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研究報告:2021年

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1.       Nishi R, Koike H, Ohyama K, Fukami Y, Iijima M, Sobue G, Katsuno M. Association Between IL-5 Levels and the Clinicopathologic Features of Eosinophilic Granulomatosis With Polyangiitis. Neurology. 96: 226-229, 2021

2.       Furukawa S, Kunii M, Doi H, Kondo N, Ogura A, Hirabuki K, Itoh T, Matsumoto N, Tanaka F, Katsuno M, Ito Y. Case Report: Severe Osteoporosis and Preventive Therapy in RNA Polymerase III-Related Leukodystrophy. Front Neurol. 12: 622355, 2021

3.       Harada Y, Sheng S, Thombre VA, Ounpraseuth S, Tommee CG, Annapureddy AR, Kamran M, Jasti MS, Katsuno M, Yadala S, Veerapaneni K, Kapoor N, Kovvuru S, Onteddu SR, Nalleballe K. A neuromuscular-based analysis of the open payments program. Muscle Nerve. 63: 96-99, 2021

4.       Tsuboi T, Charbel M, Peterside DT, Rana M, Elkouzi A, Deeb W, Ramirez-Zamora A, Lemos Melo Lobo Jofili Lopes J, Almeida L, Zeilman PR, Eisinger RS, Foote KD, Okromelidze L, Grewal SS, Okun MS, Middlebrooks EH. Pallidal Connectivity Profiling of Stimulation-Induced Dyskinesia in Parkinson's Disease. Mov Disord. 36: 380-388, 2021

5.       Hirunagi T, Sahashi K, Tachikawa K, Leu AI, Nguyen M, Mukthavaram R, Karmali PP, Chivukula P, Tohnai G, Iida M, Onodera K, Ohyama M, Okada Y, Okano H, Katsuno M. Selective suppression of polyglutamine-expanded protein by lipid nanoparticle-delivered siRNA targeting CAG expansions in the mouse CNS. Mol Ther Nucleic Acids. 24: 1-10, 2021

6.       Nakamura R, Tohnai G, Atsuta N, Nakatochi M, Hayashi N, Watanabe H, Yokoi D, Watanabe H, Katsuno M, Izumi Y, Taniguchi A, Kanai K, Morita M, Kano O, Kuwabara S, Oda M, Abe K, Aoki M, Aiba I, Okamoto K, Mizoguchi K, Hattori N, Nakashima K, Kaji R, Sobue G; Japanese Consortium for Amyotrophic Lateral Sclerosis Research (JaCALS). Genetic and functional analysis of KIF5A variants in Japanese patients with sporadic amyotrophic lateral sclerosis. Neurobiol Aging. 97: e11-147.e17, 2021

7.       Koike H, Mouri N, Fukami Y, Iijima M, Matsuo K, Yagi N, Saito A, Nakamura H, Takahashi K, Nakae Y, Okada Y, Tanaka F, Sobue G, Katsuno M. Two distinct mechanisms of neuropathy in immunoglobulin light chain (AL) amyloidosis. J Neurol Sci. 421: 117305, 2021

8.       Hayashi N, Sone J, Fukami Y, Yoshida Y, Kuno S, Shimada K, Atsuta N, Nakamura T, Higuchi O, Katsuno M. Severe myasthenia gravis with anti-LRP4 antibodies and Hodgkin lymphoma. Muscle Nerve. 63: E2-E4, 2021

9.       Kusama K, Nakae Y, Tada M, Higashiyama Y, Miyaji Y, Yamaura G, Kunii M, Tanaka K, Ohyama K, Koike H, Joki H, Doi H, Koyano S, Tanaka F. Hepatitis B Virus-related Vasculitic Neuropathy in an Inactive Virus Carrier Treated with Intravenous Immunoglobulin. Intern Med. 59: 3075-3078, 2021

10.    Ueda M, Sekijima Y, Koike H, Yamashita T, Yoshinaga T, Ishii T, Ando Y. Monitoring of asymptomatic family members at risk of hereditary transthyretin amyloidosis for early intervention with disease-modifying therapies. J Neurol Sci. 414: 116813, 2021

