\uff11\uff0e\u7814\u7a76\u306e\u5bfe\u8c61
\n2000 \u5e74 4 \u6708 1 \u65e5\uff5e2028 \u5e74 12 \u6708 31 \u65e5\u307e\u3067\u306b\u982d\u9838\u90e8\u60aa\u6027\u672b\u68a2\u795e\u7d4c\u9798\u816b\uff08HNMPNST\uff09\u3068\u8a3a\u65ad\u3055\u308c\u3001\u540d\u53e4\u5c4b\u5927\u5b66\u533b\u5b66\u90e8\u9644\u5c5e\u75c5\u9662\u3067\u751f\u691c\u3001\u624b\u8853\u3092\u53d7\u3051\u3089\u308c\u305f\u60a3\u8005\u3055\u3093\u3067\u3059\u3002
\n\uff12\uff0e\u7814\u7a76\u76ee\u7684\u30fb\u65b9\u6cd5\u30fb\u7814\u7a76\u671f\u9593
\n\u7814\u7a76\u76ee\u7684\uff1a
\n\u982d\u9838\u90e8\u60aa\u6027\u672b\u68a2\u795e\u7d4c\u9798\u816b\uff08HN-MPNST\uff09\u306f\u975e\u5e38\u306b\u7a00\u306a\u816b\u760d\u3067\u3042\u308a\u3001\u9838\u90e8\u8089\u816b\u306e 2-14%\u7a0b\u5ea6\u3092\u5360\u3081\u308b\u3068\u8a00\u308f\u308c\u3066\u3044\u307e\u3059\u300250-60% \u306e\u75c7\u4f8b\u3067\u306f Neurofibromatosis type1(NF1) \u306b\u5408\u4f75\u3057\u300110%\u7a0b\u5ea6\u306f\u653e\u5c04\u7dda\u7167\u5c04\u65e2\u5f80\u304c\u8a98\u56e0\u3068\u306a\u308a\u3001\u6b8b\u308a\u306f\u5b64\u767a\u6027(De novo)\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002MPNST \u306e\u306a\u304b\u3067\u3001\u982d\u9838\u90e8\u539f\u767a(HN-MPNST)\u306f 12.3%, 5 \u5e74\u751f\u5b58\u7387\u306f52.6\uff05\u3068\u306e\u5831\u544a\u304c\u3042\u308a\u3001\u304b\u306a\u308a\u60aa\u6027\u5ea6\u306e\u9ad8\u3044\u75be\u60a3\u3067\u3042\u308b\u3068\u8a00\u3048\u307e\u3059\u3002\u305d\u306e\u4e00\u65b9\u3067 HNMPNST \u306f\u975e\u5e38\u306b\u7a00\u306a\u816b\u760d\u3067\u3042\u308a\u3001\u5927\u5b66\u75c5\u9662\u306a\u3069\u306e\u6bd4\u8f03\u7684\u898f\u6a21\u304c\u5927\u304d\u3044\u65bd\u8a2d\u3067\u3082\u5358\u4e00\u65bd\u8a2d\u3067\u306f\u5e74\u9593\u306b\uff11\u75c7\u4f8b\u7a0b\u5ea6\u7d4c\u9a13\u3059\u308b\u304b\u3069\u3046\u304b\u306e\u75be\u60a3\u3067\u3042\u308a\u3001\u60aa\u6027\u5ea6\u306f\u9ad8\u3044\u75be\u60a3\u3067\u3042\u308b\u3053\u3068\u306f\u8a8d\u8b58\u3055\u308c\u3066\u3044\u307e\u3057\u305f\u304c\u3001\u767a\u751f\u30e1\u30ab\u30cb\u30ba\u30e0\u306e\u89e3\u6790\u304c\u9032\u3093\u3067\u3044\u306a\u3044\u306e\u304c\u73fe\u72b6\u3067\u3059\u3002\u8fd1\u5e74\u3001MPNST \u306e\u3046\u3061\u7279\u306b\u9ad8\u3044\u60aa\u6027\u5ea6\u3092\u793a\u3059\u3082\u306e\u306f\u30dd\u30ea\u30b3\u30fc\u30e0\u8907\u5408\u4f53\u306e\u907a\u4f1d\u5b50\u5909\u7570\u304c\u3042\u308b\u3053\u3068\u304c\u793a\u5506\u3055\u308c\u3066\u304a\u308a\u3001\u4eca\u5f8c\u306e\u65b0\u305f\u306a\u6cbb\u7642\u30bf\u30fc\u30b2\u30c3\u30c8\u3068\u306a\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u672c\u7814\u7a76\u3067\u306f\u3001HN-MPNST \u306b\u3064\u3044\u3066\u3001\u30dd\u30ea\u30b3\u30fc\u30e0\u8907\u5408\u4f53\u306e\u907a\u4f1d\u5b50\u5909\u7570\u306b\u57fa\u3065\u304f\u816b\u760d\u767a\u751f\u30e1\u30ab\u30cb\u30ba\u30e0\u306e\u89e3\u6790\u3092\u884c\u3044\u3001\u65b0\u305f\u306a\u6cbb\u7642\u9078\u629e\u80a2\u306e\u958b\u767a\u306b\u7e4b\u3052\u308b\u3053\u3068\u3092\u76ee\u6307\u3057\u307e\u3059\u3002
