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Manami Oya, Yoshiki Miyasaka, Yoshiko Nakamura, Miyako Tanaka, Takayoshi Suganami, Tomoji Mashimo, Kazuhiro Nakamura. Age-related ciliopathy: Obesogenic shortening of melanocortin-4 receptor-bearing neuronal primary cilia. Cell Metab. 2024 Feb 27:S1550-4131(24)00056-1.
Koji Wakatsuki, Sumiko Kiryu-Seo, Masaya Yasui, Hiroki Yokota, Haruku Kida, Hiroyuki Konishi, Hiroshi Kiyama. Repeated cold stress, an animal model for fibromyalgia, elicits proprioceptor-induced chronic pain with microglial activation in mice. J Neuroinflammation. 2024 Jan 18;21(1):25.
J. Sarangi, A. Ido, M. Ito, C. Iinuma, Y. Doyama, W. Jin, J. Wachino, M. Suzuki, M. Iguchi, T. Yagi, Y. Arakawa, K. Kimura. Clinical isolates of Streptococcus mitis/oralis-related species with reduced carbapenem susceptibility, harboring amino acid substitutions in penicillin-binding proteins in Japan. Antimicrob Agents Chemother. 2024 Apr 3;68(4):e0117923.
Yuji Kondo, Yuxin Li and Tetsuya Okajima. Efficient Escorting Strategy for Aggregation-Prone Notch EGF Repeats with Sparcl1. Molecules 2024, 29, 1031.
Patricia Angela Sibal, Shigeru Matsumura, Toru Ichinose, Itzel Bustos-Villalobos, Daishi Morimoto, Ibrahim R. Eissa, Mohamed Abdelmoneim, Mona Alhussein Mostafa Aboalela, Nobuaki Mukoyama, Maki Tanaka, Yoshinori Naoe, Hideki Kasuya. STING activator 2'3'-cGAMP enhanced HSV-1-based oncolytic viral therapy. Mol Oncol. 2024.
Elgendy M, Tamada H, Taira T, Iio Y, Kawamura A, Kunogi A, Mizutani Y, Kiyama H. Dynamic changes in endoplasmic reticulum morphology and its contact with the plasma membrane in motor neurons in response to nerve injury. Cell Tissue Res. 2024 Feb 5.
Ken Sagou, Yoshitaka Sato, Yusuke Okuno, Takahiro Watanabe, Tomoki Inagaki, Yashiro Motooka, Shinya Toyokuni, Takayuki Murata, Hitoshi Kiyoi, Hiroshi Kimura. Epstein-Barr virus lytic gene BNRF1 promotes B-cell lymphomagenesis via IFI27 upregulation. PLoS Pathog 20(2): e1011954.
Mami Kuwamura, Kentaro Tanaka, Atsuto Onoda, Kentaro Taki, Chihaya Koriyama, Kyoko Kitagawa, Toshihiro Kawamoto & Mayumi Tsuji. Measurement of Bisphenol A Diglycidyl Ether (BADGE), BADGE derivatives, and Bisphenol F Diglycidyl Ether (BFDGE) in Japanese infants with NICU hospitalization history. BMC Pediatrics volume 24, Article number: 26 (2024).
Iguchi Y, Takahashi Y, Li J, Araki K, Amakusa Y, Kawakami Y, Kobayashi K, Yokoi S, Katsuno M. IκB kinase phosphorylates cytoplasmic TDP-43 and promotes its proteasome degradation. J Cell Biol. 2024 Feb 5;223(2):e202302048.
Israt Jahan, Ryota Adachi, Ryo Egawa, Haruka Nomura and Hiroshi Kuba. CDK5/p35-Dependent Microtubule Reorganization Contributes to Homeostatic Shortening of the Axon Initial Segment. J Neurosci. 2023 Jan 18;43(3):359-372.
Hiraiwa H, Morimoto R, Tsuyuki Y, Ushida K, Ito R, Kazama S, Kimura Y, Araki T, Mizutani T, Oishi H, Kuwayama T, Kondo T, Okumura T, Murohara T. The balance of CD8-positive T cells and PD-L1 expression in the myocardium predicts prognosis in lymphocytic fulminant myocarditis. Cardiology 2024;149:28-39.
Norihiro Imai, Yuki Ohsaki, Jinglei Cheng, Jingjing Zhang, Fumitaka Mizuno, Taku Tanaka, Shinya Yokoyama, Kenta Yamamoto, Takanori Ito, Yoji Ishizu, Takashi Honda, Masatoshi Ishigami, Hiroaki Wake, Hiroki Kawashima . Distinct features of two lipid droplets types in cell nuclei from patients with liver diseases. Sci Rep. 2023 Apr 26;13(1):6851.
Tamada H. Three-dimensional ultrastructure analysis of organelles in injured motor neuron. Anat Sci Int. 2023 Jul;98(3):360-369.
