goes FS, Grof P, Gruber O, Hashimoto R, Hauser J, Herms S, Jamain S, Jimenez E, Kahn JP, Kassem L, Kittel-Schneider S, Kliwicki S, Konig B, Kusumi I, Lackner N, Laje G, Landen M, Lavebratt C, Leboyer M, Leckband SG, Lopez Jaramillo CA, MacQueen G, Manchia M, Martinsson L, Mattheisen M, McCarthy MJ, McElroy SL, Mitjans M, Mondimore FM, Monteleone P, Nievergelt CM, Osby U, Ozaki N, Perlis RH, Pfennig A, Reich-Erkelenz D, Rouleau GA, Schofield PR, Schubert KO, Schweizer BW, Seemuller F, Severino G, Shekhtman T, Shilling PD, Shimoda K, Simhandl C, Slaney CM, Smoller JW, Squassina A, Stamm TJ, Stopkova P, Tighe SK, Tortorella A, Turecki G, Volkert J, Witt SH, Wright AJ, Young LT, Zandi PP, Potash JB, DePaulo JR, Bauer M, Reininghaus E, Novak T, Aubry JM, Maj M, Baune BT, Mitchell PB, Vieta E, Frye MA, Rybakowski JK, Kuo PH, Kato T, Grigoroiu-Serbanescu M, Reif A, Del Zompo M, Bellivier F, Schalling M, Wray NR, Kelsoe JR, Alda M, McMahon FJ, Schulze TG, Rietschel M, Nothen MM, Cichon S. Analysis of the influence of micrornas in lithium response in bipolar disorder. Frontiers in psychiatry. 2018;9:207.
    101. Sobue A, Kushima I, Nagai T, Shan W, Kohno T, Aleksic B, Aoyama Y, Mori D, Arioka Y, Kawano N, Yamamoto M, Hattori M, Nabeshima T, Yamada K, Ozaki N. Genetic and animal model analyses reveal the pathogenic role of a novel deletion of reln in schizophrenia. Scientific reports. 2018;8(1):13046.
    102. Takata A, Miyake N, Tsurusaki Y, Fukai R, Miyatake S, Koshimizu E, Kushima I, Okada T, Morikawa M, Uno Y, Ishizuka K, Nakamura K, Tsujii M, Yoshikawa T, Toyota T, Okamoto N, Hiraki Y, Hashimoto R, Yasuda Y, Saitoh S, Ohashi K, Sakai Y, Ohga S, Hara T, Kato M, Nakamura K, Ito A, Seiwa C, Shirahata E, Osaka H, Matsumoto A, Takeshita S, Tohyama J, Saikusa T, Matsuishi T, Nakamura T, Tsuboi T, Kato T, Suzuki T, Saitsu H, Nakashima M, Mizuguchi T, Tanaka F, Mori N, Ozaki N, Matsumoto N. Integrative analyses of de novo mutations provide deeper biological insights into autism spectrum disorder. Cell reports. 2018;22(3):734-47.
    103. Tsuruta Y, Iwamoto K, Banno M, Kawano N, Kohmura K, Miyata S, Fujishiro H, Noda Y, Noda A, Iritani S, Ozaki N. Effects of hypnotics on prefrontal cortex activity during a verbal fluency task in healthy male subjects: A near-infrared spectroscopy study. Human psychopharmacology. 2018;33(6):e2678.
    104. Yamamoto M, Kushima I, Suzuki R, Branko A, Kawano N, Inada T, Iidaka T, Ozaki N. Aberrant functional connectivity between the thalamus and visual cortex is related to attentional impairment in schizophrenia. Psychiatry research Neuroimaging. 2018;278:35-41.
    105. Yamasue H, Okada T, Munesue T, Kuroda M, Fujioka T, Uno Y, Matsumoto K, Kuwabara H, Mori D, Okamoto Y, Yoshimura Y, Kawakubo Y, Arioka Y, Kojima M, Yuhi T, Owada K, Yassin W, Kushima I, Benner S, Ogawa N, Eriguchi Y, Kawano N, Uemura Y, Yamamoto M, Kano Y, Kasai K, Higashida H, Ozaki N, Kosaka H. Effect of intranasal oxytocin on the core social symptoms of autism spectrum disorder: A randomized clinical trial. Molecular psychiatry. 2018.
    106. Yamauchi A, Okada T, Ando M, Morikawa M, Nakamura Y, Kubota C, Ohara M, Murase S, Goto S, Kanai A, Ozaki N. Validation and factor analysis of the japanese version of the highs scale in perinatal women. Frontiers in psychiatry. 2018;9:269.
    107. Yu Y, Lin Y, Takasaki Y, Wang C, Kimura H, Xing J, Ishizuka K, Toyama M, Kushima I, Mori D, Arioka Y, Uno Y, Shiino T, Nakamura Y, Okada T, Morikawa M, Ikeda M, Iwata N, Okahisa Y, Takaki M, Sakamoto S, Someya T, Egawa J, Usami M, Kodaira M, Yoshimi A, Oya-Ito T, Aleksic B, Ohno K, Ozaki N. Rare loss of function mutations in n-methyl-d-aspartate glutamate receptors and their contributions to schizophrenia susceptibility. Translational psychiatry. 2018;8(1):12.
    108. Yukawa T, Iwakura Y, Takei N, Saito M, Watanabe Y, Toyooka K, Igarashi M, Niizato K, Oshima K, Kunii Y, Yabe H, Matsumoto J, Wada A, Hino M, Iritani S, Niwa SI, Takeuchi R, Takahashi H, Kakita A, Someya T, Nawa H. Pathological alterations of chondroitin sulfate moiety in postmortem hippocampus of patients with schizophrenia. Psychiatry research. 2018;270:940-6.
    109. Aleksic B, Ozaki N. Schizophrenia polygenic risk score and prepubertal developmental impairments. Lancet Psychiatry. 2017;4(1):7-8.
    110. Iwamoto K, Fujishiro H, Ozaki N. Effect of aripiprazole augmentation for depressive symptoms changes with progression of lewy body disease. Psychiatry Clin Neurosci. 2017;71(1):74-75.
    111. Kato K, Miyata S, Ando M, Matsuoka H, Yasuma F, Iwamoto K, Kawano N, Banno M, Ozaki N, Noda A. Influence of sleep duration on cortical oxygenation in elderly individuals. Psychiatry Clin Neurosci. 2017;71(1):44-51.
    112. Munechika T, Fujishiro H, Okuda M, Iwamoto K, Torii Y, Iritani S, Ozaki N. Rapid eye movement sleep without atonia may help diagnose lewy body disease in middle-aged and older patients with somatic symptom disorder. Psychogeriatrics. 2017;17(1):61-69.
    113. Ohara M, Okada T, Aleksic B, Morikawa M, Kubota C, Nakamura Y, Shiino T, Yamauchi A, Uno Y, Murase S, Goto S, Kanai A, Masuda T, Nakatochi M, Ando M, Ozaki N. Social support helps protect against perinatal bonding failure and depression among mothers: A prospective cohort study. Sci Rep. 2017;7(1):9546.
    114. Saito T, Ikeda M, Hashimoto R, Iwata N, Yamamori H, Yasuda Y, Fujimoto M, Kondo K, Shimasaki A, Kawase K, Miyata M, Mushiroda T, Ozeki T, Kubo M, Fujita K, Kida N, Nakai M, Otsuru T, Fukuji Y, Murakami M, Mizuno K, Shiratsuchi T, Numata S, Ohmori T, Ueno S I, Yada Y, Tanaka S, Kishi Y, Takaki M, Mamoto A, Taniguchi N, Sawa Y, Watanabe H, Noda T, Amano Y, Kimura T, Fukao T, Suwa T, Murai T, Kubota M, Ueda K, Tabuse H, Kanahara N, Kawai N, Nemoto K, Makinodan M, Nishihata Y, Hashimoto N, Kusumi I, Fujii Y, Miyata R, Hirakawa K, Ozaki N. Transethnic replication study to assess the association between clozapine-induced agranulocytosis/granulocytopenia and genes at 12p12.2 in a Japanese population. Biol Psychiatry. 2017;82(1):e9-e10.
    115. Sekiguchi H, Moriwaki M, Iritani S, Habuchi C, Torii Y, Umeda K, Fujishiro H, Yoshida M, Fujita K. An autopsy case of dementia with Lewy bodies clinically diagnosed to have a behavioral variant of frontotemporal dementia. Clin Neuropathol. 2017;36 (2017)(1):23-30.
    116. Fujioi J, Iwamoto K, Banno M, Kikuchi T, Aleksic B, Ozaki N. Effect of adjunctive aripiprazole on sexual dysfunction in schizophrenia: A preliminary open-label study. Pharmacopsychiatry. 2017;50(2):74-78.
    117. Ukai K, Fujishiro H, Ozaki N. Effectiveness of low-dose pregabalin in three patients with lewy body disease and central neuropathic pain. Psychogeriatrics. 2017;17(2):115-119.
    118. Ukai K, Fujishiro H, Watanabe M, Kosaka K, Ozaki N. Similarity of symptoms between transient epileptic amnesia and lewy body disease. Psychogeriatrics. 2017;17(2):120-125.
    119. Ogasawara K, Nakamura Y, Kimura H, Aleksic B, Ozaki N. Issues on the diagnosis and etiopathogenesis of mood disorders: reconsidering DSM-5. J Neural Transm. 2017;125(2):211-222.
    120. Kushima I, Aleksic B, Nakatochi M, Shimamura T, Shiino T, Yoshimi A, Kimura H, Takasaki Y, Wang C, Xing J, Ishizuka K, Oya-Ito T, Nakamura Y, Arioka Y, Maeda T, Yamamoto M, Yoshida M, Noma H, Hamada S, Morikawa M, Uno Y, Okada T, Iidaka T, Iritani S, Yamamoto T, Miyashita M, Kobori A, Arai M, Itokawa M, Cheng M C, Chuang Y A, Chen C H, Suzuki M, Takahashi T, Hashimoto R, Yamamori H, Yasuda Y, Watanabe Y, Nunokawa A, Someya T, Ikeda M, Toyota T, Yoshikawa T, Numata S, Ohmori T, Kunimoto S, Mori D, Iwata N, Ozaki N. High-resolution copy number variation analysis of schizophrenia in Japan. Mol Psychiatry. 2017;22(3):430-440.
    121. Fujishiro H, Okuda M, Iwamoto K, Miyata S, Otake H, Noda A, Iritani S, Ozaki N. Rem sleep without atonia in middle-aged and older psychiatric patients and lewy body disease: A case series. Int J Geriatr Psychiatry. 2017;32(4):397-406.
    122. Kobayashi Y, Nagashima W, Tokura T, Yoshida K, Umemura E, Miyauchi T, Arao M, Ito M, Kimura H, Kurita K, Ozaki N. Duloxetine plasma concentrations and its effectiveness in the treatment of nonorganic chronic pain in the orofacial region. Clin Neuropharmacol. 2017;40(4):163-168.
    123. Fujino H, Sumiyoshi C, Yasuda Y, Yamamori H, Fujimoto M, Fukunaga M, Miura K, Takebayashi Y, Okada N, Isomura S, Kawano N, Toyomaki A, Kuga H, Isobe M, Oya K, Okahisa Y, Takaki M, Hashimoto N, Kato M, Onitsuka T, Ueno T, Ohnuma T, Kasai K, Ozaki N, Sumiyoshi T, Imura O, Hashimoto R, Cocoro. Estimated cognitive decline in patients with schizophrenia: A multicenter study. Psychiatry Clin Neurosci. 2017;71(5):294-300.
    124. Sekiguchi H, Iritani S, Fujita K. Bright light therapy for sleep disturbance in dementia is most effective for mild to moderate Alzheimer's type dementia: a case series. Psychogeriatrics. 2017;17(5):275-281.
    125. Onishi Y, Kimura H, Hori T, Kishi S, Kamei H, Kurata N, Tsuboi C, Yamaguchi N, Takahashi M, Sunada S, Hirano M, Fujishiro H, Okada T, Ishigami M, Goto H, Ozaki N, Ogura Y. Risk of alcohol use relapse after liver transplantation for alcoholic liver disease. World J Gastroenterol. 2017;23(5):869-875.
    126. Goto A, Yoshimi A, Nagai T, Ukigai M, Mouri A, Ozaki N, Noda Y. Human neutrophils show decreased survival upon long-term exposure to clozapine. Hum Psychopharmacol Clin Exp. 2017;32(6):e2629.
    127. Sumiyoshi T, Toyomaki A, Kawano N, Kitajima T, Kusumi I, Ozaki N, Iwata N, Nakagome K. Reliability and validity of the california verbal learning test-ii - Japanese version. Psychiatry Clin Neurosci. 2017;71(6):417-418.
    128. Sumiyoshi T, Toyomaki A, Kawano N, Kitajima T, Kusumi I, Ozaki N, Iwata N, Sueyoshi K, Nakagome K. Verbal memory impairments in bipolar disorder: Effect of type of word learning tasks. Psychiatry Clin Neurosci. 2017;71(8):570-571.
    129. Ishizuka K, Fujita Y, Kawabata T, Kimura H, Iwayama Y, Inada T, Okahisa Y, Egawa J, Usami M, Kushima I, Uno Y, Okada T, Ikeda M, Aleksic B, Mori D, Someya T, Yoshikawa T, Iwata N, Nakamura H, Yamashita T, Ozaki N. Rare genetic variants in cx3cr1 and their contribution to the increased risk of schizophrenia and autism spectrum disorders. Transl Psychiatry. 2017;7(8):e1184.
    130. Kasahara T, Ishiwata M, Kakiuchi C, Fuke S, Iwata N, Ozaki N, Kunugi H, Minabe Y, Nakamura K, Iwata Y, Fujii K, Kanba S, Ujike H, Kusumi I, Kataoka M, Matoba N, Takata A, Iwamoto K, Yoshikawa T, Kato T. Enrichment of deleterious variants of mitochondrial DNA polymerase gene (polg1) in bipolar disorder. Psychiatry Clin Neurosci. 2017;71(8):518-529.
    131. Kimura H, Fujita Y, Kawabata T, Ishizuka K, Wang C, Iwayama Y, Okahisa Y, Kushima I, Morikawa M, Uno Y, Okada T, Ikeda M, Inada T, Branko A, Mori D, Yoshikawa T, Iwata N, Nakamura H, Yamashita T, Ozaki N. A novel rare variant r292h in rtn4r affects growth cone formation and possibly contributes to schizophrenia susceptibility. Transl Psychiatry. 2017;7(8):e1214.
    132. Hill R S, Goldberg A P, Poultney C, Minshew N J, Kushima I, Aleksic B, Ozaki N, Parellada M, Arango C, Penzol M J, Carracedo A, Kolevzon A, Hultman C M, Weiss L A, Fromer M, Chiocchetti A G, Freitag C M, Church G M, Scherer S W, Buxbaum J D, Walsh C A. Rates, distribution and implications of postzygotic mosaic mutations in autism spectrum disorder. Nat Neurosci. 2017;20(9):1217-1224.
    133. Ohara M, Okada T, Kubota C, Nakamura Y, Shiino T, Aleksic B, Morikawa M, Yamauchi A, Uno Y, Murase S, Goto S, Kanai A, Masuda T, Ando M, Ozaki N. Relationship between maternal depression and bonding failure: A prospective cohort study of pregnant women. Psychiatry Clin Neurosci. 2017;71(10):733-741.
    134. Matsumoto Y, Niwa M, Mouri A, Noda Y, Fukushima T, Ozaki N, Nabeshima T. Adolescent stress leads to glutamatergic disturbance through dopaminergic abnormalities in the prefrontal cortex of genetically vulnerable mice. Psychopharmacology. 2017;234(20):3055-3074.
    135. Kimura H, Kushima I, Yohimi A, Aleksic B, Ozaki N. Copy number variant in the region of adenosine kinase (adk) and its possible contribution to schizophrenia susceptibility. Int J Neuropsychopharmacol. 2017　 pyx103, https://doi.org/10.1093/ijnp/pyx103.
    136. Kimura H, Onishi Y, Kishi S, Kurata N, Ogiso S, Kamei H, Tsuboi C, Yamaguchi N, Shiga A, Kondo M, Yokoyama Y, Takasato F, Fujishiro H, Ishizuka K, Okada T, Ogura Y, Ozaki N. Successful post-transplant psychiatric interventions during long-term follow-up of patients receiving liver transplants for alcoholic liver disease. Am J Case Rep. 2017;18:1215-1219.
    137. Kohmura K, Adachi Y, Tanaka S, Katayama H, Imaeda M, Kawano N, Nishioka K, Ando M, Iidaka T, Ozaki N. Regional decrease in gray matter volume is related to body dissatisfaction in anorexia nervosa. Psychiatry Res Neuroimaging. 2017;267:51-58.
    138. Morosawa S, Iritani S, Fujishiro H, Sekiguchi H, Torii Y, Habuchi C, Kuroda K, Kaibuchi K, Ozaki N. Neuropeptide y neuronal network dysfunction in the frontal lobe of a genetic mouse model of schizophrenia. Neuropeptides. 2017;62:27-35.
    139. Sumiyoshi T, Toyomaki A, Kawano N, Kitajima T, Kusumi I, Ozaki N, Iwata N, Sueyoshi K, Nakagome K. Verbal memory impairment in patients with subsyndromal bipolar disorder. Front Psychiatry. 2017;8:168.
    140. Umeda K, Iritani S, Fujishiro H, Sekiguchi H, Torii Y, Habuchi C, Kuroda K, Kaibuchi K, Ozaki N. Immunohistochemical Evaluation of the GABAergic Neuronal System in the Prefrontal Cortex of a DISC1 Knockout Mouse Model of Schizophrenia. Synapse, in press.
    141. Ukai K, Fujishiro H, Watanabe M, Kosaka K, Ozaki N. Similarity of symptoms between transient epileptic amnesia and Lewy body disease. Psychogeriatrics, in press.
    142. Ukai K, Fujishiro H, Ozaki N. Effectiveness of low-dose pregabalin in three patients with Lewy body disease and central neuropathic pain. Psychogeriatrics, in press.
    143. Ukai K, Fujishiro H, Iritani S, Ozaki N. Long-term efficacy of donepezil for relapse of visual hallucinations in patients with dementia with Lewy bodies. Psychogeriatrics, in press.
    144. Torii Y, Iritani S, Fujishiro H, Sekiguchi H, Habuchi C, Umeda K, Matsunaga S, Mimuro M, Ozaki N, Yoshida M, Fujita K. An autopsy case of cortical superficial siderosis with persistent abnormal behavior. Neuropathology, in press.
    145. Sekiguchi H, Moriwaki M, Iritani S, Habuchi C, Torii Y, Umeda K, Fujishiro H, Yoshida M, Fujita K. An autopsy case of dementia with Lewy bodies clinically diagnosed to have a behavioral variant of frontotemporal dementia. Clin Neuropathol, in press.
    146. Okada N, Fukunaga M, Yamashita F, Koshiyama D, Yamamori H, Ohi K, Yasuda Y, Fujimoto M, Watanabe Y, Yahata N, Nemoto K, Hibar DP, van Erp TG, Fujino H, Isobe M, Isomura S, Natsubori T, Narita H, Hashimoto N, Miyata J, Koike S, Takahashi T, Yamasue H, Matsuo K, Onitsuka T, Iidaka T, Kawasaki Y, Yoshimura R, Watanabe Y, Suzuki M, Turner JA, Takeda M, Thompson PM, Ozaki N, Kasai K, Hashimoto R. Abnormal asymmetries in subcortical brain volume in schizophrenia. Mol Psychiatry, in press.
    147. Munechika T, Fujishiro H, Okuda M, Iwamoto K, Torii Y, Iritani S, Ozaki N. Rapid eye movement sleep without atonia may help diagnose Lewy body disease in middle-aged and older patients with somatic symptom disorder. Psychogeriatrics, in press.
    148. Miyashita M, Watanabe T, Ichikawa T, Toriumi K, Horiuchi Y, Kobori A, Kushima I, Hashimoto R, Fukumoto M, Koike S, Ujike H, Arinami T, Tatebayashi Y, Kasai K, Takeda M, Ozaki N, Okazaki Y, Yoshikawa T, Amano N, Washizuka S, Yamamoto H, Miyata T, Itokawa M, Yamamoto Y, Arai M. The regulation of soluble receptor for AGEs contributes to carbonyl stress in schizophrenia. Biochem Biophys Res Commun, in press.
    149. Kushima I, Aleksic B, Nakatochi M, Shimamura T, Shiino T, Yoshimi A, Kimura H, Takasaki Y, Wang C, Xing J, Ishizuka K, Oya-Ito T, Nakamura Y, Arioka Y, Maeda T, Yamamoto M, Yoshida M, Noma H, Hamada S, Morikawa M, Uno Y, Okada T, Iidaka T, Iritani S, Yamamoto T, Miyashita M, Kobori A, Arai M, Itokawa M, Cheng MC, Chuang YA, Chen CH, Suzuki M, Takahashi T, Hashimoto R, Yamamori H, Yasuda Y, Watanabe Y, Nunokawa A, Someya T, Ikeda M, Toyota T, Yoshikawa T, Numata S, Ohmori T, Kunimoto S, Mori D, Iwata N, Ozaki N. High-resolution copy number variation analysis of schizophrenia in Japan. Mol Psychiatry, in press.
    150. Kuroki T, Ishitobi M, Kamio Y, Sugihara G, Murai T, Motomura K, Ogasawara K, Kimura H, Aleksic B, Ozaki N, Nakao T, Yamada K, Yoshiuchi K, Kiriike N, Ishikawa T, Kubo C, Matsunaga C, Miyata H, Asada T, Kanba S. Current Viewpoints on DSM-5 in Japan. Psychiatry Clin Neurosci, in press.
    151. Kimura H, Wang C, Ishizuka K, Xing J, Takasaki Y, Kushima I, Aleksic B, Uno Y, Okada T, Ikeda M, Mori D, Inada T, Iwata N, Ozaki N. Identification of a rare variant in CHD8 that contributes to schizophrenia and autism spectrum disorder susceptibility. Schizophr Res, in press.
