Welcome to the Department of Integrative Physiology at Nagoya University!

Our research focuses on fundamental brain mechanisms for homeostasis.

What's New!

September 18, 2024: Kazu Nakamura's book chapter "Central mechanisms of thermoregulation and fever in mammals" was published in Thermal Biology (Springer Nature). This review chapter provides an update on the brain circuit mechanisms of body temperature regulation and fever, including our research results.
April 10, 2024: Our research discovery on the mechanism of middle-age obesity was featured in an article of BBC Science Focus.
April 1, 2024: Dr. Yuji Suzuki joined our lab as an Assistant Professor.
March 25, 2024: Dr. Takaki Yahiro received his Ph.D. degree. Congratulations!!
March 7, 2024: Manami Oya's first author paper "Age-related ciliopathy: Obesogenic shortening of melanocortin-4 receptor-bearing neuronal primary cilia" was published online in Cell Metabolism. We discovered that the anti-obesity receptor molecule MC4R localizes to primary cilia of hypothalamic neurons and that these cilia shorten with age, providing a fundamental mechanism of age-related obesity (middle-aged obesity). This paper was press-released from Nagoya University (link) and EurekAlert! (link) and summarized in the website of the Physiological Society of Japan (link).
February 1, 2024: Akihiro Fukushima was promoted to Designated Senior Lecturer.
June 20, 2023: Takaki Yahiro's first author paper "Two Ascending Thermosensory Pathways from the Lateral Parabrachial Nucleus That Mediate Behavioral and Autonomous Thermoregulation" was published online in The Journal of Neuroscience. This study investigated the roles of two central thermosensory afferent neural pathways in behavioral and autonomous thermoregulation and revealed a new thermoregulatory role of the amygdala, which may contribute to the induction of comfort and discomfort by temperature sensations. This paper was press-released from Nagoya University (link) and EurekAlert! (link).
April 12, 2023: Takaki Yahiro's first author preprint "Two Ascending Thermosensory Pathways from the Lateral Parabrachial Nucleus That Mediate Behavioral and Autonomous Thermoregulation" was posted on bioRxiv (Online published in The Journal of Neuroscience on June 20, 2023).
April 12, 2023: The co-authoring paper "Sleep–wake patterns are altered with age, Prdm13 signaling in the DMH, and diet restriction in mice" (co-authoring with Dr. Akiko Satoh at Tohoku University & National Center for Geriatrics and Gerontology) was published in Life Science Alliance.
March 20, 2023: Takaki Yahiro received the Physiological Reports Poster Award at the 100th Anniversary Annual Meeting of the Physiological Society of Japan.
March 8, 2023: Our paper "Central efferent pathways for cold-defensive and febrile shivering" published in 2011 has been selected among the most influential 40 papers published by Japanese authors in the Journal of Physiology, and listed in the journal's Virtual Issue celebrating the Physiological Society of Japan's 100th Anniversary.
February 20, 2023: Takaki Yahiro received the Poster Presentation Award at the 4th CIBoG Retreat.
January 26, 2023: The co-authoring paper "The neural pathway of the hyperthermic response to antagonists of the transient receptor potential vanilloid-1 channel" (co-authoring with Dr. Andras Garami at University of Pécs, Dr. Shaun Morrison at Oregon Health & Science University, and Dr. Andrej Romanovsky at St. Joseph’s Hospital and Medical Center) was published in Temperature.
December 23, 2022: Yoshiko Nakamura's first author paper "Prostaglandin EP3 receptor–expressing preoptic neurons bidirectionally control body temperature via tonic GABAergic signaling" was published in Science Advances. This study identified a group of "master neurons" for body temperature regulation in mammals. We revealed that continuous inhibitory (GABAergic) signaling from these neurons is a fundamental determinant of body temperature for thermal homeostasis and fever. This paper was press-released from Nagoya University (link) and EurekAlert! (link).