11.    Koike H, Katsuno M. Macrophages and Autoantibodies in Demyelinating Diseases. Cells. 10: 844, 2021

12.    Riku Y, Seilhean D, Duyckaerts C, Boluda S, Iguchi Y, Ishigaki S, Iwasaki Y, Yoshida M, Sobue G, Katsuno M. Pathway from TDP-43-Related Pathology to Neuronal Dysfunction in Amyotrophic Lateral Sclerosis and Frontotemporal Lobar Degeneration. Int J Mol Sci. 22: 3843, 2021

13.    Ando T, Nakamura R, Kuru S, Yokoi D, Atsuta N, Koike H, Suzuki M, Hara K, Iguchi Y, Harada Y, Yoshida Y, Hattori M, Murakami A, Noda S, Kimura S, Sone J, Nakamura T, Goto Y, Mano K, Okada H, Okuda S, Nishino I, Ogi T, Sobue G, Katsuno M. The wide-ranging clinical and genetic features in Japanese families with valosin-containing protein proteinopathy. Neurobiol Aging. 100: 120.e1-120.e6, 2021

14.    Lövestam S, Schweighauser M, Matsubara T, Murayama S, Tomita T, Ando T, Hasegawa K, Yoshida M, Tarutani A, Hasegawa M, Goedert M, Scheres SHW. Seeded assembly in vitro does not replicate the structures of α-synuclein filaments from multiple system atrophy. FEBS Open Bio. 11: 999-1013, 2021

15.    Wong JK, Hu W, Barmore R, Lopes J, Moore K, Legacy J, Tahafchi P, Jackson Z, Judy JW, Raike RS, Wang A, Tsuboi T, Okun MS, Almeida L. Safety and Tolerability of Burst-Cycling Deep Brain Stimulation for Freezing of Gait in Parkinson's Disease. Front Hum Neurosci. 15: 651168, 2021

16.    Homma H, Tanaka H, Jin M, Jin X, Huang Y, Yoshioka Y, Bertens CJ, Tsumaki K, Kondo K, Shiwaku H, Tagawa K, Akatsu H, Atsuta N, Katsuno M, Furukawa K, Ishiki A, Waragai M, Ohtomo G, Iwata A, Yokota T, Inoue H, Arai H, Sobue G, Sone M, Fujita K, Okazawa. DNA damage in embryonic neural stem cell determines FTLDs' fate via early-stage neuronal necrosis. Life Sci Alliance. 4: e202101022, 2021

17.    Li J, Durose WW, Ito J, Kakita A, Iguchi Y, Katsuno M, Kunisawa K, Shimizu T, Ikenaka K. Exploring the factors underlying remyelination arrest by studying the post-transcriptional regulatory mechanisms of cystatin F gene. J Neurochem. 157: 2070-2090, 2021

18.    Koike H, Katsuno M. The Ultrastructure of Tissue Damage by Amyloid Fibrils. Molecules. 26: 4611, 2021

19.    Kumutpongpanich T, Ogasawara M, Ozaki A, Ishiura H, Tsuji S, Minami N, Hayashi S, Noguchi S, Iida A, Nishino I; OPDM_LRP12 Study Group; Mori-Yoshimura M, Oya Y, Ono K, Shimizu T, Kawata A, Shimohama S, Toyooka K, Endo K, Toru S, Sasaki O, Isahaya K, Takahashi MP, Iwasa K, Kira JI, Yamamoto T, Kawamoto M, Hamano T, Sugie K, Eura N, Shiota T, Koide M, Sekiya K, Kishi H, Hideyama T, Kawai S, Yanagimoto S, Sato H, Arahata H, Murayama S, Saito K, Hara H, Kanda T, Yaguchi H, Imai N, Kawagashira Y, Sanada M, Obara K, Kaido M, Furuta M, Kurashige T, Hara W, Kuzume D, Yamamoto M, Tsugawa J, Kishida H, Ishizuka N, Morimoto K, Tsuji Y, Tsuneyama A, Matsuno A, Sasaki R, Tamakoshi D, Abe E, Yamada S, Uzawa A.     Clinicopathologic Features of Oculopharyngodistal Myopathy With LRP12 CGG Repeat Expansions Compared With Other Oculopharyngodistal Myopathy Subtypes. JAMA Neurol. 78: 853-863, 2021