Miho M. Suzuki, Kenta Iijima, Koichi Ogami, Keiko Shinjo, Yoshiteru Murofushi, Jingqi Xie, Xuebing Wang, Yotaro Kitano, Akira Mamiya, Yuji Kibe, Tatsunori Nishimura, Fumiharu Ohka, Ryuta Saito, Shinya Sato, Junya Kobayashi, Ryoji Yao, Kanjiro Miyata, Kazunori Kataoka, Hiroshi I. Suzuki, Yutaka Kondo. TUG1-mediated R-loop resolution at microsatellite loci as a prerequisite for cancer cell proliferation. Nature Communications (2023) 14:4521.
Hattori Y, Kato D, Murayama F, Koike S, Asai H, Yamasaki A, Naito Y, Kawaguchi A, Konishi H, Prinz M, Masuda T, Wake H, Miyata T. CD206+ macrophages transventricularly infiltrate the early embryonic cerebral wall to differentiate into microglia. Cell Rep., 42(2), 112092 (2023).
Kosuke Yoshida, Akira Yokoi, Masami Kitagawa, Mai Sugiyama, Tomofumi Yamamoto, Jun Nakayama, Hiroshi Yoshida, Tomoyasu Kato, Hiroaki Kajiyama, Yusuke Yamamoto. Downregulation of miR-10b-5p facilitates the proliferation of uterine leiomyosarcoma cells: A microRNA sequencing-based approach. Oncol Rep. 2023 May;49(5):86.
Hyodo T, Asano-Inami E, Ito S, Sugiyama M, Nawa A, Rahman ML, Hasan MN, Mihara Y, Lam VQ, Karnan S, Ota A, Tsuzuki S, Hamaguchi M, Hosokawa Y, Konishi H. Leucine zipper protein 1 (LUZP1) regulates the constriction velocity of the contractile ring during cytokinesis. The FEBS Journal 2023 Nov.
Ando, R., Shiraki, Y., Miyai, Y., Shimizu, H., Furuhashi, K., Minatoguchi, S., Kato, K., Kato, A., Iida, T., Mizutani, Y., Ito, K., Asai, N., Mii, S., Esaki, N., Takahashi, M. and Enomoto, A.. Meflin is a marker of pancreatic stellate cells involved in fibrosis and epithelial regeneration in the pancreas. J. Pathol. 2023.
Ryo Fukaura, Chiaki Terashima-Murase, Shoichiro Mori, Yukiko Higa, Masashi Akiyama. Myiasis on a spindle cell squamous cell carcinoma: A scanning electron microscope observation of Lucilia sericata larvae. J Dermatol. 2023 Jul;50(7):964-966.
Ryosuke Okuno, Yu Inoue, Yuichi Hasebe, Toshio Igarashi, Mika Kawagishi-Hotta, Takaaki Yamada, Seiji Hasegawa. Genome-wide association studies in the Japanese population identified genetic loci and target gene associated with epidermal turnover. Experimental Dermatology. 2023;00:1.
Jun Ouchida, Tomoya Ozaki, Naoki Segi, Yuji Suzuki, Shiro Imagama, Kenji Kadomatsu, Kazuma Sakamoto. Glypican-2 defines age-dependent axonal response to chondroitin sulfate. Exp Neurol. 2023 Aug;366:114444.
Hiroki Katsuta, Satoru Okuda, Kazuaki Nagayama, Hiroaki Machiyama, Satoru Kidoaki, Masashi Kato, Masahiro Sokabe, Takaki Miyata, Hiroaki Hirata. Actin crosslinking by α-actinin averts viscous dissipation of myosin force transmission in stress fibers. iScience 26, 106090, March 17, 2023.
Xuboya Chang, Satoshi Tamauchi, Kosuke Yoshida, Masato Yoshihara, Akira Yokoi, Yusuke Shimizu, Yoshiki Ikeda, Nobuhisa Yoshikawa, Tohru Kiyono, Yusuke Yamamoto, Hiroaki Kajiyama. Downregulating vaccinia-related kinase 1 by luteolin suppresses ovarian cancer cell proliferation by activating the p53 signaling pathway. Gynecol Oncol. 2023 Jun;173:31-40.
Miyoko Matsushima, Haruka Nose, Hikaru Tsuzuki, Masahiro Takekoshi, Yuto Kusatsugu, Hinata Taniguchi, Tomoko Ohdachi, Naozumi Hashimoto, Mitsuo Sato, Tsutomu Kawabe. Decrease in cholesterol in the cell membrane is essential for Nrf2 activation by quercetin. J Nutr Biochem. 2023 Mar 21;109329.
Bo Xie, Chiya Numako, Takashi Naka, and Seiichi Takami. Supercritical Hydrothermal Synthesis of Spinel-Type Nonstoichiometric Cobalt Gallate Nanoparticles and Their Magnetic Properties. Cryst. Growth Des. 2023, 23, 4, 2511-2521.
Hattori Y, Itoh H, Tsugawa Y, Nishida Y, Kurata K, Uemura A, Miyata T. Embryonic Pericytes Promote Microglial Homeostasis and Their Effects on Neural Progenitors in the Developing Cerebral Cortex. J. Neurosci., 42(3), 362-373 (2022).
