Turning questions from daily clinical practice into peer-reviewed evidence.
Research publications from the Department of Dermatology, Nagoya University, since 2018 are listed in reverse chronological order.
Horisaki K, et al. J Dermatol. 2026
A case series of 15 Japanese patients evaluated clinical outcomes of dacarbazine after failure of immune checkpoint inhibitors.
Miyazaki A, et al. Acta Derm Venereol. 2026
A retrospective cohort study found an association between low subcutaneous adipose tissue and poor prognosis in older patients with cutaneous angiosarcoma.
Fukuda R, et al. Acta Derm Venereol. 2026
A rare case of subcutaneous panniculitis-like T-cell lymphoma arising at widespread tattoo sites with secondary haemophagocytic lymphohistiocytosis was reported.
Miyazaki A, et al. J Dermatol Sci. 2026
The study investigated how plasma-activated Ringer’s lactate induces melanoma-cell apoptosis through heat-shock-protein downregulation and mitochondrial dysfunction.
Kimura T, et al. Commun Med (Lond). 2026
Genomic and transcriptomic profiling of Japanese melanoma samples identified candidate biomarkers associated with clinical benefit from immune checkpoint inhibitors.
Komori T, et al. J Eur Acad Dermatol Venereol. 2026
A multicenter study compared adjuvant anti-PD-1 therapy with observation after resection of nail apparatus melanoma.
Fritzler MJ, Muro Y, et al. J Autoimmun. 2026
The study confirmed striatin-3 as a human autoantigen while clarifying that it does not produce the nuclear staining pattern historically termed SG2NA.
Isobe R, et al. J Dermatol. 2026
A case of anti-RuvBL1/2 antibody-positive systemic sclerosis overlapping with immune-mediated necrotizing myopathy was reported.
Hattori I, et al. J Dermatol. 2025
A deep morphea case positive for anti-Ki/SL, anti-PL-12, and anti-Ro60 antibodies was reported.
Horisaki K, et al. J Dermatol. 2025
The study evaluated associations between best tumor-burden change, prognosis, and treatment-related toxicity during first-line PD-1 monotherapy for advanced melanoma.
Noda E, et al. J Dermatol. 2025
A case of immune-checkpoint-inhibitor-induced IgA vasculitis with abundant IgA anti-endothelial cell antibodies was described.
Akashi N, et al. J Dermatol. 2025
A pregnant patient with systemic sclerosis achieved control of vascular and other symptoms with rituximab and had a safe pregnancy and delivery.
Suzuki Y, et al. J Dermatol. 2025
A questionnaire study examined how congenital ichthyosis affects educational attainment and career choices throughout life.
Omi M, et al. J Dermatol Sci. 2025
A Japanese–Taiwanese multicenter cohort of 99 extramammary Paget disease cases was analyzed for FOXA1 and ERBB2 activating mutations.
Omi M, et al. Acta Derm Venereol. 2024
A case of adult CHILD syndrome showed marked improvement of skin lesions after topical treatment with 2% ketoconazole cream.
Koizumi H, et al. Rheumatology (Oxford). 2024
An ELISA for anti-eIF2B antibodies was established and used to evaluate their detection and clinical relevance in Japanese patients with systemic sclerosis.
Ebata A, et al. J Am Acad Dermatol. 2024
The study demonstrated increased JAK signalling in cutaneous vasculitis lesions, suggesting a potential pathway for disease understanding and therapeutic targeting.
Suzuki Y, et al. J Dermatol Sci. 2024
A nationwide survey of 100 patients assessed disease severity, quality of life, and the benefits and burdens of existing treatments for congenital ichthyoses.
Ogawa-Momohara M, et al. Br J Dermatol. 2023
Changes in allergen-specific IgG4 during long-term dupilumab therapy suggested an additional immunomodulatory effect in atopic dermatitis.
Kamiya S, et al. J Dermatol. 2023
A case of microscopic polyangiitis with cutaneous manifestations was successfully controlled using avacopan without conventional high-dose glucocorticoid therapy.
Muro Y, et al. Autoimmun Rev. 2022
Novel autoantibodies targeting cysteinyl- and valyl-tRNA synthetases were identified, expanding the autoantibody spectrum of antisynthetase syndrome.
Yamashita Y, et al. Rheumatology (Oxford). 2022
An ELISA for anti-NOR90 antibodies was developed to examine associations with systemic sclerosis, interstitial lung disease, and malignancy.
Muro Y, et al. J Autoimmun. 2021
Anti-OJ-positive sera were shown to recognize KARS and IARS, enabling development of practical ELISA assays for anti-OJ antibodies.
Takeichi T, Akiyama M. J Dermatol. 2021
Systemic inflammatory disorders caused by germline EGFR mutations were discussed within the framework of autoinflammatory keratinization diseases.
Takeichi T, et al. Cancers (Basel). 2020
Genomic analysis of 48 extramammary Paget disease cases identified FOXA1 alterations in approximately 23%, suggesting new biological and therapeutic targets.
Takeichi T, et al. J Clin Invest. 2020
SDR9C7 was shown to catalyse a critical acylceramide dehydrogenation step required for the corneocyte lipid envelope and epidermal barrier formation.
Murase Y, et al. J Dermatol Sci. 2020
NIPAL4-related congenital ichthyosis showed reduced stratum corneum acylceramides together with increased IL-17- and IL-36-related inflammatory signals.
Yamaguchi K, et al. Clin Rheumatol. 2019
Spontaneous pneumomediastinum in anti-MDA5-positive dermatomyositis was associated with more severe lung disease and a higher risk of mortality.
Murase Y, et al. J Allergy Clin Immunol. 2019
Aberrant CARD14 function was linked to defective epidermal barrier formation and a severe atopic dermatitis-like phenotype.
Akiyama M. J Allergy Clin Immunol. 2019
Early-onset generalized pustular psoriasis was positioned as a representative autoinflammatory keratinization disease at the intersection of epidermal genetics and innate inflammation.
Ogawa-Momohara M, et al. Clin Exp Rheumatol. 2019
The clinical course and prognosis of dysphagia in dermatomyositis highlighted the importance of swallowing assessment in systemic disease management.
Takeichi T, et al. J Lipid Res. 2018
Neu-Laxova syndrome caused by PHGDH deficiency showed broad reductions in stratum corneum ceramides, providing insight into ichthyosis and barrier dysfunction.
Yamaguchi K, et al. Respir Med. 2018
Coexisting myositis-associated autoantibodies in anti-MDA5-positive clinically amyopathic dermatomyositis were associated with less rapidly progressive interstitial lung disease and better outcomes.
Kobayashi T, et al. J Endocr Soc. 2018
A prospective nivolumab cohort showed that baseline antithyroid antibodies were associated with the risk of immune-related destructive thyroiditis.
Publications are listed based on bibliographic records verified as work from the Department of Dermatology, Nagoya University.