September 20, 2022: Akihiro Fukushima's first author paper "An oxytocinergic neural pathway that stimulates thermogenic and cardiac sympathetic outflow" was published in Cell Reports. This study revealed a novel brain neural pathway through which the "love hormone" oxytocin promotes heat production in brown adipose tissue. This mechanism is expected to be a new target for prevention and treatment of obesity. This paper was press-released from Nagoya University (link) and summarized in the website of the Physiological Society of Japan (link).
August 29, 2022: The co-authoring paper "A brainstem monosynaptic excitatory pathway that drives locomotor activities and sympathetic cardiovascular responses" (collaboration with Dr. Satoshi Koba and Prof. Tatsuo Watanabe) was published in Nature Communications. This study discovered a central command mechanism for blood pressure control during locomotion.
June 7, 2022: The co-authoring paper "Coagulation factors promote brown adipose tissue dysfunction and abnormal systemic metabolism in obesity" (collaboration with Drs. Ippei Shimizu and Tohru Minamino at Juntendo University) was published in iScience.
April 17, 2022: Yoshiko Nakamura's first author preprint "Prostaglandin EP3 receptor-expressing preoptic neurons bidirectionally control body temperature via tonic GABAergic signaling" was posted on bioRxiv. This study identified a group of neurons in the preoptic area of hypothalamus that bidirectionally controls body temperature by using the inhibitory neurotransmitter GABA.
February 20, 2022: The commentary "Thermoregulation in mice: The road to understanding torpor hypothermia and the shortcomings of a circuit for generating fever" (co-authoring with Dr. Shaun Morrison at Oregon Health & Science University) was published in Temperature.
December 1, 2021: Ms. Yuko Furukawa joined our lab as a technical staff.
November 18, 2021: Kazu Nakamura published with Dr. Shaun Morrison (Oregon Health & Science University) a review article "Central sympathetic network for thermoregulatory responses to psychological stress" in Autonomic Neuroscience. This article presents recent research advances in understanding the central circuit mechanisms for physiological responses to psychological stress.
November 2, 2021: Kazu Nakamura, Yoshiko Nakamura and Naoya Kataoka published a perspective review article "A hypothalamomedullary network for physiological responses to environmental stresses" in Nature Reviews Neuroscience. This article presents a unified model of the central neural circuit for physiological responses to a variety of environmental stresses, which is essential to sustain our life under variably changing environments.
July 27, 2021: The book chapter "Efficient labeling of neurons and identification of postsynaptic sites using adeno-associated virus vector" (co-authoring with Dr. Hiroyuki Hioki at Juntendo University) was published in Neuromethods. This chapter provides our detailed protocol for production and purification of adeno-associated virus useful in neuroscientific research.
June 1, 2021: Ms. Misako Takemoto joined our lab as a technical staff.
May 4, 2021: The collaborative paper "Metabolic flexibility via mitochondrial BCAA carrier SLC25A44 is required for optimal fever" (collaboration with Dr. Takeshi Yoneshiro at Tokyo University and Dr. Shingo Kajimura at Beth Israel Deaconess Medical Center / Harvard Medical School) was published in eLife.
April 14, 2021: Kazu Nakamura received the Award for Science and Technology (Research Category) as the Commendation for Science and Technology by the Minister of Education, Culture, Sports, Science and Technology.
April 1, 2021: Manami Oya was promoted to Assistant Professor.
March 27, 2021: Naoya Kataoka received the 22nd Promotion Award of the Physiological Society of Japan.
February 16, 2021: The co-authoring paper "microRNA-33 maintains adaptive thermogenesis via enhanced sympathetic nerve activity" (collaboration with Drs. Takahiro Horie and Koh Ono at Kyoto University) was published in Nature Communications.
October 21, 2020: A short article on our discovery of the mind-body connection in the brain, "Where mind meets body: a master brain circuit for stress responses" was published in The Science Breaker.
July 2, 2020: The co-authoring paper "Combi-CRISPR: combination of NHEJ and HDR provides efficient and precise plasmid-based knock-ins in mice and rats" (collaboration with Prof. Tomoji Mashimo at Tokyo University) was published in Human Genetics.