Rinako Tanaka, Jingzhu Liao, Kazuhiro Hada, Daisuke Mori, Taku Nagai, Tetsuo Matsuzaki, Toshitaka Nabeshima, Kozo Kaibuchi, Norio Ozaki, Hiroyuki Mizoguchi, Kiyofumi Yamada. Inhibition of Rho-kinase ameliorates decreased spine density in the medial prefrontal cortex and methamphetamine-induced cognitive dysfunction in mice carrying schizophrenia-associated mutations of the Arhgap10 gene. Pharmacol Res. 2022 Nov 30;187:106589.
Kenichi Mishima, Yuka Tsukagoshi Okabe, Masaaki Mizuno, Kinji Ohno, Hiroshi Kitoh & Shiro Imagama . Efficacy of soluble lansoprazole-impregnated beta-tricalcium phosphate for bone regeneration. Sci Rep. 2022,12:20550.
Yokoi S, Ito T, Sahashi K, Nakatochi M, Nakamura R, Tohnai G, Fujioka Y, Ishigaki S, Udagawa T, Izumi Y, Morita M, Kano O, Oda M, Sone T, Okano H, Atsuta N, Katsuno M, Okada Y, Sobue G. The SYNGAP1 3'UTR variant in ALS patients causes aberrant SYNGAP1 splicing and dendritic spine loss by recruiting HNRNPK. J Neurosci. 2022 Oct 19:JN-RM-0455-22.
Akihiro Fukushima, Naoya Kataoka, Kazuhiro Nakamura. An oxytocinergic neural pathway that stimulates thermogenic and cardiac sympathetic outflow. Cell Rep. 2022 Sep 20;40(12):111380.
Quan X, Kato D, Daria V, Matoba O, Wake H. Holographic microscope and its biological application. Neurosci Res. 2022 Jun;179:57-64.
Hirata Y, Nomura K, Kato D, Tachibana Y, Niikura T, Uchiyama K, Hosooka T, Fukui T, Oe K, Kuroda R, Hara Y, Adachi T, Shibasaki K, Wake H, Ogawa W.J. A Piezo1/KLF15/IL-6 axis mediates immobilization-induced muscle atrophy. Clin Invest. 2022 Mar 15:e154611.
Murayama M, Wake H. Lighting up cosmic neuronal networks with transformative in vivo calcium imaging. Neurosci Res. 2022 Jun;179:1-2.
Takeda I, Yoshihara K, Cheung DL, Kobayashi T, Agetsuma M, Tsuda M, Eto K, Koizumi S, Wake H, Moorhouse AJ, Nabekura J. Controlled activation of cortical astrocytes modulates neuropathic pain-like behaviour. Nat Commun. 2022 Jul 14;13(1):4100.
Kotaro Sato, Koki Fujii, Noriyuki Yamamoto, Norihisa Ichimura, Satoshi Yamaguchi, Hirohisa Yamada, Hideharu Hibi, Shinya Toyokuni. Association of alcohol intake and female gender with high expression of TMPRSS2 in tongue as potential risk for SARS-CoV-2 infection. J. Clin. Biochem. Nutr. 2022 Sep;71(2):129-135.
Noriaki Gibo, Tomonari Hamaguchi, Yasuo Miki, Takeshi Yamamura, Masato Nakaguro, Mikako Ito, Masanao Nakamuara, Hiroki Kawashima, Masaaki Hirayama, Yoshiki Hirooka, Koichi Wakabayashi, Kinji Ohno. Examination of Abnormal Alpha-synuclein Aggregates in the Enteric Neural Plexus in Patients with Ulcerative Colitis. J Gastrointestin Liver Dis. 2022 Aug 23.
Matsumoto Y, Shinjo K, Mase S, Fukuyo M, Aoki K, Ozawa F, Yoshihara H, Goto S, Kitaori T, Ozaki Y, Takahashi S, Kaneda A, Sugiura-Ogasawara M, Kondo Y. Characteristic DNA methylation profiles of chorionic villi in recurrent miscarriage. Sci Rep. 2022 Jul 27;12(1):11673.
Yuya Hara, Takahiro Watanabe, Masahiro Yoshida, H M Abdullah Al Masud, Hiromichi Kato, Tomohiro Kondo, Reiji Suzuki, Shutaro Kurose, Md Kamal Uddin, Masataka Arata, Shouhei Miyagi, Yusuke Yanagi, Yoshitaka Sato, Hiroshi Kimura, Takayuki Murata . Comprehensive Analyses of Intraviral Epstein-Barr Virus Protein-Protein Interactions Hint Central Role of BLRF2 in the Tegument Network. J Virol. 2022 Jul 27;96(14):e0051822.
Koyo Tsujikawa, Kohei Hamanaka, Yuichi Riku, Yuki Hattori, Norikazu Hara, Yohei Iguchi, Shinsuke Ishigaki, Atsushi Hashizume, Satoko Miyatake, Satomi Mitsuhashi, Yu Miyazaki, Mayumi Kataoka, Li Jiayi, Keizo Yasui, Satoshi Kuru, Haruki Koike, Kenta Kobayashi, Naruhiko Sahara, Norio Ozaki, Mari Yoshida, Akiyoshi Kakita, Yuko Saito, Yasushi Iwasaki, Akinori Miyashita, Takeshi Iwatsubo, Japanese Alzheimer's Disease Neuroimaging Initiative (J-ADNI); Takeshi Ikeuchi, Japanese Longitudinal Biomarker Study in PSP and CBD (JALPAC) Consortium; Takaki Miyata, Gen Sobue, Naomichi Matsumoto, Kentaro Sahashi, Masahisa Katsuno. Actin-binding protein filamin-A drives tau aggregation and contributes to progressive supranuclear palsy pathology. Sci Adv. 2022 May 27;8(21):eabm5029.
