Faculty Members

Faculty	Position	Department
IIMA Mami	Designated Professor	Fundamental Development for Advanced Low Invasive Diagnostic Imaging
HYODO Ryota	Assistant Lecturer	Fundamental Development for Advanced Low Invasive Diagnostic Imaging

Bibliography

• 2025

  1. Iima M, Mizuno R, Kataoka M, Tsuji K, Yamazaki T, Minami A, Honda M, Imanishi K, Takada M, Nakamoto Y. Deep Learning Applied to Diffusion-weighted Imaging for Differentiating Malignant from Benign Breast Tumors without Lesion Segmentation. Radiology: Artificial Intelligence. 2025; 7(1).
  2. Honda M, Kataoka M, Iima M, Ota R, Okazawa A, Fukushima Y, Nickel M. D., Sato F., Masuda N, Okada T, Nakamoto Y. Institutional Variability in Ultrafast Breast MR Imaging: Comparing Compressed Sensing and View Sharing Techniques with Different Patient Populations and Contrast Injection Protocols. Magn Reson Med Sci. 2025 Feb 8. doi: 10.2463/mrms.mp.2024-0152.
  3. Basukala D, Mikheev A, Li X., Goldberg J. D, Gilani N, Moy L, Pinker K, Partridge S. C, Biswas D, Kataoka M, Honda M, Iima M, Thakur S. B, Sigmund E. E. Retrospective BReast Intravoxel Incoherent Motion Multisite (BRIMM) multisoftware study. Front Oncol. 2025 Feb 24:15:1524634. doi: 10.3389/fonc.2025.1524634.
  4. Kataoka M, Iima M. Time to Consider Diffusion Time: Exploring the Potential of Time-Dependent Diffusion MRI in Breast Cancer Imaging. Radiology: Imaging Cancer. 2025;7(3):e250129.

• 2024

  1. Tanaka H, Koyasu S, Kikuchi M, Iima M, Omori K, Nakamoto Y. Utility of Diffusion-weighted MR Imaging for Evaluating the Depth of Invasion in Oral Tongue Squamous Cell Carcinoma. Magn Reson Med Sci. 2024;24(2):210-219.
  2. Someya Y, Iima M, Imai H, Isoda H, Ohno T, Kataoka M, Le Bihan D, Nakamoto Y. In Vivo and Post-mortem Comparisons of IVIM/Time-dependent Diffusion MR Imaging Parameters in Melanoma and Breast Cancer Xenograft Models. Magn Reson Med Sci. 2025 Jul 31;24(4). doi: 10.2463/mrms.mp.2023-0078.
  3. Iima M, Nakayama R, Kataoka M, Otikovs M, Nissan N, Frydman L, Urushibata Y, Honda M, Okazawa A, Satake H, Naganawa S, Nakamoto Y. Comparing Lesion Conspicuity and ADC Reliability in High-resolution Diffusion-weighted Imaging of the Breast. Magn Reson Med Sci. 2024 Sep 26. doi: 10.2463/mrms.tn.2024-0089.
  4. Sugimoto M, Horiguchi R, Ikeda S, Kawai Y, Niimi K, Hyodo R, Banno H. The immediate post-operative impact of infrarenal aortic endografts on renal arterial flow dynamics: Insights from four-dimensional flow magnetic resonance imaging analysis. Vascular. 2024;23:17085381241277651.
  5. Hyodo R, Takehara Y, Ishizu Y, Nishida K, Mizuno T, Ichikawa K, Horiguchi R, Kurata N, Ogura Y, Yokoyama S, Naganawa S, Jin N, Ichiba Y. Evaluation of 4D Flow MRI-Derived Relative Residence Time as a Marker for Cirrhosis Associated Portal Vein Thrombosis. J Magn Reson Imaging. 2024;60:2592-2601.
  6. Takehara Y, Hyodo R. Editorial for \\\"Comparative Performance of 2018 LI-RADS versus Modified LIRADS (mLI-RADS): An Individual Participant Data Meta-Analysis\\\". Journal of Magnetic Resonance Imaging 2024;60:1092-1093.
  7. Iima M, Kataoka M, Honda M, Le Bihan D. Diffusion-Weighted MRI for the Assessment of Molecular Prognostic Biomarkers in Breast Cancer. Korean journal of radiology. 2024;25(7):623-633.
  8. Honda M, Sigmund E, Le Bihan D, Pinker K, Clauser P, Karampinos D, Partridge S, Fallenberg E, Martincich L, Baltzer P, Mann R, Camps-Herrero J., Iima M. Advanced breast diffusion-weighted imaging: what are the next steps? A proposal from the EUSOBI International Breast Diffusion-weighted Imaging working group. European Radiology. 2024;35(4):2130-2140.
  9. Iima M, Honda M, Satake H, Kataoka M. Standardization and advancements efforts in breast diffusion-weighted imaging. Japanese Journal of Radiology. 2024;43(3):347-354.
  10. Minami A, Mizuno R, Kataoka M, Iima M. Comments on “A Channel‐Dimensional Feature‐Reconstructed Deep Learning Model for Predicting Breast Cancer Molecular Subtypes on Overall b‐Value Diffusion‐Weighted MRI”. Journal of Magnetic Resonance Imaging. 2024; 60(5):2237-2238.
  11. Kataoka M, Iima M. Potential of the Diffusion-based Noncontrast Protocol for Breast Imaging: Current Status and Hints for Improvements. Radiology. 2024;311(2):e241058.
  12. Honda M, Iima M. It Is Time to Use Apparent Diffusion Coefficient in Breast MRI Diagnostics. Radiology. 2024;310(2):e24901.
  13. Iima M, Miki Y, Naganawa S. 40 years of diffusion MRI: a journey from basic science to clinical breakthrough. Japanese Journal of Radiology. 2024;42(2):1355-1356.

