研究室紹介LABORATORY

腎臓内科学

KEYWORDS

  • 再生医療
  • 嚢胞腎
  • 補体
  • ネフローゼ症候群
  • 間葉系幹細胞
  • 炎症制御
  • 異分野融合
  • 臓器再生
  • Single cell RNA-seq
  • 空間トランスクリプトーム
  • 白血球レジストリー研究
  • 細胞外小胞
  • iPS細胞
  • microRNA
  • 非典型溶血性尿毒症症候群
  • 難治性ネフローゼ症候群
  • エネルギー代謝
  • ループス腎炎
  • 腹膜透析
  • 腎不全
  • 臨床疫学
  • 糸球体腎炎
  • 腎生検
  • 血液透析
  • 長時間透析
  • リアルワールドデータ  

HEAD

丸山 彰一

教授

研究者総覧

LAB MEMBER

構成員名 役職 研究者総覧
小杉 智規 准教授/特命教授 研究者総覧
加藤 規利 講師 研究者総覧
古橋 和拡 講師 研究者総覧
前田 佳哉輔 病院講師/医局長 研究者総覧
田中 章仁 病院講師 研究者総覧
尾関 貴哉 助教 研究者総覧
長田 啓史 病院助教 研究者総覧
西堀 暢浩 病院助教 研究者総覧

CONTACT

Email med◎t.mail.nagoya-u.ac.jp（送信の際は◎を@に変更してください）
HP 腎臓内科 独自ホームページ

OUTLINE

本講座は、2002年1月に松尾清一腎臓内科教授を主任教授として開設されました。2010年4月松尾教授の病院長再任時に、丸山彰一准教授が特命教授に任命され、さらに2016年4月松尾清一教授名古屋大学総長、丸山主任教授就任を機に新体制となりました。2026年1月現在、本講座は丸山教授以下、准教授1名、講師2名、病院講師2名、助教1名、病院助教3名、特任准教授１名、特任講師1名の12名の教員に加えて、医員5名、大学院生2４名(内海外からの留学生3名)、客員研究者5名、国外留学者2名で編成されています。また2005年2月開設の腎不全治療システム学寄附講座は、2010年2月腎不全総合治療学寄附講座、2015年2月腎不全システム治療学寄附講座と名称変更し、現在教授1名、講師1名、助教2名の４名の教員を中心に腹膜透析分野の臨床・研究両分野で活動しています。さらに、他部署における教官5名を合わせ、合計57名の布陣で、大学の使命である①臨床②教育③研究の腎臓分野での推進に励んでおります。

RESEARCH PROJECTS

再生グループ

  • 脂肪由来間葉系幹細胞を用いた新規腎疾患への治療法開発
  • 細胞治療用中空糸カラムの開発
  • 生体がもつ巧妙な炎症制御機構の解明から治療応用へ
  • 再生異種移植療法技術の開発
  • Biological clinical research
  • リアルワールドデータ解析

生化学グループ

  • miRNAを作用点とした腎疾患治療開発
  • 多発性嚢胞腎の新規治療開発
  • 本邦における非典型溶血性尿毒症症候群（aHUS）の全国調査研究
  • aHUS、および補体関連腎疾患の新規診断法開発
  • 治療抵抗性ネフローゼ症候群におけるポドサイト傷害機序の解明と、治療開発
  • ポドサイト傷害におけるエネルギー代謝動態の解明から治療応用
  • ループス腎炎におけるポドサイト傷害機序の解明

腹膜透析グループ

  • 腹膜機能に関与する免疫系（主に補体系）の役割解明
  • 腎不全における慢性炎症の腹膜に与える影響の解明
  • 腹膜線維化・被嚢性腹膜硬化症（EPS）の病態解明
  • 東海地区におけるPDレジストリを用いた臨床研究
  • C3腎症の病態解明
  • 疾患モデルマウスを用いたaHUS/TMAの病態解明
  • マラリアにおける補体系の役割解明