Yohei Tsukamoto, Mitsutaka Ogawa, Kentarou Yogi, Yuko Tashima, Hideyuki Takeuchi, Tetsuya Okajima. Glycoproteomics of NOTCH1 EGF repeat fragments overexpressed with different glycosyltransferases in HEK293T cells reveals insights into O-GlcNAcylation of NOTCH1. Glycobiology. 2022 Jun 13;32(7):616-628.
Sota Saeki, Katsuhiro Tokutake, Masaki Takasu, Shigeru Kurimoto, Yuta Asami, Keiko Onaka, Masaomi Saeki and Hitoshi Hirata. Functional Reconstruction of Denervated Muscle by Xenotransplantation of Neural Cells from Porcine to Rat. Int J Mol Sci. 2022 Aug 7;23(15):8773.
Katsuhiro Tokutake, Masaru Takeuchi, Shigeru Kurimoto, Sota Saeki, Yuta Asami, Keiko Onaka, Masaomi Saeki, Tadayoshi Aoyama, Yasuhisa Hasegawa and Hitoshi Hirata. A Therapeutic Strategy for Lower Motor Neuron Disease and Injury Integrating Neural Stem Cell Transplantation and Functional Electrical Stimulation in a Rat Model. Int. J. Mol. Sci. 2022, 23(15), 8760.
Haruki Koike, Soma Furukawa, Naohiro Mouri, Yuki Fukami, Masahiro Iijima and Masahisa Katsuno. Early ultrastructural lesions of anti-neutrophil cytoplasmic antibody- versus complement-associated vasculitis. Neuropathology 2022.
Haruki Koike, Ryoji Nishi, Soma Furukawa, Naohiro Mouri, Yuki Fukami, Masahiro Iijima, Masahisa Katsuno. In vivo visualization of eosinophil secretion in eosinophilic granulomatosis with polyangiitis: An ultrastructural study. Allergol Int. 2022 Jul;71(3):373-382.
Haruki Koike, Soma Furukawa, Naohiro Mouri, Yuki Fukami, Masahiro Iijima, Masahisa Katsuno. Dosage effects of PMP22 on nonmyelinating Schwann cells in hereditary neuropathy with liability to pressure palsies. Neuromuscul Disord. 2022 Jun;32(6):503-511.
Hsueh-Wen Hsueh, Chi-Chao Chao, Koping Chang, Yung-Ming Jeng, Masahisa Katsuno, Haruki Koike, Sung-Tsang Hsieh. Unique Phenotypes With Corresponding Pathology in Late-Onset Hereditary Transthyretin Amyloidosis of A97S vs. V30M. Front Aging Neurosci. 2022 Jan 26;13:786322.
Haruki Koike, Ryoji Nishi, Ken Ohyama, Saori Morozumi, Yuichi Kawagashira, Soma Furukawa, Naohiro Mouri, Yuki Fukami, Masahiro Iijima, Gen Sobue, Masahisa Katsuno. ANCA-Associated Vasculitic Neuropathies: A Review. Neurol Ther. 2022 Mar;11(1):21-38.
Suzuki A, Sakamoto K, Nakahara Y, Enomoto A, Hino J, Ando A, Inoue M, Shiraki Y, Omote N, Kusaka M, Fukihara J, Hashimoto N. BMP3b is a Novel Anti-Fibrotic Molecule Regulated by Meflin in Lung Fibroblasts. Am J Respir Cell Mol Biol. 2022 Jun 21.
Gen S, Tanaka I, Morise M, Koyama J, Kodama Y, Matsui A, Miyazawa A, Hase T, Hibino Y, Yokoyama T, Kimura T, Yoshida N, Sato M, Hashimoto N. Clinical efficacy of osimertinib in EGFR-mutant non-small cell lung cancer with distant metastasis. BMC Cancer 2022 22(1):654.
Segi N, Ozaki T, Suzuki Y, Ouchida J, Imagama S, Kadomatsu K, Sakamoto K. Close association of polarization and LC3, a marker of autophagy, in axon determination in mouse hippocampal neurons. Experimental Neurology 2022;354:114112.
Kazuhisa Kitami, Masato Yoshihara, Satoshi Tamauchi, Mai Sugiyama, Yoshihiro Koya, Yoshihiko Yamakita, Hiroki Fujimoto, Shohei Iyoshi, Kaname Uno, Kazumasa Mogi, Yoshiki Ikeda, Akira Yokoi, Nobuhisa Yoshikawa, Kimihiro Nishino, Kaoru Niimi, Akihiro Nawa, Atsushi Enomoto, Hiroaki Kajiyama. Peritoneal restoration by repurposing vitamin D inhibits ovarian cancer dissemination via blockade of the TGF-β1/thrombospondin-1 axis. Matrix Biol. 2022 May;109:70-90.