    152. Kato K, Miyata S, Ando M, Matsuoka H, Yasuma F, Iwamoto K, Kawano N, Banno M, Ozaki N, Noda A. Influence of sleep duration on cortical oxygenation in elderly individuals. Psychiatry Clin Neurosci, in press.
    153. Fujishiro H, Okuda M, Iwamoto K, Miyata S, Otake H, Noda A, Iritani S, Ozaki N. REM sleep without atonia in middle-aged and older psychiatric patients and Lewy body disease: a case series. Int J Geriatr Psychiatry, in press.
    154. Fujioi J, Iwamoto K, Banno M, Kikuchi T, Aleksic B, Ozaki N. Effect of Adjunctive Aripiprazole on Sexual Dysfunction in Schizophrenia: A Preliminary Open-Label Study. Pharmacopsychiatry, in press.
    155. Yoshida K, Go Y, Kushima I, Toyoda A, Fujiyama A, Imai H, Saito N, Iriki A, Ozaki N, Isoda M. Single-neuron and genetic correlates of autistic behavior in macaque. Sci Adv, 2016; 2: e1600558.
    156. Yano M, Kawano N, Tanaka S, Kohmura K, Katayama H, Nishioka K, Ozaki N. Dysfunction of response inhibition in eating disorders. J Clin Exp Neuropsychol, 2016; 38: 700-708.
    157. Xing J, Kimura H, Wang C, Ishizuka K, Kushima I, Arioka Y, Yoshimi A, Nakamura Y, Shiino T, Oya-Ito T, Takasaki Y, Uno Y, Okada T, Iidaka T, Aleksic B, Mori D, Ozaki N. Resequencing and Association Analysis of Six PSD-95-Related Genes as Possible Susceptibility Genes for Schizophrenia and Autism Spectrum Disorders. Sci Rep, 2016; 6: 27491.
    158. Tsujii N, Saito T, Izumoto Y, Usami M, Okada T, Negoro H, Iida J. Experiences with Patient Refusal of Off-Label Prescribing of Psychotropic Medications to Children and Adolescents in Japan. J Child Adolesc Psychopharmacol, 2016; 26: 642-645.
    159. Takasaki Y, Koide T, Wang C, Kimura H, Xing J, Kushima I, Ishizuka K, Mori D, Sekiguchi M, Ikeda M, Aizawa M, Tsurumaru N, Iwayama Y, Yoshimi A, Arioka Y, Yoshida M, Noma H, Oya-Ito T, Nakamura Y, Kunimoto S, Aleksic B, Uno Y, Okada T, Ujike H, Egawa J, Kuwabara H, Someya T, Yoshikawa T, Iwata N, Ozaki N. Mutation screening of GRIN2B in schizophrenia and autism spectrum disorder in a Japanese population. Sci Rep, 2016; 6: 33311.
    160. Sugimoto H, Kawashima H, Ohno E, Hayashi D, Kuwahara T, Morishima T, Kawai M, Suhara H, Takeyama T, Yamamura T, Funasaka K, Nakamura M, Miyahara R, Watanabe O, Ishigami M, Suzuki M, Kimura H, Ozaki N, Hashimoto S, Goto H, Hirooka Y. The prognostic factors and trajectory of HRQOL in patients with pancreatic cancer who received psychiatric intervention. J Gastroenterol Hepatol, 2016; 31: 685-690.
    161. Ohara M, Okada T, Kubota C, Nakamura Y, Shiino T, Aleksic B, Morikawa M, Yamauchi A, Uno Y, Murase S, Goto S, Kanai A, Masuda T, Ozaki N. Validation and factor analysis of mother-infant bonding questionnaire in pregnant and postpartum women in Japan. BMC Psychiatry, 2016; 16: 212.
    162. Nakazawa T, Hashimoto R, Sakoori K, Sugaya Y, Tanimura A, Hashimotodani Y, Ohi K, Yamamori H, Yasuda Y, Umeda-Yano S, Kiyama Y, Konno K, Inoue T, Yokoyama K, Inoue T, Numata S, Ohnuma T, Iwata N, Ozaki N, Hashimoto H, Watanabe M, Manabe T, Yamamoto T, Takeda M, Kano M. Corrigendum: Emerging roles of ARHGAP33 in intracellular trafficking of TrkB and pathophysiology of neuropsychiatric disorders. Nat Commun, 2016; 7: 11466.
    163. Nakazawa T, Hashimoto R, Sakoori K, Sugaya Y, Tanimura A, Hashimotodani Y, Ohi K, Yamamori H, Yasuda Y, Umeda-Yano S, Kiyama Y, Konno K, Inoue T, Yokoyama K, Inoue T, Numata S, Ohnuma T, Iwata N, Ozaki N, Hashimoto H, Watanabe M, Manabe T, Yamamoto T, Takeda M, Kano M. Emerging roles of ARHGAP33 in intracellular trafficking of TrkB and pathophysiology of neuropsychiatric disorders. Nat Commun, 2016; 7: 10594.
    164. Isles AR, Ingason A, Lowther C, Walters J, Gawlick M, Stober G, Rees E, Martin J, Little RB, Potter H, Georgieva L, Pizzo L, Ozaki N, Aleksic B, Kushima I, Ikeda M, Iwata N, Levinson DF, Gejman PV, Shi J, Sanders AR, Duan J, Willis J, Sisodiya S, Costain G, Werge TM, Degenhardt F, Giegling I, Rujescu D, Hreidarsson SJ, Saemundsen E, Ahn JW, Ogilvie C, Girirajan SD, Stefansson H, Stefansson K, O'Donovan MC, Owen MJ, Bassett A, Kirov G. Parental Origin of Interstitial Duplications at 15q11.2-q13.3 in Schizophrenia and Neurodevelopmental Disorders. PLoS Genet, 2016; 12: e1005993.
    165. Ishizuka K, Kimura H, Wang C, Xing J, Kushima I, Arioka Y, Oya-Ito T, Uno Y, Okada T, Mori D, Aleksic B, Ozaki N. Investigation of Rare Single-Nucleotide PCDH15 Variants in Schizophrenia and Autism Spectrum Disorders. PLoS One, 2016; 11: e0153224.
    166. Iritani S, Sekiguchi H, Habuchi C, Torii Y, Kuroda K, Kaibuchi K, Ozaki N. Catecholaminergic neuronal network dysfunction in the frontal lobe of a genetic mouse model of schizophrenia. Acta Neuropsychiatr, 2016; 28: 117-123.
    167. Hou L, Heilbronner U, Degenhardt F, Adli M, Akiyama K, Akula N, Ardau R, Arias B, Backlund L, Banzato CE, Benabarre A, Bengesser S, Bhattacharjee AK, Biernacka JM, Birner A, Brichant-Petitjean C, Bui ET, Cervantes P, Chen GB, Chen HC, Chillotti C, Cichon S, Clark SR, Colom F, Cousins DA, Cruceanu C, Czerski PM, Dantas CR, Dayer A, Etain B, Falkai P, Forstner AJ, Frisen L, Fullerton JM, Gard S, Garnham JS, Goes FS, Grof P, Gruber O, Hashimoto R, Hauser J, Herms S, Hoffmann P, Hofmann A, Jamain S, Jimenez E, Kahn JP, Kassem L, Kittel-Schneider S, Kliwicki S, Konig B, Kusumi I, Lackner N, Laje G, Landen M, Lavebratt C, Leboyer M, Leckband SG, Jaramillo CA, MacQueen G, Manchia M, Martinsson L, Mattheisen M, McCarthy MJ, McElroy SL, Mitjans M, Mondimore FM, Monteleone P, Nievergelt CM, Nothen MM, Osby U, Ozaki N, Perlis RH, Pfennig A, Reich-Erkelenz D, Rouleau GA, Schofield PR, Schubert KO, Schweizer BW, Seemuller F, Severino G, Shekhtman T, Shilling PD, Shimoda K, Simhandl C, Slaney CM, Smoller JW, Squassina A, Stamm T, Stopkova P, Tighe SK, Tortorella A, Turecki G, Volkert J, Witt S, Wright A, Young LT, Zandi PP, Potash JB, DePaulo JR, Bauer M, Reininghaus EZ, Novak T, Aubry JM, Maj M, Baune BT, Mitchell PB, Vieta E, Frye MA, Rybakowski JK, Kuo PH, Kato T, Grigoroiu-Serbanescu M, Reif A, Del Zompo M, Bellivier F, Schalling M, Wray NR, Kelsoe JR, Alda M, Rietschel M, McMahon FJ, Schulze TG. Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study. Lancet, 2016; 387: 1085-1093.
    168. Higashiyama R, Ohnuma T, Takebayashi Y, Hanzawa R, Shibata N, Yamamori H, Yasuda Y, Kushima I, Aleksic B, Kondo K, Ikeda M, Hashimoto R, Iwata N, Ozaki N, Arai H. Association of copy number polymorphisms at the promoter and translated region of COMT with Japanese patients with schizophrenia. Am J Med Genet B Neuropsychiatr Genet, 2016; 171: 447-457.
    169. Goto A, Mouri A, Nagai T, Yoshimi A, Ukigai M, Tsubai T, Hida H, Ozaki N, Noda Y. Involvement of the histamine H4 receptor in clozapine-induced hematopoietic toxicity: Vulnerability under granulocytic differentiation of HL-60 cells. Toxicol Appl Pharmacol, 2016; 306: 8-16.
    170. Fujishiro H, Iritani S, Sekiguchi H, Habuchi C, Torii Y, Matsunaga S, Ozaki N, Yoshida M, Fujita K. Hypochondriasis as an early manifestation of dementia with Lewy bodies: an autopsied case report. Psychogeriatrics, 2016; 16: 139-144.
    171. Yamamoto M, Kushima I, Kimura H, Hayashi A, Kawano N, Aleksic B, Iidaka T, Ozaki N. White matter microstructure between the pre-SMA and the cingulum bundle is related to response conflict in healthy subjects. Brain Behav, 2015; 5: e00375.
    172. Wang C, Aleksic B, Ozaki N. Glia-related genes and their contribution to schizophrenia. Psychiatry Clin Neurosci, 2015; 69: 448-461.
    173. Usami M, Iwadare Y, Watanabe K, Ushijima H, Kodaira M, Okada T, Sasayama D, Sugiyama N, Saito K. A case-control study of the difficulties in daily functioning experienced by children with depressive disorder. J Affect Disord, 2015; 179: 167-174.
    174. Uno Y, Uchiyama T, Kurosawa M, Aleksic B, Ozaki N. Early exposure to the combined measles-mumps-rubella vaccine and thimerosal-containing vaccines and risk of autism spectrum disorder. Vaccine, 2015; 33: 2511-2516.
    175. Uno K, Nishizawa D, Seo S, Takayama K, Matsumura S, Sakai N, Ohi K, Nabeshima T, Hashimoto R, Ozaki N, Hasegawa J, Sato N, Tanioka F, Sugimura H, Fukuda KI, Higuchi S, Ujike H, Inada T, Iwata N, Sora I, Iyo M, Kondo N, Won MJ, Naruse N, Uehara-Aoyama K, Itokawa M, Yamada M, Ikeda K, Miyamoto Y, Nitta A. The Piccolo Intronic Single Nucleotide Polymorphism rs13438494 Regulates Dopamine and Serotonin Uptake and Shows Associations with Dependence-Like Behavior in Genomic Association Study. Curr Mol Med, 2015; 15: 265-274.
    176. Tokura T, Kimura H, Ito M, Nagashima W, Sato N, Kimura Y, Arao M, Aleksic B, Yoshida K, Kurita K, Ozaki N. Temperament and character profiles of patients with burning mouth syndrome. J Psychosom Res, 2015; 78: 495-498.
    177. Tanaka S, Yoshida K, Katayama H, Kohmura K, Kawano N, Imaeda M, Kato S, Ando M, Aleksic B, Nishioka K, Ozaki N. Association of Beck Depression Inventory score and Temperament and Character Inventory-125 in patients with eating disorders and severe malnutrition. J Eat Disord, 2015; 3: 36.
    178. Takahashi T, Nakamura M, Nakamura Y, Aleksic B, Kido M, Sasabayashi D, Takayanagi Y, Furuichi A, Nishikawa Y, Noguchi K, Ozaki N, Suzuki M. The Disrupted-in-Schizophrenia-1 Ser704Cys polymorphism and brain neurodevelopmental markers in schizophrenia and healthy subjects. Prog Neuropsychopharmacol Biol Psychiatry, 2015; 56: 11-17.
    179. Ozaki N, Otsubo T, Kato M, Higuchi T, Ono H, Kamijima K, Group AS. Efficacy of aripiprazole augmentation in Japanese patients with major depressive disorder: A subgroup analysis and Montgomery-Asberg Depression Rating Scale and Hamilton Rating Scale for Depression item analyses of the Aripiprazole Depression Multicenter Efficacy study. Psychiatry Clin Neurosci, 2015; 69: 34-42.
    180. Okada T, Ozaki N. What is the nature of the autism 'spectrum'? Psychiatry Clin Neurosci, 2015; 69: 129-130.
    181. Okada T, Kubota Y, Sato W, Murai T, Pellion F, Gorog F. Common impairments of emotional facial expression recognition in schizophrenia across French and Japanese cultures. Front Psychol, 2015; 6: 1018.
    182. Noda A, Miyaji M, Wakuda Y, Hara Y, Yasuma F, Fukuda T, Iwamoto K, Ozaki N. Simultaneous Measurement of Heart Rate Variability and Blinking Duration to Predict Sleep Onset and Drowsiness in Drivers. J Sleep Disord Ther, 2015; 4: 213.
    183. Nishizawa D, Kasai S, Hasegawa J, Sato N, Yamada H, Tanioka F, Nagashima M, Katoh R, Satoh Y, Tagami M, Ujike H, Ozaki N, Inada T, Iwata N, Sora I, Iyo M, Yamada M, Kondo N, Won MJ, Naruse N, Uehara-Aoyama K, Itokawa M, Ohi K, Hashimoto R, Tanisawa K, Arai T, Mori S, Sawabe M, Naka-Mieno M, Yamada Y, Yamada M, Sato N, Muramatsu M, Tanaka M, Irukayama-Tomobe Y, Saito YC, Sakurai T, Hayashida M, Sugimura H, Ikeda K. Associations between the orexin (hypocretin) receptor 2 gene polymorphism Val308Ile and nicotine dependence in genome-wide and subsequent association studies. Mol Brain, 2015; 8: 50.
    184. Morikawa M, Okada T, Ando M, Aleksic B, Kunimoto S, Nakamura Y, Kubota C, Uno Y, Tamaji A, Hayakawa N, Furumura K, Shiino T, Morita T, Ishikawa N, Ohoka H, Usui H, Banno N, Murase S, Goto S, Kanai A, Masuda T, Ozaki N. Relationship between social support during pregnancy and postpartum depressive state: a prospective cohort study. Sci Rep, 2015; 5: 10520.
    185. Miyata S, Noda A, Iwamoto K, Kawano N, Banno M, Tsuruta Y, Noda Y, Ozaki N. Impaired cortical oxygenation is related to mood disturbance resulting from three nights of sleep restriction. Sleep and Biological Rhythms, 2015; 13: 387-394.
    186. Miyata A, Iwamoto K, Kawano N, Kohmura K, Yamamoto M, Aleksic B, Ebe K, Noda A, Noda Y, Iritani S, Ozaki N. The effects of acute treatment with ramelteon, triazolam, and placebo on driving performance, cognitive function, and equilibrium function in healthy volunteers. Psychopharmacology (Berl), 2015; 232: 2127-2137.
    187. Kimura H, Tsuboi D, Wang C, Kushima I, Koide T, Ikeda M, Iwayama Y, Toyota T, Yamamoto N, Kunimoto S, Nakamura Y, Yoshimi A, Banno M, Xing J, Takasaki Y, Yoshida M, Aleksic B, Uno Y, Okada T, Iidaka T, Inada T, Suzuki M, Ujike H, Kunugi H, Kato T, Yoshikawa T, Iwata N, Kaibuchi K, Ozaki N. Identification of Rare, Single-Nucleotide Mutations in NDE1 and Their Contributions to Schizophrenia Susceptibility. Schizophr Bull, 2015; 41: 744-753.
    188. Kimura H, Tanaka S, Kushima I, Koide T, Banno M, Kikuchi T, Nakamura Y, Shiino T, Yoshimi A, Oya-Ito T, Xing J, Wang C, Takasaki Y, Aleksic B, Okada T, Ikeda M, Inada T, Iidaka T, Iwata N, Ozaki N. Association study of BCL9 gene polymorphism rs583583 with schizophrenia and negative symptoms in Japanese population. Sci Rep, 2015; 5: 15705.
    189. Kimura H, Onishi Y, Sunada S, Kishi S, Suzuki N, Tsuboi C, Yamaguchi N, Imai H, Kamei H, Fujisiro H, Okada T, Ishigami M, Ogura Y, Kiuchi T, Ozaki N. Postoperative Psychiatric Complications in Living Liver Donors. Transplant Proc, 2015; 47: 1860-1865.
    190. Ito M, Tokura T, Yoshida K, Nagashima W, Kimura H, Umemura E, Tachibana M, Miyauchi T, Kobayashi Y, Arao M, Ozaki N, Kurita K. Five Patients With Burning Mouth Syndrome in Whom an Antidepressant (Serotonin-Noradrenaline Reuptake Inhibitor) Was Not Effective, but Pregabalin Markedly Relieved Pain. Clin Neuropharmacol, 2015; 38: 158-161.
    191. Inoue E, Watanabe Y, Xing J, Kushima I, Egawa J, Okuda S, Hoya S, Okada T, Uno Y, Ishizuka K, Sugimoto A, Igeta H, Nunokawa A, Sugiyama T, Ozaki N, Someya T. Resequencing and Association Analysis of CLN8 with Autism Spectrum Disorder in a Japanese Population. PLoS One, 2015; 10: e0144624.
    192. Ikeda M, Yoshimura R, Hashimoto R, Kondo K, Saito T, Shimasaki A, Ohi K, Tochigi M, Kawamura Y, Nishida N, Miyagawa T, Sasaki T, Tokunaga K, Kasai K, Takeda M, Nakamura J, Ozaki N, Iwata N. Genetic Overlap Between Antipsychotic Response and Susceptibility to Schizophrenia. J Clin Psychopharmacol, 2015; 35: 85-88.
    193. Hida H, Mouri A, Mori K, Matsumoto Y, Seki T, Taniguchi M, Yamada K, Iwamoto K, Ozaki N, Nabeshima T, Noda Y. Blonanserin Ameliorates Phencyclidine-Induced Visual-Recognition Memory Deficits: the Complex Mechanism of Blonanserin Action Involving D3-5-HT2A and D1-NMDA Receptors in the mPFC. Neuropsychopharmacology, 2015; 40: 601-613.
    194. Hayakawa N, Okada T, Nomura K, Tsukada T, Nakamura M. Is high job control a risk factor for poor quality of life in workers with high autism spectrum tendencies? A cross-sectional survey at a factory in Japan. J Occup Health, 2015; 57: 419-426.
    195. Hatano M, Ikeda M, Kondo K, Saito T, Shimasaki A, Esaki K, Umene-Nakano W, Yoshimura R, Nakamura J, Ozaki N, Iwata N. No support for replication of the genetic variants identified by a recent mega-analysis of the treatment response to antidepressants. J Hum Genet, 2015; 60: 343-344.
    196. Fujishiro H, Iritani S, Hattori M, Sekiguchi H, Matsunaga S, Habuchi C, Torii Y, Umeda K, Ozaki N, Yoshida M, Fujita K. Autopsy-confirmed hippocampal-sparing Alzheimer's disease with delusional jealousy as initial manifestation. Psychogeriatrics, 2015; 15: 198-203.
    197. Egawa J, Watanabe Y, Wang C, Inoue E, Sugimoto A, Sugiyama T, Igeta H, Nunokawa A, Shibuya M, Kushima I, Orime N, Hayashi T, Okada T, Uno Y, Ozaki N, Someya T. Novel Rare Missense Variations and Risk of Autism Spectrum Disorder: Whole-Exome Sequencing in Two Families with Affected Siblings and a Two-Stage Follow-Up Study in a Japanese Population. PLoS One, 2015; 10: e0119413.
    198. Xing J, Wang C, Kimura H, Takasaki Y, Kunimoto S, Yoshimi A, Nakamura Y, Koide T, Banno M, Kushima I, Uno Y, Okada T, Aleksic B, Ikeda M, Iwata N, Ozaki N. Resequencing and Association Analysis of PTPRA, a Possible Susceptibility Gene for Schizophrenia and Autism Spectrum Disorders. PLoS One, 2014; 9: e112531.
    199. Wang C, Koide T, Kimura H, Kunimoto S, Yoshimi A, Nakamura Y, Kushima I, Banno M, Kawano N, Takasaki Y, Xing J, Noda Y, Mouri A, Aleksic B, Ikeda M, Okada T, Iidaka T, Inada T, Iwata N, Ozaki N. Novel rare variants in F-box protein 45 (FBXO45) in schizophrenia. Schizophr Res, 2014; 157: 149-156.
    200. Uno Y, Mizukami H, Ando M, Yukihiro R, Iwasaki Y, Ozaki N. Reliability and Validity of the New Tanaka B Intelligence Scale Scores: A Group Intelligence Test. PLoS One, 2014; 9: e100262.
    201. Takahashi T, Nakamura Y, Nakamura Y, Aleksic B, Takayanagi Y, Furuichi A, Kido M, Nakamura M, Sasabayashi D, Ikeda M, Noguchi K, Kaibuchi K, Iwata N, Ozaki N, Suzuki M. The polymorphism of YWHAE, a gene encoding 14-3-3epsilon, and orbitofrontal sulcogyral pattern in patients with schizophrenia and healthy subjects. Prog Neuropsychopharmacol Biol Psychiatry, 2014; 51C: 166-171.