臨床研究グループ

  • 腎生検レジストリー研究
  • 腎代替療法レジストリ研究
  • リアルワールドデータ解析・実装研究

BIBLIOGRAPHY

2024
  1. Nakamura Y, Inaguma D, Imaizumi T, Kurasawa S, Hishida M, Okazaki M, Fujishima Y, Nishibori N, Suzuki K, Takeda Y, Maruyama S. Association between stopping renin-angiotensin system inhibitors immediately before hemodialysis initiation and subsequent cardiovascular events. Hypertens Res. 2024;47(5):1372-1379.
  2. Fujieda K, Saito S, Tanaka A, Furuhashi K, Ozeki T, Yasuda Y, Sano Y, Ishida S, Maruyama S. A case of non-traumatic rectus sheath hematoma in a post-kidney transplant patient undergoing catheter embolization during anticoagulation treatment for atrial fibrillation. CEN Case Rep. 2024. Epub ahead of print.
  3. Nishibori N, Okazaki M, Miura Y, Hishida M, Kurasawa S, Imaizumi T, Kato N, Kosugi T, Kuro-O M, Kasuga H, Kaneda F, Maruyama S. Association of calciprotein particles with serum phosphorus among patients undergoing conventional and extended-hours haemodialysis. Clin Kidney J. 2024;17(6):sfae121.
  4. Komatsu H, Fujimoto S, Sato Y, Yasuda T, Yasuda Y, Matsuzaki K, Hirano K, Kawamura T, Yokoo T, Suzuki Y, Maruyama S. Effect of tonsillectomy combined with steroid pulse therapy upon IgA nephropathy depending on proteinuria status at diagnosis: a nationwide multicenter cohort study in Japan. Clin Exp Nephrol. 2024. Epub ahead of print.
  5. Kojima M, Shibata M, Tomita S, Ueda R, Kasai R, Yamamoto E, Ban A, Suzuki S, Maruyama S. Recurrent localized fever caused by cryoglobulinemic vasculitis following hemodialysis: A case report. CEN Case Rep. 2024. Epub ahead of print.
  6. Tatematsu Y, Imaizumi T, Michihata N, Kato N, Kumazawa R, Matsui H, Fushimi K, Yasunaga H, Maruyama S. Annual trends in atypical haemolytic uremic syndrome management in Japan and factors influencing early diagnosis and treatment: a retrospective study. Sci Rep. 2024;14(1):18265.
  7. Tanaka A, Furuhashi K, Fujieda K, Horinouchi A, Maeda K, Saito S, Mimura T, Saka Y, Naruse T, Ishimoto T, Kato N, Kosugi T, Kinoshita F, Kuwatsuka Y, Nakai Y, Maruyama S. Safety and Tolerability of ADR-001 Therapy for Immunoglobulin A Nephropathy. Kidney360. 2024. Epub ahead of print.
  8. Owaki A, Tanaka A, Furuhashi K, Watanabe Y, Koshi-Ito E, Imaizumi T, Maruyama S. Prognosis of microscopic polyangiitis is well predictable in the first 2 weeks of treatment. Clin Exp Nephrol. 2024;28(7):701-706.
  9. Onogi C, Watanabe Y, Tanaka A, Furuhashi K, Maruyama S. Mortality and hyperkalaemia-associated hospitalisation in patients with chronic kidney disease: comparison of sodium zirconium cyclosilicate and sodium/calcium polystyrene sulfonate. Clin Kidney J. 2024;17(2):sfae021.
  10. Fujieda K, Tanaka A, Kikuchi R, Takai N, Saito S, Yasuda Y, Sano Y, Kato M, Furuhashi K, Maruyama S. Changes in antibody titer after four and five doses of the SARS-CoV-2 vaccine in Japanese post-kidney transplant patients. Ther Apher Dial. 2024;28(4):489-498.
  11. Fujieda K, Saito S, Tanaka A, Furuhashi K, Yasuda Y, Sano Y, Kato M, Maruyama S. A case of late-onset organizing pneumonia following COVID-19 infection in a post-kidney transplant patient. CEN Case Rep. 2024. Epub ahead of print.
  12. Hori M, Takahashi H, Kondo C, Hayashi F, Tokoroyama S, Mori Y, Tsujita M, Shirasawa Y, Takeda A, Morozumi K, Maruyama S. Association between serum 25-hydroxyvitamin D levels and sarcopenia in patients undergoing chronic haemodialysis. Am J Nephrol. 2024;14(4):574-583.
  13. Kurasawa S, Imaizumi T, Kondo T, Hishida M, Okazaki M, Nishibori N, Takeda Y, Kasuga H, Maruyama S. Relationship between peak aortic jet velocity and progression of aortic stenosis in patients undergoing hemodialysis. Int J Cardiol. 2024:131822.
  14. Kurasawa S, Kato S, Ozeki T, Akiyama S, Ishimoto T, Mizuno M, Tsuboi N, Kato N, Kosugi T, Maruyama S; J-MARINE collaborators. Rationale and design of the Japanese Biomarkers in Nephrotic Syndrome (J-MARINE) study. Clin Exp Nephrol. 2024;28(5):431-439.
  15. Kurasawa S, Kato S, Ozeki T, Akiyama S, Ishimoto T, Mizuno M, Tsuboi N, Kato N, Kosugi T, Maruyama S; J-MARINE collaborators. Rationale and design of the Japanese Biomarkers in Nephrotic Syndrome (J-MARINE) study. Clin Exp Nephrol. 2024. Epub ahead of print.
  16. Tanaka A, Watanabe Y, Furuhashi K, Saito S, Yasuda Y, Kosugi T, Sano Y, Kato M, Maruyama S. Establishment of an adverse effect prevention protocol on plasma exchange using fresh frozen plasma prior to ABO-incompatible living donor kidney transplantation at our hospital. Ther Apher Dial. 2024;28(1):152-157.
2023
  1. Aoi T, Tanaka A, Furuhashi K, Ikeya M, Shimizu A, Arioka Y, Kushima I, Ozaki N, Maruyama S. ＜Editors' Choice＞ Mesenchymal stem/stromal cells generated from induced pluripotent stem cells are highly resistant to senescence. Nagoya J Med Sci. 2023;85(4):682-690.
  2. Hori M, Takahashi H, Kondo C, Matsuoka Y, Tsujita M, Nishihira M, Uchida K, Takeda A, Morozumi K, Maruyama S. Coexistence of low muscle mass and osteoporosis as a predictor of fragility fractures in long-term kidney transplant recipients. Am J Nephrol. 2023;54(11-12):489-497.
  3. Hori M, Yasuda K, Takahashi H, Morozumi K, Maruyama S. The association of low serum magnesium levels with frailty among hemodialysis patients. Sci Rep. 2023;13(1):14982.
  4. Watanabe Y, Tanaka A, Furuhashi K, Maruyama S. Current status of low-density lipoprotein apheresis treatment for patients with peripheral artery disease and chronic kidney disease in Japanese clinical database. Ther Apher Dial. 2023;27(6):1000-1009.
  5. Watanabe T, Maeda K, Kato N, Seko H, Sugimura M, Sato Y, Ryuge A, Kato S, Kadomatsu K, Maruyama S, Kosugi T. Basigin is released in extracellular vesicles derived from the renal tubular epithelium in response to albuminuria. Nephrology (Carlton). 2023;28(11):629-638.
  6. Kato S, Kuwatsuka Y, Ando M, Tatematsu Y, Nishibori N, Maruyama S. Rationale and study design of a randomized controlled trial to investigate the renoprotective effect of canagliflozin assessed by test of renal hemodynamics in diabetic kidney disease (the FAGOTTO study). BMC Nephrol. 2023;24(1):228.
  7. Hori M, Yasuda K, Takahashi H, Aoi T, Mori Y, Tsujita M, Shirasawa Y, Kondo C, Hashimoto T, Koyama H, Morozumi K, Maruyama S. The Impact of Liver Chemistries on Respiratory Failure among Hemodialysis Patients with COVID-19 during the Omicron Wave. Intern Med. 2023;62(18):2617-2625.
  8. Maruyama S, Kurasawa S, Hayashi T, Nangaku M, Narita I, Hirakata H, Tanabe K, Morita S, Tsubakihara Y, Imai E, Akizawa T; PREDICT Investigators. Higher hemoglobin levels using darbepoetin alfa and kidney outcomes in advanced chronic kidney disease without diabetes: a prespecified secondary analysis of the PREDICT trial. Clin Exp Nephrol. 2023;27(9):757-766.
  9. Nakamura Y, Kato N, Tatematsu Y, Arai Y, Mori N, Shibata K, Yamazaki M, Yasui H, Fujiwara S, Yamakawa T, Maruyama S. Clinical characteristics of anti- GBM disease with thrombotic microangiopathy: a case report and literature review. CEN Case Rep. 2023:1-8.
  10. Kurasawa S, Imaizumi T, Maruyama S, Tanaka K, Kubo Y, Nagayoshi M, Ikezaki H, Suzuki S, Koyama T, Koriyama C, Kadota A, Katsuura-Kamano S, Kuriki K, Wakai K, Matsuo K. Association of kidney function with cancer incidence and its influence on cancer risk of smoking: The Japan Multi-Institutional Collaborative Cohort Study. Int J Cancer. 2023;153(4):732-741.
  11. Matsuzaki T, Watanabe Y, Tanaka A, Furuhashi K, Saito S, Maruyama S. Prognosis and incidence of infections in chronic kidney disease patients with membranous nephropathy enrolled in a large Japanese clinical claims database. BMC Nephrol. 2023;24(1):126.