Naoki Nishio, Sohei Mitani, Kayo Sakamoto, Gaku Morimoto, Sayaka Yokoi, Mayu Shigeyama, Akihisa Wada, Nobuaki Mukoyama, Eben L. Rosenthal, Michihiko Sone. Validation of a surgical training model containing indocyanine green for near-infrared fluorescence imaging. Laryngoscope Investigative Otolaryngology. 2022;7(4):1011‐1017.
Ito K, Nishida Y, Hamada S, Shimizu K, Sakai T, Ohkawara B, Alman BA, Enomoto A, Ikuta K, Koike H, Zhang J, Ohno K, Imagama S. Efficacy of auranofin as an inhibitor of desmoid progression. Sci Rep. 2022 Jul 13;12(1):11918.
Jozuka R, Kimura H, Uematsu T, Fujigaki H, Yamamoto Y, Kobayashi M, Kawabata K, Koike H, Inada T, Saito K, Katsuno M, Ozaki N. Severe and long-lasting neuropsychiatric symptoms after mild respiratory symptoms caused by COVID-19: A case report. Neuropsychopharmacol Rep 2022, 42, 114-119.
Yoshihiro Ito, Runan Sun, Hiroshi Yagimuma, Keigo Taki, Akira Mizoguchi, Tomoko Kobayashi, Mariko Sugiyama, Takeshi Onoue, Taku Tsunekawa, Hiroshi Takagi, Daisuke Hagiwara, Shintaro Iwama, Hidetaka Suga, Hiroyuki Konishi, Hiroshi Kiyama, Hiroshi Arima, and Ryoichi Banno. Protein Tyrosine Phosphatase 1B Deficiency Improves Glucose Homeostasis in Type 1 Diabetes Treated With Leptin. Diabetes. 2022 Sep 1;71(9):1902-1914.
Tanaka H, Kanda M, Shimizu D, Tanaka C, Inokawa Y, Hattori N, Hayashi M, Nakayama G, Kodera Y. Transcriptomic profiling on localized gastric cancer identified CPLX1 as a gene promoting malignant phenotype of gastric cancer and a predictor of recurrence after surgery and subsequent chemotherapy. J Gastroenterol. 2022 Sep;57(9):640-653.
Yamanaka M, Hayashi M, Sonohara F, Yamada S, Tanaka H, Sakai A, Mii S, Kobayashi D, Kurimoto K, Tanaka N, Inokawa Y, Takami H, Hattori N, Kanda M, Tanaka C, Nakayama G, Koike M, Kodera Y. Downregulation of ROBO4 in Pancreatic Cancer Serves as a Biomarker of Poor Prognosis and Indicates Increased Cell Motility and Proliferation Through Activation of MMP-9. Ann Surg Oncol. 2022 Jun 20.
Sakata K, Kanda M, Shimizu D, Nakamura S, Inokawa Y, Hattori N, Hayashi M, Tanaka C, Nakayama G, Kodera Y. Expression of cellular retinoic acid binding protein 1 predicts peritoneal recurrence of gastric cancer. Int J Oncol. 2022 Jun;60(6):63.
Umeda S, Kanda M, Shimizu D, Nakamura S, Sawaki K, Inokawa Y, Hattori N, Hayashi M, Tanaka C, Nakayama G, Kodera Y. Lysosomal-associated membrane protein family member 5 promotes the metastatic potential of gastric cancer cells. Gastric Cancer. 2022 May;25(3):558-572.
Baba H, Kanda M, Sawaki K, Nakamura S, Ueda S, Shimizu D, Koike M, Kodera Y, Fujii T. SLC7A9 as a Potential Biomarker for Lymph Node Metastasis of Esophageal Squamous Cell Carcinoma. Ann Surg Oncol. 2022 Apr;29(4):2699-2709.
S Takeuchi, T Takeichi, Y Koike, H Takama, K Tanahashi, Y Okuno, N Ishii, Y Muro, T Ogi, Y Suga, M Akiyama. Mutations in SAM syndrome and palmoplantar keratoderma patients suggest genotype/phenotype correlations in DSG1 mutations. J Eur Acad Dermatol Venereol. 2022 Mar;36(3):e215-e218.
Yuta Ozaki, Koji Ohashi, Naoya Otaka, Hayato Ogawa, Hiroshi Kawanishi, Tomonobu Takikawa, Lixin Fang, Minako Tatsumi, Mikito Takefuji, Takashi Enomoto, Mohamed Darwish, Yoko Iijima, Takatoshi Iijima, Toyoaki Murohara, Noriyuki Ouchi. Neuron-derived neurotrophic factor protects against dexamethasone-induced skeletal muscle atrophy. Biochem Biophys Res Commun. 2022 Feb 19;593:5-12.
Lixin Fang, Koji Ohashi, Naoya Otaka, Hayato Ogawa, Mizuho Hiramatsu-Ito, Hiroshi Kawanishi, Yasuko K Bando, Rei Shibata, Yuuki Shimizu, Katsuhiro Kato, Tomonobu Takikawa, Yuta Ozaki, Mikito Takefuji, Toyoaki Murohara, Noriyuki Ouchi. Omentin attenuates angiotensin II-induced abdominal aortic aneurysm formation in apolipoprotein E-knockout mice. Cardiovasc Res. 2022 May 6;118(6):1597-1610.