    202. Takahashi T, Nakamura M, Nakamura Y, Aleksic B, Kido M, Sasabayashi D, Takayanagi Y, Furuichi A, Nishikawa Y, Noguchi K, Ozaki N, Suzuki M. The Disrupted-in-Schizophrenia-1 Ser704Cys polymorphism and brain neurodevelopmental markers in schizophrenia and healthy subjects. Prog Neuropsychopharmacol Biol Psychiatry, 2014; 56C: 11-17.
    203. Shishido E, Aleksic B, Ozaki N. Copy-number variation in the pathogenesis of autism spectrum disorder. Psychiatry Clin Neurosci, 2014; 68: 85-95.
    204. Saito T, Kondo K, Iwayama Y, Shimasaki A, Aleksic B, Yamada K, Toyota T, Hattori E, Esaki K, Ujike H, Inada T, Kunugi H, Kato T, Yoshikawa T, Ozaki N, Ikeda M, Iwata N. Replication and cross-phenotype study based upon schizophrenia GWASs data in the Japanese population: Support for association of MHC region with psychosis. Am J Med Genet B Neuropsychiatr Genet, 2014; 165: 421-427.
    205. Ohoka H, Koide T, Goto S, Murase S, Kanai A, Masuda T, Aleksic B, Ishikawa N, Furumura K, Ozaki N. Effects of maternal depressive symptomatology during pregnancy and the postpartum period on infant-mother attachment. Psychiatry Clin Neurosci, 2014; 68: 631-639.
    206. Nishizawa D, Fukuda K, Kasai S, Hasegawa J, Aoki Y, Nishi A, Saita N, Koukita Y, Nagashima M, Katoh R, Satoh Y, Tagami M, Higuchi S, Ujike H, Ozaki N, Inada T, Iwata N, Sora I, Iyo M, Kondo N, Won MJ, Naruse N, Uehara-Aoyama K, Itokawa M, Koga M, Arinami T, Kaneko Y, Hayashida M, Ikeda K. Genome-wide association study identifies a potent locus associated with human opioid sensitivity. Mol Psychiatry, 2014; 19: 55-62.
    207. Morita T, Senzaki K, Ishihara R, Umeda K, Iwata N, Nagai T, Hida H, Nabeshima T, Yukawa K, Ozaki N, Noda Y. Plasma dehydroepiandrosterone sulfate levels in patients with major depressive disorder correlate with remission during treatment with antidepressants. Hum Psychopharmacol, 2014; 29: 280-286.
    208. Miyata S, Noda A, Iwamoto K, Takahashi M, Hara Y, Kojima J, Iidaka T, Ozaki N. The effects of acute treatment with paroxetine, amitriptyline, and placebo on the equilibrium function in healthy subjects: A double-blind crossover trial. Int J Psychiatry Clin Pract, 2014; 18: 32-36.
    209. Miyashita M, Arai M, Yuzawa H, Niizato K, Oshima K, Kushima I, Hashimoto R, Fukumoto M, Koike S, Toyota T, Ujike H, Arinami T, Kasai K, Takeda M, Ozaki N, Okazaki Y, Yoshikawa T, Amano N, Miyata T, Itokawa M. Replication of enhanced carbonyl stress in a subpopulation of schizophrenia. Psychiatry Clin Neurosci, 2014; 68: 83-84.
    210. Kubota C, Okada T, Aleksic B, Nakamura Y, Kunimoto S, Morikawa M, Shiino T, Tamaji A, Ohoka H, Banno N, Morita T, Murase S, Goto S, Kanai A, Masuda T, Ando M, Ozaki N. Factor structure of the Japanese version of the edinburgh postnatal depression scale in the postpartum period. PLoS One, 2014; 9: e103941.
    211. Kido M, Nakamura Y, Nemoto K, Takahashi T, Aleksic B, Furuichi A, Nakamura Y, Ikeda M, Noguchi K, Kaibuchi K, Iwata N, Ozaki N, Suzuki M. The Polymorphism of YWHAE, a Gene Encoding 14-3-3Epsilon, and Brain Morphology in Schizophrenia: A Voxel-Based Morphometric Study. PLoS One, 2014; 9: e103571.
    212. Katayama H, Kohmura K, Tanaka S, Imaeda M, Kawano N, Noda Y, Nishioka K, Ando M, Aleksic B, Iidaka T, Ozaki N. Social insecurity in relation to orbitofrontal activity in patients with eating disorders: a near-infrared spectroscopy study. BMC Psychiatry, 2014; 14: 173.
    213. Kajio Y, Kondo K, Saito T, Iwayama Y, Aleksic B, Yamada K, Toyota T, Hattori E, Ujike H, Inada T, Kunugi H, Kato T, Yoshikawa T, Ozaki N, Ikeda M, Iwata N. Genetic association study between the detected risk variants based upon type II diabetes GWAS and psychotic disorders in the Japanese population. J Hum Genet, 2014; 59: 54-56.
    214. Hida H, Mouri A, Ando Y, Mori K, Mamiya T, Iwamoto K, Ozaki N, Yamada K, Nabeshima T, Noda Y. Combination of neonatal PolyI:C and adolescent phencyclidine treatments is required to induce behavioral abnormalities with overexpression of GLAST in adult mice. Behav Brain Res, 2014; 258: 34-42.
    215. Hashimoto R, Ikeda M, Yamashita F, Ohi K, Yamamori H, Yasuda Y, Fujimoto M, Fukunaga M, Nemoto K, Takahashi T, Tochigi M, Onitsuka T, Yamasue H, Matsuo K, Iidaka T, Iwata N, Suzuki M, Takeda M, Kasai K, Ozaki N. Common variants at 1p36 are associated with superior frontal gyrus volume. Transl Psychiatry, 2014; 4: e472.
    216. De Rubeis S, He X, Goldberg AP, Poultney CS, Samocha K, Ercument Cicek A, Kou Y, Liu L, Fromer M, Walker S, Singh T, Klei L, Kosmicki J, Fu SC, Aleksic B, Biscaldi M, Bolton PF, Brownfeld JM, Cai J, Campbell NG, Carracedo A, Chahrour MH, Chiocchetti AG, Coon H, Crawford EL, Crooks L, Curran SR, Dawson G, Duketis E, Fernandez BA, Gallagher L, Geller E, Guter SJ, Sean Hill R, Ionita-Laza I, Jimenez Gonzalez P, Kilpinen H, Klauck SM, Kolevzon A, Lee I, Lei J, Lehtimaki T, Lin CF, Ma'ayan A, Marshall CR, McInnes AL, Neale B, Owen MJ, Ozaki N, Parellada M, Parr JR, Purcell S, Puura K, Rajagopalan D, Rehnstrom K, Reichenberg A, Sabo A, Sachse M, Sanders SJ, Schafer C, Schulte-Ruther M, Skuse D, Stevens C, Szatmari P, Tammimies K, Valladares O, Voran A, Wang LS, Weiss LA, Jeremy Willsey A, Yu TW, Yuen RK, Study DDD, Homozygosity Mapping Collaborative for A, Consortium UK, Autism Sequencing C, Cook EH, Freitag CM, Gill M, Hultman CM, Lehner T, Palotie A, Schellenberg GD, Sklar P, State MW, Sutcliffe JS, Walsh CA, Scherer SW, Zwick ME, Barrett JC, Cutler DJ, Roeder K, Devlin B, Daly MJ, Buxbaum JD. Synaptic, transcriptional and chromatin genes disrupted in autism. Nature, 2014; 515: 209-215.
    217. Adachi Y, Kimura H, Sato N, Nagashima W, Nakamura K, Aleksic B, Yoshida K, Fujimoto Y, Nakashima T, Ozaki N. Preoperative Level of Depression is a Predictor of Postoperative Levels of Depression in Patients with Head and Neck Cancer. Jpn J Clin Oncol, 2014; 44: 311-317.
    218. Watanabe Y, Iijima Y, Egawa J, Nunokawa A, Kaneko N, Arinami T, Ujike H, Inada T, Iwata N, Kunugi H, Itokawa M, Sasaki T, Ozaki N, Hashimoto R, Shibuya M, Igeta H, Someya T. Replication in a Japanese population that a MIR30E gene variation is associated with schizophrenia. Schizophr Res, 2013; 150: 596-597.
    219. Usami M, Okada T, Sasayama D, Iwadare Y, Watanabe K, Ushijima H, Kodaira M, Sugiyama N, Sawa T, Saito K. What time periods of the day are concerning for parents of children with attention deficit hyperactivity disorder? PLoS One, 2013; 8: e79806.
    220. Ukai K, Okajima A, Yamauchi A, Sasaki E, Yamaguchi Y, Kimura H, Aleksic B, Ozaki N. Total palliative care for a patient with multiple cerebral infarctions that occurred repeatedly in association with gastric cancer (Trousseau's syndrome). Palliat Support Care, 2013; 11: 169-172.
    221. Ukai K, Kimura H, Arao M, Aleksic B, Yamauchi A, Ishihara R, Iritani S, Kurita K, Ozaki N. Effectiveness of low-dose milnacipran for a patient suffering from pain disorder with delusional disorder (somatic type) in the orofacial region. Psychogeriatrics, 2013; 13: 99-102.
    222. Tanaka S, Syu A, Ishiguro H, Inada T, Horiuchi Y, Ishikawa M, Koga M, Noguchi E, Ozaki N, Someya T, Kakita A, Takahashi H, Nawa H, Arinami T. DPP6 as a candidate gene for neuroleptic-induced tardive dyskinesia. Pharmacogenomics J, 2013; 13: 27-34.
    223. Takata A, Iwayama Y, Fukuo Y, Ikeda M, Okochi T, Maekawa M, Toyota T, Yamada K, Hattori E, Ohnishi T, Toyoshima M, Ujike H, Inada T, Kunugi H, Ozaki N, Nanko S, Nakamura K, Mori N, Kanba S, Iwata N, Kato T, Yoshikawa T. A Population-Specific Uncommon Variant in GRIN3A Associated with Schizophrenia. Biol Psychiatry, 2013; 73: 532-539.
    224. Shiino T, Koide T, Kushima I, Ikeda M, Kunimoto S, Nakamura Y, Yoshimi A, Aleksic B, Banno M, Kikuchi T, Kohmura K, Adachi Y, Kawano N, Okada T, Inada T, Ujike H, Iidaka T, Suzuki M, Iwata N, Ozaki N. Common variants in bcl9 gene and schizophrenia in a japanese population: Association study, meta-analysis and cognitive function analysis. J Med Biochem, 2013; 32: 351-357.
    225. Shibata H, Yamamoto K, Sun Z, Oka A, Inoko H, Arinami T, Inada T, Ujike H, Itokawa M, Tochigi M, Watanabe Y, Someya T, Kunugi H, Suzuki T, Iwata N, Ozaki N, Fukumaki Y. Genome-wide association study of schizophrenia using microsatellite markers in the Japanese population. Psychiatr Genet, 2013; 23: 117-123.
    226. Seo S, Takayama K, Uno K, Ohi K, Hashimoto R, Nishizawa D, Ikeda K, Ozaki N, Nabeshima T, Miyamoto Y, Nitta A. Functional Analysis of Deep Intronic SNP rs13438494 in Intron 24 of PCLO Gene. PLoS One, 2013; 8: e76960.
    227. Sasada K, Iwamoto K, Kawano N, Kohmura K, Yamamoto M, Aleksic B, Ebe K, Noda Y, Ozaki N. Effects of repeated dosing with mirtazapine, trazodone, or placebo on driving performance and cognitive function in healthy volunteers. Hum Psychopharmacol, 2013; 28: 281-286.
    228. Niwa M, Jaaro-Peled H, Tankou S, Seshadri S, Hikida T, Matsumoto Y, Cascella NG, Kano S, Ozaki N, Nabeshima T, Sawa A. Adolescent stress-induced epigenetic control of dopaminergic neurons via glucocorticoids. Science, 2013; 339: 335-339.
    229. Miyata S, Noda A, Iwamoto K, Kawano N, Okuda M, Ozaki N. Poor sleep quality impairs cognitive performance in older adults. J Sleep Res, 2013; 22: 535-541.
    230. Miura H, Ando Y, Noda Y, Ozak N, Isobe K. Effects of Minocycline on Changes in Brain Tryptophan Metabolism and the Behavior of Juvenile Mice Elicited By Inescapable-Predator Stress. J Trauma Stress Disor Treat 2013; 2.
    231. Manchia M, Adli M, Akula N, Ardau R, Aubry JM, Backlund L, Banzato CE, Baune BT, Bellivier F, Bengesser S, Biernacka JM, Brichant-Petitjean C, Bui E, Calkin CV, Cheng AT, Chillotti C, Cichon S, Clark S, Czerski PM, Dantas C, Zompo MD, Depaulo JR, Detera-Wadleigh SD, Etain B, Falkai P, Frisen L, Frye MA, Fullerton J, Gard S, Garnham J, Goes FS, Grof P, Gruber O, Hashimoto R, Hauser J, Heilbronner U, Hoban R, Hou L, Jamain S, Kahn JP, Kassem L, Kato T, Kelsoe JR, Kittel-Schneider S, Kliwicki S, Kuo PH, Kusumi I, Laje G, Lavebratt C, Leboyer M, Leckband SG, Lopez Jaramillo CA, Maj M, Malafosse A, Martinsson L, Masui T, Mitchell PB, Mondimore F, Monteleone P, Nallet A, Neuner M, Novak T, O'Donovan C, Osby U, Ozaki N, Perlis RH, Pfennig A, Potash JB, Reich-Erkelenz D, Reif A, Reininghaus E, Richardson S, Rouleau GA, Rybakowski JK, Schalling M, Schofield PR, Schubert OK, Schweizer B, Seemuller F, Grigoroiu-Serbanescu M, Severino G, Seymour LR, Slaney C, Smoller JW, Squassina A, Stamm T, Steele J, Stopkova P, Tighe SK, Tortorella A, Turecki G, Wray NR, Wright A, Zandi PP, Zilles D, Bauer M, Rietschel M, McMahon FJ, Schulze TG, Alda M. Assessment of Response to Lithium Maintenance Treatment in Bipolar Disorder: A Consortium on Lithium Genetics (ConLiGen) Report. PLoS One, 2013; 8: e65636.
    232. Kondo K, Ikeda M, Kajio Y, Saito T, Iwayama Y, Aleksic B, Yamada K, Toyota T, Hattori E, Ujike H, Inada T, Kunugi H, Kato T, Yoshikawa T, Ozaki N, Iwata N. Genetic Variants on 3q21 and in the Sp8 Transcription Factor Gene (SP8) as Susceptibility Loci for Psychotic Disorders: A Genetic Association Study. PLoS One, 2013; 8: e70964.
    233. Kohmura K, Iwamoto K, Aleksic B, Sasada K, Kawano N, Katayama H, Noda Y, Noda A, Iidaka T, Ozaki N. Effects of sedative antidepressants on prefrontal cortex activity during verbal fluency task in healthy subjects: a near-infrared spectroscopy study. Psychopharmacology (Berl), 2013; 226: 75-81.
    234. Kawano N, Awata S, Ijuin M, Iwamoto K, Ozaki N. Necessity of normative data on the Japanese version of the Wechsler Memory Scale-Revised Logical Memory subtest for old-old people. Geriatr Gerontol Int, 2013; 13: 726-730.
    235. Kamijima K, Higuchi T, Ishigooka J, Ohmori T, Ozaki N, Kanba S, Kinoshita T, Koyama T, Group AS. Aripiprazole augmentation to antidepressant therapy in Japanese patients with major depressive disorder: A randomized, double-blind, placebo-controlled study (ADMIRE study). J Affect Disord, 2013; 151: 899-905.
    236. Iwamoto K, Kawano N, Sasada K, Kohmura K, Yamamoto M, Ebe K, Noda Y, Ozaki N. Effects of low-dose mirtazapine on driving performance in healthy volunteers. Hum Psychopharmacol, 2013; 28: 523-528.
    237. Ikeda M, Okahisa Y, Aleksic B, Won M, Kondo N, Naruse N, Aoyama-Uehara K, Sora I, Iyo M, Hashimoto R, Kawamura Y, Nishida N, Miyagawa T, Takeda M, Sasaki T, Tokunaga K, Ozaki N, Ujike H, Iwata N. Evidence for shared genetic risk between methamphetamine-induced psychosis and schizophrenia. Neuropsychopharmacology, 2013; 38: 1864-1870.
    238. Ikeda M, Aleksic B, Yamada K, Iwayama-Shigeno Y, Matsuo K, Numata S, Watanabe Y, Ohnuma T, Kaneko T, Fukuo Y, Okochi T, Toyota T, Hattori E, Shimodera S, Itakura M, Nunokawa A, Shibata N, Tanaka H, Yoneda H, Arai H, Someya T, Ohmori T, Yoshikawa T, Ozaki N, Iwata N. Genetic evidence for association between NOTCH4 and schizophrenia supported by a GWAS follow-up study in a Japanese population. Mol Psychiatry, 2013; 18: 636-638.
    239. Hashimoto R, Ikeda M, Ohi K, Yasuda Y, Yamamori H, Fukumoto M, Umeda-Yano S, Dickinson D, Aleksic B, Iwase M, Kazui H, Ozaki N, Weinberger DR, Iwata N, Takeda M. Genome-wide association study of cognitive decline in schizophrenia. Am J Psychiatry, 2013; 170: 683-684.
    240. Furukawa M, Tochigi M, Otowa T, Arinami T, Inada T, Ujike H, Watanabe Y, Iwata N, Itokawa M, Kunugi H, Hashimoto R, Ozaki N, Kakiuchi C, Kasai K, Sasaki T. An association analysis of the cardiomyopathy-associated 5 (CMYA5) gene with schizophrenia in a Japanese population. Psychiatr Genet, 2013; 23: 179-180.
    241. Esaki K, Kondo K, Hatano M, Saito T, Kishi T, Umene-Nakano W, Yoshimura R, Nakamura J, Ozaki N, Ikeda M, Iwata N. Further evidence of an association between a genetic variant in BMP7 and treatment response to SSRIs in major depressive disorder. J Hum Genet, 2013; 58: 568-569.
    242. Balan S, Yamada K, Iwayama Y, Toyota T, Ohnishi T, Maekawa M, Toyoshima M, Iwata Y, Suzuki K, Kikuchi M, Ujike H, Inada T, Kunugi H, Ozaki N, Iwata N, Nanko S, Kato T, Yoshikawa T. Lack of association of EGR2 variants with bipolar disorder in Japanese population. Gene, 2013; 526: 246-250.
    243. Asano M, Esaki K, Wakamatsu A, Kitajima T, Narita T, Naitoh H, Ozaki N, Iwata N. Maternal overprotection score of the Parental Bonding Instrument predicts the outcome of cognitive behavior therapy by trainees for depression. Psychiatry Clin Neurosci, 2013; 67: 340-344.
    244. Aleksic B, Kushima I, Ohye T, Ikeda M, Kunimoto S, Nakamura Y, Yoshimi A, Koide T, Iritani S, Kurahashi H, Iwata N, Ozaki N. Definition and refinement of the 7q36.3 duplication region associated with schizophrenia. Sci Rep, 2013; 3: 2587.
    245. Aleksic B, Kushima I, Hashimoto R, Ohi K, Ikeda M, Yoshimi A, Nakamura Y, Ito Y, Okochi T, Fukuo Y, Yasuda Y, Fukumoto M, Yamamori H, Ujike H, Suzuki M, Inada T, Takeda M, Kaibuchi K, Iwata N, Ozaki N. Analysis of the VAV3 as Candidate Gene for Schizophrenia: Evidences From Voxel-Based Morphometry and Mutation Screening. Schizophr Bull, 2013; 39: 720-728.
    246. Watanabe Y, Egawa J, Iijima Y, Nunokawa A, Kaneko N, Shibuya M, Arinami T, Ujike H, Inada T, Iwata N, Tochigi M, Kunugi H, Itokawa M, Ozaki N, Hashimoto R, Someya T. A two-stage case-control association study between the tryptophan hydroxylase 2 (TPH2) gene and schizophrenia in a Japanese population. Schizophr Res, 2012; 137: 264-266.
    247. Uno Y, Uchiyama T, Kurosawa M, Aleksic B, Ozaki N. The combined measles, mumps, and rubella vaccines and the total number of vaccines are not associated with development of autism spectrum disorder: The first case-control study in Asia. Vaccine, 2012; 30: 4292-4298.
    248. Torii Y, Iritani S, Sekiguchi H, Habuchi C, Hagikura M, Arai T, Ikeda K, Akiyama H, Ozaki N. Effects of aging on the morphologies of Heschl's gyrus and the superior temporal gyrus in schizophrenia: A postmortem study. Schizophr Res, 2012; 134: 137-142.
    249. Tokura T, Kimura H, Yoshimi A, Ohashi MS, Masuda M, Senzaki K, Yoshida K, Aleksic B, Noda Y, Yamada K, Ozaki N. Reliability and Validity of the Japanese Version of BEMIB Modified for Patients With Bipolar Disorder: a Self-rating Scale for Medication Adherence. Clinical Neuropsychopharmacology and Therapeutics, 2012; 3: 26-32.
    250. Tamaji A, Iwamoto K, Kawamura Y, Takahashi M, Ebe K, Kawano N, Kunimoto S, Aleksic B, Noda Y, Ozaki N. Differential effects of diazepam, tandospirone, and paroxetine on plasma brain-derived neurotrophic factor level under mental stress. Hum Psychopharmacol, 2012; 27: 329-333.
    251. Suzuki M, Takahashi S, Matsushima E, Tsunoda M, Kurachi M, Okada T, Hayashi T, Ishii Y, Morita K, Maeda H, Katayama S, Otsuka T, Hirayasu Y, Sekine M, Okubo Y, Motoshita M, Ohta K, Uchiyama M, Kojima T. Relationships between exploratory eye movement dysfunction and clinical symptoms in schizophrenia. Psychiatry Clin Neurosci, 2012; 66: 187-194.
    252. Okada T, Sato W, Kubota Y, Toichi M, Murai T. Right hemispheric dominance and interhemispheric cooperation in gaze-triggered reflexive shift of attention. Psychiatry Clin Neurosci, 2012; 66: 97-104.