  12. Kurasawa S, Okazaki M, Imaizumi T, Kondo T, Hishida M, Nishibori N, Takeda Y, Kasuga H, Maruyama S. Number of calcified aortic valve leaflets: natural history and prognostic value in patients undergoing haemodialysis. Eur Heart J Cardiovasc Imaging. 2023;24(7):909-920.
  13. Shirai S, Yasuda T, Kumagai H, Matsunobu H, Ichikawa D, Shibagaki Y, Yasuda Y, Matsuzaki K, Hirano K, Kawamura T, Suzuki Y, Maruyama S. Prognostic factors of IgA nephropathy presenting with mild proteinuria at the time of diagnosis (a multicenter cohort study). Clin Exp Nephrol. 2023;27(4):340-348.
2022
  1. Imai K, Ishimoto T, Doke T, Tsuboi T, Watanabe Y, Katsushima K, Suzuki M, Oishi H, Furuhashi K, Ito Y, Kondo Y, Maruyama S. Long non-coding RNA lnc- CHAF1B-3 promotes renal interstitial fibrosis by regulating EMT-related genes in renal proximal tubular cells. Mol Ther Nucleic Acids. 2022;31:139-150.
  2. Kobayashi K, Ozeki T, Kim H, Imai M, Kojima H, Iguchi D, Fukui S, Suzuki M, Suzuki Y, Maruyama S, Ito Y, Mizuno M. Long-term peritoneal dialysate exposure modulates expression of membrane complement regulators in human peritoneal mesothelial cells. Front Med (Lausanne). 2022;9:972592.
  3. Muto R, Fukuta S, Watanabe T, Shindo Y, Kanemitsu Y, Kajikawa S, Yonezawa T, Inoue T, Ichihashi T, Shiratori Y, Maruyama S. Predicting oxygen requirements in patients with coronavirus disease 2019 using an artificial intelligence- clinician model based on local non-image data. Front Med (Lausanne). 2022;9:1042067.
  4. Kitai H, Kato N, Ogami K, Komatsu S, Watanabe Y, Yoshino S, Koshi E, Tsubota S, Funahashi Y, Maeda T, Furuhashi K, Ishimoto T, Kosugi T, Maruyama S, Kadomatsu K, Suzuki HI. Systematic characterization of seed overlap microRNA cotargeting associated with lupus pathogenesis. BMC Biol. 2022;20(1):248.
  5. Morooka H, Yamamoto T, Tanaka A, Furuhashi K, Miyagawa Y, Maruyama S. Influence of COVID-19 on the 10-year carbon footprint of the Nagoya University Hospital and medical research centre. Global Health. 2022;18(1):92.
  6. Imaizumi T, Toda T, Maekawa M, Sakurai D, Hagiwara Y, Yoshida Y, Ando M, Maruyama S. Identifying high-risk population of depression: association between metabolic syndrome and depression using a health checkup and claims database. Sci Rep. 2022;12(1):18577.
  7. Shimamura Y, Furuhashi K, Tanaka A, Karasawa M, Nozaki T, Komatsu S, Watanabe K, Shimizu A, Minatoguchi S, Matsuyama M, Sawa Y, Tsuboi N, Ishimoto T, Suzuki HI, Maruyama S. Mesenchymal stem cells exert renoprotection via extracellular vesicle-mediated modulation of M2 macrophages and spleen-kidney network. Commun Biol. 2022;5(1):753.
  8. Hashimoto Y, Kato S, Kuro-O M, Miura Y, Itano Y, Ando M, Kuwatsuka Y, Maruyama S. Impact of etelcalcetide on fibroblast growth factor-23 and calciprotein particles in patients with secondary hyperparathyroidism undergoing haemodialysis. Nephrology (Carlton). 2022;27(9):763-770.
  9. Watanabe Y, Tanaka A, Furuhashi K, Saito S, Maruyama S. Mortality and Cardiovascular Events in Patients With Chronic Kidney Disease and Sleep Apnea Syndrome. Front Med (Lausanne). 2022;9:899359.
  10. Tanaka A, Furuhashi K, Fujieda K, Maeda K, Saito S, Mimura T, Saka Y, Naruse T, Ishimoto T, Kosugi T, Kinoshita F, Kuwatsuka Y, Shimizu S, Nakai Y, Maruyama S. Protocol for a Phase 1, Open-Label, Multiple-Center, Dose-Escalation Study to Evaluate the Safety and Tolerability of ADR-001 in the Treatment of Immunoglobulin A Nephropathy. Front Med (Lausanne). 2022;9:883168.
  11. Hori M, Yasuda K, Takahashi H, Kondo C, Shirasawa Y, Ishimaru Y, Sekiya Y, Morozumi K, Maruyama S. Effects of bone turnover status on the efficacy and safety of denosumab among haemodialysis patients. Sci Rep. 2022;12(1):7781.
  12. Fujieda K, Tanaka A, Kikuchi R, Takai N, Saito S, Yasuda Y, Fujita T, Kato M, Furuhashi K, Maruyama S. Antibody response to double SARS-CoV-2 mRNA vaccination in Japanese kidney transplant recipients. Sci Rep. 2022;12(1):6850.
  13. Minatoguchi S, Saito S, Furuhashi K, Sawa Y, Okazaki M, Shimamura Y, Kaihan AB, Hashimoto Y, Yasuda Y, Hara A, Mizutani Y, Ando R, Kato N, Ishimoto T, Tsuboi N, Esaki N, Matsuyama M, Shiraki Y, Kobayashi H, Asai N, Enomoto A, Maruyama S. A novel renal perivascular mesenchymal cell subset gives rise to fibroblasts distinct from classic myofibroblasts. Sci Rep. 2022 ;12(1):5389.
  14. Hori M, Yasuda K, Takahashi H, Matsuoka Y, Tsujita M, Nishihira M, Uchida K, Morozumi K, Maruyama S. Lateral spine dual-energy X-ray absorptiometry and the risk of fragility fractures in long-term kidney graft recipients. Clin Exp Nephrol. 2022;26(7):724-732.
  15. Kozaki Y, Morinaga T, Fukatsu A, Ito T, Ishimoto T, Kosugi T, Inaguma D, Tamai H, Maruyama S. Sex differences in clinical outcomes in Japanese incident dialysis patients: a prospective observational multicenter study. Clin Exp Nephrol. 2022;26(5):466-475.
  16. Muto R, Kato S, Lindholm B, Qureshi AR, Ishimoto T, Kosugi T, Maruyama S. Increased Monocyte/Lymphocyte Ratio as Risk Marker for Cardiovascular Events and Infectious Disease Hospitalization in Dialysis Patients. Blood Purif. 2022;51(9):747-755.
  17. Nagano F, Mizuno T, Imai M, Takahashi K, Tsuboi N, Maruyama S, Mizuno M. Expression of a Crry/p65 is reduced in acute lung injury induced by extracellular histones. FEBS Open Bio. 2022;12(1):192-202.
  18. Morooka H, Tanaka A, Kasugai D, Ozaki M, Numaguchi A, Maruyama S. Abnormal magnesium levels and their impact on death and acute kidney injury in critically ill children. Pediatr Nephrol. 2022;37(5):1157-1165.
2021
  1. Saito R, Hirayama A, Akiba A, Kamei Y, Kato Y, Ikeda S, Kwan B, Pu M, Natarajan L, Shinjo H, Akiyama S, Tomita M, Soga T, Maruyama S. Urinary Metabolome Analyses of Patients with Acute Kidney Injury Using Capillary Electrophoresis-Mass Spectrometry. Metabolites. 2021;11(10):671.
  2. Ryuge A, Kosugi T, Maeda K, Banno R, Gou Y, Zaitsu K, Ito T, Sato Y, Hirayama A, Tsubota S, Honda T, Nakajima K, Ozaki T, Kondoh K, Takahashi K, Kato N, Ishimoto T, Soga T, Nakagawa T, Koike T, Arima H, Yuzawa Y, Minokoshi Y, Maruyama S, Kadomatsu K. Basigin deficiency prevents anaplerosis and ameliorates insulin resistance and hepatosteatosis. JCI Insight. 2021;6(20):e142464.
  3. Hashimoto Y, Imaizumi T, Kato S, Yasuda Y, Ishimoto T, Kawashiri H, Hori A, Maruyama S. Effect of body mass index on the association between alcohol consumption and the development of chronic kidney disease. Sci Rep. 2021;11(1):20440.
  4. Kurasawa S, Hishida M, Imaizumi T, Okazaki M, Nishibori N, Kondo T, Kasuga H, Maruyama S. All-cause and cardiovascular mortality in patients undergoing hemodialysis with aortic sclerosis and mild-to-moderate aortic stenosis: A cohort study. Atherosclerosis. 2021;331:12-19.
  5. Hori M, Yasuda K, Takahashi H, Yamazaki C, Morozumi K, Maruyama S. Impact of serum magnesium and bone mineral density on systemic fractures in chronic hemodialysis patients. PLoS One. 2021;16(5):e0251912.
  6. Morooka H, Yamamoto J, Tanaka A, Inaguma D, Maruyama S. Relationship between mortality and use of sodium bicarbonate at the time of dialysis initiation: a prospective observational study. BMC Nephrol. 2021;22(1):118.
  7. Hachiya A, Karasawa M, Imaizumi T, Kato N, Katsuno T, Ishimoto T, Kosugi T, Tsuboi N, Maruyama S. The ISN/RPS 2016 classification predicts renal prognosis in patients with first-onset class III/IV lupus nephritis. Sci Rep. 2021;11(1):1525.
  8. Ozeki T, Nagata M, Katsuno T, Inagaki K, Goto K, Kato S, Yasuda Y, Tsuboi N, Maruyama S. Nephrotic syndrome with focal segmental glomerular lesions unclassified by Columbia classification; Pathology and clinical implication. PLoS One. 2021;16(1):e0244677.