20.    Tsuboi T, Wong JK, Eisinger RS, Okromelidze L, Burns MR, Ramirez-Zamora A, Almeida L, Wagle Shukla A, Foote KD, Okun MS, Grewal SS, Middlebrooks EH. Comparative connectivity correlates of dystonic and essential tremor deep brain stimulation. Brain. 144: 1774-1786, 2021

21.    Kawabata K, Bagarinao E, Watanabe H, Maesawa S, Mori D, Hara K, Ohdake R, Masuda M, Ogura A, Kato T, Koyama S, Katsuno M, Wakabayashi T, Kuzuya M, Hoshiyama M, Isoda H, Naganawa S, Ozaki N, Sobue G. Bridging large-scale cortical networks: Integrative and function-specific hubs in the thalamus. iScience. 24: 103106, 2021

22.    Ebina J, Hara K, Watanabe H, Kawabata K, Yamashita F, Kawaguchi A, Yoshida Y, Kato T, Ogura A, Masuda M, Ohdake R, Mori D, Maesawa S, Katsuno M, Kano O, Sobue G. Individual voxel-based morphometry adjusting covariates in multiple system atrophy. Parkinsonism Relat Disord. 90: 114-119, 2021

23.    Kanda M, Shimizu D, Nakamura S, Sawaki K, Umeda S, Miwa T, Tanaka H, Inokawa Y, Hattori N, Hayashi M, Tanaka C, Nakayama G, Iguchi YKatsuno M, Kodera Y. Blockade of CHRNB2 signaling with a therapeutic monoclonal antibody attenuates the aggressiveness of gastric cancer cells. Oncogene. 40: 5495-5504,2021

24.    Ando T, Sato T, Kurahashi S, Kawaguchi Y, Kagaya Y, Ozawa Y, Hirano S, Goto Y, Mano K, Yokoi S, Nakamura T, Murakami A, Noda S, Kimura S, Sone J, Kuru S, Sobue G, Katsuno M. A case of sporadic late-onset nemaline myopathy with monoclonal gammopathy of undetermined significance: long-term observation of neurological symptoms after autologous stem-cell transplantation. Nagoya J Med Sci. 83: 641-647, 2021

25.    Koike H, Iguchi Y, Sahashi KKatsuno M. Significance of Oligomeric and Fibrillar Species in Amyloidosis: Insights into Pathophysiology and Treatment. Molecules. 26: 5091, 2021

26.    Koike HKatsuno M. Emerging infectious diseases, vaccines and Guillain-Barré syndrome. Neurol Ther. 10: 523-537, 2021

27.    Harada Y, Nakamura T, Suzuki M, Ueda M, Hirayama M, Katsuno M. Impaired pain processing and its association with attention disturbance in patients with amyotrophic lateral sclerosis. Neurol Sci. 42: 3327-3335, 2021

28.    Holanda VM, Eisinger RS, Almeida L, Tsuboi T, Wang H, Okun MS, Deeb W, Patterson A, Wagle Shukla A, Lobo Lopes J, Foote KD. Evolution of Globus Pallidus Targeting for Parkinson's and Dystonia Deep Brain Stimulation: A 15-Year Experience. Front Neurol. 12: 679918, 2021.

29.    Ando T, Yokoi F, Riku Y, Akagi A, Miyahara H, Hasegawa M, Katsuno M, Yoshida M, Iwasaki Y. The hot cross bun sign in corticobasal degeneration. Neuropathology. 41: 376-380, 2021

30.    Fukami Y, Iijima M, Koike H, Yamada S, Hashizume AKatsuno M. Association of serum neurofilament light chain levels with clinicopathology of chronic inflammatory demyelinating polyneuropathy, including NF155 reactive patients. J Neurol. 268: 3835-3844, 2021

