IntSplice ver. 1.1

IntSplice predicts a splicing consequence of a single nucleotide variation (SNV) at intronic positions -50 to -3 close to the 3' end of an intron of the human genome. Compared to our previous ver. 1.0, ver. 1.1 has a different user interface and is much faster. Note that the predicted value of ver. 1.1 is slightly different from that of ver. 1.0 to expedite the calculation. Pre-processed genome-wide scores of IntSplice ver. 1.1 are available under the “Download” tab.

Genome assembly version 
Genomic coordinate Chr :  

Example. g.73550880G>A on chromosome 10 (GRCh37/hg19) or g.71791123G>A on chromosome 10 (GRCh38/hg38) identified in a patient with Usher syndrome is at the 9th nucleotide from the 3’ end of intron 45 of CDH23 [von Brederlow et al. Hum Mutat. 2002, Mar;19(3):268-73]

Previous version (ver. 1.0) is here.