  9. Kikuchi K, Imaizumi T, Ando M, Kato S, Kondo T, Honda H, Yoshida Y, Maruyama S. Validity of \\\"One-size-fits-all\\\" Approaches for the National Health Screening and Education Program: A Large-scale Cohort Study of Corporate Insurance Beneficiaries. Intern Med. 2021;60(11):1681-1689.
2020
  1. Itano Y, Kato S, Tsuboi M, Kasuga H, Tsuruta Y, Sato F, Hishida M, Ishimoto T, Kosugi T, Ando M, Kuwatsuka Y, Maruyama S. A Prospective, Randomized Clinical Trial of Etelcalcetide in Patients Receiving Hemodialysis With Secondary Hyperparathyroidism (the DUET Trial). Kidney Int Rep. 2020;5(12):2168-2177.
  2. Morooka H, Tanaka A, Inaguma D, Maruyama S. Peripheral artery disease at the time of dialysis initiation and mortality: a prospective observational multicenter study. BMJ Open. 2020;10(12):e042315.
  3. Morooka H, Kasugai D, Tanaka A, Ozaki M, Numaguchi A, Maruyama S. Prognostic Impact of Parameters of Metabolic Acidosis in Critically Ill Children with Acute Kidney Injury: A Retrospective Observational Analysis Using the PIC Database. Diagnostics (Basel). 2020;10(11):937.
  4. Itano Y, Sobajima H, Ohashi N, Shibata T, Fujiya A, Nagata T, Ando M, Imaizumi T, Kubo Y, Ozeki T, Katsuno T, Kato S, Yasuda Y, Maruyama S. High urinary glucose is associated with improved renal prognosis in patients with diabetes mellitus. J Diabetes Investig. 2020. Epub ahead of print.
  5. Ryuge A, Saito S, Morioka H, Hachiya A, Kato N, Ishimoto T, Kosugi T, Maruyama S. Acquired Fanconi Syndrome in a Patient with Nontyphoidal Salmonella Bacteremia. Intern Med. 2021;60(5):761-764.
  6. Imaizumi T, Nakatochi M, Fujita Y, Yamamoto R, Watanabe K, Maekawa M, Yamawaka T, Katsuno T, Maruyama S. Glucocorticoid treatment is associated with ICU-acquired hypernatremia: a nested case-control study. Clin Exp Nephrol. 2021;25(2):131-139.
  7. Koshi E, Saito S, Okazaki M, Toyama Y, Ishimoto T, Kosugi T, Hiraiwa H, Jingushi N, Yamamoto T, Ozaki M, Goto Y, Numaguchi A, Miyagawa Y, Kato I, Tetsuka N, Yagi T, Maruyama S. Efficacy of favipiravir for an end stage renal disease patient on maintenance hemodialysis infected with novel coronavirus disease 2019. CEN Case Rep. 2021;10(1):126-131.
  8. Hishida M, Imaizumi T, Menez S, Okazaki M, Akiyama S, Kasuga H, Ishigami J, Maruyama S, Matsushita K. Additional prognostic value of toe-brachial index beyond ankle-brachial index in hemodialysis patients. BMC Nephrol. 2020;21(1):353.
  9. Ozeki T, Maruyama S, Nagata M, Shimizu A, Sugiyama H, Sato H, Yokoyama H; Committee for Renal Biopsy and Disease Registry of the Japanese Society of Nephrology. The revised version 2018 of the nationwide web-based registry system for kidney diseases in Japan: Japan Renal Biopsy Registry and Japan Kidney Disease Registry. Clin Exp Nephrol. 2020;24(11):1058-1068.
  10. Okazaki M, Inaguma D, Imaizumi T, Hishida M, Kurasawa S, Kubo Y, Kato S, Yasuda Y, Katsuno T, Kaneda F, Maruyama S. Impact of old age on the association between in-center extended-hours hemodialysis and mortality in patients on incident hemodialysis. PLoS One. 2020;15(7):e0235900.
  11. Yokoe Y, Tsuboi N, Imaizumi T, Kitagawa A, Karasawa M, Ozeki T, Endo N, Sawa Y, Kato S, Katsuno T, Maruyama S, Yamagata K, Usui J, Nagata M, Sada KE, Sugiyama H, Amano K, Arimura Y, Atsumi T, Yuzawa Y, Dobashi H, Takasaki Y, Harigai M, Hasegawa H, Makino H, Matsuo S. Clinical impact of urinary CD11b and CD163 on the renal outcomes of anti-neutrophil cytoplasmic antibody-associated glomerulonephritis. Nephrol Dial Transplant. 2020:gfaa097.
  12. Suzuki Y, Mizuno M, Sakata F, Kojima H, Sato Y, Kishimoto M, Suzuki N, Kinashi H, Saito S, Katsuno T, Kosugi T, Maruyama S, Murata M, Kiyoi H, Ito Y. Successful Introduction of Peritoneal Dialysis in an End-stage Renal Failure Patient with Idiopathic Aplastic Anemia. Intern Med. 2020;59(5):683-687.
  13. Kato S, Ando M, Honda H, Yoshida Y, Imaizumi T, Yamamoto N, Maruyama S. Effectiveness of Lifestyle Intervention Using the Internet of Things System for Individuals with Early Type 2 Diabetes Mellitus. Intern Med. 2020;59(1):45-53.
  14. Kato S, Lindholm B, Qureshi AR, Mukai H, Yuzawa Y, Maruyama S. Inter-leg systolic blood pressure difference predicts cardiovascular events and mortality in incident hemodialysis patients. Int J Artif Organs. 2020;43(4):217-224.
2019
  1. Hishida M, Imaizumi T, Nishiyama T, Okazaki M, Kato S, Kubo Y, Ando M, Kaneda H, Maruyama S. Survival Benefit of Maintained or Increased Body Mass Index in Patients Undergoing Extended-Hours Hemodialysis Without Dietary Restrictions. J Ren Nutr. 2020;30(2):154-162.
  2. Sato Y, Roncal-Jimenez CA, Andres-Hernando A, Jensen T, Tolan DR, Sanchez- Lozada LG, Newman LS, Butler-Dawson J, Sorensen C, Glaser J, Miyazaki M, Diaz HF, Ishimoto T, Kosugi T, Maruyama S, Garcia GE, Lanaspa MA, Johnson RJ. Increase of core temperature affected the progression of kidney injury by repeated heat stress exposure. Am J Physiol Renal Physiol. 2019;317(5):F1111-F1121.
  3. Hayasaki T, Ishimoto T, Doke T, Hirayama A, Soga T, Furuhashi K, Kato N, Kosugi T, Tsuboi N, Lanaspa MA, Johnson RJ, Maruyama S, Kadomatsu K. Fructose increases the activity of sodium hydrogen exchanger in renal proximal tubules that is dependent on ketohexokinase. J Nutr Biochem. 2019;71:54-62.
  4. Akiyama S, Imai E, Maruyama S. Immunology of membranous nephropathy. F1000Res. 2019;8:F1000 Faculty Rev-734.
  5. Yoshioka T, Kosugi T, Masuda T, Watanabe T, Ryuge A, Nagaya H, Maeda K, Sato Y, Katsuno T, Kato N, Ishimoto T, Yuzawa Y, Maruyama S, Kadomatsu K. CD147/Basigin Deficiency Prevents the Development of Podocyte Injury through FAK Signaling. Am J Pathol. 2019;189(7):1338-1350.
  6. Yasuda Y, Imaizumi T, Inagaki K, Ozeki T, Hishida M, Katsuno T, Tsuboi N, Maruyama S. Clinical impact of endocapillary proliferation with modified cutoff points in IgA nephropathy patients. PLoS One. 2019;14(3):e0214414.
  7. Sun T, Sakata F, Ishii T, Tawada M, Suzuki Y, Kinashi H, Katsuno T, Takei Y, Maruyama S, Mizuno M, Ito Y. Excessive salt intake increases peritoneal solute transport rate via local tonicity-responsive enhancer binding protein in subtotal nephrectomized mice. Nephrol Dial Transplant. 2019;34(12):2031-2042.
  8. Kitagawa A, Tsuboi N, Yokoe Y, Katsuno T, Ikeuchi H, Kajiyama H, Endo N, Sawa Y, Suwa J, Sugiyama Y, Hachiya A, Mimura T, Hiromura K, Maruyama S. Urinary levels of the leukocyte surface molecule CD11b associate with glomerular inflammation in lupus nephritis. Kidney Int. 2019;95(3):680-692.
  9. Funahashi Y, Kato N, Masuda T, Nishio F, Kitai H, Ishimoto T, Kosugi T, Tsuboi N, Matsuda N, Maruyama S, Kadomatsu K. miR-146a targeted to splenic macrophages prevents sepsis-induced multiple organ injury. Lab Invest. 2019;99(8):1130-1142.
  10. Shigemoto E, Mizuno M, Suzuki Y, Kobayashi K, Sakata F, Kariya T, Katsuno T, Maruyama S, Ito Y. Increase of Eosinophil in Dialysate During Induction of Peritoneal Dialysis. Perit Dial Int. 2019;39(1):90-92.
  11. Tsujita M, Kosugi T, Goto N, Futamura K, Nishihira M, Okada M, Hiramitsu T, Narumi S, Uchida K, Takeda A, Morozumi K, Maruyama S, Watarai Y. The effect of maintaining high hemoglobin levels on long-term kidney function in kidney transplant recipients: a randomized controlled trial. Nephrol Dial Transplant. 2019;34(8):1409-1416.
  12. Ozeki T, Katsuno T, Hayashi H, Kato S, Yasuda Y, Ando M, Tsuboi N, Hagiwara D, Arima H, Maruyama S. Short-Term Steroid Regimen for Adult Steroid-Sensitive Minimal Change Disease. Am J Nephrol. 2019;49(1):54-63.
  13. Tawada M, Hamada C, Suzuki Y, Sakata F, Sun T, Kinashi H, Katsuno T, Takei Y, Maruyama S, Honda K, Mizuno M, Ito Y. Effects of long-term treatment with low-GDP, pH-neutral solutions on peritoneal membranes in peritoneal dialysis patients. Clin Exp Nephrol. 2019;23(5):689-699.