May 5, 2020: Our research published in Science was featured in a story of a Forbes article.
May 1, 2020: Yoshiko Nakamura was promoted to Senior Lecturer and Naoya Kataoka was promoted to Designated Senior Lecturer.
April 1, 2020: Ms. Hiroko Wakabayashi joined our lab as a secretary.
March 6, 2020: Naoya Kataoka's first author paper "A central master driver of psychosocial stress responses in the rat" was published in Science (Free access to full manuscript from HERE). This paper was press-released from Nagoya University (link1, link2) and received media coverage (see a brief summary in PSJ and commentaries in Nature and Nature Reviews Neuroscience; EurekAlert!).
December 4, 2019: Kazu Nakamura was selected as a Visiting Fellow of the Institute of Advanced Studies at the University of Bologna, Italy, and stayed in the university for one month to give lectures, perform experiments and make international interactions.
March 6, 2019: The co-authoring paper "Involvement of TRPM2 and TRPM8 in temperature-dependent masking behavior" (collaboration with Dr. Wataru Ota and Prof. Takashi Yoshimura) was published in Scientific Reports.
November 17, 2018: Kazu Nakamura's book chapter "Afferent pathways for autonomic and shivering thermoeffectors" was published in Handbook of Clinical Neurology.
October 25, 2018: Yoshiko Nakamura received 2018 Annual Award of Japan Society of Neurovegetative Research for the Best Articles and gave an award lecture at the 71st annual meeting of the society (Saitama, Japan).
September 26, 2018: The co-authoring review article "Central mechanisms for thermoregulation" (with Prof. Shaun Morrison) is to be published in Annual Review of Physiology.
July 17, 2018: The co-authoring paper "Sympathoexcitation by hypothalamic paraventricular nucleus neurons projecting to the rostral ventrolateral medulla" (collaboration with Dr. Satoshi Koba and Prof. Tatsuo Watanabe) was published in Journal of Physiology.
June 4, 2018: Kazu Nakamura's review article "Hunger and satiety signaling: Modeling two hypothalamomedullary pathways for energy homeostasis" was published in BioEssays (online). This article is available for free (PDF).
April 2, 2018: Dr. Akihiro Fukushima (Designated Assistant Professor) joined our lab.
April 1, 2018: Kazu Nakamura joined the Editorial Board of Physiological Reviews, which is the most renowned review journal in physiology.
December 5, 2017: Yoshiko Nakamura's review article "Central regulation of brown adipose tissue thermogenesis and energy homeostasis dependent on food availability" was published in Pflügers Archiv - European Journal of Physiology (online). Anyone can read this article for free (PDF).
September 2, 2017: Symposium "Infection fever, neurogenic fever and psychogenic fever: how are they different?" (organized by Kazuhiro Nakamura & Kiyoshi Matsumura) was held at the Congress of the International Society for Autonomic Neuroscience (ISAN) 2017. Many thanks to the speakers and big audience!
September 1, 2017: Yoshiko Nakamura was awarded "The Professor Geoffrey Burnstock Awards for Young Investigators" at the Congress of the International Society for Autonomic Neuroscience (ISAN) 2017.
July 10, 2017: Takaki Yahiro's first author paper "The lateral parabrachial nucleus, but not the thalamus, mediates thermosensory pathways for behavioural thermoregulation" was published in Scientific Reports (online). This paper was press-released by Nagoya University (link1 link2) and received media coverage (Science Newsline, EurekAlert!).
January 5, 2017: Yoshiko Nakamura's first author paper "Medullary Reticular Neurons Mediate Neuropeptide Y-Induced Metabolic Inhibition and Mastication" was published in Cell Metabolism. This paper was press-released by Nagoya University (link1 link2) and received media coverage (Science Daily, Asahi Shimbun newspaper).
December 20, 2016: The co-authoring paper "Differential Inputs to the Perisomatic and Distal-Dendritic Compartments of VIP-Positive Neurons in Layer 2/3 of the Mouse Barrel Cortex" (collaboration with Dr. Jaerin Sohn and Dr. Hiroyuki Hioki) was published in Frontiers in Neuroanatomy.