\n\u7814\u7a76\u65b9\u6cd5\uff1a
\n\u901a\u5e38\u8a3a\u7642\u306b\u304a\u3044\u3066\u3001\u8a3a\u65ad\u3084\u6cbb\u7642\u306e\u305f\u3081\u306b\u7d44\u7e54\u3092\u751f\u691c\u307e\u305f\u306f\u624b\u8853\u306b\u3088\u308a\u5f97\u3089\u308c\u305f\u816b\u760d\u7d44\u7e54\u306e\u30b5\u30f3\u30d7\u30eb\u3092\u89e3\u6790\u3057\u307e\u3059\u3002\u305d\u306e\u816b\u760d\u7d44\u7e54\u304b\u3089 DNS\u3001RNA \u306e\u62bd\u51fa\u3092\u884c\u3044\u3001\u30dd\u30ea\u30b3\u30fc\u30e0\u95a2\u9023\u907a\u4f1d\u5b50\u7fa4\uff08EED\u3001EZH2\u3001SUZ12\u3001RbAp46\uff09\u306e\u907a\u4f1d\u5b50\u5909\u7570\u89e3\u6790\u3092\u884c\u3044\u307e\u3059\u3002\u307e\u305f\u3001\u60a3\u8005\u8a3a\u7642\u9332\u304b\u3089\u4e88\u5f8c\u60c5\u5831\u306a\u3069\u3092\u62bd\u51fa\u3057\u3001\u7d44\u7e54\u306e\u514d\u75ab\u67d3\u8272\uff08H3K27me3, SOX2, CD4, CD8,Ki-67 \u306a\u3069\uff09\u306b\u3088\u308b\u89e3\u6790\u3068\u4e88\u5f8c\u30c7\u30fc\u30bf\u306a\u3069\u3068\u306e\u76f8\u95a2\u691c\u8a0e\u3092\u884c\u3044\u307e\u3059\u3002<\/p>\n
\u7814\u7a76\u671f\u9593\uff1a \u5b9f\u65bd\u627f\u8a8d\u65e5 \uff5e 2029 \u5e74 3 \u6708 31 \u65e5<\/p>\n
\uff13\uff0e\u7814\u7a76\u306b\u7528\u3044\u308b\u8a66\u6599\u30fb\u60c5\u5831\u306e\u7a2e\u985e
\n\u30fb\u751f\u691c\u3001\u624b\u8853\u3067\u63a1\u53d6\u3057\u305f\u7d44\u7e54\u30b5\u30f3\u30d7\u30eb
\n\u30fb\u8a3a\u7642\u9332\u60c5\u5831\uff08\u5e74\u9f62\u3001\u6027\u5225\u3001\u81ea\u899a\u75c7\u72b6\u3001\u5bb6\u65cf\u6b74\u3001\u4f75\u5b58\u75be\u60a3\u3001\u816b\u760d\u306e\u90e8\u4f4d\u3084\u5927\u304d\u3055\u3001\u500b\u6570\u3001\u75c5\u60a9\u671f\u9593\u3001\u753b\u50cf\u691c\u67fb\u6240\u898b\u3001\u4e00\u6642\u6cbb\u7642\u52b9\u679c\u3001\u518d\u767a\u8ee2\u79fb\u306e\u6709\u7121\uff08\u6709\u308a\u306e\u5834\u5408\u306f\u305d\u306e\u90e8\u4f4d\u3068\u6642\u671f\uff09\u3001\u8ee2\u5e30\u306a\u3069\uff09
\n\u30fb\u4e00\u822c\u8eab\u4f53\u6240\u898b\uff08\u8840\u5727\u3001\u4f53\u91cd\u3001\u4f53\u6e29\u3001P.S.\uff09\u3001\u8840\u6db2\u691c\u67fb\uff08\u767d\u8840\u7403\u6570\u3001\u30d8\u30e2\u30b0\u30ed\u30d3\u30f3\u3001\u8840\u5c0f\u677f\u6570\u3001\u7dcf\u30bf\u30f3\u30d1\u30af\u3001\u30a2\u30eb\u30d6\u30df\u30f3\u3001AST\u3001ALT\u3001Na\u3001K\u3001Cl \u306a\u3069\uff09
\n\uff14\uff0e\u5916\u90e8\u3078\u306e\u8a66\u6599\u30fb\u60c5\u5831\u306e\u63d0\u4f9b
\n\u30c7\u30fc\u30bf\u306f\u533f\u540d\u5316\u3057\u3001\u5bfe\u5fdc\u8868\u3092\u4f5c\u6210\u3057\u307e\u3059\u3002\u5bfe\u5fdc\u8868\u306f\u3001\u672c\u5b66\u306e\u7814\u7a76\u8cac\u4efb\u8005\u304c\u4fdd\u7ba1\u30fb\u7ba1\u7406\u3057\u307e\u3059\u3002