2018
  1. Iguchi D, Mizuno M, Suzuki Y, Sakata F, Maruyama S, Okada A, Okada H, Ito Y. Anti-C5a complementary peptide mitigates zymosan-induced severe peritonitis with fibrotic encapsulation in rats pretreated with methylglyoxal. Am J Physiol Renal Physiol. 2018;315(6):F1732-F1746.
  2. Katsuno T, Masuda T, Saito S, Kato N, Ishimoto T, Kato S, Kosugi T, Tsuboi N, Kitamura H, Tsuzuki T, Ito Y, Maruyama S. Therapeutic efficacy of rituximab for the management of adult-onset steroid-dependent nephrotic syndrome: a retrospective study. Clin Exp Nephrol. 2019 ;23(2):207-214.
  3. Yamaguchi M, Ando M, Katsuno T, Tsuboi N, Maruyama S. Urinary protein and renal prognosis in idiopathic membranous nephropathy: a multicenter retrospective cohort study in Japan. Ren Fail. 2018;40(1):435-441.
  4. Maeda K, Otomo K, Yoshida N, Abu-Asab MS, Ichinose K, Nishino T, Kono M, Ferretti A, Bhargava R, Maruyama S, Bickerton S, Fahmy TM, Tsokos MG, Tsokos GC. CaMK4 compromises podocyte function in autoimmune and nonautoimmune kidney disease. J Clin Invest. 2018;128(8):3445-3459.
  5. Kato S, Ando M, Kondo T, Yoshida Y, Honda H, Maruyama S. Lifestyle intervention using Internet of Things (IoT) for the elderly: A study protocol for a randomized control trial (the BEST-LIFE study). Nagoya J Med Sci. 2018;80(2):175-182.
  6. Ozeki T, Ando M, Yamaguchi M, Katsuno T, Kato S, Yasuda Y, Tsuboi N, Maruyama S. Treatment patterns and steroid dose for adult minimal change disease relapses: A retrospective cohort study. PLoS One. 20188;13(6):e0199228.
  7. Yamaguchi M, Ando M, Katsuno T, Tsuboi N, Maruyama S. Smoking Is a Risk Factor for Relapse of Antimyeloperoxidase Antibodies-Associated Vasculitis. J Clin Rheumatol. 2018;24(7):361-367.
  8. Doke T, Ishimoto T, Hayasaki T, Ikeda S, Hasebe M, Hirayama A, Soga T, Kato N, Kosugi T, Tsuboi N, Lanaspa MA, Johnson RJ, Kadomatsu K, Maruyama S. Lacking ketohexokinase-A exacerbates renal injury in streptozotocin-induced diabetic mice. Metabolism. 2018;85:161-170.
  9. Okazaki M, Inaguma D, Imaizumi T, Kada A, Yaomura T, Tsuboi N, Maruyama S. Unfavorable effects of history of volume overload and late referral to a nephrologist on mortality in patients initiating dialysis: a multicenter prospective cohort study in Japan. BMC Nephrol. 2018;19(1):65.
  10. Mori Y, Masuda T, Kosugi T, Yoshioka T, Hori M, Nagaya H, Maeda K, Sato Y, Kojima H, Kato N, Ishimoto T, Katsuno T, Yuzawa Y, Kadomatsu K, Maruyama S. The clinical relevance of plasma CD147/basigin in biopsy-proven kidney diseases. Clin Exp Nephrol. 2018;22(4):815-824.
  11. Inagaki K, Yasuda Y, Ando M, Hachiya A, Ozeki T, Hishida M, Imaizumi T, Katsuno T, Kato S, Tsuboi N, Maruyama S. Seasonal proteinuria changes in IgA nephropathy patients after proteinuria remission. PLoS One. 2017;12(11):e0187607.
  12. Mizukoshi T, Kato S, Ando M, Sobajima H, Ohashi N, Naruse T, Saka Y, Shimizu H, Nagata T, Maruyama S. Renoprotective effects of topiroxostat for Hyperuricaemic patients with overt diabetic nephropathy study (ETUDE study): A prospective, randomized, multicentre clinical trial. Nephrology (Carlton). 2018;23(11):1023-1030.
  13. Kariya T, Nishimura H, Mizuno M, Suzuki Y, Matsukawa Y, Sakata F, Maruyama S, Takei Y, Ito Y. TGF-β1-VEGF-A pathway induces neoangiogenesis with peritoneal fibrosis in patients undergoing peritoneal dialysis. Am J Physiol Renal Physiol. 2018;314(2):F167-F180.
2017
  1. Imaizumi T, Nakatochi M, Fujita Y, Nomura R, Watanabe K, Maekawa M, Yamakawa T, Katsuno T, Maruyama S. The association between intensive care unit- acquired hypernatraemia and mortality in critically ill patients with cerebrovascular diseases: a single-centre cohort study in Japan. BMJ Open. 2017;7(8):e016248.
  2. Katsuno T, Mizuno S, Mabuchi M, Tsuboi N, Komatsuda A, Maruyama S. Long- term renal survival of γ3-heavy chain deposition disease: a case report. BMC Nephrol. 2017;18(1):239.
  3. Katsuno T, Ozaki T, Kim H, Kato N, Suzuki Y, Akiyama S, Ishimoto T, Kosugi T, Tsuboi N, Ito Y, Maruyama S. Single-dose Rituximab Therapy for Refractory Idiopathic Membranous Nephropathy: A Single-center Experience. Intern Med. 2017;56(13):1679-1686.
  4. Yasuda Y, Katsuno T, Kato S, Imaizumi T, Ozeki T, Hishida M, Nagata T, Ando M, Tsuboi N, Maruyama S. The Japanese Histologic Classification and T-score in the Oxford Classification system could predict renal outcome in Japanese IgA nephropathy patients. Clin Exp Nephrol. 2017;21(6):986-994.
  5. Masuda T, Maeda K, Sato W, Kosugi T, Sato Y, Kojima H, Kato N, Ishimoto T, Tsuboi N, Uchimura K, Yuzawa Y, Maruyama S, Kadomatsu K. Growth Factor Midkine Promotes T-Cell Activation through Nuclear Factor of Activated T Cells Signaling and Th1 Cell Differentiation in Lupus Nephritis. Am J Pathol. 2017;187(4):740-751.
  6. Yamaguchi M, Hori M, Hiroshi N, Maruyama S. Postpartum atypical hemolytic uremic syndrome with complement factor H mutation complicated by reversible cerebrovascular constriction syndrome successfully treated with eculizumab. Thromb Res. 2017;151:79-81.
  7. Sakata F, Ito Y, Mizuno M, Sawai A, Suzuki Y, Tomita T, Tawada M, Tanaka A, Hirayama A, Sagara A, Wada T, Maruyama S, Soga T, Matsuo S, Imai E, Takei Y. Sodium chloride promotes tissue inflammation via osmotic stimuli in subtotal- nephrectomized mice. Lab Invest. 2017;97(4):432-446.
  8. Mizuno M, Suzuki Y, Higashide K, Sei Y, Iguchi D, Sakata F, Horie M, Maruyama S, Matsuo S, Morgan BP, Ito Y. High Levels of Soluble C5b-9 Complex in Dialysis Fluid May Predict Poor Prognosis in Peritonitis in Peritoneal Dialysis Patients. PLoS One. 2017;12(1):e0169111.
2016
  1. Ryuge A, Ito Y, Yamakawa T, Tanaka H, Yasui H, Mashimo S, Watanabe K, Nomura R, Suganuma N, Maruyama S. Fanconi Syndrome Associated with Hyponatremia in Two Patients with Legionella Pneumonia. Intern Med. 2016;55(23):3479-3484.
  2. Du Q, Tsuboi N, Shi Y, Ito S, Sugiyama Y, Furuhashi K, Endo N, Kim H, Katsuno T, Akiyama S, Matsuo S, Isobe KI, Maruyama S. Transfusion of CD206+ M2 Macrophages Ameliorates Antibody-Mediated Glomerulonephritis in Mice. Am J Pathol. 2016;186(12):3176-3188.
  3. Yashima A, Mizuno M, Yuzawa Y, Shimada K, Suzuki N, Tawada H, Sato W, Tsuboi N, Maruyama S, Ito Y, Matsuo S, Ohno T. Mesangial proliferative glomerulonephritis in murine malaria parasite, Plasmodium chabaudi AS, infected NC mice. Clin Exp Nephrol. 2017;21(4):589-596.
  4. Kato H, Nangaku M, Hataya H, Sawai T, Ashida A, Fujimaru R, Hidaka Y, Kaname S, Maruyama S, Yasuda T, Yoshida Y, Ito S, Hattori M, Miyakawa Y, Fujimura Y, Okada H, Kagami S, Joint Committee for the Revision of Clinical Guides of Atypical Hemolytic Uremic Syndrome in J. Clinical guides for atypical hemolytic uremic syndrome in Japan. Pediatr Int, 2016; 58: 549-555.
  5. Kato S, Ando M, Mizukoshi T, Nagata T, Katsuno T, Kosugi T, Tsuboi N, Maruyama S. Randomized control trial for the assessment of the anti-albuminuric effects of topiroxostat in hyperuricemic patients with diabetic nephropathy (the ETUDE study). Nagoya J Med Sci, 2016; 78: 135-142.
  6. Kato S, Shiels PG, McGuinness D, Lindholm B, Stenvinkel P, Nordfors L, Qureshi AR, Yuzawa Y, Matsuo S, Maruyama S. Telomere Attrition and Elongation after Chronic Dialysis Initiation in Patients with End-Stage Renal Disease. Blood Purif, 2016; 41: 25-33.
  7. Kubota K, Hoshino J, Ueno T, Mise K, Hazue R, Sekine A, Yabuuchi J, Yamanouchi M, Suwabe T, Kikuchi K, Sumida K, Hayami N, Sawa N, Takaichi K, Fujii T, Ohashi K, Akiyama S, Maruyama S, Ubara Y. Phospholipase A2 Receptor-Positive Idiopathic Membranous Glomerulonephritis with Onset at 95 Years: Case Report. Case Rep Nephrol Dial, 2016; 6: 76-82.