    253. Ohi K, Hashimoto R, Yasuda Y, Fukumoto M, Yamamori H, Umeda-Yano S, Okada T, Kamino K, Morihara T, Iwase M, Kazui H, Numata S, Ikeda M, Ohnuma T, Iwata N, Ueno S, Ozaki N, Ohmori T, Arai H, Takeda M. Functional genetic variation at the NRGN gene and schizophrenia: Evidence from a gene-based case-control study and gene expression analysis. Am J Med Genet B Neuropsychiatr Genet, 2012; 159B: 405-413.
    254. Nakazaki C, Noda A, Koike Y, Yamada S, Murohara T, Ozaki N. Association of insomnia and short sleep duration with atherosclerosis risk in the elderly. Am J Hypertens, 2012; 25: 1149-1155.
    255. Nagashima W, Kimura H, Ito M, Tokura T, Arao M, Aleksic B, Yoshida K, Kurita K, Ozaki N. Effectiveness of duloxetine for the treatment of chronic nonorganic orofacial pain. Clin Neuropharmacol, 2012; 35: 273-277.
    256. Matsunaga S, Ikeda M, Kishi T, Fukuo Y, Aleksic B, Yoshimura R, Okochi T, Yamanouchi Y, Kinoshita Y, Kawashima K, Umene-Nakano W, Inada T, Kunugi H, Kato T, Yoshikawa T, Ujike H, Nakamura J, Ozaki N, Kitajima T, Iwata N. An evaluation of polymorphisms in casein kinase 1 delta and epsilon genes in major psychiatric disorders. Neurosci Lett, 2012; 529: 66-69.
    257. Kushima I, Nakamura Y, Aleksic B, Ikeda M, Ito Y, Shiino T, Okochi T, Fukuo Y, Ujike H, Suzuki M, Inada T, Hashimoto R, Takeda M, Kaibuchi K, Iwata N, Ozaki N. Resequencing and Association Analysis of the KALRN and EPHB1 Genes And Their Contribution to Schizophrenia Susceptibility. Schizophr Bull, 2012; 38: 552-560.
    258. Koide T, Banno M, Aleksic B, Yamashita S, Kikuchi T, Kohmura K, Adachi Y, Kawano N, Kushima I, Nakamura Y, Okada T, Ikeda M, Ohi K, Yasuda Y, Hashimoto R, Inada T, Ujike H, Iidaka T, Suzuki M, Takeda M, Iwata N, Ozaki N. Common Variants in MAGI2 Gene Are Associated with Increased Risk for Cognitive Impairment in Schizophrenic Patients. PLoS One, 2012; 7: e36836.
    259. Koide T, Aleksic B, Kikuchi T, Banno M, Kohmura K, Adachi Y, Kawano N, Iidaka T, Ozaki N. Evaluation of factors affecting continuous performance test identical pairs version score of schizophrenic patients in a Japanese clinical sample. Schizophr Res Treatment, 2012; 2012: 970131.
    260. Kitazawa M, Ohnuma T, Takebayashi Y, Shibata N, Baba H, Ohi K, Yasuda Y, Nakamura Y, Aleksic B, Yoshimi A, Okochi T, Ikeda M, Naitoh H, Hashimoto R, Iwata N, Ozaki N, Takeda M, Arai H. No associations found between the genes situated at 6p22.1, HIST1H2BJ, PRSS16, and PGBD1 in Japanese patients diagnosed with schizophrenia. Am J Med Genet B Neuropsychiatr Genet, 2012; 159B: 456-464.
    261. Kishi T, Ichinose H, Yoshimura R, Fukuo Y, Kitajima T, Inada T, Kunugi H, Kato T, Yoshikawa T, Ujike H, Musso GM, Umene-Nakano W, Nakamura J, Ozaki N, Iwata N. GTP cyclohydrolase 1 gene haplotypes as predictors of SSRI response in Japanese patients with major depressive disorder. J Affect Disord, 2012; 142: 315-322.
    262. Kishi T, Fukuo Y, Okochi T, Kawashima K, Kitajima T, Inada T, Ozaki N, Musso GM, Kane JM, Correll CU, Iwata N. Serotonin 6 receptor gene and schizophrenia: case-control study and meta-analysis. Hum Psychopharmacol, 2012; 27: 63-69.
    263. Kimura H, Yoshida K, Ito M, Tokura T, Nagashima W, Kurita K, Ozaki N. Plasma levels of milnacipran and its effectiveness for the treatment of chronic pain in the orofacial region. Hum Psychopharmacol, 2012; 27: 322-328.
    264. Kikuchi T, Iwamoto K, Sasada K, Aleksic B, Yoshida K, Ozaki N. Sexual dysfunction and hyperprolactinemia in Japanese schizophrenic patients taking antipsychotics. Prog Neuropsychopharmacol Biol Psychiatry, 2012; 37: 26-32.
    265. Kawano N, Iwamoto K, Ebe K, Suzuki Y, Hasegawa J, Ukai K, Umegaki H, Iidaka T, Ozaki N. Effects of mild cognitive impairment on driving performance in older drivers. J Am Geriatr Soc, 2012; 60: 1379-1381.
    266. Kawano N, Iwamoto K, Ebe K, Aleksic B, Noda A, Umegaki H, Kuzuya M, Iidaka T, Ozaki N. Slower adaptation to driving simulator and simulator sickness in older adults. Aging Clin Exp Res, 2012; 24: 285-289.
    267. Horiuchi Y, Iida S, Koga M, Ishiguro H, Iijima Y, Inada T, Watanabe Y, Someya T, Ujike H, Iwata N, Ozaki N, Kunugi H, Tochigi M, Itokawa M, Arai M, Niizato K, Iritani S, Kakita A, Takahashi H, Nawa H, Arinami T. Association of SNPs linked to increased expression of SLC1A1 with schizophrenia. Am J Med Genet B Neuropsychiatr Genet, 2012; 159B: 30-37.
    268. Hayakawa N, Koide T, Okada T, Murase S, Aleksic B, Furumura K, Shiino T, Nakamura Y, Tamaji A, Ishikawa N, Ohoka H, Usui H, Banno N, Morita T, Goto S, Kanai A, Masuda T, Ozaki N. The postpartum depressive state in relation to perceived rearing: a prospective cohort study. PLoS One, 2012; 7: e50220.
    269. Hagikura M, Iwamoto K, Aleksic B, Ozaki N. What is a rational antidepressant treatment for major depression in patients with Parkinson's disease? Psychiatry Clin Neurosci, 2012; 66: 463.
    270. Furumura K, Koide T, Okada T, Murase S, Aleksic B, Hayakawa N, Shiino T, Nakamura Y, Tamaji A, Ishikawa N, Ohoka H, Usui H, Banno N, Morita T, Goto S, Kanai A, Masuda T, Ozaki N. Prospective Study on the Association between Harm Avoidance and Postpartum Depressive State in a Maternal Cohort of Japanese Women. PLoS One, 2012; 7: e34725.
    271. Banno M, Koide T, Aleksic B, Okada T, Kikuchi T, Kohmura K, Adachi Y, Kawano N, Iidaka T, Ozaki N. Wisconsin Card Sorting Test scores and clinical and sociodemographic correlates in Schizophrenia: multiple logistic regression analysis. BMJ Open, 2012; 2.
    272. Adachi Y, Aleksic B, Nobata R, Suzuki T, Yoshida K, Ono Y, Ozaki N. Combination use of Beck Depression Inventory and two-question case-finding instrument as a screening tool for depression in the workplace. BMJ Open, 2012; 2.
    273. Yoshimura T, Usui H, Takahashi N, Yoshimi A, Saito S, Aleksic B, Ujike H, Inada T, Yamada M, Uchimura N, Iwata N, Sora I, Iyo M, Ozaki N. Association analysis of the GDNF gene with methamphetamine use disorder in a Japanese population. Prog Neuropsychopharmacol Biol Psychiatry, 2011; 35: 1268-1272.
    274. Yokobayashi E, Ujike H, Kotaka T, Okahisa Y, Takaki M, Kodama M, Inada T, Uchimura N, Yamada M, Iwata N, Iyo M, Sora I, Ozaki N, Kuroda S. Association study of serine racemase gene with methamphetamine psychosis. Curr Neuropharmacol, 2011; 9: 169-175.
    275. Ujike H, Kishimoto M, Okahisa Y, Kodama M, Takaki M, Inada T, Uchimura N, Yamada M, Iwata N, Iyo M, Sora I, Ozaki N. Association Between 5HT1b Receptor Gene and Methamphetamine Dependence. Curr Neuropharmacol, 2011; 9: 163-168.
    276. Tsunoka T, Kishi T, Ikeda M, Kitajima T, Yamanouchi Y, Kinoshita Y, Kawashima K, Okochi T, Okumura T, Inada T, Ujike H, Yamada M, Uchimura N, Sora I, Iyo M, Ozaki N, Iwata N. No Association Between GRM3 and Japanese Methamphetamine-Induced Psychosis. Curr Neuropharmacol, 2011; 9: 160-162.
    277. Tsunoda A, Iritani S, Ozaki N. Presenile dementia diagnosed as posterior cortical atrophy. Psychogeriatrics, 2011; 11: 171-176.
    278. Takata A, Kim SH, Ozaki N, Iwata N, Kunugi H, Inada T, Ujike H, Nakamura K, Mori N, Ahn YM, Joo EJ, Song JY, Kanba S, Yoshikawa T, Kim YS, Kato T. Association of ANK3 with bipolar disorder confirmed in East Asia. Am J Med Genet B Neuropsychiatr Genet, 2011; 156: 312-315.
    279. Takahashi N, Nielsen KS, Aleksic B, Petersen S, Ikeda M, Kushima I, Vacaresse N, Ujike H, Iwata N, Dubreuil V, Mirza N, Sakurai T, Ozaki N, Buxbaum JD, Sap J. Loss of Function Studies in Mice and Genetic Association Link Receptor Protein Tyrosine Phosphatase alpha to Schizophrenia. Biol Psychiatry, 2011; 70: 626-635.
    280. Sekiguchi H, Iritani S, Habuchi C, Torii Y, Kuroda K, Kaibuchi K, Ozaki N. Impairment of the tyrosine hydroxylase neuronal network in the orbitofrontal cortex of a genetically modified mouse model of schizophrenia. Brain Res, 2011; 1392: 47-53.
    281. Okumura T, Okochi T, Kishi T, Ikeda M, Kitajima T, Kinoshita Y, Kawashima K, Tsunoka T, Fukuo Y, Inada T, Yamada M, Uchimura N, Iyo M, Sora I, Ozaki N, Ujike H, Iwata N. Genetic Association Analysis of NOS1 and Methamphetamine-Induced Psychosis Among Japanese. Curr Neuropharmacol, 2011; 9: 155-159.
    282. Okochi T, Kishi T, Ikeda M, Kitajima T, Kinoshita Y, Kawashima K, Okumura T, Tsunoka T, Fukuo Y, Inada T, Yamada M, Uchimura N, Iyo M, Sora I, Ozaki N, Ujike H, Iwata N. Genetic Association Analysis of NOS3 and Methamphetamine-Induced Psychosis Among Japanese. Curr Neuropharmacol, 2011; 9: 151-154.
    283. Okahisa Y, Kodama M, Takaki M, Inada T, Uchimura N, Yamada M, Iwata N, Iyo M, Sora I, Ozaki N, Ujike H. Association between the Regulator of G-protein Signaling 9 Gene and Patients with Methamphetamine Use Disorder and Schizophrenia. Curr Neuropharmacol, 2011; 9: 190-194.
    284. Okahisa Y, Kodama M, Takaki M, Inada T, Uchimura N, Yamada M, Iwata N, Iyo M, Sora I, Ozaki N, Ujike H. Association Study of Two Cannabinoid Receptor Genes, CNR1 and CNR2, with Methamphetamine Dependence. Curr Neuropharmacol, 2011; 9: 183-189.
    285. Ogasawara K, Nakamura Y, Aleksic B, Yoshida K, Ando K, Iwata N, Kayukawa Y, Ozaki N. Depression associated with alcohol intake and younger age in Japanese office workers: a case-control and a cohort study. J Affect Disord, 2011; 128: 33-40.
    286. Niwa M, Matsumoto Y, Mouri A, Ozaki N, Nabeshima T. Vulnerability in early life to changes in the rearing environment plays a crucial role in the aetiopathology of psychiatric disorders. Int J Neuropsychopharmacol, 2011; 14: 459-477.
    287. Miura H, Ando Y, Noda Y, Isobe K, Ozaki N. Long-lasting effects of inescapable-predator stress on brain tryptophan metabolism and the behavior of juvenile mice. Stress, 2011; 14: 262-272.
    288. Kubota Y, Takasu NN, Horita S, Kondo M, Shimizu M, Okada T, Wakamura T, Toichi M. Dorsolateral prefrontal cortical oxygenation during REM sleep in humans. Brain Res, 2011; 1389: 83-92.
    289. Kobayashi H, Ujike H, Iwata N, Inada T, Yamada M, Sekine Y, Uchimura N, Iyo M, Ozaki N, Itokawa M, Sora I. Association analysis of the tryptophan hydroxylase 2 gene polymorphisms in patients with methamphetamine dependence/psychosis. Curr Neuropharmacol, 2011; 9: 176-182.
    290. Kobayashi H, Ujike H, Iwata N, Inada T, Yamada M, Sekine Y, Uchimura N, Iyo M, Ozaki N, Itokawa M, Sora I. Association analysis of the adenosine A1 receptor gene polymorphisms in patients with methamphetamine dependence/psychosis. Curr Neuropharmacol, 2011; 9: 137-142.
    291. Kishi T, Yoshimura R, Fukuo Y, Kitajima T, Okochi T, Matsunaga S, Inada T, Kunugi H, Kato T, Yoshikawa T, Ujike H, Umene-Nakano W, Nakamura J, Ozaki N, Serretti A, Correll CU, Iwata N. The CLOCK Gene and Mood Disorders: A Case-Control Study and Meta-analysis. Chronobiol Int, 2011; 28: 825-833.
    292. Kishi T, Okochi T, Tsunoka T, Okumura T, Kitajima T, Kawashima K, Yamanouchi Y, Kinoshita Y, Naitoh H, Inada T, Kunugi H, Kato T, Yoshikawa T, Ujike H, Ozaki N, Iwata N. Serotonin 1A receptor gene, schizophrenia and bipolar disorder: An association study and meta-analysis. Psychiatry Res, 2011; 185: 20-26.
    293. Kishi T, Okochi T, Kitajima T, Ujike H, Inada T, Yamada M, Uchimura N, Sora I, Iyo M, Ozaki N, Correll CU, Iwata N. Lack of association between translin-associated factor X gene (TSNAX) and methamphetamine dependence in the Japanese population. Prog Neuropsychopharmacol Biol Psychiatry, 2011; 35: 1618-1622.
    294. Kishi T, Kitajima T, Tsunoka T, Okumura T, Kawashima K, Okochi T, Yamanouchi Y, Kinoshita Y, Ujike H, Inada T, Yamada M, Uchimura N, Sora I, Iyo M, Ozaki N, Iwata N. Lack of association between prokineticin 2 gene and Japanese methamphetamine dependence. Curr Neuropharmacol, 2011; 9: 133-136.
    295. Kishi T, Kitajima T, Kawashima K, Okochi T, Yamanouchi Y, Kinoshita Y, Ujike H, Inada T, Yamada M, Uchimura N, Sora I, Iyo M, Ozaki N, Iwata N. Association Analysis of Nuclear Receptor Rev-erb Alpha Gene (NR1D1) and Japanese Methamphetamine Dependence. Curr Neuropharmacol, 2011; 9: 129-132.
    296. Kishi T, Fukuo Y, Okochi T, Kitajima T, Ujike H, Inada T, Yamada M, Uchimura N, Sora I, Iyo M, Ozaki N, Correll CU, Iwata N. No significant association between SIRT1 gene and methamphetamine-induced psychosis in the Japanese population. Hum Psychopharmacol, 2011; 26: 445-450.
    297. Kishi T, Fukuo Y, Okochi T, Kitajima T, Kawashima K, Naitoh H, Ujike H, Inada T, Yamada M, Uchimura N, Sora I, Iyo M, Ozaki N, Iwata N. Serotonin 6 receptor gene is associated with methamphetamine-induced psychosis in a Japanese population. Drug Alcohol Depend, 2011; 113: 1-7.
    298. Kishi T, Fukuo Y, Kitajima T, Okochi T, Yamanouchi Y, Kinoshita Y, Kawashima K, Inada T, Kunugi H, Kato T, Yoshikawa T, Ujike H, Ozaki N, Iwata N. SIRT1 gene, schizophrenia and bipolar disorder in the Japanese population: an association study. Genes Brain Behav, 2011; 10: 257-263.
    299. Kikuchi T, Iwamoto K, Sasada K, Aleksic B, Yoshida K, Ozaki N. Reliability and validity of a new sexual function questionnaire (Nagoya Sexual Function Questionnaire) for schizophrenic patients taking antipsychotics. Hum Psychopharmacol, 2011; 26: 300-306.
    300. Ishikawa N, Goto S, Murase S, Kanai A, Masuda T, Aleksic B, Usui H, Ozaki N. Prospective study of maternal depressive symptomatology among Japanese women. J Psychosom Res, 2011; 71: 264-269.
    301. Ikeda M, Aleksic B, Kinoshita Y, Okochi T, Kawashima K, Kushima I, Ito Y, Nakamura Y, Kishi T, Okumura T, Fukuo Y, Williams HJ, Hamshere ML, Ivanov D, Inada T, Suzuki M, Hashimoto R, Ujike H, Takeda M, Craddock N, Kaibuchi K, Owen MJ, Ozaki N, O'Donovan MC, Iwata N. Genome-wide association study of schizophrenia in a Japanese population. Biol Psychiatry, 2011; 69: 472-478.
    302. Iijima Y, Aleksic B, Ozaki N. Necessity for ethical consideration of research in the aftermath of disaster. Psychiatry Clin Neurosci, 2011; 65: 535-536.
    303. Hironaka M, Kotani T, Sumigama S, Tsuda H, Mano Y, Hayakawa H, Tanaka S, Ozaki N, Tamakoshi K, Kikkawa F. Maternal mental disorders and pregnancy outcomes: A clinical study in a Japanese population. J Obstet Gynaecol Res, 2011; 37: 1283-1289.
    304. Hashimoto R, Ohi K, Yasuda Y, Fukumoto M, Yamamori H, Takahashi H, Iwase M, Okochi T, Kazui H, Saitoh O, Tatsumi M, Iwata N, Ozaki N, Kamijima K, Kunugi H, Takeda M. Variants of the RELA gene are associated with schizophrenia and their startle responses. Neuropsychopharmacology, 2011; 36: 1921-1931.
    305. Hashimoto R, Ohi K, Yasuda Y, Fukumoto M, Yamamori H, Kamino K, Morihara T, Iwase M, Kazui H, Numata S, Ikeda M, Ueno S, Ohmori T, Iwata N, Ozaki N, Takeda M. No association between the PCM1 gene and schizophrenia: A multi-center case-control study and a meta-analysis. Schizophr Res, 2011; 129: 80-84.
    306. Habuchi C, Iritani S, Sekiguchi H, Torii Y, Ishihara R, Arai T, Hasegawa M, Tsuchiya K, Akiyama H, Shibayama H, Ozaki N. Clinicopathological study of diffuse neurofibrillary tangles with calcification With special reference to TDP-43 proteinopathy and alpha-synucleinopathy. J Neurol Sci, 2011; 301: 77-85.
    307. Fukuo Y, Kishi T, Kushima I, Yoshimura R, Okochi T, Kitajima T, Matsunaga S, Kawashima K, Umene-Nakano W, Naitoh H, Inada T, Nakamura J, Ozaki N, Iwata N. Possible association between ubiquitin-specific peptidase 46 gene and major depressive disorders in the Japanese population. J Affect Disord, 2011; 133: 150-157.
    308. Fuchikami M, Morinobu S, Segawa M, Okamoto Y, Yamawaki S, Ozaki N, Inoue T, Kusumi I, Koyama T, Tsuchiyama K, Terao T. DNA methylation profiles of the brain-derived neurotrophic factor (BDNF) gene as a potent diagnostic biomarker in major depression. PLoS One, 2011; 6: e23881.
    309. Deng X, Takaki H, Wang L, Kuroki T, Nakahara T, Hashimoto K, Ninomiya H, Arinami T, Inada T, Ujike H, Itokawa M, Tochigi M, Watanabe Y, Someya T, Kunugi H, Iwata N, Ozaki N, Shibata H, Fukumaki Y. Positive association of Phencyclidine-responsive genes, PDE4A and PLAT, with schizophrenia. Am J Med Genet B Neuropsychiatr Genet, 2011; 156: 850-858.
    310. Banno M, Koide T, Aleksic B, Yamada K, Kikuchi T, Kohmura K, Adachi Y, Kawano N, Kushima I, Ikeda M, Inada T, Yoshikawa T, Iwata N, Ozaki N. A case control association study and cognitive function analysis of neuropilin and tolloid-like 1 gene and schizophrenia in the Japanese population. PLoS One, 2011; 6: e28929.
    311. Yoshimi A, Aleksic B, Kawamura Y, Takahashi N, Yamada S, Usui H, Saito S, Ito Y, Iwata N, Inada T, Noda Y, Yamada K, Ozaki N. Gene-wide association study between the methylenetetrahydrofolate reductase gene (MTHFR) and schizophrenia in the Japanese population, with an updated meta-analysis on currently available data. Schizophr Res, 2010; 124: 216-222.
    312. Yazaki S, Koga M, Ishiguro H, Inada T, Ujike H, Itokawa M, Otowa T, Watanabe Y, Someya T, Iwata N, Kunugi H, Ozaki N, Arinami T. An association study between the dymeclin gene and schizophrenia in the Japanese population. J Hum Genet, 2010; 55: 631-634.
    313. Ukai K, Matsuo K, Nakamura R, Sobue G, Kosaka K, Shibayama H, Iritani S, Ishihara R, Ozaki N. A case of dementia with Lewy bodies that temporarily showed symptoms similar to Creutzfeldt-Jakob disease. Psychogeriatrics, 2010; 10: 201-205.
