InMeRF

The Individual Meta Random Forest (InMeRF) is a tool to predict the pathogenicity of nonsynonymous SNVs (nsSNVs) using 150 independent models that were individually generated for all possible amino acid (AA) substitutions. This version is using 34 rank scores in dbNSFP v4.0a as feature values.

Genome assembly version 
Genomic coordinate Chr :  
:



ex. Chr1:985853 (GRCh37/hg19) or Chr1:1050473 (GRCh38/hg38) in AGRN (ENSG00000188157, ENST00000379370, ENSP00000368678) exon 29, c.5023G>A predicting p.G1675S in the LG2 domain of agrin causes congenital myasthenic syndrome (Karakaya et al. J Clin Neuromuscul Dis 2017, 18: 147-151)