• 2023

  1. Hyodo R, Takehara Y, Mizuno T, Ichikawa K, Horiguchi R, Kawakatsu S, Mizuno T, Ebata T, Naganawa S, Jin N, Ichiba Y. Four-dimensional Flow MRI Assessment of Portal Hemodynamics and Hepatic Regeneration after Portal Vein Embolization. Radiology. 2023 Sep;308(3):e230709. doi: 10.1148/radiol.230709.
  2. Horiguchi R, Takehara Y, Sugiyama M, Hyodo R, Komada T, Matsushima M, Naganawa S, Mizuno T, Sakurai Y, Sugimoto M, Banno H, Komori K, Itatani K. Postendovascular Aneurysmal Repair Increase in Local Energy Loss for Fusiform Abdominal Aortic Aneurysm: Assessments With 4D flow MRI. J Magn Reson Imaging. 2023;57:1199-1211.

• 2022

  1. de Boer A, Villa G, Bane O, Bock M, Cox EF, Dekkers IA, Eckerbom P, Fernández-Seara MA, Francis ST, Haddock B, Hall ME, Hall Barrientos P, Hermann I, Hockings PD, Lamb HJ, Laustsen C, Lim RP, Morris DM, Ringgaard S, Serai SD, Sharma K, Sourbron S, Takehara Y, Wentland AL, Wolf M, Zöllner FG, Nery F, Caroli A. Consensus-Based Technical Recommendations for Clinical Translation of Renal Phase Contrast MRI. J Magn Reson Imaging. 255(2):323-335. 2022 Feb
  2. Itatani K, Sekine T, Yamagishi M, Maeda Y, Higashitani N, Miyazaki S, Matsuda J, Takehara Y. Hemodynamic Parameters for Cardiovascular System in 4D Flow MRI: Mathematical Definition and Clinical Applications. Magn Reson Med Sci. 21(2):380-399. 2022 Mar 1
  3. Takehara Y, Sekine T, Obata T. Why 4D Flow MRI? Real Advantages. Magn Reson Med Sci. 21(2):253-256. 2022 Mar 1
  4. Sugiyama M, Takehara Y, Naganawa S. Does the Pulsatile Non-uniform Flow Matter in MR Flowmetry? Magn Reson Med Sci. 21(2):365-371. 2022 Mar 1
  5. Terada M, Takehara Y, Isoda H, Wakayama T, Nozaki A. Technical Background for 4D Flow MR Imaging. Magn Reson Med Sci. 21(2):267-277. 2022 Mar 1
  6. Takehara Y. Clinical Application of 4D Flow MR Imaging for the Abdominal Aorta. Magn Reson Med Sci. 21(2):354-364. 2022 Mar 1
  7. Hyodo R, Takehara Y, Naganawa S. 4D Flow MRI in the portal venous system: imaging and analysis methods, and clinical applications. Radiol Med. 2022;127:1181-1198.