  8. Maeda K, Enomoto A, Hara A, Asai N, Kobayashi T, Horinouchi A, Maruyama S, Ishikawa Y, Nishiyama T, Kiyoi H, Kato T, Ando K, Weng L, Mii S, Asai M, Mizutani Y, Watanabe O, Hirooka Y, Goto H, Takahashi M. Identification of Meflin as a Potential Marker for Mesenchymal Stromal Cells. Sci Rep, 2016; 6: 22288.
  9. Mizuno M, Ito Y, Suzuki Y, Sakata F, Saka Y, Hiramatsu T, Tamai H, Mizutani M, Naruse T, Ohashi N, Kasuga H, Shimizu H, Kurata H, Kurata K, Suzuki S, Kido S, Tsuruta Y, Matsuoka T, Horie M, Maruyama S, Matsuo S. Recent analysis of status and outcomes of peritoneal dialysis in the Tokai area of Japan: the second report of the Tokai peritoneal dialysis registry. Clin Exp Nephrol, 2016.
  10. Nagata T, Sobajima H, Ohashi N, Hirakawa A, Katsuno T, Yasuda Y, Matsuo S, Tsuboi N, Maruyama S. Association between 24h Urinary Sodium and Potassium Excretion and Estimated Glomerular Filtration Rate (eGFR) Decline or Death in Patients with Diabetes Mellitus and eGFR More than 30 ml/min/1.73m2. PLoS One, 2016; 11: e0152306.
  11. Sawai A, Yasuda Y, Suzuki S, Ishii H, Goto M, Kato S, Hayashi M, Maruyama S, Murohara T, Oiso Y, Matsuo S. Impact of non-invasive cardiovascular screening programs as a predictor of cardiovascular events among asymptomatic chronic kidney disease patients. Clin Exp Nephrol, 2016; 20: 416-424.
  12. Takayama Y, Yasuda Y, Suzuki S, Shibata Y, Tatami Y, Shibata K, Niwa M, Sawai A, Morimoto R, Kato S, Ishii H, Maruyama S, Murohara T. Relationship between abdominal aortic and coronary artery calcification as detected by computed tomography in chronic kidney disease patients. Heart Vessels, 2016; 31: 1030-1037.
  13. Tawada M, Ito Y, Hamada C, Honda K, Mizuno M, Suzuki Y, Sakata F, Terabayashi T, Matsukawa Y, Maruyama S, Imai E, Matsuo S, Takei Y. Vascular Endothelial Cell Injury Is an Important Factor in the Development of Encapsulating Peritoneal Sclerosis in Long-Term Peritoneal Dialysis Patients. PLoS One, 2016; 11: e0154644.
  14. Asano S, Mizuno S, Okachi S, Aso H, Wakahara K, Hashimoto N, Ito S, Kozaki Y, Katsuno T, Maruyama S, Hasegawa Y. Antineutrophil Cytoplasmic Antibody-associated Vasculitis Superimposed on Infection-related Glomerulonephritis Secondary to Pulmonary Mycobacterium avium Complex Infection. Intern Med, 2016; 55: 2439-2445.
  15. Endo N, Tsuboi N, Furuhashi K, Shi Y, Du Q, Abe T, Hori M, Imaizumi T, Kim H, Katsuno T, Ozaki T, Kosugi T, Matsuo S, Maruyama S. Urinary soluble CD163 level reflects glomerular inflammation in human lupus nephritis. Nephrol Dial Transplant, 2016.
  16. Hamada M, Yasuda Y, Kato S, Arafuka H, Goto M, Hayashi M, Kajita E, Maruyama S. The effectiveness and safety of modest exercise in Japanese patients with chronic kidney disease: a single-armed interventional study. Clin Exp Nephrol, 2016; 20: 204-211.
  17. Hattori M, Iwano M, Sako M, Honda M, Okada H, Akioka Y, Ashida A, Kawasaki Y, Kiyomoto H, Terada Y, Hirano D, Fujieda M, Fujimoto S, Masaki T, Maruyama S, Mastuo S. Transition of adolescent and young adult patients with childhood-onset chronic kidney disease from pediatric to adult renal services: a nationwide survey in Japan. Clin Exp Nephrol, 2016.
  18. Hayashi H, Sato W, Kosugi T, Nishimura K, Sugiyama D, Asano N, Ikematsu S, Komori K, Nishiwaki K, Kadomatsu K, Matsuo S, Maruyama S, Yuzawa Y. Efficacy of urinary midkine as a biomarker in patients with acute kidney injury. Clin Exp Nephrol, 2016.
  19. Hishida M, Tamai H, Morinaga T, Maekawa M, Aoki T, Tomida H, Komatsu S, Kamiya T, Maruyama S, Matsuo S, Inaguma D. Aichi cohort study of the prognosis in patients newly initiated into dialysis (AICOPP): baseline characteristics and trends observed in diabetic nephropathy. Clin Exp Nephrol, 2016; 20: 795-807.
  20. Imai E, Maruyama S, Nangaku M, Hirakata H, Hayashi T, Narita I, Kono H, Nakatani E, Morita S, Tsubakihara Y, Akizawa T. Rationale and study design of a randomized controlled trial to assess the effects of maintaining hemoglobin levels using darbepoetin alfa on prevention of development of end-stage kidney disease in non-diabetic CKD patients (PREDICT Trial). Clin Exp Nephrol, 2016; 20: 71-76.
  21. Imaizumi T, Ando M, Nakatochi M, Maruyama S, Yasuda Y, Honda H, Kuwatsuka Y, Kato S, Kondo T, Iwata M, Nakashima T, Yasui H, Takamatsu H, Okajima H, Yoshida Y, Matsuo S. Association of interactions between dietary salt consumption and hypertension-susceptibility genetic polymorphisms with blood pressure among Japanese male workers. Clin Exp Nephrol, 2016.
  22. Imaizumi T, Ando M, Nakatochi M, Yasuda Y, Honda H, Kuwatsuka Y, Kato S, Kondo T, Iwata M, Nakashima T, Yasui H, Takamatsu H, Okajima H, Yoshida Y, Maruyama S. Effect of dietary energy and polymorphisms in BRAP and GHRL on obesity and metabolic traits. Obes Res Clin Pract, 2016.
  23. Imaizumi T, Nakatochi M, Akiyama S, Yamaguchi M, Kurosawa H, Hirayama Y, Katsuno T, Tsuboi N, Hara M, Maruyama S. Urinary Podocalyxin as a Biomarker to Diagnose Membranous Nephropathy. PLoS One, 2016; 11: e0163507.
2015
  1. Yokoyama H, Sugiyama H, Narita I, Saito T, Yamagata K, Nishio S, Fujimoto S, Mori N, Yuzawa Y, Okuda S, Maruyama S, Sato H, Ueda Y, Makino H, Matsuo S. Outcomes of primary nephrotic syndrome in elderly Japanese: retrospective analysis of the Japan Renal Biopsy Registry (J-RBR). Clin Exp Nephrol, 2015; 19: 496-505.
  2. Yamaguchi M, Ando M, Kato S, Katsuno T, Kato N, Kosugi T, Sato W, Tsuboi N, Yasuda Y, Mizuno M, Ito Y, Matsuo S, Maruyama S. Increase of Antimyeloperoxidase Antineutrophil Cytoplasmic Antibody (ANCA) in Patients with Renal ANCA-associated Vasculitis: Association with Risk to Relapse. J Rheumatol, 2015; 42: 1853-1860.
  3. Terabayashi T, Ito Y, Mizuno M, Suzuki Y, Kinashi H, Sakata F, Tomita T, Iguchi D, Tawada M, Nishio R, Maruyama S, Imai E, Matsuo S, Takei Y. Vascular endothelial growth factor receptor-3 is a novel target to improve net ultrafiltration in methylglyoxal-induced peritoneal injury. Lab Invest, 2015; 95: 1029-1043.
  4. Tatami Y, Yasuda Y, Suzuki S, Ishii H, Sawai A, Shibata Y, Ota T, Shibata K, Niwa M, Morimoto R, Hayashi M, Kato S, Maruyama S, Murohara T. Impact of abdominal aortic calcification on long-term cardiovascular outcomes in patients with chronic kidney disease. Atherosclerosis, 2015; 243: 349-355.
  5. Shimbo Y, Suzuki S, Ishii H, Shibata Y, Tatami Y, Harata S, Osugi N, Ota T, Tanaka A, Shibata K, Mizukoshi T, Yasuda Y, Maruyama S, Murohara T. Association of Estimated Glomerular Filtration Rate and Proteinuria With Lipid-Rich Plaque in Coronary Artery Disease. Circ J, 2015; 79: 2263-2270.
  6. Shibata K, Yasuda Y, Kobayashi R, Ando Y, Shimokata T, Kamiya H, Hayashi M, Maruyama S, Matsuo S, Nakao M, Tsuchiya T, Teramachi H. Renal function evaluation in patients with cancer who were scheduled to receive carboplatin or S-1. Clin Exp Nephrol, 2015; 19: 1107-1113.
  7. Sei Y, Mizuno M, Suzuki Y, Imai M, Higashide K, Harris CL, Sakata F, Iguchi D, Fujiwara M, Kodera Y, Maruyama S, Matsuo S, Ito Y. Expression of membrane complement regulators, CD46, CD55 and CD59, in mesothelial cells of patients on peritoneal dialysis therapy. Mol Immunol, 2015; 65: 302-309.
  8. Sato Y, Sato W, Maruyama S, Wilcox CS, Falck JR, Masuda T, Kosugi T, Kojima H, Maeda K, Furuhashi K, Ando M, Imai E, Matsuo S, Kadomatsu K. Midkine Regulates BP through Cytochrome P450-Derived Eicosanoids. J Am Soc Nephrol, 2015; 26: 1806-1815.
  9. Saka Y, Ito Y, Iida Y, Maruyama S, Matsuo S. Efficacy and safety of fluoroscopic manipulation using the alpha-replacer for peritoneal catheter malposition. Clin Exp Nephrol, 2015; 19: 521-526.