May 27, 2016: Kazu Nakamura was invited to the Wenner-Gren Foundations International Symposium "Brown adipose tissue and euthermia" (Stockholm, Sweden) and gave a lecture "Central pathways for cold-induced thermogenesis".
May 20, 2016: Prof. Larry Crawshaw (invited from Portland State University) gave a lacture "Temperature Regulation: Laboratory Experiments and Wilderness Rescue" at the Graduate School of Medicine.
April 1, 2016: Ms. Manami Oya (Post-doctoral Researcher) and Mizuna Tanaka (Technical staff) joined our lab.
March 24, 2016: Symposium "Thermal biology: critical interaction between temperature and life" (organized by Kazuhiro Nakamura & Makoto Tominaga) was held at the 93rd Annual Meeting of the Physiological Society of Japan as a joint symposium with the Japan Neuroscience Society. Many thanks to the speakers and big audience!
March 10, 2016: Kazu Nakamura's co-authoring paper "Dapagliflozin, a sodium-glucose co-transporter 2 inhibitor, acutely reduces energy expenditure in BAT via neural signals in mice" (collaboration with Dr. Tetsuya Yamada and Dr. Hideki Katagiri) was published in PLoS One.
February 18, 2016: Naoya Kataoka has been selected as the recipient of the 20th Yas Kuno Memorial Award.
February 17, 2016: Ms. Tomoko Nagai joined our lab as a secretary.
February 1, 2016: Naoya Kataoka was promoted to Assistant Professor.
November 24, 2015: Kazu Nakamura was invited as a Selection Board member to the APS Select of the American Physiological Society, which selects and highlights exceptional original papers published in the 10 research journals of the society every month.
October 12, 2015: Review article "Neural circuit for psychological stress-induced hyperthermia" was published in Temperature.
October 5, 2015: The article to introduce our study related to 11th JSPS Prize and the Japan Academy Medal Prize" was published in JSPS Quarterly.
June 29, 2015: Our proposal of a new innovative research area "Integrative understanding of biological phenomena with temperature as a key theme (Chief PI: Prof. Makoto Tominaga, NIPS)" has been selected for 5-year support by Grant-in-Aid for Scientific Research on Innovative Areas from the MEXT of Japan.
April 15, 2015: The article "Dr. Kazuhiro Nakamura Awarded the Japan Academy Medal Prize" was published in Research Activities, a public relations magazine from Kyoto University.
April 1, 2015: Kazu Nakamura, Yoshiko Nakamura and Naoya Kataoka moved to Nagoya University Graduate School of Medicine.
February 24, 2015: Kazu Nakamura received the 11th JSPS Prize and the 11th Japan Academy Medal Prize. The prize ceremony was held at the Japan Academy in the presence of Their Imperial Highnesses Prince and Princess Akishino.
January 13, 2015: Kazu Nakamura was selected as a recipient of the 11th Japan Academy Medal Prize. Six recipients were selected from among the annual 25 recipients of the JSPS Prize (Japan Academy website).
December 19, 2014: Kazu Nakamura was selected as a recipient of the 11th JSPS Prize, which is regarded as one of the Japanese government's highest honors for young scientists (JSPS website).
December 5, 2014: Kazu Nakamura was invited by Linköping university in Sweden and served as an opponent for a doctoral defense.
August 22, 2014: A summary of the paper "Psychological stress activates a dorsomedial hypothalamus–medullary raphe circuit driving brown adipose tissue thermogenesis and hyperthermia" published in Cell Metabolism was published on the Science Topics at the website of the Physiological Society of Japan (link).
June 27, 2014: Naoya Kataoka's first author paper "Psychological stress activates a dorsomedial hypothalamus–medullary raphe circuit driving brown adipose tissue thermogenesis and hyperthermia" was published in Cell Metabolism (online). This paper was press-released by Cell Press (link) and received media coverage.