    314. Tsunoka T, Kishi T, Kitajima T, Okochi T, Okumura T, Yamanouchi Y, Kinoshita Y, Kawashima K, Naitoh H, Inada T, Ujike H, Yamada M, Uchimura N, Sora I, Iyo M, Ozaki N, Iwata N. Association analysis of GRM2 and HTR2A with methamphetamine-induced psychosis and schizophrenia in the Japanese population. Prog Neuropsychopharmacol Biol Psychiatry, 2010; 34: 639-644.
    315. Tomida K, Takahashi N, Saito S, Maeno N, Iwamoto K, Yoshida K, Kimura H, Iidaka T, Ozaki N. Relationship of psychopathological symptoms and cognitive function to subjective quality of life in patients with chronic schizophrenia. Psychiatry Clin Neurosci, 2010; 64: 62-69.
    316. Takahashi M, Iwamoto K, Kawamura Y, Nakamura Y, Ishihara R, Uchiyama Y, Ebe K, Noda A, Noda Y, Yoshida K, Iidaka T, Ozaki N. The effects of acute treatment with tandospirone, diazepam, and placebo on driving performance and cognitive function in healthy volunteers. Hum Psychopharmacol, 2010; 25: 260-267.
    317. Takahashi M, Iwamoto K, Fukatsu H, Naganawa S, Iidaka T, Ozaki N. White matter microstructure of the cingulum and cerebellar peduncle is related to sustained attention and working memory: a diffusion tensor imaging study. Neurosci Lett, 2010; 477: 72-76.
    318. Takahashi M, Hayashi H, Watanabe Y, Sawamura K, Fukui N, Watanabe J, Kitajima T, Yamanouchi Y, Iwata N, Mizukami K, Hori T, Shimoda K, Ujike H, Ozaki N, Iijima K, Takemura K, Aoshima H, Someya T. Diagnostic classification of schizophrenia by neural network analysis of blood-based gene expression signatures. Schizophr Res, 2010; 119: 210-218.
    319. Syu A, Ishiguro H, Inada T, Horiuchi Y, Tanaka S, Ishikawa M, Arai M, Itokawa M, Niizato K, Iritani S, Ozaki N, Takahashi M, Kakita A, Takahashi H, Nawa H, Keino-Masu K, Arikawa-Hirasawa E, Arinami T. Association of the HSPG2 gene with neuroleptic-induced tardive Dyskinesia. Neuropsychopharmacology, 2010; 35: 1155-1164.
    320. Schulze TG, Alda M, Adli M, Akula N, Ardau R, Bui ET, Chillotti C, Cichon S, Czerski P, Del Zompo M, Detera-Wadleigh SD, Grof P, Gruber O, Hashimoto R, Hauser J, Hoban R, Iwata N, Kassem L, Kato T, Kittel-Schneider S, Kliwicki S, Kelsoe JR, Kusumi I, Laje G, Leckband SG, Manchia M, Macqueen G, Masui T, Ozaki N, Perlis RH, Pfennig A, Piccardi P, Richardson S, Rouleau G, Reif A, Rybakowski JK, Sasse J, Schumacher J, Severino G, Smoller JW, Squassina A, Turecki G, Young LT, Yoshikawa T, Bauer M, McMahon FJ. The International Consortium on Lithium Genetics (ConLiGen): An Initiative by the NIMH and IGSLI to Study the Genetic Basis of Response to Lithium Treatment. Neuropsychobiology, 2010; 62: 72-78.
    321. Okuda A, Suzuki T, Kishi T, Yamanouchi Y, Umeda K, Haitoh H, Hashimoto S, Ozaki N, Iwata N. Duration of untreated illness and antidepressant fluvoxamine response in major depressive disorder. Psychiatry Clin Neurosci, 2010; 64: 268-273.
    322. Okuda A, Kishi T, Okochi T, Ikeda M, Kitajima T, Tsunoka T, Okumukura T, Fukuo Y, Kinoshita Y, Kawashima K, Yamanouchi Y, Inada T, Ozaki N, Iwata N. Translin-associated factor X gene (TSNAX) may be associated with female major depressive disorder in the Japanese population. Neuromolecular Med, 2010; 12: 78-85.
    323. Ohnuma T, Shibata N, Baba H, Ohi K, Yasuda Y, Nakamura Y, Okochi T, Naitoh H, Hashimoto R, Iwata N, Ozaki N, Takeda M, Arai H. No association between DAO and schizophrenia in a Japanese patient population: a multicenter replication study. Schizophr Res, 2010; 118: 300-302.
    324. Ohi K, Hashimoto R, Yasuda Y, Yoshida T, Takahashi H, Iike N, Iwase M, Kamino K, Ishii R, Kazui H, Fukumoto M, Takamura H, Yamamori H, Azechi M, Ikezawa K, Tanimukai H, Tagami S, Morihara T, Okochi M, Yamada K, Numata S, Ikeda M, Tanaka T, Kudo T, Ueno S, Yoshikawa T, Ohmori T, Iwata N, Ozaki N, Takeda M. The chitinase 3-like 1 gene and schizophrenia: evidence from a multi-center case-control study and meta-analysis. Schizophr Res, 2010; 116: 126-132.
    325. Nunokawa A, Watanabe Y, Kaneko N, Sugai T, Yazaki S, Arinami T, Ujike H, Inada T, Iwata N, Kunugi H, Sasaki T, Itokawa M, Ozaki N, Hashimoto R, Someya T. The dopamine D3 receptor (DRD3) gene and risk of schizophrenia: case-control studies and an updated meta-analysis. Schizophr Res, 2010; 116: 61-67.
    326. Noda Y, Mouri A, Ando Y, Waki Y, Yamada SN, Yoshimi A, Yamada K, Ozaki N, Wang D, Nabeshima T. Galantamine ameliorates the impairment of recognition memory in mice repeatedly treated with methamphetamine: involvement of allosteric potentiation of nicotinic acetylcholine receptors and dopaminergic-ERK1/2 systems. Int J Neuropsychopharmacol, 2010; 13: 1343-1354.
    327. Nishiyama T, Ozaki N. Measurement limit of quality-of-life questionnaires in psychiatric settings. Qual Life Res, 2010; 19: 25-30.
    328. Nakamura Y, Ito Y, Aleksic B, Kushima I, Yasui-Furukori N, Inada T, Ono Y, Ozaki N. Influence of HTR2A polymorphisms and parental rearing on personality traits in healthy Japanese subjects. J Hum Genet, 2010; 55: 838-841.
    329. Morikawa T, Manabe T, Ito Y, Yamada S, Yoshimi A, Nagai T, Ozaki N, Mayeda A. The expression of HMGA1a is increased in lymphoblastoid cell lines from schizophrenia patients. Neurochem Int, 2010; 56: 736-739.
    330. Miyata S, Noda A, Ozaki N, Hara Y, Minoshima M, Iwamoto K, Takahashi M, Iidaka T, Koike Y. Insufficient sleep impairs driving performance and cognitive function. Neurosci Lett, 2010; 469: 229-233.
    331. Kushima I, Aleksic B, Ito Y, Nakamura Y, Nakamura K, Mori N, Kikuchi M, Inada T, Kunugi H, Nanko S, Kato T, Yoshikawa T, Ujike H, Suzuki M, Iwata N, Ozaki N. Association study of ubiquitin-specific peptidase 46 (USP46) with bipolar disorder and schizophrenia in a Japanese population. J Hum Genet, 2010; 55: 133-136.
    332. Kushima I, Aleksic B, Ikeda M, Yamanouchi Y, Kinoshita Y, Ito Y, Nakamura Y, Inada T, Iwata N, Ozaki N. Association study of bromodomain-containing 1 gene with schizophrenia in Japanese population. Am J Med Genet B Neuropsychiatr Genet, 2010; 153B: 786-791.
    333. Koide T, Aleksic B, Ito Y, Usui H, Yoshimi A, Inada T, Suzuki M, Hashimoto R, Takeda M, Iwata N, Ozaki N. A two-stage case-control association study of the dihydropyrimidinase-like 2 gene (DPYSL2) with schizophrenia in Japanese subjects. J Hum Genet, 2010; 55: 469-472.
    334. Kobayashi H, Ujike H, Iwata N, Inada T, Yamada M, Sekine Y, Uchimura N, Iyo M, Ozaki N, Itokawa M, Sora I. The adenosine A2A receptor is associated with methamphetamine dependence/psychosis in the Japanese population. Behav Brain Funct, 2010; 6: 50.
    335. Kishi T, Yoshimura R, Okochi T, Fukuo Y, Kitajima T, Okumura T, Tsunoka T, Kawashima K, Yamanouchi Y, Kinoshita Y, Umene-Nakano W, Naitoh H, Nakamura J, Ozaki N, Iwata N. Association analysis of SIGMAR1 with major depressive disorder and SSRI response. Neuropharmacology, 2010; 58: 1168-1173.
    336. Kishi T, Yoshimura R, Kitajima T, Okochi T, Okumura T, Tsunoka T, Yamanouchi Y, Kinoshita Y, Kawashima K, Naitoh H, Nakamura J, Ozaki N, Iwata N. HTR2A is associated with SSRI response in Major Depressive Disorder in a Japanese cohort. Neuromolecular Med, 2010; 12: 237-242.
    337. Kishi T, Yoshimura R, Kitajima T, Okochi T, Okumura T, Tsunoka T, Yamanouchi Y, Kinoshita Y, Kawashima K, Fukuo Y, Naitoh H, Umene-Nakano W, Inada T, Nakamura J, Ozaki N, Iwata N. SIRT1 gene is associated with major depressive disorder in the Japanese population. J Affect Disord, 2010; 126: 167-173.
    338. Kishi T, Tsunoka T, Ikeda M, Kitajima T, Kawashima K, Okochi T, Okumura T, Yamanouchi Y, Kinoshita Y, Ujike H, Inada T, Yamada M, Uchimura N, Sora I, Iyo M, Ozaki N, Iwata N. Serotonin 1A receptor gene is associated with Japanese methamphetamine-induced psychosis patients. Neuropharmacology, 2010; 58: 452-456.
    339. Kishi T, Kitajima T, Tsunoka T, Okumura T, Okochi T, Kawashima K, Inada T, Ujike H, Yamada M, Uchimura N, Sora I, Iyo M, Ozaki N, Iwata N. PROKR2 is associated with methamphetamine dependence in the Japanese population. Prog Neuropsychopharmacol Biol Psychiatry, 2010; 34: 1033-1036.
    340. Kishi T, Fukuo Y, Yoshimura R, Okochi T, Kitajima T, Naitoh H, Umene-Nakano W, Nakamura J, Ozaki N, Iwata N. Pharmacogenetic study of serotonin 6 receptor gene with antidepressant response in major depressive disorder in the Japanese population. Hum Psychopharmacol, 2010; 25: 481-486.
    341. Iwayama Y, Hattori E, Maekawa M, Yamada K, Toyota T, Ohnishi T, Iwata Y, Tsuchiya KJ, Sugihara G, Kikuchi M, Hashimoto K, Iyo M, Inada T, Kunugi H, Ozaki N, Iwata N, Nanko S, Iwamoto K, Okazaki Y, Kato T, Yoshikawa T. Association analyses between brain-expressed fatty-acid binding protein (FABP) genes and schizophrenia and bipolar disorder. Am J Med Genet B Neuropsychiatr Genet, 2010; 153B: 484-493.
    342. Ito M, Kimura H, Yoshida K, Kimura Y, Ozaki N, Kurita K. Effectiveness of milnacipran for the treatment of chronic pain in the orofacial region. Clin Neuropharmacol, 2010; 33: 79-83.
    343. Ishiguro H, Koga M, Horiuchi Y, Noguchi E, Morikawa M, Suzuki Y, Arai M, Niizato K, Iritani S, Itokawa M, Inada T, Iwata N, Ozaki N, Ujike H, Kunugi H, Sasaki T, Takahashi M, Watanabe Y, Someya T, Kakita A, Takahashi H, Nawa H, Arinami T. Supportive evidence for reduced expression of GNB1L in schizophrenia. Schizophr Bull, 2010; 36: 756-765.
    344. Ishiguro H, Horiuchi Y, Ishikawa M, Koga M, Imai K, Suzuki Y, Morikawa M, Inada T, Watanabe Y, Takahashi M, Someya T, Ujike H, Iwata N, Ozaki N, Onaivi ES, Kunugi H, Sasaki T, Itokawa M, Arai M, Niizato K, Iritani S, Naka I, Ohashi J, Kakita A, Takahashi H, Nawa H, Arinami T. Brain cannabinoid CB2 receptor in schizophrenia. Biol Psychiatry, 2010; 67: 974-982.
    345. Iritani S, Sekiguchi H, Habuchi C, Torii Y, Yamada S, Waki Y, Noda Y, Furukawa H, Nabeshima T, Ozaki N. Immunohistochemical study of vesicle monoamine transporter 2 in the hippocampal formation of PCP-treated mice. Neurosci Res, 2010; 68: 125-130.
    346. Iritani S, Sekiguchi H, Habuchi C, Hikita T, Taya S, Kaibuchi K, Ozaki N. Immunohistochemical study of vesicle monoamine transporter 2 in the hippocampal region of genetic animal model of schizophrenia. Synapse, 2010; 64: 948-953.
    347. Ikeda M, Tomita Y, Mouri A, Koga M, Okochi T, Yoshimura R, Yamanouchi Y, Kinoshita Y, Hashimoto R, Williams HJ, Takeda M, Nakamura J, Nabeshima T, Owen MJ, O'Donovan MC, Honda H, Arinami T, Ozaki N, Iwata N. Identification of novel candidate genes for treatment response to risperidone and susceptibility for schizophrenia: integrated analysis among pharmacogenomics, mouse expression, and genetic case-control association approaches. Biol Psychiatry, 2010; 67: 263-269.
    348. Ikeda M, Aleksic B, Kirov G, Kinoshita Y, Yamanouchi Y, Kitajima T, Kawashima K, Okochi T, Kishi T, Zaharieva I, Owen MJ, O'Donovan MC, Ozaki N, Iwata N. Copy number variation in schizophrenia in the Japanese population. Biol Psychiatry, 2010; 67: 283-286.
    349. Iidaka T, Saito DN, Komeda H, Mano Y, Kanayama N, Osumi T, Ozaki N, Sadato N. Transient neural activation in human amygdala involved in aversive conditioning of face and voice. J Cogn Neurosci, 2010; 22: 2074-2085.
    350. Hashimoto R, Noguchi H, Hori H, Nakabayashi T, Suzuki T, Iwata N, Ozaki N, Kosuga A, Tatsumi M, Kamijima K, Harada S, Takeda M, Saitoh O, Kunugi H. A genetic variation in the dysbindin gene (DTNBP1) is associated with memory performance in healthy controls. World J Biol Psychiatry, 2010; 11: 431-438.
    351. Hashimoto R, Hashimoto H, Shintani N, Ohi K, Hori H, Saitoh O, Kosuga A, Tatsumi M, Iwata N, Ozaki N, Kamijima K, Baba A, Takeda M, Kunugi H. Possible association between the pituitary adenylate cyclase-activating polypeptide (PACAP) gene and major depressive disorder. Neurosci Lett, 2010; 468: 300-302.
    352. Fukuo Y, Kishi T, Yoshimura R, Kitajima T, Okochi T, Yamanouchi Y, Kinoshita Y, Kawashima K, Naitoh H, Umene-Nakano W, Inada T, Kunugi H, Kato T, Yoshikawa T, Ujike H, Nakamura J, Ozaki N, Iwata N. Serotonin 6 receptor gene and mood disorders: case-control study and meta-analysis. Neurosci Res, 2010; 67: 250-255.
    353. Fukuo Y, Kishi T, Okochi T, Kitajima T, Tsunoka T, Okumukura T, Kinoshita Y, Kawashima K, Yamanouchi Y, Umene-Nakano W, Naitoh H, Inada T, Yoshimura R, Nakamura J, Ozaki N, Iwata N. Lack of Association Between MAGEL2 and Schizophrenia and Mood Disorders in the Japanese Population. Neuromolecular Med, 2010; 12: 285-291.
    354. Amagane H, Watanabe Y, Kaneko N, Nunokawa A, Muratake T, Ishiguro H, Arinami T, Ujike H, Inada T, Iwata N, Kunugi H, Sasaki T, Hashimoto R, Itokawa M, Ozaki N, Someya T. Failure to find an association between myosin heavy chain 9, non-muscle (MYH9) and schizophrenia: a three-stage case-control association study. Schizophr Res, 2010; 118: 106-112.
    355. Aleksic B, Kushima I, Ito Y, Nakamura Y, Ujike H, Suzuki M, Inada T, Hashimoto R, Takeda M, Iwata N, Ozaki N. Genetic association study of KREMEN1 and DKK1 and schizophrenia in a Japanese population. Schizophr Res, 2010; 118: 113-117.
    356. Adachi Y, Aleksic B, Ozaki N. Comparison of pharmacological profiles of serotonin norepinephrine reuptake inhibitors. Clinical Neuropsychopharmacology and Therapeutics, 2010; 1: 10-15.
    357. Watanabe Y, Nunokawa A, Kaneko N, Muratake T, Arinami T, Ujike H, Inada T, Iwata N, Kunugi H, Itokawa M, Otowa T, Ozaki N, Someya T. Two-stage case-control association study of polymorphisms in rheumatoid arthritis susceptibility genes with schizophrenia. J Hum Genet, 2009; 54: 62-65.
    358. Watanabe Y, Nunokawa A, Kaneko N, Arinami T, Ujike H, Inada T, Iwata N, Kunugi H, Itokawa M, Otowa T, Ozaki N, Someya T. A two-stage case-control association study of PADI2 with schizophrenia. J Hum Genet, 2009; 54: 430-432.
    359. Ukai K, Shibayama H, Ishihara R, Ozaki N. Distribution of neurofibrillary tangles in diffuse neurofibrillary tangles with calcification. Psychiatry Clin Neurosci, 2009; 63: 646-651.
    360. Ujike H, Katsu T, Okahisa Y, Takaki M, Kodama M, Inada T, Uchimura N, Yamada M, Iwata N, Sora I, Iyo M, Ozaki N, Kuroda S. Genetic variants of D2 but not D3 or D4 dopamine receptor gene are associated with rapid onset and poor prognosis of methamphetamine psychosis. Prog Neuropsychopharmacol Biol Psychiatry, 2009; 33: 625-629.
    361. Ueno H, Nishigaki Y, Kong QP, Fuku N, Kojima S, Iwata N, Ozaki N, Tanaka M. Analysis of mitochondrial DNA variants in Japanese patients with schizophrenia. Mitochondrion, 2009; 9: 385-393.
    362. Tsunoka T, Kishi T, Ikeda M, Kitajima T, Yamanouchi Y, Kinoshita Y, Kawashima K, Okochi T, Okumura T, Inada T, Ozaki N, Iwata N. Association analysis of Group II metabotropic glutamate receptor genes (GRM2 and GRM3) with mood disorders and fluvoxamine response in a Japanese population. Prog Neuropsychopharmacol Biol Psychiatry, 2009; 33: 875-879.
    363. Takahashi T, Suzuki M, Tsunoda M, Maeno N, Kawasaki Y, Zhou SY, Hagino H, Niu L, Tsuneki H, Kobayashi S, Sasaoka T, Seto H, Kurachi M, Ozaki N. The Disrupted-in-Schizophrenia-1 Ser704Cys polymorphism and brain morphology in schizophrenia. Psychiatry Res, 2009; 172: 128-135.
    364. Suzuki M, Takahashi S, Matsushima E, Tsunoda M, Kurachi M, Okada T, Hayashi T, Ishii Y, Morita K, Maeda H, Katayama S, Kawahara R, Otsuka T, Hirayasu Y, Sekine M, Okubo Y, Motoshita M, Ohta K, Uchiyama M, Kojima T. Exploratory eye movement dysfunction as a discriminator for schizophrenia : a large sample study using a newly developed digital computerized system. Eur Arch Psychiatry Clin Neurosci, 2009; 259: 186-194.
    365. Shibata H, Tani A, Chikuhara T, Kikuta R, Sakai M, Ninomiya H, Tashiro N, Iwata N, Ozaki N, Fukumaki Y. Association study of polymorphisms in the group III metabotropic glutamate receptor genes, GRM4 and GRM7, with schizophrenia. Psychiatry Res, 2009; 167: 88-96.
    366. Okumura T, Okochi T, Kishi T, Ikeda M, Kitajima T, Yamanouchi Y, Kinoshita Y, Kawashima K, Tsunoka T, Ujike H, Inada T, Ozaki N, Iwata N. No association between polymorphisms of neuronal oxide synthase 1 gene (NOS1) and schizophrenia in a Japanese population. Neuromolecular Med, 2009; 11: 123-127.
    367. Okumura T, Kishi T, Okochi T, Ikeda M, Kitajima T, Yamanouchi Y, Kinoshita Y, Kawashima K, Tsunoka T, Inada T, Ozaki N, Iwata N. Genetic Association Analysis of Functional Polymorphisms in Neuronal Nitric Oxide Synthase 1 Gene (NOS1) and Mood Disorders and Fluvoxamine Response in Major Depressive Disorder in the Japanese Population. Neuropsychobiology, 2009; 61: 57-63.
    368. Okochi T, Kishi T, Ikeda M, Kitajima T, Kinoshita Y, Kawashima K, Okumura T, Tsunoka T, Inada T, Yamada M, Uchimura N, Iyo M, Sora I, Ozaki N, Ujike H, Iwata N. Genetic association analysis of NRG1 with methamphetamine-induced psychosis in a Japanese population. Prog Neuropsychopharmacol Biol Psychiatry, 2009; 33: 903-905.
    369. Okochi T, Ikeda M, Kishi T, Kawashima K, Kinoshita Y, Kitajima T, Yamanouchi Y, Tomita M, Inada T, Ozaki N, Iwata N. Meta-analysis of association between genetic variants in COMT and schizophrenia: an update. Schizophr Res, 2009; 110: 140-148.