\n\u307e\u305f\u8a66\u6599\u306f\u3001\u500b\u4eba\u3092\u7279\u5b9a\u3067\u304d\u306a\u3044\u3088\u3046\u306b\u52a0\u5de5\u3057\u305f\u4e0a\u3067\u3001\u5171\u540c\u7814\u7a76\u6a5f\u95a2\uff08\u5c90\u961c\u5927\u5b66\u533b\u5b66\u90e8\u9644\u5c5e\u75c5\u9662\uff09\u306b\u76f4\u63a5\u306e\u624b\u6e21\u3057\u307e\u305f\u306f\u90f5\u9001\u3057\u3066\u3001\u89e3\u6790\u3092\u884c\u3044\u307e\u3059\u3002
\n\uff15\uff0e\u7814\u7a76\u7d44\u7e54
\n\u5c90\u961c\u5927\u5b66\u5927\u5b66\u9662\u533b\u5b66\u7cfb\u7814\u7a76\u79d1 \u8033\u9f3b\u54bd\u5589\u79d1\u30fb\u982d\u9838\u90e8\u5916\u79d1 \u67f4\u7530 \u535a\u53f2
\n\u540d\u53e4\u5c4b\u5927\u5b66\u5927\u5b66\u9662\u533b\u5b66\u7cfb\u7814\u7a76\u79d1 \u8033\u9f3b\u54bd\u5589\u79d1 \u897f\u5c3e \u76f4\u6a39
\n\uff16\uff0e\u304a\u554f\u3044\u5408\u308f\u305b\u5148
\n\u672c\u7814\u7a76\u306b\u95a2\u3059\u308b\u3054\u8cea\u554f\u7b49\u304c\u3042\u308a\u307e\u3057\u305f\u3089\u4e0b\u8a18\u306e\u9023\u7d61\u5148\u307e\u3067\u304a\u554f\u3044\u5408\u308f\u305b\u4e0b\u3055\u3044\u3002
\n\u3054\u5e0c\u671b\u304c\u3042\u308c\u3070\u3001\u4ed6\u306e\u7814\u7a76\u5bfe\u8c61\u8005\u306e\u500b\u4eba\u60c5\u5831\u53ca\u3073\u77e5\u7684\u8ca1\u7523\u306e\u4fdd\u8b77\u306b\u652f\u969c\u304c\u306a\u3044\u7bc4\u56f2\u5185\u3067\u3001\u7814\u7a76\u8a08\u753b\u66f8\u53ca\u3073\u95a2\u9023\u8cc7\u6599\u3092\u95b2\u89a7\u3059\u308b\u3053\u3068\u304c\u51fa\u6765\u307e\u3059\u306e\u3067\u304a\u7533\u51fa\u4e0b\u3055\u3044\u3002
\n\u307e\u305f\u3001\u8a66\u6599\u30fb\u60c5\u5831\u304c\u5f53\u8a72\u7814\u7a76\u306b\u7528\u3044\u3089\u308c\u308b\u3053\u3068\u306b\u3064\u3044\u3066\u60a3\u8005\u3055\u3093\u3082\u3057\u304f\u306f\u60a3\u8005\u3055\u3093\u306e\u4ee3\u7406\u4eba\u306e\u65b9\u306b\u3054\u4e86\u627f\u3044\u305f\u3060\u3051\u306a\u3044\u5834\u5408\u306b\u306f\u7814\u7a76\u5bfe\u8c61\u3068\u3057\u307e\u305b\u3093\u306e\u3067\u3001\u4e0b\u8a18\u306e\u9023\u7d61\u5148\u307e\u3067\u304a\u7533\u51fa\u304f\u3060\u3055\u3044\u3002\u305d\u306e\u5834\u5408\u3067\u3082\u60a3\u8005\u3055\u3093\u306b\u4e0d\u5229\u76ca\u304c\u751f\u3058\u308b\u3053\u3068\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n
<\/p>\n
\u7167\u4f1a\u5148\u304a\u3088\u3073\u7814\u7a76\u3078\u306e\u5229\u7528\u3092\u62d2\u5426\u3059\u308b\u5834\u5408\u306e\u9023\u7d61\u5148\uff1a
\n\u611b\u77e5\u770c\u540d\u53e4\u5c4b\u5e02\u662d\u548c\u533a\u9db4\u821e\u753a 65
\n052-744-2323
\n\u540d\u53e4\u5c4b\u5927\u5b66\u5927\u5b66\u9662\u533b\u5b66\u7cfb\u7814\u7a76\u79d1 \u8033\u9f3b\u54bd\u5589\u79d1 \u51c6\u6559\u6388 \u897f\u5c3e \u76f4\u6a39
\n\u7814\u7a76\u4ee3\u8868\u8005\uff1a\u5c90\u961c\u5927\u5b66\u5927\u5b66\u9662\u533b\u5b66\u7cfb\u7814\u7a76\u79d1 \u8033\u9f3b\u54bd\u5589\u79d1\u30fb\u982d\u9838\u90e8\u5916\u79d1 \u67f4\u7530 \u535a\u53f2<\/p>\n","protected":false},"excerpt":{"rendered":"
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