June 26, 2014: Kazu Nakamura's review article "Afferent neural pathways that transmit environmental thermosensory information for body temperature regulation" was published in The Autonomic Nervous System.
May 4, 2014: Battuvshin Lkhagvasuren's first author paper "Distribution of Fos-immunoreactive cells in rat forebrain and midbrain following social defeat stress and diazepam treatment" was published in Neuroscience (online).
April 27, 2014: Kazu Nakamura was awarded the 2014 Henry Pickering Bowditch Award from the American Physiological Society and gave the Bowditch Award Lecture at Experimental Biology 2014 meeting in San Diego. This award is regarded as one of the society's highest honors (see press release from the society).
March 16, 2014: Symposium "Central circuitries for psychologically induced physiological behaviors and responses" (organized by Kazuhiro Nakamura & Takatoshi Hikida) was held at the 91st Annual Meeting of the Physiological Society of Japan as a joint symposium with the Japan Neuroscience Society. Many thanks to the speakers and big audience!
February 4, 2014: Kazu Nakamura's co-authoring paper "Critical roles of nardilysin in the maintenance of body temperature homoeostasis" (collaboration with Dr. Eiichiro Nishi) was published in Nature Communications.
February 1, 2014: Kazu Nakamura was promoted to Associate Professor at the Career-Path Promotion Unit for Young Life Scientists, Kyoto University.
December 21, 2013: Kazu Nakamura joined the Editorial Board of Temperature as a Section Editor on the invitation of the journal.
November 18, 2013: Prof. Shaun Morrison (invited from Oregon Health & Science University) gave a seminar "CNS Pathways Regulating the Sympathetic Outflow to Brown Adipose Tissue (BAT)".
October 31, 2013: The American Physiological Society has selected Kazu Nakamura as the recipient of the 2014 Henry Pickering Bowditch Award. This award is regarded as one of the society's highest honors. Kazu Nakamura will give the Bowditch Award Lecture at Experimental Biology 2014 meeting in San Diego in April 2014.
October 24, 2013: Kazu Nakamura received 2013 Annual Award of Japan Society of Neurovegetative Research for the Best Articles and gave an award lecture at the 66th annual meeting of the society (Nagoya, Japan).
October 1, 2013: Kazu Nakamura's research proposal was accepted by PRESTO of the Japan Science and Technology Agency (Japanese governmental funding).
September 5-6, 2013: "Thermal Physiology Meeting 2013" (organized by Kazuhiro Nakamura & Makoto Tominaga) was held at the National Institute for Physiological Sciences (Okazaki, Aichi). Many thanks to the participants!
August 24, 2013: Naoya Kataoka received a Young Investigator Poster Award at the 18th Adiposcience Symposium (Osaka, Japan).
August 3, 2013: Second-grade students of Kokura High School from Fukuoka visited our laboratory to listen to a lecture and to experience microscopy.
July 19, 2013: Yoshiko Nakamura received a Young Investigator Presentation Award at FASEB Summer Research Conferences "Neural Mechanisms in Cardiovascular Regulation" (Oregon, USA).
April 11, 2013: Kazu Nakamura joined the Editorial Board of Physiological Reports on the invitation of the journal.
April 1, 2013: Kazu Nakamura was promoted to Senior Lecturer at the Career-Path Promotion Unit for Young Life Scientists, Kyoto University.
March 27, 2013: Symposium "Optogenetics marks a new era of in vivo physiology" (organized by Kazuhiro Nakamura & Akihiro Yamanaka) was held at the 90th Annual Meeting of the Physiological Society of Japan as a joint symposium with the Japan Neuroscience Society. Many thanks to the speakers and big audience!
November 1, 2012: Summary of the symposium "Update on brown adipose tissue functions and their mechanisms" (organized by Kazuhiro Nakamura & Masayuki Saito) at the 89th Annual Meeting of the Physiological Society of Japan was published in the SYMPOSIUM section of Journal of the Physiological Society of Japan.
September 22, 2012: Kazu Nakamura's review article (in Japanese) "Central mechanism for regulation of brown fat thermogenesis to survive cold, infection and stress" was published in Journal of Clinical and Experimental Medicine (IGAKU NO AYUMI).