    370. Okahisa Y, Ujike H, Kotaka T, Morita Y, Kodama M, Inada T, Yamada M, Iwata N, Iyo M, Sora I, Ozaki N, Kuroda S. Association between neuropeptide Y gene and its receptor Y1 gene and methamphetamine dependence. Psychiatry Clin Neurosci, 2009; 63: 417-422.
    371. Ohi K, Hashimoto R, Yasuda Y, Yoshida T, Takahashi H, Iike N, Fukumoto M, Takamura H, Iwase M, Kamino K, Ishii R, Kazui H, Sekiyama R, Kitamura Y, Azechi M, Ikezawa K, Kurimoto R, Kamagata E, Tanimukai H, Tagami S, Morihara T, Ogasawara M, Okochi M, Tokunaga H, Numata S, Ikeda M, Ohnuma T, Ueno S, Fukunaga T, Tanaka T, Kudo T, Arai H, Ohmori T, Iwata N, Ozaki N, Takeda M. Association study of the G72 gene with schizophrenia in a Japanese population: a multicenter study. Schizophr Res, 2009; 109: 80-85.
    372. Ohi K, Hashimoto R, Yasuda Y, Yamamori H, Hori H, Saitoh O, Tatsumi M, Takeda M, Iwata N, Ozaki N, Kamijima K, Kunugi H. No association between the Bcl2-interacting killer (BIK) gene and schizophrenia. Neurosci Lett, 2009; 463: 60-63.
    373. Nishiyama T, Ozaki N, Iwata N. Use of questionnaire infeasibility in order to detect cognitive disorders: example of the Center for Epidemiologic Studies Depression Scale in psychiatry settings. Psychiatry Clin Neurosci, 2009; 63: 23-29.
    374. Nishiyama T, Ozaki N, Iwata N. Practice-based depression screening for psychiatry outpatients: feasibility comparison of two-types of Center for Epidemiologic Studies Depression Scales. Psychiatry Clin Neurosci, 2009; 63: 632-638.
    375. Nakamura K, Sekine Y, Takei N, Iwata Y, Suzuki K, Anitha A, Inada T, Harano M, Komiyama T, Yamada M, Iwata N, Iyo M, Sora I, Ozaki N, Ujike H, Mori N. An association study of monoamine oxidase A (MAOA) gene polymorphism in methamphetamine psychosis. Neurosci Lett, 2009; 455: 120-123.
    376. Miura H, Shirokawa T, Isobe K, Ozaki N. Shifting the balance of brain tryptophan metabolism elicited by isolation housing and systemic administration of lipopolysaccharide in mice. Stress, 2009; 12: 206-214.
    377. Kubota K, Inoue K, Hashimoto R, Kumamoto N, Kosuga A, Tatsumi M, Kamijima K, Kunugi H, Iwata N, Ozaki N, Takeda M, Tohyama M. Tumor necrosis factor receptor-associated protein 1 regulates cell adhesion and synaptic morphology via modulation of N-cadherin expression. J Neurochem, 2009; 110: 496-508.
    378. Kotaka T, Ujike H, Okahisa Y, Takaki M, Nakata K, Kodama M, Inada T, Yamada M, Uchimura N, Iwata N, Sora I, Iyo M, Ozaki N, Kuroda S. G72 gene is associated with susceptibility to methamphetamine psychosis. Prog Neuropsychopharmacol Biol Psychiatry, 2009; 33: 1046-1049.
    379. Koga M, Ishiguro H, Yazaki S, Horiuchi Y, Arai M, Niizato K, Iritani S, Itokawa M, Inada T, Iwata N, Ozaki N, Ujike H, Kunugi H, Sasaki T, Takahashi M, Watanabe Y, Someya T, Kakita A, Takahashi H, Nawa H, Muchardt C, Yaniv M, Arinami T. Involvement of SMARCA2/BRM in the SWI/SNF chromatin-remodeling complex in schizophrenia. Hum Mol Genet, 2009; 18: 2483-2494.
    380. Kishi T, Tsunoka T, Ikeda M, Kawashima K, Okochi T, Kitajima T, Kinoshita Y, Okumura T, Yamanouchi Y, Inada T, Ozaki N, Iwata N. Serotonin 1A receptor gene and major depressive disorder: an association study and meta-analysis. J Hum Genet, 2009; 54: 629-633.
    381. Kishi T, Kitajima T, Tsunoka T, Okumura T, Ikeda M, Okochi T, Kinoshita Y, Kawashima K, Yamanouchi Y, Ozaki N, Iwata N. Possible association of prokineticin 2 receptor gene (PROKR2) with mood disorders in the Japanese population. Neuromolecular Med, 2009; 11: 114-122.
    382. Kishi T, Kitajima T, Tsunoka T, Ikeda M, Yamanouchi Y, Kinoshita Y, Kawashima K, Okochi T, Okumura T, Inada T, Ozaki N, Iwata N. Genetic association analysis of serotonin 2A receptor gene (HTR2A) with bipolar disorder and major depressive disorder in the Japanese population. Neurosci Res, 2009; 64: 231-234.
    383. Kishi T, Kitajima T, Ikeda M, Yamanouchi Y, Kinoshita Y, Kawashima K, Okochi T, Ozaki N, Iwata N. Orphan Nuclear Receptor Rev-erb Alpha Gene (NR1D1) and Fluvoxamine Response in Major Depressive Disorder in the Japanese Population. Neuropsychobiology, 2009; 59: 234-238.
    384. Kishi T, Kitajima T, Ikeda M, Yamanouchi Y, Kinoshita Y, Kawashima K, Okochi T, Okumura T, Tsunoka T, Ozaki N, Iwata N. CLOCK may predict the response to fluvoxamine treatment in Japanese major depressive disorder patients. Neuromolecular Med, 2009; 11: 53-57.
    385. Kishi T, Kitajima T, Ikeda M, Yamanouchi Y, Kinoshita Y, Kawashima K, Okochi T, Okumura T, Tsunoka T, Inada T, Ozaki N, Iwata N. Association study of clock gene (CLOCK) and schizophrenia and mood disorders in the Japanese population. Eur Arch Psychiatry Clin Neurosci, 2009; 259: 293-297.
    386. Kishi T, Ikeda M, Kitajima T, Yamanouchi Y, Kinoshita Y, Kawashima K, Okochi T, Tsunoka T, Okumura T, Inada T, Ujike H, Yamada M, Uchimura N, Sora I, Iyo M, Ozaki N, Iwata N. A functional polymorphism in estrogen receptor alpha gene is associated with Japanese methamphetamine induced psychosis. Prog Neuropsychopharmacol Biol Psychiatry, 2009; 33: 895-898.
    387. Kishi T, Ikeda M, Kitajima T, Yamanouchi Y, Kinoshita Y, Kawashima K, Okochi T, Okumura T, Tsunoka T, Inada T, Ozaki N, Iwata N. Association analysis of functional polymorphism in estrogen receptor alpha gene with schizophrenia and mood disorders in the Japanese population. Psychiatr Genet, 2009; 19: 217-218.
    388. Kawashima K, Ikeda M, Kishi T, Kitajima T, Yamanouchi Y, Kinoshita Y, Okochi T, Aleksic B, Tomita M, Okada T, Kunugi H, Inada T, Ozaki N, Iwata N. BDNF is not associated with schizophrenia: data from a Japanese population study and meta-analysis. Schizophr Res, 2009; 112: 72-79.
    389. Hattori E, Toyota T, Ishitsuka Y, Iwayama Y, Yamada K, Ujike H, Morita Y, Kodama M, Nakata K, Minabe Y, Nakamura K, Iwata Y, Takei N, Mori N, Naitoh H, Yamanouchi Y, Iwata N, Ozaki N, Kato T, Nishikawa T, Kashiwa A, Suzuki M, Shioe K, Shinohara M, Hirano M, Nanko S, Akahane A, Ueno M, Kaneko N, Watanabe Y, Someya T, Hashimoto K, Iyo M, Itokawa M, Arai M, Nankai M, Inada T, Yoshida S, Kunugi H, Nakamura M, Iijima Y, Okazaki Y, Higuchi T, Yoshikawa T. Preliminary genome-wide association study of bipolar disorder in the Japanese population. Am J Med Genet B Neuropsychiatr Genet, 2009; 150B: 1110-1117.
    390. Hakamata Y, Iwase M, Iwata H, Kobayashi T, Tamaki T, Nishio M, Matsuda H, Ozaki N, Inada T. Gender difference in relationship between anxiety-related personality traits and cerebral brain glucose metabolism. Psychiatry Res, 2009; 173: 206-211.
    391. Arai S, Shibata H, Sakai M, Ninomiya H, Iwata N, Ozaki N, Fukumaki Y. Association analysis of the glutamic acid decarboxylase 2 and the glutamine synthetase genes (GAD2, GLUL) with schizophrenia. Psychiatr Genet, 2009; 19: 6-13.
    392. Yoshimi A, Takahashi N, Saito S, Ito Y, Aleksic B, Usui H, Kawamura Y, Waki Y, Yoshikawa T, Kato T, Iwata N, Inada T, Noda Y, Ozaki N. Genetic analysis of the gene coding for DARPP-32 (PPP1R1B) in Japanese patients with schizophrenia or bipolar disorder. Schizophr Res, 2008; 100: 334-341.
    393. Yoshida K, Higuchi H, Takahashi H, Kamata M, Sato K, Inoue K, Suzuki T, Itoh K, Ozaki N. Influence of the tyrosine hydroxylase val81met polymorphism and catechol-O-methyltransferase val158met polymorphism on the antidepressant effect of milnacipran. Hum Psychopharmacol, 2008; 23: 121-128.
    394. Yamasaki N, Maekawa M, Kobayashi K, Kajii Y, Maeda J, Soma M, Takao K, Tanda K, Ohira K, Toyama K, Kanzaki K, Fukunaga K, Sudo Y, Ichinose H, Ikeda M, Iwata N, Ozaki N, Suzuki H, Higuchi M, Suhara T, Yuasa S, Miyakawa T. Alpha-CaMKII deficiency causes immature dentate gyrus, a novel candidate endophenotype of psychiatric disorders. Mol Brain, 2008; 1: 6.
    395. Uhl GR, Drgon T, Liu QR, Johnson C, Walther D, Komiyama T, Harano M, Sekine Y, Inada T, Ozaki N, Iyo M, Iwata N, Yamada M, Sora I, Chen CK, Liu HC, Ujike H, Lin SK. Genome-wide association for methamphetamine dependence: convergent results from 2 samples. Arch Gen Psychiatry, 2008; 65: 345-355.
    396. Tanaka M, Kobayashi D, Murakami Y, Ozaki N, Suzuki T, Iwata N, Haraguchi K, Ieiri I, Kinukawa N, Hosoi M, Ohtani H, Sawada Y, Mine K. Genetic polymorphisms in the 5-hydroxytryptamine type 3B receptor gene and paroxetine-induced nausea. Int J Neuropsychopharmacol, 2008; 11: 261-267.
    397. Takahashi T, Suzuki M, Tsunoda M, Kawamura Y, Takahashi N, Tsuneki H, Kawasaki Y, Zhou SY, Kobayashi S, Sasaoka T, Seto H, Kurachi M, Ozaki N. Association between the brain-derived neurotrophic factor Val66Met polymorphism and brain morphology in a Japanese sample of schizophrenia and healthy comparisons. Neurosci Lett, 2008; 435: 34-39.
    398. Takahashi T, Suzuki M, Tsunoda M, Kawamura Y, Takahashi N, Maeno N, Kawasaki Y, Zhou SY, Hagino H, Niu L, Tsuneki H, Kobayashi S, Sasaoka T, Seto H, Kurachi M, Ozaki N. The association of genotypic combination of the DRD3 and BDNF polymorphisms on the adhesio interthalamica and medial temporal lobe structures. Prog Neuropsychopharmacol Biol Psychiatry, 2008; 32: 1236-1242.
    399. Sukegawa M, Noda A, Soga T, Adachi Y, Tsuruta Y, Ozaki N, Koike Y. Comparison of sleep-disordered breathing and heart rate variability between hemodialysis and non-hemodialysis days in hemodialysis patients. Nagoya J Med Sci, 2008; 70: 83-88.
    400. Saito S, Takahashi N, Maeno N, Ito Y, Aleksic B, Usui H, Iidaka T, Inada T, Ozaki N. An association study of tachykinin receptor 3 gene with schizophrenia in the Japanese population. Neuroreport, 2008; 19: 471-473.
    401. Otani K, Ujike H, Sakai A, Okahisa Y, Kotaka T, Inada T, Harano M, Komiyama T, Hori T, Yamada M, Sekine Y, Iwata N, Iyo M, Sora I, Ozaki N, Kuroda S. Reduced CYP2D6 activity is a negative risk factor for methamphetamine dependence. Neurosci Lett, 2008; 434: 88-92.
    402. Okada T, Sato W, Kubota Y, Usui K, Inoue Y, Murai T, Hayashi T, Toichi M. Involvement of medial temporal structures in reflexive attentional shift by gaze. Soc Cogn Affect Neurosci, 2008; 3: 80-88.
    403. Ohtsuki T, Koga M, Ishiguro H, Horiuchi Y, Arai M, Niizato K, Itokawa M, Inada T, Iwata N, Iritani S, Ozaki N, Kunugi H, Ujike H, Watanabe Y, Someya T, Arinami T. A polymorphism of the metabotropic glutamate receptor mGluR7 (GRM7) gene is associated with schizophrenia. Schizophr Res, 2008; 101: 9-16.
    404. Ohtsuki T, Horiuchi Y, Koga M, Ishiguro H, Inada T, Iwata N, Ozaki N, Ujike H, Watanabe Y, Someya T, Arinami T. Association of polymorphisms in the haplotype block spanning the alternatively spliced exons of the NTNG1 gene at 1p13.3 with schizophrenia in Japanese populations. Neurosci Lett, 2008; 435: 194-197.
    405. Nunokawa A, Watanabe Y, Kitamura H, Kaneko N, Arinami T, Ujike H, Inada T, Iwata N, Kunugi H, Itokawa M, Ozaki N, Someya T. Large-scale case-control study of a functional polymorphism in the glutamate receptor, metabotropic 3 gene in patients with schizophrenia. Psychiatry Clin Neurosci, 2008; 62: 239-240.
    406. Niwa M, Nitta A, Cen X, Kitaichi K, Ozaki N, Yamada K, Nabeshima T. A novel molecule 'shati' increases dopamine uptake via the induction of tumor necrosis factor-alpha in pheochromocytoma-12 cells. J Neurochem, 2008; 107: 1697-1708.
    407. Morita Y, Ujike H, Tanaka Y, Kishimoto M, Okahisa Y, Kotaka T, Harano M, Inada T, Komiyama T, Hori T, Yamada M, Sekine Y, Iwata N, Iyo M, Sora I, Ozaki N, Kuroda S. The glycine transporter 1 gene (GLYT1) is associated with methamphetamine-use disorder. Am J Med Genet B Neuropsychiatr Genet, 2008; 147: 54-58.
    408. Miura H, Ozaki N, Shirokawa T, Isobe K. Changes in brain tryptophan metabolism elicited by ageing, social environment, and psychological stress in mice. Stress, 2008; 11: 160-169.
    409. Miura H, Ozaki N, Sawada M, Isobe K, Ohta T, Nagatsu T. A link between stress and depression: shifts in the balance between the kynurenine and serotonin pathways of tryptophan metabolism and the etiology and pathophysiology of depression. Stress, 2008; 11: 198-209.
    410. Masui T, Hashimoto R, Kusumi I, Suzuki K, Tanaka T, Nakagawa S, Suzuki T, Iwata N, Ozaki N, Kato T, Takeda M, Kunugi H, Koyama T. A possible association between missense polymorphism of the breakpoint cluster region gene and lithium prophylaxis in bipolar disorder. Prog Neuropsychopharmacol Biol Psychiatry, 2008; 32: 204-208.
    411. Kuratomi G, Iwamoto K, Bundo M, Kusumi I, Kato N, Iwata N, Ozaki N, Kato T. Aberrant DNA methylation associated with bipolar disorder identified from discordant monozygotic twins. Mol Psychiatry, 2008; 13: 429-441.
    412. Kotaka T, Ujike H, Morita Y, Kishimoto M, Okahisa Y, Inada T, Harano M, Komiyama T, Hori T, Yamada M, Sekine Y, Iwata N, Iyo M, Sora I, Ozaki N, Kuroda S. Association study between casein kinase 1 epsilon gene and methamphetamine dependence. Ann N Y Acad Sci, 2008; 1139: 43-48.
    413. Kishimoto M, Ujike H, Okahisa Y, Kotaka T, Takaki M, Kodama M, Inada T, Yamada M, Uchimura N, Iwata N, Sora I, Iyo M, Ozaki N, Kuroda S. The Frizzled 3 gene is associated with methamphetamine psychosis in the Japanese population. Behav Brain Funct, 2008; 4: 37.
    414. Kishimoto M, Ujike H, Motohashi Y, Tanaka Y, Okahisa Y, Kotaka T, Harano M, Inada T, Yamada M, Komiyama T, Hori T, Sekine Y, Iwata N, Sora I, Iyo M, Ozaki N, Kuroda S. The Dysbindin Gene (DTNBP1) Is Associated with Methamphetamine Psychosis. Biol Psychiatry, 2008; 63: 191-196.
    415. Kishi T, Kitajima T, Ikeda M, Yamanouchi Y, Kinoshita Y, Kawashima K, Okochi T, Ozaki N, Iwata N. Association analysis of nuclear receptor Rev-erb alpha gene (NR1D1) with mood disorders in the Japanese population. Neurosci Res, 2008; 62: 211-215.
    416. Kishi T, Ikeda M, Kitajima T, Yamanouchi Y, Kinoshita Y, Kawashima K, Okochi T, Inada T, Ozaki N, Iwata N. Genetic association analysis of tagging SNPs in alpha4 and beta2 subunits of neuronal nicotinic acetylcholine receptor genes (CHRNA4 and CHRNB2) with schizophrenia in the Japanese population. J Neural Transm, 2008; 115: 1457-1461.
    417. Kishi T, Ikeda M, Kitajima T, Yamanouchi Y, Kinoshita Y, Kawashima K, Inada T, Harano M, Komiyama T, Hori T, Yamada M, Iyo M, Sora I, Sekine Y, Ozaki N, Ujike H, Iwata N. Prostate apoptosis response 4 gene is not associated with methamphetamine-use disorder in the Japanese population. Ann N Y Acad Sci, 2008; 1139: 83-88.
    418. Kishi T, Ikeda M, Kitajima T, Yamanouchi Y, Kinoshita Y, Kawashima K, Inada T, Harano M, Komiyama T, Hori T, Yamada M, Iyo M, Sora I, Sekine Y, Ozaki N, Ujike H, Iwata N. Alpha4 and beta2 subunits of neuronal nicotinic acetylcholine receptor genes are not associated with methamphetamine-use disorder in the Japanese population. Ann N Y Acad Sci, 2008; 1139: 70-82.
    419. Kishi T, Ikeda M, Kitajima T, Yamanouchi Y, Kinoshita Y, Kawashima K, Inada T, Harano M, Komiyama T, Hori T, Yamada M, Iyo M, Sora I, Sekine Y, Ozaki N, Ujike H, Iwata N. Glutamate cysteine ligase modifier (GCLM) subunit gene is not associated with methamphetamine-use disorder or schizophrenia in the Japanese population. Ann N Y Acad Sci, 2008; 1139: 63-69.
    420. Kishi T, Ikeda M, Kitajima T, Suzuki T, Yamanouchi Y, Kinoshita Y, Kawashima K, Ozaki N, Iwata N. No association between prostate apoptosis response 4 gene (PAWR) in schizophrenia and mood disorders in a Japanese population. Am J Med Genet B Neuropsychiatr Genet, 2008; 147B: 531-534.
    421. Kinoshita Y, Ikeda M, Ujike H, Kitajima T, Yamanouchi Y, Aleksic B, Kishi T, Kawashima K, Ohkouchi T, Ozaki N, Inada T, Harano M, Komiyama T, Hori T, Yamada M, Sekine Y, Iyo M, Sora I, Iwata N. Association study of the calcineurin A gamma subunit gene (PPP3CC) and methamphetamine-use disorder in a Japanese population. Ann N Y Acad Sci, 2008; 1139: 57-62.
    422. Kawashima K, Kishi T, Ikeda M, Kitajima T, Yamanouchi Y, Kinoshita Y, Takahashi N, Saito S, Ohi K, Yasuda Y, Hashimoto R, Takeda M, Inada T, Ozaki N, Iwata N. No association between tagging SNPs of SNARE complex genes (STX1A, VAMP2 and SNAP25) and schizophrenia in a Japanese population. Am J Med Genet B Neuropsychiatr Genet, 2008; 147B: 1327-1331.
    423. Kanahara N, Miyatake R, Sekine Y, Inada T, Ozaki N, Iwata N, Harano M, Komiyama T, Yamada M, Sora I, Ujike H, Iyo M, Hashimoto K. Association study between the PIK4CA gene and methamphetamine use disorder in a Japanese population. Am J Med Genet B Neuropsychiatr Genet, 2008; 150B: 233-238.
    424. Kakiuchi C, Ishiwata M, Nanko S, Ozaki N, Iwata N, Umekage T, Tochigi M, Kohda K, Sasaki T, Imamura A, Okazaki Y, Kato T. Up-regulation of ADM and SEPX1 in the lymphoblastoid cells of patients in monozygotic twins discordant for schizophrenia. Am J Med Genet B Neuropsychiatr Genet, 2008; 147B: 557-564.
    425. Ji X, Takahashi N, Saito S, Ishihara R, Maeno N, Inada T, Ozaki N. Relationship between three serotonin receptor subtypes (HTR3A, HTR2A and HTR4) and treatment-resistant schizophrenia in the Japanese population. Neurosci Lett, 2008; 435: 95-98.
    426. Ji X, Takahashi N, Branko A, Ishihara R, Nagai T, Mouri A, Saito S, Maeno N, Inada T, Ozaki N. An association between serotonin receptor 3B gene (HTR3B) and treatment-resistant schizophrenia (TRS) in a Japanese population. Nagoya J Med Sci, 2008; 70: 11-17.