Yukie Yamahashi, You-Hsin Lin, Akihiro Mouri, Sho Iwanaga, Kazuhiro Kawashima, Yuya Tokumoto, Yo Watanabe, Md. Omar Faruk, Xinjian Zhang, Daisuke Tsuboi, Takashi Nakano, Naoaki Saito, Taku Nagai, Kiyofumi Yamada, Kozo Kaibuchi. Phosphoproteomic of the acetylcholine pathway enables discovery of the PKC-β-PIX-Rac1-PAK cascade as a stimulatory signal for aversive learning. Mol Psychiatry. 2022 Jun 3.
Mengya Wu, Yasuhiro Funahashi, Tetsuya Takano, Emran Hossen, Rijwan Uddin Ahammad, Daisuke Tsuboi, Mutsuki Amano, Kiyofumi Yamada, Kozo Kaibuchi. Rho-Rho-Kinase Regulates Ras-ERK Signaling Through SynGAP1 for Dendritic Spine Morphology. Neurochem Res. 2022 May 27.
Mutsuki Amano, Yoko Kanazawa, Kei Kozawa, Kozo Kaibuchi. Identification of the Kinase-Substrate Recognition Interface between MYPT1 and Rho-Kinase. Biomolecules. 2022 Jan 18;12(2):159.
Md Omar Faruk, Daisuke Tsuboi, Yukie Yamahashi, Yasuhiro Funahashi, You-Hsin Lin, Rijwan Uddin Ahammad, Emran Hossen, Mutsuki Amano, Tomoki Nishioka, Anastasios V Tzingounis, Kiyofumi Yamada, Taku Nagai, Kozo Kaibuchi. Muscarinic signaling regulates voltage-gated potassium channel KCNQ2 phosphorylation in the nucleus accumbens via protein kinase C for aversive learning. J Neurochem. 2022 Feb;160(3):325-341.
Miyake N, Nagai T, Suga H, Osuka S, Kasai T, Sakakibara M, Soen M, Ozaki H, Miwata T, Asano T, Kano M, Muraoka A, Nakanishi N, Nakamura T, Goto M, Yasuda Y, Kawaguchi Y, Miyata T, Kobayashi T, Sugiyama M, Onoue T, Hagiwara D, Iwama S, Iwase A, Inoshita N, Arima H, Kajiyama H. Functional Lactotrophs in Induced Adenohypophysis Differentiated From Human iPS Cells. Endocrinology. 2022;163(3):bqac004.
Keiji Hasebe, Kimitoshi Yamazaki, Junpei Yamaguchi, Toshio Kokuryo, Yukihiro Yokoyama, Kazushi Miyata, Masahide Fukaya, Masato Nagino, Tomoki Ebata. Trefoil factor 1 inhibits the development of esophageal adenocarcinoma from Barrett's epithelium. Lab Invest. 2022 Aug;102(8):885-895.
Yuko Shimamura, Kazuhiro Furuhashi, Akihito Tanaka, Munetoshi Karasawa, Tomoya Nozaki, Shintaro Komatsu, Kenshi Watanabe, Asuka Shimizu, Shun Minatoguchi, Makoto Matsuyama, Yuriko Sawa, Naotake Tsuboi, Takuji Ishimoto, Hiroshi I. Suzuki & Shoichi Maruyama. Mesenchymal stem cells exert renoprotection via extracellular vesicle-mediated modulation of M2 macrophages and spleen-kidney network. Commun Biol 5, 753 (2022).
Vijayashree Mysore, Suhail Tahir, Kazuhiro Furuhashi, Jatin Arora, Florencia Rosetti, Xavier Cullere, Pascal Yazbeck, Miroslav Sekulic, Madeleine E. Lemieux, Soumya Raychaudhuri, Bruce H. Horwitz, Tanya N. Mayadas. Monocytes transition to macrophages within the inflamed vasculature via monocyte CCR2 and endothelial TNFR2. J Exp Med (2022) 219 (5): e20210562.
Shun Minatoguchi, Shoji Saito, Kazuhiro Furuhashi, Yuriko Sawa, Masaki Okazaki, Yuko Shimamura, Ahmad Baseer Kaihan, Yusaku Hashimoto, Yoshinari Yasuda, Akitoshi Hara, Yasuyuki Mizutani, Ryota Ando, Noritoshi Kato, Takuji Ishimoto, Naotake Tsuboi, Nobutoshi Esaki, Makoto Matsuyama, Yukihiro Shiraki, Hiroki Kobayashi, Naoya Asai, Atsushi Enomoto & Shoichi Maruyama. A novel renal perivascular mesenchymal cell subset gives rise to fibroblasts distinct from classic myofibroblasts. Sci Rep 12, 5389 (2022).
Keisuke Oka, Nobuyuki Tetsuka, Hiroshi Morioka, Mitsutaka Iguchi, Kazumitsu Kawamura, Kengo Hayashi, Takako Yanagiya, Yuiko Morokuma, Tomohisa Watari, Makiko Kiyosuke, Tetsuya Yagi. Genetic and epidemiological analysis of ESBL-producing Klebsiella pneumoniae in three Japanese university hospitals. J Infect Chemother. 2022 Sep;28(9):1286-1294.