• 2021

  1. Suzuki K, Takehara Y, Sakata M, Kawate M, Ohishi N, Sugiyama K, Akai T, Suzuki Y, Sugiyama M, Kawamura T, Morita Y, Kikuchi H, Hiramatsu Y, Yamamoto M, Nasu H, Johnson K, Oliver Wieben, Kurachi K, Takeuchi H. Daikenchuto increases blood flow in the superior mesenteric artery in humans: A comparison study between four-dimensional phase-contrast vastly undersampled isotropic projection reconstruction magnetic resonance imaging and Doppler ultrasound. PLoS One. 16(1):e0245878. 2021 Jan 27
  2. Ryota Hyodo, Yasuo Takehara, Takashi Mizuno, Kazushige Ichikawa, Yasuhiro Ogura , Shinji Naganawa. Portal Vein Stenosis Following Liver Transplantation Hemodynamically Assessed with 4D-flow MRI before and after Portal Vein Stenting. Magn Reson Med Sci. 20(3):231-235. 2021 Sep 1
  3. Ryota Horiguchi, Hiroshi Ogawa, Naoya Nagai, Yasuo Takehara, Shinji Naganawa. Yukihiro Yokoyama, Yoshie Shimoyama. A case of intraductal tubulopapillary neoplasm of the pancreas originating from the branch duct: cast in the mold sign. Nagoya J Med Sci. 83(4):869-875. 2021 Nov
  4. Takahashi M, Takehara Y, Fujisaki K, Okuaki T, Fukuma Y, Tooyama N, Ichijo K, Amano T, Goshima S, Naganawa S. Three Dimensional Ultra-short Echo Time MRI Can Depict Cholesterol Components of Gallstones Bright. Magn Reson Med Sci. 20(4):359-370. 2021 Dec 1
  5. Hyodo R, Takehara Y, Nishida A, Matsushima M, Naganawa S. “Speckled Enhancement” on Gd-EOB-DTPA Enhanced MR Imaging of Primary Hepatic Mucosa-associated Lymphoid Tissue Lymphoma. Magn Reson Med Sci. doi: 10.2463/mrms.mp.2021-0069. 2021 Oct 7
  6. Inoue J, Matsuo K, Iwabuchi T, Takehara Y, Yamasue H. How Memory Switches Brain Responses of Patients with Post-traumatic Stress Disorder. Cereb Cortex Commun. 2(2):tgab021. 2021 Mar 20
  7. Hyodo R, Takehara Y, Mizuno T, Ichikawa K, Yokoyama S, Ishizu Y, Naganawa S. Assessing the Complicated Venous Hemodynamics and Therapeutic Outcomes of Budd-Chiari Syndrome with Respiratory-gated 4D Flow MR Imaging During the Expiratory and Inspiratory Phases. Magn Reson Med Sci. 22(1):1-6. doi: 10.2463/mrms.ici.2021-0110.
  8. Miyajima K, Urushida T, Ito K, Kin F, Okazaki A, Takashima Y, Watanabe T, Kawaguchi Y, Wakabayashi Y, Takehara Y, Maekawa Y. Four-dimensional flow magnetic resonance imaging visualizes reverse vortex pattern and energy loss increase in left bundle branch block. Europace. euab299. doi: 10.1093/europace/euab299. 2021 Dec 17
  9. Hyodo R, Takehara Y, Mizuno T, Ichikawa K, Ishizu Y, Sugiyama M, Naganawa S. Time-resolved 3D cine phase-contrast magnetic resonance imaging (4D-flow MRI) can quantitatively assess portosystemic shunt severity and confirm normalization of portal flow after embolization of large portosystemic shunts. Hepatol Res. 51(3):343-349. 2021 Mar
  10. Ogawa H, Takehara Y, Naganawa S. Imaging diagnosis of autoimmune pancreatitis: computed tomography and magnetic resonance imaging. J Med Ultrason (2001) 48(4):565-571. 2021 Oct