    427. Iwamoto K, Takahashi M, Nakamura Y, Kawamura Y, Ishihara R, Uchiyama Y, Ebe K, Noda A, Noda Y, Yoshida K, Iidaka T, Ozaki N. The effects of acute treatment with paroxetine, amitriptyline, and placebo on driving performance and cognitive function in healthy Japanese subjects: a double-blind crossover trial. Hum Psychopharmacol, 2008; 23: 399-407.
    428. Iwamoto K, Kawamura Y, Takahashi M, Uchiyama Y, Ebe K, Yoshida K, Iidaka T, Noda Y, Ozaki N. Plasma amitriptyline level after acute administration, and driving performance in healthy volunteers. Psychiatry Clin Neurosci, 2008; 62: 610-616.
    429. Ito Y, Yamada S, Takahashi N, Saito S, Yoshimi A, Inada T, Noda Y, Ozaki N. No association between the protein tyrosine phosphatase, receptor-type, Z Polypeptide 1 (PTPRZ1) gene and schizophrenia in the Japanese population. Am J Med Genet B Neuropsychiatr Genet, 2008; 147B: 1013-1018.
    430. Ito Y, Nakamura Y, Takahashi N, Saito S, Aleksic B, Iwata N, Inada T, Ozaki N. A genetic association study of the FXYD domain containing ion transport regulator 6 (FXYD6) gene, encoding phosphohippolin, in susceptibility to schizophrenia in a Japanese population. Neurosci Lett, 2008; 438: 70-75.
    431. Ishiguro H, Imai K, Koga M, Horiuchi Y, Inada T, Iwata N, Ozaki N, Ujike H, Itokawa M, Kunugi H, Sasaki T, Watanabe Y, Someya T, Arinami T. Replication study for associations between polymorphisms in the CLDN5 and DGCR2 genes in the 22q11 deletion syndrome region and schizophrenia. Psychiatr Genet, 2008; 18: 255-256.
    432. Inada T, Koga M, Ishiguro H, Horiuchi Y, Syu A, Yoshio T, Takahashi N, Ozaki N, Arinami T. Pathway-based association analysis of genome-wide screening data suggest that genes associated with the gamma-aminobutyric acid receptor signaling pathway are involved in neuroleptic-induced, treatment-resistant tardive dyskinesia. Pharmacogenet Genomics, 2008; 18: 317-323.
    433. Ikeda M, Yamanouchi Y, Kinoshita Y, Kitajima T, Yoshimura R, Hashimoto S, O'Donovan MC, Nakamura J, Ozaki N, Iwata N. Variants of dopamine and serotonin candidate genes as predictors of response to risperidone treatment in first-episode schizophrenia. Pharmacogenomics, 2008; 9: 1437-1443.
    434. Ikeda M, Takahashi N, Saito S, Aleksic B, Watanabe Y, Nunokawa A, Yamanouchi Y, Kitajima T, Kinoshita Y, Kishi T, Kawashima K, Hashimoto R, Ujike H, Inada T, Someya T, Takeda M, Ozaki N, Iwata N. Failure to replicate the association between NRG1 and schizophrenia using Japanese large sample. Schizophr Res, 2008; 101: 1-8.
    435. Ikeda M, Hikita T, Taya S, Uraguchi-Asaki J, Toyo-oka K, Wynshaw-Boris A, Ujike H, Inada T, Takao K, Miyakawa T, Ozaki N, Kaibuchi K, Iwata N. Identification of YWHAE, a gene encoding 14-3-3epsilon, as a possible susceptibility gene for schizophrenia. Hum Mol Genet, 2008; 17: 3212-3222.
    436. Hashimoto T, Hashimoto K, Miyatake R, Matsuzawa D, Sekine Y, Inada T, Ozaki N, Iwata N, Harano M, Komiyama T, Yamada M, Sora I, Ujike H, Iyo M. Association study between polymorphisms in glutathione-related genes and methamphetamine use disorder in a Japanese population. Am J Med Genet B Neuropsychiatr Genet, 2008; 147B: 1040-1046.
    437. Deng X, Sagata N, Takeuchi N, Tanaka M, Ninomiya H, Iwata N, Ozaki N, Shibata H, Fukumaki Y. Association study of polymorphisms in the neutral amino acid transporter genes SLC1A4, SLC1A5 and the glycine transporter genes SLC6A5, SLC6A9 with schizophrenia. BMC Psychiatry, 2008; 8: 58.
    438. Aleksic B, Ikeda M, Ishihara R, Saito S, Inada T, Iwata N, Ozaki N. No association between the oligodendrocyte-related gene PLP1 and schizophrenia in the Japanese population. J Hum Genet, 2008; 53: 863-866.
    439. Albalushi T, Horiuchi Y, Ishiguro H, Koga M, Inada T, Iwata N, Ozaki N, Ujike H, Watanabe Y, Someya T, Arinami T. Replication study and meta-analysis of the genetic association of GRM3 gene polymorphisms with schizophrenia in a large Japanese case-control population. Am J Med Genet B Neuropsychiatr Genet, 2008; 147: 392-396.
    440. Yoshida K, Higuchi H, Ozaki N. Successful treatment of severe antidepressant-induced nausea with a combination of milnacipran and olanzapine. Pharmacopsychiatry, 2007; 40: 84-85.
    441. Yoshida K, Higuchi H, Kamata M, Takahashi H, Inoue K, Suzuki T, Itoh K, Ozaki N. The G196A polymorphism of the brain-derived neurotrophic factor gene and the antidepressant effect of milnacipran and fluvoxamine. J Psychopharmacol, 2007; 21: 650-656.
    442. Urata T, Takahashi N, Hakamata Y, Iijima Y, Kuwahara N, Ozaki N, Ono Y, Amano M, Inada T. Gene-gene interaction analysis of personality traits in a Japanese population using an electrochemical DNA array chip analysis. Neurosci Lett, 2007; 414: 209-212.
    443. Tomita Y, Ikeda M, Mutoh H, Inada T, Iwata N, Ozaki N, Honda H. Association study between Apolipoprotein L and schizophrenia by exhaustive and rule-based combination analysis for identification of multilocus interactions. J Biosci Bioeng, 2007; 103: 303-310.
    444. Tabuse H, Kalali A, Azuma H, Ozaki N, Iwata N, Naitoh H, Higuchi T, Kanba S, Shioe K, Akechi T, Furukawa TA. The new GRID Hamilton Rating Scale for Depression demonstrates excellent inter-rater reliability for inexperienced and experienced raters before and after training. Psychiatry Res, 2007; 153: 61-67.
    445. Sato W, Okada T, Toichi M. Attentional shift by gaze is triggered without awareness. Exp Brain Res, 2007; 183: 87-94.
    446. Saito S, Takahashi N, Ishihara R, Ikeda M, Suzuki T, Kitajima T, Yamanouchi Y, Iwata N, Yamada M, Yoshida K, Inada T, Ozaki N. Association Study between Vesicle-Associated Membrane Protein 2 Gene Polymorphisms and Fluvoxamine Response in Japanese Major Depressive Patients. Neuropsychobiology, 2007; 54: 226-230.
    447. Ohnishi T, Yamada K, Ohba H, Iwayama Y, Toyota T, Hattori E, Inada T, Kunugi H, Tatsumi M, Ozaki N, Iwata N, Sakamoto K, Iijima Y, Iwata Y, Tsuchiya KJ, Sugihara G, Nanko S, Osumi N, Detera-Wadleigh SD, Kato T, Yoshikawa T. A Promoter Haplotype of the Inositol Monophosphatase 2 Gene (IMPA2) at 18p11.2 Confers a Possible Risk for Bipolar Disorder by Enhancing Transcription. Neuropsychopharmacology, 2007; 32: 1727-1737.
    448. Nakayama H, Kitaichi K, Ito Y, Hashimoto K, Takagi K, Yokoi T, Ozaki N, Yamamoto T, Hasegawa T. The role of organic cation transporter-3 in methamphetamine disposition and its behavioral response in rats. Brain Res, 2007; 1184: 260-269.
    449. Mouri A, Noda Y, Noda A, Nakamura T, Tokura T, Yura Y, Nitta A, Furukawa H, Nabeshima T. Involvement of a dysfunctional dopamine-D1/N-methyl-d-aspartate-NR1 and Ca2+/calmodulin-dependent protein kinase II pathway in the impairment of latent learning in a model of schizophrenia induced by phencyclidine. Mol Pharmacol, 2007; 71: 1598-1609.
    450. Miura H, Kitagami T, Ozaki N. Suppressive effect of paroxetine, a selective serotonin uptake inhibitor, on tetrahydrobiopterin levels and dopamine as well as serotonin turnover in the mesoprefrontal system of mice. Synapse, 2007; 61: 698-706.
    451. Matsuzawa D, Hashimoto K, Miyatake R, Shirayama Y, Shimizu E, Maeda K, Suzuki Y, Mashimo Y, Sekine Y, Inada T, Ozaki N, Iwata N, Harano M, Komiyama T, Yamada M, Sora I, Ujike H, Hata A, Sawa A, Iyo M. Identification of Functional Polymorphisms in the Promoter Region of the Human PICK1 Gene and Their Association With Methamphetamine Psychosis. Am J Psychiatry, 2007; 164: 1105-1114.
    452. Maeno N, Takahashi N, Saito S, Ji X, Ishihara R, Aoyama N, Branko A, Miura H, Ikeda M, Suzuki T, Kitajima T, Yamanouchi Y, Kinoshita Y, Iwata N, Inada T, Ozaki N. Association of SOX10 with schizophrenia in the Japanese population. Psychiatr Genet, 2007; 17: 227-231.
    453. Maeno N, Takahashi N, Saito S, Ji X, Branko A, Ishihara R, Yoshida K, Inada T, Iidaka T, Ozaki N. Association study between the transferrin gene and schizophrenia in the Japanese population. Neuroreport, 2007; 18: 517-520.
    454. Koga M, Ishiguro H, Horiuchi Y, Albalushi T, Inada T, Iwata N, Ozaki N, Ujike H, Muratake T, Someya T, Arinami T. Failure to confirm the association between the FEZ1 gene and schizophrenia in a Japanese population. Neurosci Lett, 2007; 417: 326-329.
    455. Kimura H, Tonoike T, Muroya T, Yoshida K, Ozaki N. Age of onset has limited association with body mass index at time of presentation for anorexia nervosa: Comparison of peak-onset and late-onset anorexia nervosa groups. Psychiatry Clin Neurosci, 2007; 61: 646-650.
    456. Ito M, Yoshida K, Kimura H, Ozaki N, Kurita K. Successful Treatment of Trigeminal Neuralgia With Milnacipran. Clin Neuropharmacol, 2007; 30: 183-185.
    457. Ishiguro H, Koga M, Horiuchi Y, Inada T, Iwata N, Ozaki N, Ujike H, Muratake T, Someya T, Arinami T. PICK1 is not a susceptibility gene for schizophrenia in a Japanese population: Association study in a large case-control population. Neurosci Res, 2007; 58: 145-148.
    458. Ishiguro H, Horiuchi Y, Koga M, Inada T, Iwata N, Ozaki N, Ujike H, Muratake T, Someya T, Arinami T. RGS4 is not a susceptibility gene for schizophrenia in Japanese: association study in a large case-control population. Schizophr Res, 2007; 89: 161-164.
    459. Ikeda M, Ozaki N, Yamanouchi Y, Suzuki T, Kitajima T, Kinoshita Y, Inada T, Iwata N. No association between the glutamate decarboxylase 67 gene (GAD1) and schizophrenia in the Japanese population. Schizophr Res, 2007; 91: 22-26.
    460. Ikeda M, Ozaki N, Suzuki T, Kitajima T, Yamanouchi Y, Kinoshita Y, Kishi T, Sekine Y, Iyo M, Harano M, Komiyama T, Yamada M, Sora I, Ujike H, Inada T, Iwata N. Possible association of beta-arrestin 2 gene with methamphetamine use disorder, but not schizophrenia. Genes Brain Behav, 2007; 6: 107-112.
    461. Horiuchi Y, Ishiguro H, Koga M, Inada T, Iwata N, Ozaki N, Ujike H, Muratake T, Someya T, Arinami T. Support for association of the PPP3CC gene with schizophrenia. Mol Psychiatry, 2007; 12: 891-893.
    462. Hashimoto R, Hashimoto H, Shintani N, Chiba S, Hattori S, Okada T, Nakajima M, Tanaka K, Kawagishi N, Nemoto K, Mori T, Ohnishi T, Noguchi H, Hori H, Suzuki T, Iwata N, Ozaki N, Nakabayashi T, Saitoh O, Kosuga A, Tatsumi M, Kamijima K, Weinberger DR, Kunugi H, Baba A. Pituitary adenylate cyclase-activating polypeptide is associated with schizophrenia. Mol Psychiatry, 2007; 12: 1026-1032.
    463. Deng X, Shibata H, Takeuchi N, Rachi S, Sakai M, Ninomiya H, Iwata N, Ozaki N, Fukumaki Y. Association study of polymorphisms in the glutamate transporter genes SLC1A1, SLC1A3, and SLC1A6 with schizophrenia. Am J Med Genet B Neuropsychiatr Genet, 2007; 144: 271-278.
    464. Aleksic B, Ishihara R, Takahashi N, Maeno N, Ji X, Saito S, Inada T, Ozaki N. Gap junction coding genes and schizophrenia: a genetic association study. J Hum Genet, 2007; 52: 498-501.
    465. Usui H, Takahashi N, Saito S, Ishihara R, Aoyama N, Ikeda M, Suzuki T, Kitajima T, Yamanouchi Y, Kinoshita Y, Yoshida K, Iwata N, Inada T, Ozaki N. The 2',3'-cyclic nucleotide 3'-phosphodiesterase and oligodendrocyte lineage transcription factor 2 genes do not appear to be associated with schizophrenia in the Japanese population. Schizophr Res, 2006; 88: 245-250.
    466. Ujike H, Sakai A, Nakata K, Tanaka Y, Kodaka T, Okahisa Y, Harano M, Inada T, Yamada M, Komiyama T, Hori T, Sekine Y, Iwata N, Sora I, Iyo M, Ozaki N, Kuroda S. Association Study of the Dihydropyrimidinase-Related Protein 2 Gene and Methamphetamine Psychosis. Ann N Y Acad Sci, 2006; 1074: 90-96.
    467. Takahashi N, Ishihara R, Saito S, Maemo N, Aoyama N, Ji X, Miura H, Ikeda M, Iwata N, Suzuki T, Kitajima T, Yamanouchi Y, Kinoshita Y, Ozaki N, Inada T. Association between chromogranin A gene polymorphism and schizophrenia in the Japanese population. Schizophr Res, 2006; 83: 179-183.
    468. Suzuki A, Nakamura K, Sekine Y, Minabe Y, Takei N, Suzuki K, Iwata Y, Kawai M, Takebayashi K, Matsuzaki H, Iyo M, Ozaki N, Inada T, Iwata N, Harano M, Komiyama T, Yamada M, Sora I, Ujike H, Mori N. An association study between catechol-O-methyl transferase gene polymorphism and methamphetamine psychotic disorder. Psychiatr Genet, 2006; 16: 133-138.
    469. Shibata H, Aramaki T, Sakai M, Ninomiya H, Tashiro N, Iwata N, Ozaki N, Fukumaki Y. Association study of polymorphisms in the GluR7, KA1 and KA2 kainate receptor genes (GRIK3, GRIK4, GRIK5) with schizophrenia. Psychiatry Res, 2006; 141: 39-51.
    470. Okada T, Sato W, Toichi M. Right hemispheric dominance in gaze-triggered reflexive shift of attention in humans. Brain Cogn, 2006; 62: 128-133.
    471. Nomura A, Ujike H, Tanaka Y, Otani K, Morita Y, Kishimoto M, Morio A, Harano M, Inada T, Yamada M, Komiyama T, Sekine Y, Iwata N, Sora I, Iyo M, Ozaki N, Kuroda S. Genetic variant of prodynorphin gene is risk factor for methamphetamine dependence. Neurosci Lett, 2006; 400: 158-162.
    472. Nomura A, Ujike H, Tanaka Y, Kishimoto M, Otani K, Morita Y, Morio A, Harano M, Inada T, Yamada M, Komiyama T, Hori T, Sekine Y, Iwata N, Sora I, Iyo M, Ozaki N, Kuroda S. Association Study of the Tumor Necrosis Factor-{alpha} Gene and Its 1A Receptor Gene with Methamphetamine Dependence. Ann N Y Acad Sci, 2006; 1074: 116-124.
    473. Noda A, Nakai S, Soga T, Sugiura T, Iwayama N, Maeda K, Atarashi M, Yasuma F, Ozaki N, Yokota M, Koike Y. Factors contributing to sleep disturbance and hypnotic drug use in hemodialysis patients. Intern Med, 2006; 45: 1273-1278.
    474. Nakamura K, Chen CK, Sekine Y, Iwata Y, Anitha A, Loh el W, Takei N, Suzuki A, Kawai M, Takebayashi K, Suzuki K, Minabe Y, Tsuchiya K, Yamada K, Iyo M, Ozaki N, Inada T, Iwata N, Harano M, Komiyama T, Yamada M, Sora I, Ujike H, Ball DM, Yoshikawa T, Lin SK, Mori N. Association analysis of SOD2 variants with methamphetamine psychosis in Japanese and Taiwanese populations. Hum Genet, 2006; 120: 243-252.
    475. Nakajima A, Kamitsuji S, Saito A, Tanaka E, Nishimura K, Horikawa N, Ozaki N, Tomatsu T, Hara M, Kamatani N, Yamanaka H. Disability and patient's appraisal of general health contribute to depressed mood in rheumatoid arthritis in a large clinical study in Japan. Mod Rheumatol, 2006; 16: 151-157.
    476. Morio A, Ujike H, Nomura A, Tanaka Y, Morita Y, Otani K, Kishimoto M, Harano M, Inada T, Komiyama T, Yamada M, Sekine Y, Iwata N, Iyo M, Sora I, Ozaki N, Kuroda S. No Association between CART (Cocaine- and Amphetamine-Regulated Transcript) Gene and Methamphetamine Dependence. Ann N Y Acad Sci, 2006; 1074: 411-417.
    477. Masui T, Hashimoto R, Kusumi I, Suzuki K, Tanaka T, Nakagawa S, Suzuki T, Iwata N, Ozaki N, Kato T, Kunugi H, Koyama T. Lithium response and Val66Met polymorphism of the brain-derived neurotrophic factor gene in Japanese patients with bipolar disorder. Psychiatr Genet, 2006; 16: 49-50.
    478. Kobayashi H, Hata H, Ujike H, Harano M, Inada T, Komiyama T, Yamada M, Sekine Y, Iwata N, Iyo M, Ozaki N, Itokawa M, Naka M, Ide S, Ikeda K, Numachi Y, Sora I. Association analysis of delta-opioid receptor gene polymorphisms in methamphetamine dependence/psychosis. Am J Med Genet B Neuropsychiatr Genet, 2006; 141: 482-486.
    479. Kishi T, Ikeda M, Suzuki T, Kitajima T, Yamanouchi Y, Kinoshita Y, Ozaki N, Iwata N. No association of complexin1 and complexin2 genes with schizophrenia in a Japanese population. Schizophr Res, 2006; 82: 185-189.
    480. Kimura H, Ozaki N. Diagnosis and treatment of depression in dialysis patients. Ther Apher Dial, 2006; 10: 328-332.
    481. Ikeda M, Iwata N, Suzuki T, Kitajima T, Yamanouchi Y, Kinoshiya Y, Sekine Y, Iyo M, Harano M, Komiyama T, Yamada M, Sora I, Ujike H, Inada T, Ozaki N. Positive association of AKT1 haplotype to Japanese methamphetamine use disorder. Int J Neuropsychopharmacol, 2006; 9: 77-81.
    482. Ikeda M, Iwata N, Suzuki T, Kitajima T, Yamanouchi Y, Kinoshita Y, Ozaki N. No association of serotonin transporter gene (SLC6A4) with schizophrenia and bipolar disorder in Japanese patients: association analysis based on linkage disequilibrium. J Neural Transm, 2006; 113: 899-905.
    483. Ikeda M, Iwata N, Kitajima T, Suzuki T, Yamanouchi Y, Kinoshita Y, Ozaki N. Positive association of the serotonin 5-HT7 receptor gene with schizophrenia in a Japanese population. Neuropsychopharmacology, 2006; 31: 866-871.
    484. Iidaka T, Matsumoto A, Ozaki N, Suzuki T, Iwata N, Yamamoto Y, Okada T, Sadato N. Volume of left amygdala subregion predicted temperamental trait of harm avoidance in female young subjects. A voxel-based morphometry study. Brain Res, 2006; 1125: 85-93.
    485. Ide S, Kobayashi H, Ujike H, Ozaki N, Sekine Y, Inada T, Harano M, Komiyama T, Yamada M, Iyo M, Iwata N, Tanaka K, Shen H, Iwahashi K, Itokawa M, Minami M, Satoh M, Ikeda K, Sora I. Linkage disequilibrium and association with methamphetamine dependence/psychosis of mu-opioid receptor gene polymorphisms. Pharmacogenomics J, 2006; 6: 179-188.
    486. Hashimoto R, Numakawa T, Ohnishi T, Kumamaru E, Yagasaki Y, Ishimoto T, Mori T, Nemoto K, Adachi N, Izumi A, Chiba S, Noguchi H, Suzuki T, Iwata N, Ozaki N, Taguchi T, Kamiya A, Kosuga A, Tatsumi M, Kamijima K, Weinberger DR, Sawa A, Kunugi H. Impact of the DISC1 Ser704Cys polymorphism on risk for major depression, brain morphology and ERK signaling. Hum Mol Genet, 2006; 15: 3024-3033.
    487. Hakamata Y, Iwase M, Iwata H, Kobayashi T, Tamaki T, Nishio M, Kawahara K, Matsuda H, Ozaki N, Honjo S, Inada T. Regional brain cerebral glucose metabolism and temperament: a positron emission tomography study. Neurosci Lett, 2006; 396: 33-37.