September 21, 2012: Symposium "Various temperature environments affect neuronal activity" (organized by Koji Shibasaki & Kazuhiro Nakamura) was held at the 35th Annual Meeting of the Japan Neuroscience Society (Neuroscience 2012). Many thanks to the speakers and big audience!
September 4-5, 2012: "Thermal Physiology Meeting 2012" (organized by Kazuhiro Nakamura & Makoto Tominaga) was held at the National Institute for Physiological Sciences. Many thanks to the participants!
September 2, 2012: We exhibited an interpretive poster on our research at the outreach event, Kyoto University Academic Day.
June 1, 2012: Kazu Nakamura's illustrated review article (in Japanese) was published in Japanese Journal of Clinical Medicine.
April 17, 2012: Kazu Nakamura received the Young Scientists' Award as the Commendation for Science and Technology by the Minister of Education, Culture, Sports, Science and Technology.
April 2, 2012: Dr. Shingo Kajimura (invited from UCSF Diabetes Center and Department of Cell Tissue Biology) gave a seminar "Engineering Fat Cell Fate: Transcriptional Control of Brown Fat Development".
March 30, 2012: Symposium "Update on brown adipose tissue functions and their mechanisms" (organized by Kazuhiro Nakamura & Masayuki Saito) was held at the 89th Annual Meeting of the Physiological Society of Japan. Many thanks to the speakers and big audience!
January 8, 2012: Kazu Nakamura contributed to an article in The Mainichi Shougakusei Shimbun (National Newspaper for Elementary School Students).
November 29, 2011: Our discovery of the central mechanism for shivering was taken up by Physiology News of the Physiological Society (U.K.). (PDF, page 21)
November 11, 2011: Kazu Nakamura's review article "Central circuitries for body temperature regulation and fever" was featured at "Editor's Choice" on the website of American Journal of Physiology.
October 27–30, 2011: Kazu Nakamura participated in the Japanese-German Frontiers of Science Symposium (JGFoS2011) on the invitation from the Japan Society for the Promotion of Science.
October 6, 2011: Battuvshin Lkhagvasuren's (graduate student) first author paper "Social defeat stress induces hyperthermia through activation of thermoregulatory sympathetic premotor neurons in the medullary raphe region" was published in Europen Journal of Neuroscience (online).
October 6, 2011: Kazu Nakamura taught a class at Kozu High School (Osaka) as a science outreach activity.
September 7, 2011: Kazu Nakamura's review article "Central circuitries for body temperature regulation and fever" was published in American Journal of Physiology (online) on the invitation from American Physiological Society (peer-reviewed).
August 25, 2011: Kazu Nakamura's review article (in Japanese) was published in Journal of Japan Society for the Study of Obesity.
July 29, 2011: Yoshiko Nakamura and Kazu Nakamura's co-authoring paper "EP₃ receptors mediate PGE₂-induced hypothalamic paraventricular nucleus excitation and sympathetic activation" was published in American Journal of Physiology (online).
July 15, 2011: Kazu Nakamura's first-author paper "Central efferent pathways for cold-defensive and febrile shivering" was published in The Journal of Physiology and received media coverage.
July 1, 2011: Ms. Yoshie Nakagawa joined the lab as a technical staff.
July 15, 2011: Kazu Nakamura's co-authoring paper "Tangential migration and proliferation of intermediate progenitors of GABAergic neurons in the mouse telencephalon" was published in Development.
June 12, 2011: Kazu Nakamura was invited to and joined the Review Editorial Board of Frontiers in Integrative Physiology.
April 25, 2011: An article introducing our laboratory was published in Neuroscience News of the Japan Neuroscience Society.
March 16, 2011: Dr. Naoya Kataoka joined the lab as a post-doctoral researcher.
February 10, 2011: Kazu Nakamura's research proposal was accepted by the Funding Program for Next Generation World-Leading Researchers (Japanese governmental funding).