  10. Nakatochi M, Ushida Y, Yasuda Y, Yoshida Y, Kawai S, Kato R, Nakashima T, Iwata M, Kuwatsuka Y, Ando M, Hamajima N, Kondo T, Oda H, Hayashi M, Kato S, Yamaguchi M, Maruyama S, Matsuo S, Honda H. Identification of an interaction between VWF rs7965413 and platelet count as a novel risk marker for metabolic syndrome: an extensive search of candidate polymorphisms in a case-control study. PLoS One, 2015; 10: e0117591.
  11. Nagata T, Yasuda Y, Ando M, Abe T, Katsuno T, Kato S, Tsuboi N, Matsuo S, Maruyama S. Clinical impact of kidney function on presepsin levels. PLoS One, 2015; 10: e0129159.
  12. Maeda K, Kosugi T, Sato W, Kojima H, Sato Y, Kamimura D, Kato N, Tsuboi N, Yuzawa Y, Matsuo S, Murakami M, Maruyama S, Kadomatsu K. CD147/basigin limits lupus nephritis and Th17 cell differentiation in mice by inhibiting the interleukin-6/STAT-3 pathway. Arthritis Rheumatol, 2015; 67: 2185-2195.
  13. Kosugi T, Maeda K, Sato W, Maruyama S, Kadomatsu K. CD147 (EMMPRIN/Basigin) in kidney diseases: from an inflammation and immune system viewpoint. Nephrol Dial Transplant, 2015; 30: 1097-1103.
  14. Kato S, Maruyama S, Makino H, Wada J, Ogawa D, Uzu T, Araki H, Koya D, Kanasaki K, Oiso Y, Goto M, Nishiyama A, Kobori H, Imai E, Ando M, Matsuo S. Anti-albuminuric effects of spironolactone in patients with type 2 diabetic nephropathy: a multicenter, randomized clinical trial. Clin Exp Nephrol, 2015; 19: 1098-1106.
  15. Hayashi N, Akiyama S, Okuyama H, Matsui Y, Adachi H, Yamaya H, Maruyama S, Imai E, Matsuo S, Yokoyama H. Clinicopathological characteristics of M-type phospholipase A2 receptor (PLA2R)-related membranous nephropathy in Japanese. Clin Exp Nephrol, 2015; 19: 797-803.
  16. Hattori Y, Kim H, Tsuboi N, Yamamoto A, Akiyama S, Shi Y, Katsuno T, Kosugi T, Ueda M, Matsuo S, Maruyama S. Therapeutic Potential of Stem Cells from Human Exfoliated Deciduous Teeth in Models of Acute Kidney Injury. PLoS One, 2015; 10: e0140121.
  17. Baba M, Shimbo T, Horio M, Ando M, Yasuda Y, Komatsu Y, Masuda K, Matsuo S, Maruyama S. Longitudinal Study of the Decline in Renal Function in Healthy Subjects. PLoS One, 2015; 10: e0129036.
  18. Akiyama S, Akiyama M, Imai E, Ozaki T, Matsuo S, Maruyama S. Prevalence of anti-phospholipase A2 receptor antibodies in Japanese patients with membranous nephropathy. Clin Exp Nephrol, 2015; 19: 653-660.
  19. Abe T, Kato S, Tsuruta Y, Sugiura S, Katsuno T, Kosugi T, Tsuboi N, Matsuo S, Maruyama S. Neutrophil/lymphocyte ratio as a predictor of cardiovascular events in incident dialysis patients: a Japanese prospective cohort study. Clin Exp Nephrol, 2015; 19: 718-724.
2014
  1. Yamaguchi M, Yoshioka T, Yamakawa T, Maeda M, Shimizu H, Fujita Y, Maruyama S, Ito Y, Matsuo S. Anti-neutrophil cytoplasmic antibody-associated vasculitis associated with infectious mononucleosis due to primary Epstein-Barr virus infection: report of three cases. Clin Kidney J, 2014; 7: 45-48.
  2. Yamaguchi M, Ando M, Yamamoto R, Akiyama S, Kato S, Katsuno T, Kosugi T, Sato W, Tsuboi N, Yasuda Y, Mizuno M, Ito Y, Matsuo S, Maruyama S. Smoking is a risk factor for the progression of idiopathic membranous nephropathy. PLoS One, 2014; 9: e100835.
  3. Yamaguchi M, Ando M, Yamamoto R, Akiyama S, Kato S, Katsuno T, Kosugi T, Sato W, Tsuboi N, Yasuda Y, Mizuno M, Ito Y, Matsuo S, Maruyama S. Patient age and the prognosis of idiopathic membranous nephropathy. PLoS One, 2014; 9: e110376.
  4. Wada T, Nangaku M, Maruyama S, Imai E, Shoji K, Kato S, Endo T, Muso E, Kamata K, Yokoyama H, Fujimoto K, Obata Y, Nishino T, Kato H, Uchida S, Sasatomi Y, Saito T, Matsuo S. A multicenter cross-sectional study of circulating soluble urokinase receptor in Japanese patients with glomerular disease. Kidney Int, 2014; 85: 641-648.
  5. Tsuboi N, Maruyama S, Matsuo S, Imai E. A ray of light in the dark: alternative approaches to the assessment and treatment of ischemic nephropathy. Nephrol Dial Transplant, 2014; 29: 228-231.
  6. Takahashi H, Ito Y, Ishii H, Aoyama T, Kamoi D, Kasuga H, Yasuda K, Maruyama S, Matsuo S, Murohara T, Yuzawa Y. Geriatric nutritional risk index accurately predicts cardiovascular mortality in incident hemodialysis patients. J Cardiol, 2014; 64: 32-36.
  7. Shinjo H, Sato W, Imai E, Kosugi T, Hayashi H, Nishimura K, Nishiwaki K, Yuzawa Y, Matsuo S, Maruyama S. Comparison of kidney disease: improving global outcomes and acute kidney injury network criteria for assessing patients in intensive care units. Clin Exp Nephrol, 2014; 18: 737-745.
  8. Shi Y, Tsuboi N, Furuhashi K, Du Q, Horinouchi A, Maeda K, Kosugi T, Matsuo S, Maruyama S. Pristane-induced granulocyte recruitment promotes phenotypic conversion of macrophages and protects against diffuse pulmonary hemorrhage in Mac-1 deficiency. J Immunol, 2014; 193: 5129-5139.
  9. Nagaya H, Kosugi T, Maeda-Hori M, Maeda K, Sato Y, Kojima H, Hayashi H, Kato N, Ishimoto T, Sato W, Yuzawa Y, Matsuo S, Kadomatsu K, Maruyama S. CD147/basigin reflects renal dysfunction in patients with acute kidney injury. Clin Exp Nephrol, 2014; 18: 746-754.
  10. Miyashita H, Chikazawa M, Otaki N, Hioki Y, Shimozu Y, Nakashima F, Shibata T, Hagihara Y, Maruyama S, Matsumi N, Uchida K. Lysine pyrrolation is a naturally-occurring covalent modification involved in the production of DNA mimic proteins. Sci Rep, 2014; 4: 5343.
  11. Maeda-Hori M, Kosugi T, Kojima H, Sato W, Inaba S, Maeda K, Nagaya H, Sato Y, Ishimoto T, Ozaki T, Tsuboi N, Muro Y, Yuzawa Y, Imai E, Johnson RJ, Matsuo S, Kadomatsu K, Maruyama S. Plasma CD147 reflects histological features in patients with lupus nephritis. Lupus, 2014; 23: 342-352.
  12. Kim H, Mizuno M, Furuhashi K, Katsuno T, Ozaki T, Yasuda K, Tsuboi N, Sato W, Suzuki Y, Matsuo S, Ito Y, Maruyama S. Rat adipose tissue-derived stem cells attenuate peritoneal injuries in rat zymosan-induced peritonitis accompanied by complement activation. Cytotherapy, 2014; 16: 357-368.
  13. Ito Y, Mizuno M, Suzuki Y, Tamai H, Hiramatsu T, Ohashi H, Ito I, Kasuga H, Horie M, Maruyama S, Yuzawa Y, Matsubara T, Matsuo S, Nagoya Spiro Study G. Long-term effects of spironolactone in peritoneal dialysis patients. J Am Soc Nephrol, 2014; 25: 1094-1102.
2013
  1. Yamamoto J, Sato W, Kosugi T, Yamamoto T, Kimura T, Taniguchi S, Kojima H, Maruyama S, Imai E, Matsuo S, Yuzawa Y, Niki I. Distribution of hydrogen sulfide (H(2)S)-producing enzymes and the roles of the H(2)S donor sodium hydrosulfide in diabetic nephropathy. Clin Exp Nephrol, 2013; 17: 32-40.
  2. Mizuno T, Mizuno M, Imai M, Suzuki Y, Kushida M, Noda Y, Maruyama S, Okada H, Okada N, Matsuo S, Ito Y. Anti-C5a complementary peptide ameliorates acute peritoneal injury induced by neutralization of Crry and CD59. Am J Physiol Renal Physiol, 2013; 305: F1603-1616.
  3. Mizuno M, Suzuki Y, Nonaka K, Sei Y, Maruyama S, Matsuo S, Ito Y. Perforative peritonitis caused by appendicitis in a patient on peritoneal dialysis. Intern Med, 2013; 52: 1177-1181.
  4. Maruyama S. [Progressive renal diseases: recent advances in diagnosis and treatments. Topics: I. Diagnosis; 4. Nephrotic syndrome]. Nihon Naika Gakkai Zasshi, 2013; 102: 1098-1104.
  5. Kojima H, Kosugi T, Sato W, Sato Y, Maeda K, Kato N, Kato K, Inaba S, Ishimoto T, Tsuboi N, Matsuo S, Maruyama S, Yuzawa Y, Kadomatsu K. Deficiency of growth factor midkine exacerbates necrotizing glomerular injuries in progressive glomerulonephritis. Am J Pathol, 2013; 182: 410-419.
  6. Katsuno T, Ozaki T, Saka Y, Furuhashi K, Kim H, Yasuda K, Yamamoto T, Sato W, Tsuboi N, Mizuno M, Ito Y, Imai E, Matsuo S, Maruyama S. Low serum cultured adipose tissue-derived stromal cells ameliorate acute kidney injury in rats. Cell Transplant, 2013; 22: 287-297.
