Department of Innovative Biomedical Visualization (iBMV)

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OUTLINE

The aim of this department is to obtain quantitative anatomical, physiological, and pathological information of the central nervous system and other biological tissues through advanced magnetic resonance imaging and artificial intelligence. A primary research focus is the elucidation of the morphology and dynamics of interstitial spaces within the central nervous system, which remain less explored compared with vascular structures, perfusion, and neuronal networks. We investigate neurofluid dynamics, including cerebrospinal and interstitial fluids, as a key frontier for understanding brain function and maintaining brain health. In addition, the department studies the endolymphatic system of the inner ear using artificial intelligence and machine learning–based approaches to develop objective and automated evaluation methods that support consistent patient management.

RESEARCH PROJECTS

• Neurofluid dynamics in the central nervous system
• MRI evaluation of the glymphatic system
• Diffusion MRI: DTI-ALPS(Fig), time-dependent diffusion
• Cerebrospinal fluid and contrast-agent clearance
• Venous and meningeal lymphatic–related spaces
• Neurofluid dynamics in sleep, aging, and disease
• MRI evaluation of the inner ear endolymphatic system
• AI and machine learning–based imaging analysis
• AI applications in radiology and nuclear medicine

BIBLIOGRAPHY