31.    Yamada S, Hashizume A, Hijikata Y, Ito D, Kishimoto Y, Iida M, Koike H, Hirakawa AKatsuno M. Ratio of urinary N-terminal titin fragment to urinary creatinine is a novel biomarker for amyotrophic lateral sclerosis. J Neurol Neurosurg Psychiatry. 92: 1072-1079, 2021

32.    Middlebrooks EH, Okromelidze L, Wong JK, Eisinger RS, Burns MR, Jain A, Lin HP, Yu J, Opri E, Horn A, Goede LL, Foote KD, Okun MS, Quiñones-Hinojosa A, Uitti RJ, Grewal SS, Tsuboi T. Connectivity correlates to predict essential tremor deep brain stimulation outcome: Evidence for a common treatment pathway. Neuroimage Clin. 32: 102846, 2021

33.    Watanabe H, Bagarinao E, Maesawa S, Hara K, Kawabata K, Ogura A, Ohdake R, Shima S, Mizutani Y, Ueda A, Ito M, Katsuno M, Sobue G. Characteristics of Neural Network Changes in Normal Aging and Early Dementia. Front Aging Neurosci. 13: 747359, 2021

34.    Maesawa S, Mizuno S, Bagarinao E, Watanabe H, Kawabata K, Hara K, Ohdake R, Ogura A, Mori D, Nakatsubo D, Isoda H, Hoshiyama M, Katsuno M, Saito R, Ozaki N, Sobue G. Resting State Networks Related to the Maintenance of Good Cognitive Performance During Healthy Aging. Front Hum Neurosci. 15: 753836, 2021

35.    Koike H, Katsuno M. Paraproteinemia and neuropathy. Neurol Sci. 42: 4489-4501, 2021

36.    Sommer C, Carroll AS, Koike HKatsuno M, Ort N, Sobue G, Vucic S, Spies JM, Doppler K, Kiernan MC. Nerve biopsy in acquired neuropathies. J Peripher Nerv Syst. 26: S21-S41, 2021

37.    Oishi M, Mukaino A, Kunii M, Saito A, Arita Y, Koike H, Higuchi O, Maeda Y, Abiru N, Yamaguchi N, Kawano H, Tsuiki E, Tanaka T, Matsuo H, Katsuno M, Tanaka F, Tsujino A, Nakane S. Association between neurosarcoidosis with autonomic dysfunction and anti-ganglionic acetylcholine receptor antibodies. J Neurol. 268: 4265-4279, 2021

38.    Riku Y, Yoshida M, Tamura T, Kamijo M, Yasui K, Kameyama T, Katsuno M, Sobue G, Iwasaki Y. Unexpected postmortem diagnoses in cases of clinically diagnosed amyotrophic lateral sclerosis. Neuropathology. 41: 457-467, 2021

39.    Tanaka Y, Tsuboi T, Watanabe H, Torii J, Nakatsubo D, Maesawa S, Sato M, Hiraga K, Satake Y, Yokoi K, Hattori M, Kawabata K, Hara K, Yamamoto M, Sobue G, Katsuno M. Instability of speech in Parkinson disease patients with subthalamic nucleus deep brain stimulation. Parkinsonism Relat Disord. 93: 8-11, 2021

40.    Noda S, Murakami A, Kimura S, Minamiyama M, Katsuno M, Kuru S. Duchenne Muscular Dystrophy Successfully Treated with Aripiprazole in a Patient with Autism Spectrum Disorder Symptoms Including Irritability. Intern Med. 60: 3983-3986, 2021

41.    Koike H, Chiba A, Katsuno M. Emerging Infection, Vaccination, and Guillain-Barré Syndrome: A Review. Neurol Ther. 10: 523-537, 2021

42.    Koike H, Okumura T, Murohara T, Katsuno M. Multidisciplinary Approaches for Transthyretin Amyloidosis. Cardiol Ther. 10: 289-311, 2021

43. Kato S, Bagarinao E, Isoda H, Koyama S, Watanabe H, Maesawa S, Mori D, Hara KKatsuno M, Hoshiyama M, Naganawa S, Ozaki N, Sobue G. Effects of Head Motion on the Evaluation of Age-related Brain Network Changes Using Resting State Functional MRI. Magn Reson Med Sci. 20: 338-346, 2021

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