Hattori Y, Kato D, Murayama F, Koike S, Naito Y, Kawaguchi A, Wake H, Miyata T. Border-associated macrophages transventricularly infiltrate the early embryonic cerebral wall to differentiate into microglia. bioRxiv.
Hattori Y, Itoh H, Tsugawa Y, Nishida Y, Kurata K, Uemura A, Miyata T. Embryonic pericytes promote microglial homeostasis and their effects on neural progenitors in the developing cerebral cortex. J Neurosci. 2022 Jan 19;42(3):362-376.
Sumiko Kiryu-Seo, Reika Matsushita, Yoshitaka Tashiro, Takeshi Yoshimura, Yohei Iguchi, Masahisa Katsuno, Ryosuke Takahashi, Hiroshi Kiyama. Impaired disassembly of the axon initial segment restricts mitochondrial entry into damaged axons. The EMBO Journal (2022)e110486.
Nakamura K & Morrison S. F. Central sympathetic network for thermoregulatory responses to psychological stress. Auton. Neurosci. 237:102918, 2022.
Nakamura K, Nakamura Y & Kataoka N. A hypothalamomedullary network for physiological responses to environmental stresses. Nature Rev. Neurosci. 23 (1):35-52, 2022.
Naoki Segi, Tomoya Ozaki, Yuji Suzuki, Jun Ouchida, Shiro Imagama, Kenji Kadomatsu, Kazuma Sakamoto. Close association of polarization and LC3, a marker of autophagy, in axon determination in mouse hippocampal neurons. Experimental Neurology 354 (2022) 11.
Iida T, Mizutani Y, Esaki N, Ponik SM, Burkel BM, Weng L, Kuwata K, Masamune A, Ishihara S, Haga H, Kataoka K, Mii S, Shiraki Y, Ishikawa T, Ohno E, Kawashima H, Hirooka Y, Fujishiro M, Takahashi M, Enomoto A. Pharmacologic conversion of cancer-associated fibroblasts from a protumor phenotype to an antitumor phenotype improves the sensitivity of pancreatic cancer to chemotherapeutics. Oncogene. 2022 May;41(19):2764-2777.
Ryosuke Ichihara, Yukihiro Shiraki, Yasuyuki Mizutani, Tadashi Iida, Yuki Miyai, Nobutoshi Esaki, Akira Kato, Shinji Mii, Ryota Ando, Masamichi Hayashi, Hideki Takami, Tsutomu Fujii, Masahide Takahashi, Atsushi Enomoto. Matrix remodeling-associated protein 8 is a marker of asubset of cancer-associated fibroblasts in pancreatic cancer. Pathology International. 2022;72:161-175.
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Suzuki K, Okuno Y, Kawashima N, Muramatsu H, Okuno T, Wang X, Kataoka S, Sekiya Y, Hamada M, Murakami N, Kojima D, Narita K, Narita A, Sakaguchi H, Sakaguchi K, Yoshida N, Nishio N, Hama A, Takahashi Y, Kudo K, Kato K, Kojima S. MEF2D-BCL9 Fusion Gene Is Associated With High-Risk Acute B-Cell Precursor Lymphoblastic Leukemia in Adolescents. J Clin Oncol. 2016 Oct 1;34(28):3451-9.
Kojima D, Muramatsu H, Okuno Y, Kataoka S, Murakami N, Tanahashi Y, Suzuki K, Kato T, Sekiya Y, Kawashima N, Narita A, Nishio N, Hama A, Imai K, Nonoyama S, Takahashi Y, Kojima S. Successful T-cell reconstitution after unrelated cord blood transplantation in a patient with complete DiGeorge syndrome. J Allergy Clin Immunol. 2016 Nov;138(5):1471-1473.e4.
Kojima D, Wang X, Muramatsu H, Okuno Y, Nishio N, Hama A, Tsuge I, Takahashi Y, Kojima S. Application of extensively targeted next-generation sequencing for the diagnosis of primary immunodeficiencies. J Allergy Clin Immunol. 2016 Jul;138(1):303-305.e3.
Wu H, Cheng XW, Hu L, Takeshita K, Chen H, Du Q, Li X, Zhu E, Huang Z, Yisireyili M, Zhao G, Piao L, Inoue A, Jiang H, Lei Y, Zhang X, Liu S, Dai Q, Kuzuya M, Shi GP, and Murohara T. Cathepsin S Activity Controls Injury-Related Vascular Repair in Mice via the p38MAPK and PI3K-Akt/p-HDAC6 Signaling Pathway. Arteriosclerosis, Thromobosis, and Vascular Biology. 2016Aug1;36(8):1549-1557.
Shiho Kondo, et al, Functional characteristics of L1156F-CFTR associated with alcoholic chronic pancreatitis in Japanese. Pancreatic Physiology/Pathophysiology 2015 Aug 15;309(4):G260-9
Yamashita K, Nagai H, Toyokuni S. Receptor role of the annexin A2 in the mesothelial endocytosis of crocidolite fibers. Laboratory investigation; a journal of technical methods and pathology 2015, 95, 749-764.