• 2020

  1. Perera R, Isoda H, Ishiguro K, Mizuno T, Takehara Y, Terada M, Tanoi C, Naito T, Sakahara H, Hiramatsu H, Namba H, Izumi T, Wakabayashi T, Kosugi T, Onishi Y, Alley M, Komori Y, Ikeda M, Naganawa S. Assessing the Risk of Intracranial Aneurysm Rupture Using Morphological and Hemodynamic Biomarkers Evaluated from Magnetic Resonance Fluid Dynamics and Computational Fluid Dynamics. Magn Reson Med Sci. 19(4):333-344. 2020 Dec 1
  2. Sugiyama M, Takehara Y, Kawate M, Ooishi N, Terada M, Isoda H, Sakahara H, Naganawa S, Kevin M. Johnson, Oliver Wieben, Wakayama T, Nozaki A, Kabasawa H. Optimal Plane Selection for Measuring Post-prandial Blood Flow Increase within the Superior Mesenteric Artery: Analysis Using 4D Flow and Computational Fluid Dynamics. Magn Reson Med Sci. 19(4):366-374. 2020 Dec 1
  3. Umakoshi H, Nihashi T, Shimamoto H, Yamada T, Ishiguchi H, Takada A, Hirasawa N, Ishihara S, Takehara Y, Naganawa S, Matthew Davenport, Terasawa T. Pharmacologic and non-pharmacologic interventions to prevent hypersensitivity reactions of non-ionic iodinated contrast media: a systematic review protocol. BMJ Open. 10(3):e033023. 2020 Mar 9
  4. Takehara Y, Isoda H, Takahashi M, Unno N, Shiiya N, Ushio T, Goshima S, Naganawa S, Marcus Alley, Wakayama T, Nozaki A. Abnormal Flow Dynamics Result in Low Wall Shear Stress and High Oscillatory Shear Index in Abdominal Aortic Dilatation: Initial in vivo Assessment with 4D-flow MRI. Magn Reson Med Sci. 19(3):235-246. 2020 Aug 3
  5. Karayama M, Yoshizawa N, Sugiyama M, Mori K, Yasui H, Hozumi H, Suzuki Y, Furuhashi K, Fujisawa T, Enomoto N, Nakamura Y, Inui N, Goshima S, Suda T, Takehara Y. Intravoxel incoherent motion magnetic resonance imaging for predicting the long-term efficacy of immune checkpoint inhibitors in patients with non-small-cell lung cancer. Lung Cancer. 143:47-54. 2020 May
  6. Takehara Y. 4D Flow when and how? Radiol Med. 125 (9) 838-850. 2020
  7. Motosugi U, Takehara Y. Motion and solution in hepatobiliary agent-enhanced dynamic MRI: solid evidence and unanswered question. Jpn J Radiol. 38(2):99-100. 2020 Feb

• 2019

  1. Ogawa H, Takehara Y, Naganawa S, Yamaguchi J, Nakaguro M. A case of human pancreatic eurytremiasis. Abdom Radiol (NY). 44(4):1213-1216. 2019 Apr.
  2. Katahashi K, Sano M, Takehara Y, Inuzuka K, Sugiyama M, Alley MT, Takeuchi H, Unno N. Flow dynamics of type II endoleaks can determine sac expansion after endovascular aneurysm repair using four-dimensional flow-sensitive magnetic resonance imaging analysis. J Vasc Surg. 70(1):107-116.e1. 2019 Jul
  3. Watanabe T, Isoda H, Fukuyama A, Takahashi M, Amano T, Takehara Y, Oishi N, Kawate M, Terada M, Kosugi T, Komori Y, Fukuma Y, Alley M. Accuracy of the Flow Velocity and Three-directional Velocity Profile Measured with Three-dimensional Cine Phase-contrast MR Imaging: Verification on Scanners from Different Manufacturers. Magn Reson Med Sci. 18(4):265-271. 2019 Oct 15
  4. Uchida W, Tokuda Y, Takehara Y, Usui A. Mechanical haemolytic anaemia assessed with four-dlmenslonal flow cardiac magnetic resonance. Eur J Cardiothorac Surg. 56(4):813-814. 2019 Oct 1

• 2018

  1. Watanabe T, Isoda H, Takehara Y, Terada M, Naito T, Kosugi T, Onishi Y, Tanoi C, Izumi T. Hemodynamic vascular biomarkers for initiation of paraclinoid internal carotid artery aneurysms using patient-specific computational fluid dynamic simulation based on magnetic resonance imaging. Neuroradiology. 2018 Mar 8.

• 2017

  1. Miyazaki S, Itatani K, Furusawa T, Nishino T, Sugiyama M, Takehara Y, Yasukochi S. Validation of numerical simulation methods in aortic arch using 4D Flow MRI. Heart Vessels. 2017 Aug;32(8):1032-1044.
  2. Motoyama D, Ishii Y, Takehara Y, Sugiyama M, Yang W, Nasu H, Ushio T, Hirose Y, Ohishi N, Wakayama T, Kabasawa H, Johnson K, Wieben O, Sakahara H, Ozono S.Four-dimensional phase-contrast vastly undersampled isotropic projection reconstruction (4D PC-VIPR) MR evaluation of the renal arteries in transplant recipients: Preliminary results. J Magn Reson Imaging. 2017 Aug;46(2):595-603.
  3. Natsume K, Shiiya N, Takehara Y, Sugiyama M, Satoh H, Yamashita K, Washiyama N. Characterizing saccular aortic arch aneurysms from the geometry-flow dynamics relationship. J Thorac Cardiovasc Surg. 2017 Jun;153(6):1413-1420.