    488. Aoyama N, Takahashi N, Saito S, Maeno N, Ishihara R, Ji X, Miura H, Ikeda M, Suzuki T, Kitajima T, Yamanouchi Y, Kinoshita Y, Yoshida K, Iwata N, Inada T, Ozaki N. Association study between kynurenine 3-monooxygenase gene and schizophrenia in the Japanese population. Genes Brain Behav, 2006; 5: 364-368.
    489. Aoyama N, Takahashi N, Kitaichi K, Ishihara R, Saito S, Maeno N, Ji X, Takagi K, Sekine Y, Iyo M, Harano M, Komiyama T, Yamada M, Sora I, Ujike H, Iwata N, Inada T, Ozaki N. Association between gene polymorphisms of SLC22A3 and methamphetamine use disorder. Alcohol Clin Exp Res, 2006; 30: 1644-1649.
    490. Ando T, Komaki G, Naruo T, Okabe K, Takii M, Kawai K, Konjiki F, Takei M, Oka T, Takeuchi K, Masuda A, Ozaki N, Suematsu H, Denda K, Kurokawa N, Itakura K, Yamaguchi C, Kono M, Suzuki T, Nakai Y, Nishizono-Maher A, Koide M, Murakami K, Nagamine K, Tomita Y, Ookuma K, Tomita K, Tonai E, Ooshima A, Ishikawa T, Ichimaru Y. Possible role of preproghrelin gene polymorphisms in susceptibility to bulimia nervosa. Am J Med Genet B Neuropsychiatr Genet, 2006; 141: 929-934.
    491. Saito S, Ikeda M, Iwata N, Suzuki T, Kitajima T, Yamanouchi Y, Kinoshita Y, Takahashi N, Inada T, Ozaki N. No association was found between a functional SNP in ZDHHC8 and schizophrenia in a Japanese case-control population. Neurosci Lett, 2005; 374: 21-24.
    492. Ohgake S, Hashimoto K, Shimizu E, Koizumi H, Okamura N, Koike K, Matsuzawa D, Sekine Y, Inada T, Ozaki N, Iwata N, Harano M, Komiyama T, Yamada M, Sora I, Ujike H, Shirayama Y, Iyo M. Functional polymorphism of the NQO2 gene is associated with methamphetamine psychosis. Addict Biol, 2005; 10: 145-148.
    493. Nishiyama T, Ikeda M, Iwata N, Suzuki T, Kitajima T, Yamanouchi Y, Sekine Y, Iyo M, Harano M, Komiyama T, Yamada M, Sora I, Ujike H, Inada T, Furukawa T, Ozaki N. Haplotype association between GABAA receptor gamma2 subunit gene (GABRG2) and methamphetamine use disorder. Pharmacogenomics J, 2005; 5: 89-95.
    494. Morita Y, Ujike H, Tanaka Y, Uchida N, Nomura A, Otani K, Kishimoto M, Morio A, Inada T, Harano M, Komiyama T, Yamada M, Sekine Y, Iwata N, Iyo M, Sora I, Ozaki N. The X-box binding protein 1 (XBP1) gene is not associated with methamphetamine dependence. Neurosci Lett, 2005; 383: 194-198.
    495. Morita Y, Ujike H, Tanaka Y, Uchida N, Nomura A, Ohtani K, Kishimoto M, Morio A, Imamura T, Sakai A, Inada T, Harano M, Komiyama T, Yamada M, Sekine Y, Iwata N, Iyo M, Sora I, Ozaki N, Kuroda S. A nonsynonymous polymorphism in the human fatty acid amide hydrolase gene did not associate with either methamphetamine dependence or schizophrenia. Neurosci Lett, 2005; 376: 182-187.
    496. Miura H, Qiao H, Kitagami T, Ohta T, Ozaki N. Fluvoxamine, a selective serotonin reuptake inhibitor, suppresses tetrahydrobiopterin levels and dopamine as well as serotonin turnover in the mesoprefrontal system of mice. Psychopharmacology (Berl), 2005; 177: 307-314.
    497. Miura H, Qiao H, Kitagami T, Ohta T, Ozaki N. Effects of fluvoxamine on levels of dopamine, serotonin, and their metabolites in the hippocampus elicited by isolation housing and novelty stress in adult rats. Int J Neurosci, 2005; 115: 367-378.
    498. Maeno N, Kusunoki K, Kitajima T, Iwata N, Ono Y, Hashimoto S, Imai M, Li L, Kayukawa Y, Ohta T, Ozaki N. Personality of seasonal affective disorder analyzed by Tri-dimensional Personality Questionnaire. J Affect Disord, 2005; 85: 267-273.
    499. Kinoshita Y, Suzuki T, Ikeda M, Kitajima T, Yamanouchi Y, Inada T, Yoneda H, Iwata N, Ozaki N. No association with the calcineurin A gamma subunit gene (PPP3CC) haplotype to Japanese schizophrenia. J Neural Transm, 2005; 112: 1255-1262.
    500. Ikeda M, Iwata N, Suzuki T, Kitajima T, Yamanouchi Y, Kinoshita Y, Ozaki N. No association of GSK3beta gene (GSK3B) with Japanese schizophrenia. Am J Med Genet B Neuropsychiatr Genet, 2005; 134: 90-92.
    501. Ikeda M, Iwata N, Suzuki T, Kitajima T, Yamanouchi Y, Kinoshita Y, Inada T, Ujike H, Ozaki N. Association Analysis of Chromosome 5 GABA(A) Receptor Cluster in Japanese Schizophrenia Patients. Biol Psychiatry, 2005; 58: 440-445.
    502. Ikeda M, Iwata N, Suzuki T, Kitajima T, Yamanouchi Y, Kinoshita Y, Inada T, Ozaki N. No association of haplotype-tagging SNPs in TRAR4 with schizophrenia in Japanese patients. Schizophr Res, 2005; 78: 127-130.
    503. Iidaka T, Ozaki N, Matsumoto A, Nogawa J, Kinoshita Y, Suzuki T, Iwata N, Yamamoto Y, Okada T, Sadato N. A variant C178T in the regulatory region of the serotonin receptor gene HTR3A modulates neural activation in the human amygdala. J Neurosci, 2005; 25: 6460-6466.
    504. Hashimoto T, Hashimoto K, Matsuzawa D, Shimizu E, Sekine Y, Inada T, Ozaki N, Iwata N, Harano M, Komiyama T, Yamada M, Sora I, Ujike H, Iyo M. A functional glutathione S-transferase P1 gene polymorphism is associated with methamphetamine-induced psychosis in Japanese population. Am J Med Genet B Neuropsychiatr Genet, 2005; 135B: 5-9.
    505. Hashimoto R, Yoshida M, Ozaki N, Yamanouchi Y, Iwata N, Suzuki T, Kitajima T, Tatsumi M, Kamijima K, Kunugi H. A missense polymorphism (H204R) of a Rho GTPase-activating protein, the chimerin 2 gene, is associated with schizophrenia in men. Schizophr Res, 2005; 73: 383-385.
    506. Hashimoto R, Suzuki T, Iwata N, Yamanouchi Y, Kitajima T, Kosuga A, Tatsumi M, Ozaki N, Kamijima K, Kunugi H. Association study of the frizzled-3 (FZD3) gene with schizophrenia and mood disorders. J Neural Transm, 2005; 112: 303-307.
    507. Hakamata Y, Takahashi N, Ishihara R, Saito S, Ozaki N, Honjo S, Ono Y, Inada T. No association between monoamine oxidase A promoter polymorphism and personality traits in Japanese females. Neurosci Lett, 2005; 389: 121-123.
    508. Furukawa TA, Streiner DL, Azuma H, Higuchi T, Kamijima K, Kanba S, Ozaki N, Aoba A, Murasaki M, Miura S. Cross-cultural equivalence in depression assessment: Japan-Europe-North American study. Acta Psychiatr Scand, 2005; 112: 279-285.
    509. Arinami T, Ohtsuki T, Ishiguro H, Ujike H, Tanaka Y, Morita Y, Mineta M, Takeichi M, Yamada S, Imamura A, Ohara K, Shibuya H, Suzuki Y, Muratake T, Kaneko N, Someya T, Inada T, Yoshikawa T, Toyota T, Yamada K, Kojima T, Takahashi S, Osamu O, Shinkai T, Nakamura M, Fukuzako H, Hashiguchi T, Niwa SI, Ueno T, Tachikawa H, Hori T, Asada T, Nanko S, Kunugi H, Hashimoto R, Ozaki N, Iwata N, Harano M, Arai H, Ohnuma T, Kusumi I, Koyama T, Yoneda H, Fukumaki Y, Shibata H, Kaneko S, Higuchi H, Yasui-Furukori N, Numachi Y, Itokawa M, Okazaki Y. Genomewide high-density SNP linkage analysis of 236 Japanese families supports the existence of schizophrenia susceptibility Loci on chromosomes 1p, 14q, and 20p. Am J Hum Genet, 2005; 77: 937-944.
    510. Arima M, Shimizu Y, Sowa J, Narita T, Nishi I, Iwata N, Ozaki N, Hashimoto S, Matsunaga K. Psychosomatic analysis of atopic dermatitis using a psychological test. J Dermatol, 2005; 32: 160-168.
    511. Takano A, Uchiyama M, Kajimura N, Mishima K, Inoue Y, Kamei Y, Kitajima T, Shibui K, Katoh M, Watanabe T, Hashimotodani Y, Ozeki Y, Hori T, Yamada N, Toyoshima R, Ozaki N, Okawa M, Nagai K, Takahashi K, Isojima Y, Yamauchi T, Ebisawa T. A Missense Variation in Human Casein Kinase I Epsilon Gene that Induces Functional Alteration and Shows an Inverse Association with Circadian Rhythm Sleep Disorders. Neuropsychopharmacology, 2004; 29: 1901-1909.
    512. Ozaki N. Pharmacogenetics of antipsychotics. Nagoya J Med Sci, 2004; 67: 1-7.
    513. Okada M, Northup J, Ozaki N, Russell J, Linnoila M, Goldman D. Modification of Human 5-HT2C Receptor Function by Cys23Ser, an Abundant, Naturally Occurring Amino Acid Substitution. Mol Psychiatry, 2004; 9: 55-64.
    514. Okada M, Goldman D, Linnoila M, Iwata N, Ozaki N, Northup JK. Comparison of G-Protein Selectivity of Human 5-HT2C and 5-HT1A Receptors. Ann N Y Acad Sci, 2004; 1025: 570-577.
    515. Numakawa T, Yagasaki Y, Ishimoto T, Okada T, Suzuki T, Iwata N, Ozaki N, Taguchi T, Tatsumi M, Kamijima K, Straub RE, Weinberger DR, Kunugi H, Hashimoto R. Evidence of novel neuronal functions of dysbindin, a susceptibility gene for schizophrenia. Hum Mol Genet, 2004; 13: 2699-2708.
    516. Nokura K, Kanbayashi T, Ozeki T, Koga H, Zettsu T, Yamamoto H, Ozaki N, Shimizu T, Kawase T. Hypersomnia, asterixis and cataplexy in association with orexin A-reduced hypothalamic tumor. J Neurol, 2004; 251: 1534-1535.
    517. Munakata K, Tanaka M, Mori K, Washizuka S, Yoneda M, Tajima O, Akiyama T, Nanko S, Kunugi H, Tadokoro K, Ozaki N, Inada T, Sakamoto K, Fukunaga T, Iijima Y, Iwata N, Tatsumi M, Yamada K, Yoshikawa T, Kato T. Mitochondrial DNA 3644T-->C mutation associated with bipolar disorder. Genomics, 2004; 84: 1041-1050.
    518. Kunugi H, Iijima Y, Tatsumi M, Yoshida M, Hashimoto R, Kato T, Sakamoto K, Fukunaga T, Inada T, Suzuki T, Iwata N, Ozaki N, Yamada K, Yoshikawa T. No association between the Val66Met polymorphism of the brain-derived neurotrophic factor gene and bipolar disorder in a Japanese population: a multicenter study. Biol Psychiatry, 2004; 56: 376-378.
    519. Koizumi H, Hashimoto K, Kumakiri C, Shimizu E, Sekine Y, Ozaki N, Inada T, Harano M, Komiyama T, Yamada M, Sora I, Ujike H, Takei N, Iyo M. Association between the glutathione S-transferase M1 gene deletion and female methamphetamine abusers. Am J Med Genet, 2004; 126B: 43-45.
    520. Kobayashi H, Ide S, Hasegawa J, Ujike H, Sekine Y, Ozaki N, Inada T, Harano M, Komiyama T, Yamada M, Iyo M, Shen HW, Ikeda K, Soraa I. Study of Association between {alpha}-Synuclein Gene Polymorphism and Methamphetamine Psychosis/Dependence. Ann N Y Acad Sci, 2004; 1025: 325-334.
    521. Iwata N, Suzuki T, Ikeda M, Kitajima T, Yamanouchi Y, Inada T, Ozaki N. No Association With the Neuregulin 1 Haplotype to Japanese Schizophrenia. Mol Psychiatry, 2004; 9: 126-127.
    522. Iwata N, Inada T, Harano M, Komiyama T, Yamada M, Sekine Y, Iyo M, Sora I, Ujike H, Ozaki N. No association is found between the candidate genes of t-PA/plasminogen system and Japanese methamphetamine-related disorder: a collaborative study by the Japanese Genetics Initiative for Drug Abuse. Ann N Y Acad Sci, 2004; 1025: 34-38.
    523. Itoh K, Hashimoto K, Shimizu E, Sekine Y, Ozaki N, Inada T, Harano M, Iwata N, Komiyama T, Yamada M, Sora I, Nakata K, Ujike H, Iyo M. Association study between brain-derived neurotrophic factor gene polymorphisms and methamphetamine abusers in Japan. Am J Med Genet B Neuropsychiatr Genet, 2004; 132B: 70-73.
    524. Inada T, Iijima Y, Uchida N, Maeda T, Iwashita S, Ozaki N, Harano M, Komiyama T, Yamada M, Sekine Y, Iyo M, Sora I, Ujikec H. No Association Found between the Type 1 Sigma Receptor Gene Polymorphisms and Methamphetamine Abuse in the Japanese Population: A Collaborative Study by the Japanese Genetics Initiative for Drug Abuse. Ann N Y Acad Sci, 2004; 1025: 27-33.
    525. Ikeda M, Iwata N, Suzuki T, Kitajima T, Yamanouchi Y, Kinoshita Y, Inada T, Ozaki N. Association of AKT1 with schizophrenia confirmed in a Japanese population. Biol Psychiatry, 2004; 56: 698-700.
    526. Ide S, Kobayashi H, Tanaka K, Ujike H, Sekine Y, Ozaki N, Inada T, Harano M, Komiyama T, Yamada M, Iyo M, Ikeda K, Sora I. Gene polymorphisms of the mu opioid receptor in methamphetamine abusers. Ann N Y Acad Sci, 2004; 1025: 316-324.
    527. Hashimoto R, Yoshida M, Ozaki N, Yamanouchi Y, Iwata N, Suzuki T, Kitajima T, Tatsumi M, Kamijima K, Kunugi H. Association analysis of the -308G>A promoter polymorphism of the tumor necrosis factor alpha (TNF-alpha) gene in Japanese patients with schizophrenia. J Neural Transm, 2004; 111: 217-221.
    528. Harano M, Uchimura N, Abe H, Ishibashi M, Iida N, Yanagimoto K, Tanaka T, Maeda H, Sora I, Iyo M, Komiyama T, Yamada M, Sekine Y, Inada T, Ozaki N, Ujike H. A Polymorphism of DRD2 Gene and Brain Atrophy in Methamphetamine Psychosis. Ann N Y Acad Sci, 2004; 1025: 307-315.
    529. Deng XX, Shibata HH, Ninomiya HH, Tashiro NN, Iwata NN, Ozaki NN, Fukumaki YY. Association study of polymorphisms in the excitatory amino acid transporter 2 gene (SLC1A2) with schizophrenia. BMC Psychiatry, 2004; 4: 21.
    530. Yamanouchi Y, Iwata N, Suzuki T, Kitajima T, Ikeda M, Ozaki N. Effect of DRD2, 5-HT2A, and COMT genes on antipsychotic response to risperidone. Pharmacogenomics J, 2003; 3: 356-361.
    531. Ujike H, Harano M, Inada T, Yamada M, Komiyama T, Sekine Y, Sora I, Iyo M, Katsu T, Nomura A, Nakata K, Ozaki N. Nine- or fewer repeat alleles in VNTR polymorphism of the dopamine transporter gene is a strong risk factor for prolonged methamphetamine psychosis. Pharmacogenomics J, 2003; 3: 242-247.
    532. Tokura T, Murase T, Toriyama T, Totani Y, Negita M, Akaza K, Ozawa H, Nakagawa A, Nakamura S. Asian variant of CD5+ intravascular large B-cell lymphoma with splenic infarction. Intern Med, 2003; 42: 105-109.
    533. Suzuki T, Iwata N, Kitamura Y, Kitajima T, Yamanouchi Y, Ikeda M, Nishiyama T, Kamatani N, Ozaki N. Association of a haplotype in the serotonin 5-HT4 receptor gene (HTR4) with Japanese schizophrenia. Am J Med Genet B Neuropsychiatr Genet, 2003; 121: 7-13.
    534. Ozaki N, Goldman D, Kaye WH, Plotnicov K, Greenberg BD, Lappalainen J, Rudnick G, Murphy DL. Serotonin transporter missense mutation associated with a complex neuropsychiatric phenotype. Mol Psychiatry, 2003; 8: 933-936.
    535. Ozaki N. Psychopharmacogenetics. In: Encyclopedia of Human Genome, edited by DN Cooper. pp. 917-922, 2003, Nature Publishing Group, London, New York and Tokyo.
    536. Okada T, Toichi M, Sakihama M. Influences of an anticholinergic antiparkinsonian drug, parkinsonism, and psychotic symptoms on cardiac autonomic function in schizophrenia. J Clin Psychopharmacol, 2003; 23: 441-447.
    537. Okada M, Irie S, Sawada M, Urae R, Urae A, Iwata N, Ozaki N, Akazawa K, Nakanishi H. Pepstatin A induces extracellular acidification distinct from aspartic protease inhibition in microglial cell lines. Glia, 2003; 43: 167-174.
    538. Noda M, Yasuda S, Okada M, Higashida H, Shimada A, Iwata N, Ozaki N, Nishikawa K, Shirasawa S, Uchida M, Aoki S, Wada K. Recombinant human serotonin 5A receptors stably expressed in C6 glioma cells couple to multiple signal transduction pathways. J Neurochem, 2003; 84: 222-232.
    539. Kusunoki K, Kitajima T, Ozaki N. Does quazepam influence sleep and daytime activity in healthy adults? Sleep and Biological Rhythms, 2003; 1: 171-172.
    540. Kubota Y, Querel C, Pelion F, Laborit J, Laborit MF, Gorog F, Okada T, Murai T, Sato W, Yoshikawa S, Toichi M, Hayashi T. Facial affect recognition in pre-lingually deaf people with schizophrenia. Schizophr Res, 2003; 61: 265-270.
    541. Toichi M, Kamio Y, Okada T, Sakihama M, Youngstrom EA, Findling RL, Yamamoto K. A lack of self-consciousness in autism. Am J Psychiatry, 2002; 159: 1422-1424.
    542. Sato W, Kubota Y, Okada T, Murai T, Yoshikawa S, Sengoku A. Seeing happy emotion in fearful and angry faces: qualitative analysis of facial expression recognition in a bilateral amygdala-damaged patient. Cortex, 2002; 38: 727-742.
    543. Iwase T, Kajimura N, Uchiyama M, Ebisawa T, Yoshimura K, Kamei Y, Shibui K, Kim K, Kudo Y, Katoh M, Watanabe T, Nakajima T, Ozeki Y, Sugishita M, Hori T, Ikeda M, Toyoshima R, Inoue Y, Yamada N, Mishima K, Nomura M, Ozaki N, Okawa M, Takahashi K, Yamauchi T. Mutation screening of the human Clock gene in circadian rhythm sleep disorders. Psychiatry Res, 2002; 109: 121-128.
    544. Hirano S, Sato T, Narita T, Kusunoki K, Ozaki N, Kimura S, Takahashi T, Sakado K, Uehara T. Evaluating the state dependency of the Temperament and Character Inventory dimensions in patients with major depression: a methodological contribution. J Affect Disord, 2002; 69: 31-38.

研究キーワード

児童思春期精神医学、 統合失調症、 うつ病、 双極性障害、 認知症、 自閉スペクトラム症、 不安症、 身体症状症、 周産期、 産業衛生医学、 歯科口腔外科学、 がん、 臓器移植、 心不全、 オミックス、 ゲノム、 モデル動物、 iPS細胞、 神経画像、 死後脳、 疼痛、 向精神薬、 エピゲノム

精神医学／発達老年医学／親と子どもの心療学　独自ホームページ

糖鎖生命コア研究所　iGCORE

精神医学　オープンキャンパス

大学院の概要；研究と教育の基本方針

精神疾患の病態メカニズムを解明する研究や、臨床実践に基づいた研究を行っています。これらの研究は、すぐに新薬の開発に直結するわけではありませんが、将来的により良い治療法の確立や、薬物の副作用による社会生活への支障を解消するためには欠かせません。そのため、「より質の高いエビデンス」を構築することを推進しています。

文献検索や批判的な吟味、研究デザイン、実験ノートの書き方、データ解析、データの提示方法、サイエンティフィックライティングといった、研究を進める上で必要となる基本的な技術を習得し、将来の研究活動の基盤を築くだけでなく、臨床の場でも活用できる科学的視点を養えるよう指導しています。

また、医学部卒業生に限らず、心理学関連の学科や薬学部、保健学部など、他分野を卒業した方々の参加も歓迎しています。

研究に専念する博士課程の大学院生としての進学と、基幹施設や連携施設で精神科医としての業務を継続しながら社会人大学院生として学び続ける選択肢があります。

教育・研修についてはこちらもご参照ください。