Rahman M. A, Azuma Y, Nasrin F, Takeda J, Nazim M, Bin Ahsan K, Masuda A, Engel A. G, Ohno K. SRSF1 and hnRNP H antagonistically regulate splicing of COLQ exon 16 in a congenital myasthenic syndrome. Scientific reports 2015, 5, 13208.
Ohkawa Y, Momota H, Kato A, Hashimoto N, Tsuda Y, Kotani N, Honke K, Suzumura A, Furukawa K, Ohmi Y, Natsume A, Wakabayashi T, Furukawa K. Ganglioside GD3 Enhances Invasiveness of Gliomas by Forming a Complex with Platelet-derived Growth Factor Receptor α and Yes Kinase. The Journal of biological chemistry 2015, 290, 16043-16058.
Kiyota A, Iwama S, Sugimura Y, Takeuchi S, Takagi H, Iwata N, Nakashima K, Suzuki H, Nishioka T, Kato T, Enomoto A, Arima H, Kaibuchi K, Oiso Y. Identification of the novel autoantigen candidate Rab GDP dissociation inhibitor alpha in isolated adrenocorticotropin deficiency. Endocr J 2015, 62, 153-160.
Iwama S, Sugimura Y, Kiyota A, Kato T, Enomoto A, Suzuki H, Iwata N, Takeuchi S, Nakashima K, Takagi H, Izumida H, Ochiai H, Fujisawa H, Suga H, Arima H, Shimoyama Y, Takahashi M, Nishioka H, Ishikawa S. E, Shimatsu A, Caturegli P, Oiso Y. Rabphilin-3A as a Targeted Autoantigen in Lymphocytic Infundibulo-neurohypophysitis. The Journal of clinical endocrinology and metabolism 2015, 100, E946-954.
Chen D, Ito S, Yuan H, Hyodo T, Kadomatsu K, Hamaguchi M, Senga T. EML4 promotes the loading of NUDC to the spindle for mitotic progression. Cell cycle 2015, 14, 1529-1539.
Tamada H, Kiyama H. Existence of c-Kit negative cells with ultrastructural features of interstitial cells of Cajal in the subserosal layer of the W/Wv mutant mouse colon.J Smooth Muscle Res 51; pp1-9 (2015)
YUMIKO YAMAMURA, NAOYA ASAI, ATSUSHI ENOMOTO, TAKUYA KATO, SHINJI MII, YUJI KONDO, KAORI USHIDA, KAORU NIIMI, NOBUYUKI TSUNODA, MASATO NAGINO, SHU ICHIHARA, KOICHI FURUKAWA, KENGO MAEDA, TOYOAKI MUROHARA, AND MASAHIDE TAKAHASHI. AKT-GIRDIN SIGNALING IN CANCER-ASSOCIATED FIBROBLASTS CONTRIBUTES TO TUMOR PROGRESSION. CANCER RES. 2015 MAR 1;75(5):813-23.
Ito S, Tanaka Y, Oshino R, Aiba K, Thanasegaran S, Nishio N, Isobe K. GADD34 inhibits activation-induced apoptosis of macrophages through enhancement of autophagy. Sci Rep, 2015;5:8327.
Okabe M, Ito S, Nishio N, Tanaka Y, Isobe K. Thymic Epithelial Cells Induced from Pluripotent Stem Cells by a Three-Dimensional Spheroid Culture System Regenerates Functional T Cells in Nude Mice. Cell Reprogram, 2015;17:368-375.
Liu L, Ito S, Nishio N, Sun Y, Chen N, Tanaka Y, Isobe K. GADD34 Facilitates Cell Death Resulting from Proteasome Inhibition. Anticancer Res, 2015;35:5317-5324.
Tanaka Y, Ito S, Oshino R, Chen N, Nishio N, Isobe K. Effects of growth arrest and DNA damage-inducible protein 34 (GADD34) on inflammation-induced colon cancer in mice. Br J Cancer, 2015;113:669-679.
Okuno Y, Hoshino A, Muramatsu H, Kawashima N, Wang X, Yoshida K, Wada T, Gunji M, Toma T, Kato T, Shiraishi Y, Iwata A, Hori T, Kitoh T, Chiba K, Tanaka H, Sanada M, Takahashi Y, Nonoyama S, Ito M, Miyano S, Ogawa S, Kojima S, Kanegane H. Late-Onset Combined Immunodeficiency with a Novel IL2RG Mutation and Probable Revertant Somatic Mosaicism. J Clin Immunol. 2015 Oct;35(7):610-4.
Wang X, Muramatsu H, Okuno Y, Sakaguchi H, Yoshida K, Kawashima N, Xu Y, Shiraishi Y, Chiba K, Tanaka H, Saito S, Nakazawa Y, Masunari T, Hirose T, Elmahdi S, Narita A, Doisaki S, Ismael O, Makishima H, Hama A, Miyano S, Takahashi Y, Ogawa S, Kojima S. GATA2 and secondary mutations in familial myelodysplastic syndromes and pediatric myeloid malignancies. Haematologica. 2015 Oct;100(10):e398-401.