  7. Furuhashi K, Tsuboi N, Shimizu A, Katsuno T, Kim H, Saka Y, Ozaki T, Sado Y, Imai E, Matsuo S, Maruyama S. Serum-starved adipose-derived stromal cells ameliorate crescentic GN by promoting immunoregulatory macrophages. J Am Soc Nephrol, 2013; 24: 587-603.
  8. Chikazawa M, Otaki N, Shibata T, Miyashita H, Kawai Y, Maruyama S, Toyokuni S, Kitaura Y, Matsuda T, Uchida K. Multispecificity of immunoglobulin M antibodies raised against advanced glycation end products: involvement of electronegative potential of antigens. J Biol Chem, 2013; 288: 13204-13214.
2012
  1. Yasuda K, Ozaki T, Saka Y, Yamamoto T, Gotoh M, Ito Y, Yuzawa Y, Matsuo S, Maruyama S. Autologous cell therapy for cisplatin-induced acute kidney injury by using non-expanded adipose tissue-derived cells. Cytotherapy, 2012; 14: 1089-1100.
  2. Toda S, Ito Y, Mizuno M, Suzuki Y, Ito I, Hiramatsu H, Ozaki T, Tsuboi N, Sato W, Maruyama S, Imai E, Matsuo S. Asymptomatic diverticulosis identified by computed tomography is not a risk factor for enteric peritonitis. Nephrol Dial Transplant, 2012; 27: 2511-2516.
  3. Tatematsu M, Yasuda Y, Morita Y, Sakamoto I, Kurata K, Naruse T, Yamamoto R, Tsuboi N, Sato W, Imai E, Matsuo S, Maruyama S. Complete remission within 2 years predicts a good prognosis after methylprednisolone pulse therapy in patients with IgA nephropathy. Clin Exp Nephrol, 2012; 16: 883-891.
  4. Takahashi R, Ito Y, Takahashi H, Ishii H, Kasuga H, Mizuno M, Suzuki Y, Yuzawa Y, Maruyama S, Murohara T, Imai E, Matsuo S. Combined values of serum albumin, C-reactive protein and body mass index at dialysis initiation accurately predicts long-term mortality. Am J Nephrol, 2012; 36: 136-143.
  5. Suzuki Y, Ito Y, Mizuno M, Kinashi H, Sawai A, Noda Y, Mizuno T, Shimizu H, Fujita Y, Matsui K, Maruyama S, Imai E, Matsuo S, Takei Y. Transforming growth factor-beta induces vascular endothelial growth factor-C expression leading to lymphangiogenesis in rat unilateral ureteral obstruction. Kidney Int, 2012; 81: 865-879.
  6. Okada R, Yasuda Y, Tsushita K, Wakai K, Hamajima N, Matsuo S. Glomerular hyperfiltration in prediabetes and prehypertension. Nephrol Dial Transplant, 2012; 27: 1821-1825.
  7. Nishiwaki S, Nakayama T, Saito S, Mizuno H, Ozaki T, Takahashi Y, Maruyama S, Nishida T, Murata M, Kojima S, Naoe T. Efficacy and safety of human adipose tissue-derived mesenchymal stem cells for supporting hematopoiesis. Int J Hematol, 2012; 96: 295-300.
  8. Kato S, Lindholm B, Stenvinkel P, Ekstrom TJ, Luttropp K, Yuzawa Y, Yasuda Y, Tsuruta Y, Maruyama S. DNA hypermethylation and inflammatory markers in incident Japanese dialysis patients. Nephron Extra, 2012; 2: 159-168.
  9. Kato H, Mizuno T, Mizuno M, Sawai A, Suzuki Y, Kinashi H, Nagura F, Maruyama S, Noda Y, Yamada K, Matsuo S, Ito Y. Atrial natriuretic peptide ameliorates peritoneal fibrosis in rat peritonitis model. Nephrol Dial Transplant, 2012; 27: 526-536.
  10. Ito I, Ito Y, Mizuno M, Suzuki Y, Yasuda K, Ozaki T, Kosugi T, Yasuda Y, Sato W, Tsuboi N, Maruyama S, Imai E, Matsuo S. A rare case of acute kidney injury associated with autoimmune hemolytic anemia and thrombocytopenia after long-term usage of oxaliplatin. Clin Exp Nephrol, 2012; 16: 490-494.
  11. Ishii H, Toriyama T, Aoyama T, Takahashi H, Tanaka M, Yoshikawa D, Hayashi M, Yasuda Y, Maruyama S, Matsuo S, Matsubara T, Murohara T. Percutaneous coronary intervention with bare metal stent vs. drug-eluting stent in hemodialysis patients. Circ J, 2012; 76: 1609-1615.
  12. Ishii H, Kumada Y, Takahashi H, Toriyama T, Aoyama T, Tanaka M, Yoshikawa D, Hayashi M, Kasuga H, Yasuda Y, Maruyama S, Matsubara T, Matsuo S, Murohara T. Impact of diabetes and glycaemic control on peripheral artery disease in Japanese patients with end-stage renal disease: long-term follow-up study from the beginning of haemodialysis. Diabetologia, 2012; 55: 1304-1309.
  13. Inaba S, Nagahara S, Makita N, Tarumi Y, Ishimoto T, Matsuo S, Kadomatsu K, Takei Y. Atelocollagen-mediated systemic delivery prevents immunostimulatory adverse effects of siRNA in mammals. Mol Ther, 2012; 20: 356-366.
2011
  1. Watanabe T, Maruyama S, Yamamoto T, Kamo I, Yasuda K, Saka Y, Ozaki T, Yuzawa Y, Matsuo S, Gotoh M. Increased urethral resistance by periurethral injection of low serum cultured adipose-derived mesenchymal stromal cells in rats. Int J Urol, 2011; 18: 659-666.
  2. Suzuki Y, Mizuno M, Nakashima R, Hiramatsu H, Toda S, Sato W, Tsuboi N, Ito I, Maruyama S, Imai E, Matsuo S, Ito Y. A case of perforative peritonitis caused by a piece of bamboo in a patient on peritoneal dialysis. Clin Exp Nephrol, 2011; 15: 962-965.
  3. Sawai A, Ito Y, Mizuno M, Suzuki Y, Toda S, Ito I, Hattori R, Matsukawa Y, Gotoh M, Takei Y, Yuzawa Y, Matsuo S. Peritoneal macrophage infiltration is correlated with baseline peritoneal solute transport rate in peritoneal dialysis patients. Nephrol Dial Transplant, 2011; 26: 2322-2332.
  4. Saka Y, Furuhashi K, Katsuno T, Kim H, Ozaki T, Iwasaki K, Haneda M, Sato W, Tsuboi N, Ito Y, Matsuo S, Kobayashi T, Maruyama S. Adipose-derived stromal cells cultured in a low-serum medium, but not bone marrow-derived stromal cells, impede xenoantibody production. Xenotransplantation, 2011; 18: 196-208.
  5. Saito S, Murakumo Y, Tsuzuki T, Dambara A, Kato T, Enomoto A, Asai N, Maruyama S, Matsuo S, Takahashi M. Analysis of glial cell line-derived neurotrophic factor-inducible zinc finger protein 1 expression in human diseased kidney. Hum Pathol, 2011; 42: 848-858.
  6. Mizuno T, Mizuno M, Morgan BP, Noda Y, Yamada K, Okada N, Yuzawa Y, Matsuo S, Ito Y. Specific collaboration between rat membrane complement regulators Crry and CD59 protects peritoneum from damage by autologous complement activation. Nephrol Dial Transplant, 2011; 26: 1821-1830.
  7. Mizuno M, Ito Y, Tanaka A, Suzuki Y, Hiramatsu H, Watanabe M, Tsuruta Y, Matsuoka T, Ito I, Tamai H, Kasuga H, Shimizu H, Kurata H, Inaguma D, Hiramatsu T, Horie M, Naruse T, Maruyama S, Imai E, Yuzawa Y, Matsuo S. Peritonitis is still an important factor for withdrawal from peritoneal dialysis therapy in the Tokai area of Japan. Clin Exp Nephrol, 2011; 15: 727-737.
  8. Mizuno M, Ito Y, Masuda T, Toda S, Hiramatsu H, Suzuki Y, Ozaki T, Yasuda Y, Ito I, Tsuboi N, Sato W, Maruyama S, Imai E, Matsuo S. A case of fulminant peritonitis caused by Streptococcus mitis in a patient on peritoneal dialysis. Intern Med, 2011; 50: 471-474.
  9. Mizuno M, Ito Y, Hayasaki T, Suzuki Y, Hiramatsu H, Toda S, Mizuno T, Tatematsu M, Ozaki T, Yasuda Y, Sato W, Tsuboi N, Ito I, Maruyama S, Imai E, Matsuo S. A case of acute renal failure caused by cholesterol embolization after carotid artery stenting that was improved by peritoneal dialysis. Intern Med, 2011; 50: 1719-1723.
  10. Kato N, Kosugi T, Sato W, Ishimoto T, Kojima H, Sato Y, Sakamoto K, Maruyama S, Yuzawa Y, Matsuo S, Kadomatsu K. Basigin/CD147 promotes renal fibrosis after unilateral ureteral obstruction. Am J Pathol, 2011; 178: 572-579.
  11. Kato K, Kosugi T, Sato W, Arata-Kawai H, Ozaki T, Tsuboi N, Ito I, Tawada H, Yuzawa Y, Matsuo S, Kadomatsu K, Maruyama S. Growth factor Midkine is involved in the pathogenesis of renal injury induced by protein overload containing endotoxin. Clin Exp Nephrol, 2011; 15: 346-354.
  12. Imai E, Yasuda Y, Horio M, Shibata K, Kato S, Mizutani Y, Imai J, Hayashi M, Kamiya H, Oiso Y, Murohara T, Maruyama S, Matsuo S. Validation of the equations for estimating daily sodium excretion from spot urine in patients with chronic kidney disease. Clin Exp Nephrol, 2011; 15: 861-867.

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