• 2016

  1. Suwa K, Saitoh T, Takehara Y, Sano M, Saotome M, Urushida T, Katoh H, Satoh H,Sugiyama M, Wakayama T, Alley M, Sakahara H, Hayashi H. Intra-left ventricular flow dynamics in patients with preserved and impaired left ventricular function: Analysis with 3D cine phase contrast MRI (4D-Flow). J Magn Reson Imaging. 2016 Dec;44(6):1493-1503.
  2. Yoshizawa N, Ueda Y, Nasu H, Ogura H, Ohmae E, Yoshimoto K, Takehara Y,Yamashita Y, Sakahara H. Effect of the chest wall on the measurement of hemoglobin concentrations by near-infrared time-resolved spectroscopy in normal breast and cancer. Breast Cancer. 2016 Nov;23(6):844-850.
  3. Odagiri K, Inui N, Hakamata A, Inoue Y, Suda T, Takehara Y, Sakahara H,Sugiyama M, Alley MT, Wakayama T, Watanabe H. Non-invasive evaluation of pulmonary arterial blood flow and wall shear stress in pulmonary arterial hypertension with 3D phase contrast magnetic resonance imaging. Springerplus.2016 Jul 13;5(1):1071.
  4. Sakata M, Takehara Y, Katahashi K, Sano M, Inuzuka K, Yamamoto N, Sugiyama M, Sakahara H, Wakayama T, Alley MT, Konno H, Unno N. Hemodynamic Analysis of Endoleaks After Endovascular Abdominal Aortic Aneurysm Repair by Using 4-Dimensional Flow-Sensitive Magnetic Resonance Imaging. Circ J. 2016 Jul 25;80(8):1715-25.
  5. Sakai N, Takehara Y, Yamashita S, Ohishi N, Kawaji H, Sameshima T, Baba S,Sakahara H, Namba H. Shear Stiffness of 4 Common Intracranial Tumors Measured Using MR Elastography: Comparison with Intraoperative Consistency Grading. AJNR Am J Neuroradiol. 2016 Jun 23. [Epub ahead of print]
  6. Sato Y, Nakahara K, Shimada M, Hara Y, Takayanagi D, Sawada N, Mukai S,Shimada S, Yamaguchi N, Hidaka E, Takehara Y, Ishida F, Kudo SE. Donor Left-Sided Heptectomy by Use of the Real-Time Moving Windows Method With 8-Centimeter Transverse Skin Incision. Transplant Proc. 2016 May;48(4):1083-6.
  7. Yoshihara S, Matsunaga M, Yaegashi T, Suzuki S, Naito M, Takehara Y. Unusual Serial Electrocardiographic Changes which Progressed to Arrhythmogenic Right Ventricular Cardiomyopathy. Intern Med. 2016;55(9):1103-8.
  8. Tsushima Y, Ishiguchi T, Murakami T, Hayashi H, Hayakawa K, Fukuda K, Korogi Y, Sugimoto H, Takehara Y, Narumi Y, Arai Y, Kuwatsuru R, Yoshimitsu K, Awai K,Kanematsu M, Takagi R. Safe use of iodinated and gadolinium-based contrast media in current practice in Japan: a questionnaire survey. Jpn J Radiol. 2016 Feb;34(2):130-9.
  9. Yamashita Y, Murayama S, Okada M, Watanabe Y, Kataoka M, Kaji Y, Imamura K, Takehara Y, Hayashi H, Ohno K, Awai K, Hirai T, Kojima K, Sakai S, Matsunaga N, Murakami T, Yoshimitsu K, Gabata T, Matsuzaki K, Tohno E, Kawahara Y, Nakayama T,Monzawa S, Takahashi S. The essence of the Japan Radiological Society/Japanese College of Radiology Imaging Guideline. Jpn J Radiol. 2016 Jan;34(1):43-79.
  10. Terada M, Takehara Y, Isoda H, Uto T, Matsunaga M, Alley M. Low WSS and High OSI Measured by 3D Cine PC MRI Reflect High Pulmonary Artery Pressures in Suspected Secondary Pulmonary Arterial Hypertension. Magn Reson Med Sci. 2016;15(2):193-202.

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