January 10, 2011: Kazu Nakamura's review article (in Japanese) was published in Japanese Journal of Molecular Psychiatry.
January 1, 2011: Kazu Nakamura's co-authoring review article "Central neural pathways for thermoregulation" was published in Frontiers in Bioscience.
November 5, 2010: Kazu Nakamura was invited to and joined the Review Editorial Board of Frontiers in Neuroendocrine Science.
November 1, 2010: Kazu Nakamura's essay was published in the AFTERNOON TEA section of Journal of the Physiological Society of Japan.
October 1, 2010: Kazu Nakamura's essay was published in the AWARD section of Journal of the Physiological Society of Japan.
September 27, 2010: Kazu Nakamura's review article (in Japanese) "Mechanism of body temperature regulation" was published in The Autonomic Nervous System.
September 1, 2010: Ms. Chika Tanizawa joined the lab as a technical staff.
June 15, 2010: Kazu Nakamura's review article (in Japanese) "Central circuitry mechanism for thermoregulation" was published in Seitai no kagaku (Science of the Living Body).
May 21, 2010: Symposium "Temperature and Life: Progress in Thermal Physiology" (organized by Kazuhiro Nakamura & Makoto Tominaga) was held at the 87th Annual Meeting of the Physiological Society of Japan. Many thanks to the speakers and big audience!
May 20, 2010: Kazu Nakamura received the 11th Promotion Award of the Physiological Society of Japan.
May 18, 2010: Kazu Nakamura received 2010 Yas Kuno Memorial Award from the Environmental Physiology Group of the Physiological Society of Japan.
April 27, 2010: Kazu Nakamura's first-author paper "A thermosensory pathway mediating heat-defense responses" was published in Proceedings of the National Academy of Sciences of the United States of America (PNAS) and received media coverage.
April 1, 2010: Kazu Nakamura's research proposal was accepted in Grant-in-Aid for Young Scientists (A) by the Ministry of Education, Culture, Sports, Science and Technology of Japan.
April 26, 2010: Kazu Nakamura received 2010 New Investigator Award from the American Physiological Society (APS) Neural Control and Autonomic Regulation (NCAR) Section.
February, 2010: Kazu Nakamura's collaborative book chapter "The TRPV1 channel in normal thermoregulation: What have we learned from experiments using different tools?" was published in the book "Vanilloid Receptor TRPV1 in Drug Discovery: Targeting Pain and Other Pathological Disorders" (publisher, John & Wiley & Sons).
December 18, 2009: Kazu Nakamura's essay was published in Journal of the Physiological Society of Japan.
October 15, 2009: Kazu Nakamura's collaborative paper "Neutralization of granulocyte macrophage colony-stimulating factor decreases amyloid beta 1-42 and suppresses microglial activity in a transgenic mouse model of Alzheimer's disease" was published in Human Molecular Genetics.
October 14, 2009: Kazu Nakamura's collaborative paper "Granulocyte-macrophage colony-stimulating factor antibody suppresses microglial activity: implications for anti-inflammatory effects in Alzheimer's disease and multiple sclerosis" was published in Journal of Neurochemistry.
September 11, 2009: Kazu Nakamura's co-authoring review article "The transient receptor potential vanilloid-1 channel in thermoregulation: a thermosensor it is not" was published in Pharmacological Reviews.
July 26, 2009: Symposium "Neuronal mechanisms contributing to body temperature regulation" (organized by Kazuhiro Nakamura & Kei Nagashima) was held at the 3rd International Symposium on Physiology and Pharmacology of Temperature Regulation (PPTR2009). Many thanks to the speakers and big audience for the active discussions!
July 25, 2009: Yoshiko Nakamura received the 3rd International Symposium on Physiology and Pharmacology of Temperature Regulation Young Researcher Award.
June 30, 2009: Yoshiko Nakamura's first-author paper "Different populations of prostaglandin EP3 receptor-expressing preoptic neurons project to two fever-mediating sympathoexcitatory brain regions" was published in Neuroscience.
April 1, 2009: Nakamura Lab was launched!